]> 2.24 Bioportal mappings to BRENDA tissue / enzyme source (BTO) verunknown Bioportal mappings to Cell type (CL) verunknown Bioportal mappings to Chemical entities of biological interest (CHEBI) verunknown Bioportal mappings to Drosophila gross anatomy (FBbt) ver2011-02-10 Bioportal mappings to Foundational Model of Anatomy (FMA) ver3.1 Bioportal mappings to Gene Ontology (GO) ver1.886 Bioportal mappings to Human disease (DOID) ver Bioportal mappings to International Classification of Diseases (ICD-9) ver9 Bioportal mappings to MGED Ontology (MO) ver1.3.1.1 Bioportal mappings to Malaria Ontology (IDOMAL) ver1.22 Bioportal mappings to Mammalian phenotype (MP) vernull Bioportal mappings to Medical Subject Headings (MSH) ver2011_2010_08_30 Bioportal mappings to Microarray experimental conditions (MO) ver1.3.1.1 Bioportal mappings to Minimal anatomical terminology (MAT) ver1.1 Bioportal mappings to Mosquito gross anatomy (TGMA) verunknown Bioportal mappings to NCBI organismal classification (NCBITaxon) ver1.2 Bioportal mappings to NCI Thesaurus (NCIt) ver11.01e Bioportal mappings to NIFSTD (nif) ver2.2 - December 20, 2010 Bioportal mappings to Ontology for Biomedical Investigations (OBI) ver2010-10-26 Vancouver 2010 release, RC2 Bioportal mappings to Phenotypic quality (PATO) vernull Bioportal mappings to SNOMED Clinical Terms (SNOMEDCT) ver2010_07_31 Bioportal mappings to Teleost Anatomy Ontology (TAO) vernull Bioportal mappings to Teleost anatomy and development (TAO) ver1.158 Bioportal mappings to Units of measurement (UO) vernull Bioportal mappings to Zebrafish anatomy and development (ZFA) verunknown Date: 11th May 2012 Ele Holloway Helen Parkinson James Malone Mappings to Plant structure (PO) Mappings: CRISP Thesaurus Version 2.5.2.0 Mappings: The Jackson Lab Mappings:The Arabidopsis Information Resource (TAIR) Tomasz Adamusiak Dani Welter Natalja Kurbatova A definition citation is a document, ontology class, person or organization from which the definition of the class is derived. It is used in the same sense as a citation in literature, in that the definition may have been derived from these sources or that this definition is related to these source. is about has_input http://www.ebi.ac.uk/efo/has_input is_input_of http://www.ebi.ac.uk/efo/is_input_of has_quality http://www.ebi.ac.uk/efo/has_quality has_output is_realized_by Relation between a realizable entity and a process. Reciprocal relation of realizes http://www.ebi.ac.uk/efo/is_realized_by realizes Relation between a process and a material fulfilling a role (i.e. realizing a role within the context of the process). For example a human realizing role of teacher within a lesson teching process. http://www.ebi.ac.uk/efo/realizes has_role A relation between a continuant C and a role R. The reciprocal relation of role_of. http://www.ebi.ac.uk/efo/has_role bearer_of A relation between an entity and a dependent continuant; the reciprocal relation of inheres_in [GOC:cjm] example of usage: red eye bearer_of redness http://www.ebi.ac.uk/efo/EFO_0001377 inheres_in http://www.ebi.ac.uk/efo/EFO_0000829 role_of http://www.ebi.ac.uk/efo/is_role_of has_tumor_type is_tumor_of has_disease_location is_location_of_disease is_broader_than relationship is_unit_of has_unit has_flag Relation to flag that an EFO class qualifies as an Atlas validation type http://www.ebi.ac.uk/efo/has_flag is_executed_in contained_in Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. http://www.ebi.ac.uk/efo/contained_in contains http://www.ebi.ac.uk/efo/contains derived_into http://www.ebi.ac.uk/efo/derived_into derives_from Derivation as a relation between instances. The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Derivation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant. http://www.ebi.ac.uk/efo/derives_from has_part EFO_0000823 http://www.ebi.ac.uk/efo/has_part has_participant Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the A continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. located_in http://www.ebi.ac.uk/efo/located_in location_of http://www.ebi.ac.uk/efo/location_of part_of EFO_0000822 For continuants: C part_of C' if and only if: given any c that instantiates C at a time t, there is some c' such that c' instantiates C' at time t, and c *part_of* c' at t. For processes: P part_of P' if and only if: given any p that instantiates P at a time t, there is some p' such that p' instantiates P' at time t, and p *part_of* p' at t. (Here *part_of* is the instance-level part-relation.) http://www.ebi.ac.uk/efo/part_of participates_in Participates in is a primitive instance-level relation between a continuant and a process in which it participates. For example a scanner participates in a scanning process at some specific time. myoblast cell line BrendaTissueOBO HMEpC cell HMEC cell human mammary epithelial cell "Human Mammary Epithelial Cells (HMEpC) are derived from normal adult mammary glands." [Cell Applications Inc.:http\://cellapplications.com/] BrendaTissueOBO human mammary epithelial cell HMEC cell 184A1N4 cell A1N4 cell A1N4 cell "The 184A1N4 and 184B5 cell lines are nontumorigenic cell lines derived from primary cultures of HMECs that were immortalized with benzo(a)pyrene." [PMID:15827326] BrendaTissueOBO 184B5 cell BrendaTissueOBO "The 184A1N4 and 184B5 cell lines are nontumorigenic cell lines derived from primary cultures of HMECs that were immortalized with benzo(a)pyrene." [PMID:15827326] RBA-2 cell BrendaTissueOBO "Rat brain-derived type-2 astrocyte cell line." [PMID:14575868] COM-3 cell COM3 cell BrendaTissueOBO COM3 cell "A differentiating cell line, established from the mouse myoblastic cell line C2C12." [PMID:9227903] INC-2 cell INC2 cell BrendaTissueOBO "A non-differentiating cell line, established from the mouse myoblastic cell line C2C12." [PMID:9227903] INC2 cell norfloxacin 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid Jon Ison NFLX http://www.ebi.ac.uk/efo/EFO_0003174 CiteXplore:6224685 "PubMed citation" 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure "A synthetic fluoroquinolone with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase." [] Wikipedia:Norfloxacin "Wikipedia" 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid Patent:US4146719 "Patent" ChemIDplus:70458-96-7 "CAS Registry Number" ChEMBL:100246 "ChEMBL COMPOUND" Patent:DE2840910 "Patent" Patent:US4292317 "Patent" CHEBI:7629 CiteXplore:6454381 "PubMed citation" KEGG COMPOUND:70458-96-7 "CAS Registry Number" Patent:BE863429 "Patent" CiteXplore:6211142 "PubMed citation" CiteXplore:3908074 "PubMed citation" 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid CiteXplore:6461606 "PubMed citation" NFLX Gmelin:1576626 "Gmelin Registry Number" KEGG COMPOUND:C06687 "KEGG COMPOUND" KEGG DRUG:D00210 "KEGG DRUG" Beilstein:567897 "Beilstein Registry Number" CiteXplore:6234465 "PubMed citation" DrugBank:DB01059 "DrugBank" CiteXplore:3317294 "PubMed citation" NFLX 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid warfarin (Phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine 1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)- 3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin 3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin 3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin 4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one Beilstein:1293536 C19H16O4 CC(=O)CC(c1ccccc1)c1c(O)c2ccccc2oc1=O Coumafene DrugBank:DB00682 InChI=1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3 InChIKey=PJVWKTKQMONHTI-UHFFFAOYSA-N Patent:US2427578 Patent:US2765321 Patent:US2777859 Patent:US3239529 Warf 10 Wikipedia:Warfarin Zoocoumarin true warfarin warfarina warfarine warfarinum vitamin A true S-adenosyl-L-methionine (3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine, inner salt Acylcarnitine AdoMet Beilstein:3576439 C15H23N6O5S COMe:MOL000172 C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 ChemIDplus:29908-03-0 InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7-,8+,10+,11+,14+,27?/m0/s1 InChIKey=MEFKEPWMEQBLKI-AIRLBKTGSA-O KEGG COMPOUND:29908-03-0 KEGG COMPOUND:C00019 S-(5'-deoxyadenosin-5'-yl)-L-methionine S-Adenosyl-L-methionine S-Adenosylmethionine S-adenosyl-L-methionine S-adenosylmethionine SAM SAMe [(3S)-3-amino-3-carboxypropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonium [1-(adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl][(3S)-3-amino-3-carboxypropyl](methyl)sulfonium true phosphatidylethanolamine (3-Phosphatidyl)-ethanolamine (3-Phosphatidyl)ethanolamine 1,2-diacyl-sn-glycero-3-phosphoethanolamine 1-Acyl-2-acyl-sn-glycero-3-phosphoethanolamine C7H12NO8PR2 Cephalin CiteXplore:10540156 CiteXplore:3196084 CiteXplore:7980848 KEGG COMPOUND:C00350 LIPID MAPS:LMGP02010000 NCCOP(O)(=O)OCC(COC([*])=O)OC([*])=O O-(1-beta-Acyl-2-acyl-sn-glycero-3-phospho)ethanolamine PDBeChem:PTY Phosphatidylethanolamine phosphatidyl(amino)ethanols phosphatidylethanolamines true phospholipid C5H6O8PR3 KEGG COMPOUND:C00865 Phospholipid phospholipid derivative phospholipids true creatinine 1-Methylglycocyamidine 1-methylglycocyamidine 2-imino-1-methylimidazolidin-4-one C4H7N3O CN1CC(=O)NC1=N ChemIDplus:60-27-5 Creatinine InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8) InChIKey=DDRJAANPRJIHGJ-UHFFFAOYSA-N KEGG COMPOUND:60-27-5 KEGG COMPOUND:C00791 Kreatinin NIST Chemistry WebBook:60-27-5 creatinina creatinine true dehydroepiandrosterone sulfate (3-beta)-3-(Sulfooxy)androst-5-en-17-one 17-Ketoandrost-5-en-3beta-yl sulfate 17-oxoandrost-5-en-3beta-yl hydrogen sulfate 17-oxoandrost-5-en-3beta-yl hydrogen sulphate 3-O-Sulfodehydroepiandrosterone 3beta-Hydroxyandrost-5-en-17-one 3-sulfate 3beta-hydroxyandrost-5-en-17-one 3-sulfate Androst-5-en-17-on-3beta-yl sulfuric acid C19H28O5S ChemIDplus:651-48-9 CiteXplore:18307294 CiteXplore:9661815 DHEA sulfate DHEA-S DHEAS Dehydroepiandrosterone 3-sulfate Dehydroepiandrosterone monosulfate Dehydroepiandrosterone sulfate Dehydroepiandrosterone sulphate Dehydroisoandrosterone sulfate Dehydroisoandrosterone-3-sulfate InChI=1S/C19H28O5S/c1-18-9-7-13(24-25(21,22)23)11-12(18)3-4-14-15-5-6-17(20)19(15,2)10-8-16(14)18/h3,13-16H,4-11H2,1-2H3,(H,21,22,23)/t13-,14-,15-,16-,18-,19-/m0/s1 InChIKey=CZWCKYRVOZZJNM-USOAJAOKSA-N KEGG COMPOUND:C04555 LIPID MAPS:LMST05020010 Prasterone sulfate [H][C@@]12CC=C3C[C@H](CC[C@]3(C)[C@@]1([H])CC[C@]1(C)C(=O)CC[C@@]21[H])OS(O)(=O)=O true bilirubin 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid 2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione Beilstein:74376 Bilirubin C33H36N4O6 CC1=C(C=C)\\C(NC1=O)=C\\c1[nH]c(Cc2[nH]c(\\C=C3NC(=O)C(C=C)=C/3C)c(C)c2CCC(O)=O)c(CCC(O)=O)c1C ChemIDplus:635-65-4 Gmelin:411033 InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14- InChIKey=BPYKTIZUTYGOLE-IFADSCNNSA-N KEGG COMPOUND:635-65-4 KEGG COMPOUND:C00486 bilirubin bilirubin IXalpha true glycoprotein Glycoprotein Glykoprotein Glykoproteine KEGG COMPOUND:C00326 [glycoprotein] glicoproteina glicoproteinas glycoproteine glycoproteines glycoproteins true homocysteine 2-Amino-4-mercaptobutyric acid 2-amino-4-sulfanylbutanoic acid C4H9NO2S Hcy Homocysteine InChI=1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7) InChIKey=FFFHZYDWPBMWHY-UHFFFAOYSA-N KEGG COMPOUND:C05330 NC(CCS)C(O)=O homocysteine true 2-acetylaminofluorene 2-AAF 2-Acetamidofluorene 2-FAA 2-acetamidofluorene Jon Ison N-2-Fluorenylacetamide N-fluoren-2-ylacetamide http://www.ebi.ac.uk/efo/EFO_0003190 NIST Chemistry WebBook:53-96-3 "CAS Registry Number" Wikipedia:2-Acetylaminofluorene "Wikipedia" 2-AAF CHEBI:11494 2-FAA KEGG COMPOUND:C02778 "KEGG COMPOUND" CHEBI:981 KEGG COMPOUND:53-96-3 "CAS Registry Number" "An ortho-fused polycyclic arene that consists of 9H-fluorene bearing an acetamido substituent at position 2." [] CHEBI:40645 N-2-Fluorenylacetamide CHEBI:19431 Reaxys:2807677 "Reaxys Registry Number" 2-Acetamidofluorene Beilstein:2807677 "Beilstein Registry Number" ChemIDplus:53-96-3 "CAS Registry Number" N-fluoren-2-ylacetamide 2-FAA N-2-Fluorenylacetamide 2-Acetamidofluorene 2-AAF N-fluoren-2-ylacetamide sphingomyelin C24H49N2O6PR CCCCCCCCCCCCC\\C=C\\[C@@H](O)[C@H](COP(O)(=O)OCC[N+](C)(C)C)NC([*])=O CiteXplore:3196084 KEGG COMPOUND:C00550 N-acyl-4-sphingenyl-1-O-phosphorylcholines Sphingomyelin ceramide phosphocholine sphingomyelins true ceramide C19H36NO3R Cer Ceramide CiteXplore:7542630 KEGG COMPOUND:C00195 LIPID MAPS:LMSP02 N-acylated sphingoid Wikipedia:Ceramide ceramides true triglyceride C6H5O6R3 KEGG COMPOUND:C00422 LIPID MAPS:LMGL0301 Triacylglycerol Triglycerid Triglyceride Triglyzerid [*]C(=O)OCC(COC([*])=O)OC([*])=O triacylglycerols triglycerides true polysaccharide Glycan Glycane Glykan Glykane KEGG COMPOUND:C00420 Polysaccharide glycans polisacarido polisacaridos polysaccharide polysaccharides true tyrosine 2-Amino-3-(p-hydroxyphenyl)propionic acid 2-amino-3-(4-hydroxyphenyl)propanoic acid 3-(p-Hydroxyphenyl)alanine Beilstein:515881 C9H11NO3 ChemIDplus:55520-40-6 Gmelin:27744 InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13) InChIKey=OUYCCCASQSFEME-UHFFFAOYSA-N KEGG COMPOUND:C01536 NC(Cc1ccc(O)cc1)C(O)=O Tyr Tyrosin Tyrosine tirosina true tyrosine antiviral benzodiazepine benzodiazepines true calcium 20Ca Ca Calcium ChEBI:C00076 ChemIDplus:7440-70-2 InChI=1S/Ca.2H InChIKey=FAQLAUHZSGTTLN-UHFFFAOYSA-N Kalzium WebElements:Ca [Ca] calcio true carbohydrate Kohlenhydrat Kohlenhydrate carbohidrato carbohidratos carbohydrate carbohydrates glucide glucides glucido glucidos hydrates de carbone saccharide saccharides saccharidum true coenzyme coenzyme coenzymes chemical entity true organic heterocyclic compound organic heterocycle organic heterocyclic compounds lysine 2,6-diaminohexanoic acid Beilstein:1616991 C6H14N2O2 ChemIDplus:70-54-2 Gmelin:279284 InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10) InChIKey=KDXKERNSBIXSRK-UHFFFAOYSA-N Lysin NCCCCC(N)C(O)=O NIST Chemistry WebBook:70-54-2 alpha,epsilon-diaminocaproic acid lysine true magnesium 12Mg ChEBI:C00305 ChemIDplus:7439-95-4 Gmelin:16207 InChI=1S/Mg.2H InChIKey=RSHAOIXHUHAZPM-UHFFFAOYSA-N Magnesium Mg WebElements:Mg [Mg] magnesio true sodium cholate Jon Ison cholic acid, monosodium salt http://www.ebi.ac.uk/efo/EFO_0003217 sodium cholate sodium cholate hydrate "A cholate salt that has formula C24H39NaO5." [] sodium cholate ChemIDplus:361-09-1 "CAS Registry Number" cholic acid, monosodium salt Beilstein:4289807 "Beilstein Registry Number" cholic acid, monosodium salt sodium cholate uric acid 2,6,8-trihydroxypurine C5H4N4O3 ChemIDplus:69-93-2 Harnsaeure lithic acid true folic acid Beilstein:100781 C19H19N7O6 ChEMBL:18788725 ChemIDplus:59-30-3 CiteXplore:17784727 FOLIC ACID Folate Folic acid Folsaeure InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1 InChIKey=OVBPIULPVIDEAO-LBPRGKRZSA-N KEGG COMPOUND:59-30-3 KEGG COMPOUND:C00504 MetaCyc:CPD-12826 N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid N-pteroyl-L-glutamic acid NIST Chemistry WebBook:59-30-3 Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)nc2c(=O)[nH]1 PDBeChem:FOL PGA PteGlu Pteroylglutamic acid Wikipedia:Folic_Acid pteroyl-L-glutamic acid pteroyl-L-monoglutamic acid true vitamin Bc vitamin M detergent A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions. Dani Welter phenylalanine 2-amino-3-phenylpropanoic acid Beilstein:1910407 C9H11NO2 ChemIDplus:150-30-1 Gmelin:50836 InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12) InChIKey=COLNVLDHVKWLRT-UHFFFAOYSA-N KEGG COMPOUND:C02057 NC(Cc1ccccc1)C(O)=O NIST Chemistry WebBook:150-30-1 Phenylalanin Phenylalanine alpha-Amino-beta-phenylpropionic acid fenilalanina phenylalanine true docosahexaenoic acid (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid 22:6(n-3) 22:6-4, 7,10,13,16,19 4,7,10,13,16,19-Docosahexaenoic acid 4,7,10,13,16,19-docosahexaenoic acid Beilstein:1715505 C22H32O2 CC\\C=C/C\\C=C/C\\C=C/C\\C=C/C\\C=C/C\\C=C/CCC(O)=O ChemIDplus:6217-54-5 CiteXplore:12359365 CiteXplore:12538082 CiteXplore:18072818 CiteXplore:18220672 CiteXplore:21045096 DHA DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID Doconexent Docosahexaenoic acid InChI=1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18- InChIKey=MBMBGCFOFBJSGT-KUBAVDMBSA-N KEGG COMPOUND:C06429 LIPID MAPS:LMFA01030185 PDBeChem:HXA all-cis-4,7,10,13,16,19-docosahexaenoic acid all-cis-DHA all-cis-docosa-4,7,10,13,16,19-hexaenoic acid cervonic acid docosahexaenoic acids true piperazine Beilstein:102555 C1CNCCN1 C4H10N2 ChemIDplus:110-85-0 Diethylenediamine Gmelin:25695 InChI=1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2 InChIKey=GLUUGHFHXGJENI-UHFFFAOYSA-N KEGG COMPOUND:110-85-0 KEGG COMPOUND:C07973 KEGG DRUG:D00807 NIST Chemistry WebBook:110-85-0 Piperazine Vermizine (TN) Wikipedia:Piperazine piperazine piperazines true phosphorus 15P ChemIDplus:7723-14-0 Gmelin:16235 InChI=1S/P InChIKey=OAICVXFJPJFONN-UHFFFAOYSA-N KEGG COMPOUND:7723-14-0 KEGG COMPOUND:C06262 P Phosphor Phosphorus WebElements:P [P] fosforo phosphore true serotonin 3-(2-Aminoethyl)-1H-indol-5-ol 3-(2-aminoethyl)-1H-indol-5-ol 5-HT 5-Hydroxytryptamine Beilstein:143524 C10H12N2O ChemIDplus:50-67-9 Enteramine Gmelin:1861995 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 InChIKey=QZAYGJVTTNCVMB-UHFFFAOYSA-N KEGG COMPOUND:50-67-9 KEGG COMPOUND:C00780 NCCc1c[nH]c2ccc(O)cc12 PDBeChem:SRO SEROTONIN Serotonin serotonine thrombocytin thrombotonin true phytosterol (22E)-stigmasta-5,22-dien-3beta-ol (3beta,22E)-stigmasta-5,22-dien-3-ol 5,22-Cholestadien-24-ethyl-3beta-ol Beilstein:2568182 C29H48O ChemIDplus:83-48-7 CiteXplore:13318319 CiteXplore:13547565 HMDB:HMDB00937 InChI=1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-10,19-21,23-27,30H,7,11-18H2,1-6H3/b9-8+/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1 InChIKey=HCXVJBMSMIARIN-PHZDYDNGSA-N KEGG COMPOUND:83-48-7 KEGG COMPOUND:C05442 LIPID MAPS:LMST01040123 NIST Chemistry WebBook:83-48-7 Phytosterol Reaxys:2568182 Stigmasterol Wikipedia:Stigmasterol [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\\C=C\\[C@@H](CC)C(C)C beta-stigmasterol phytosterols poriferasterol stigmasta-5,22-dien-3beta-ol true thyroxine 2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid Beilstein:2228514 C15H11I4NO4 ChemIDplus:300-30-1 CiteXplore:15206581 DL-Thyroxine InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23) InChIKey=XUIIKFGFIJCVMT-UHFFFAOYSA-N NC(Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-DL-tyrosine Thx thyroxine true apomorphine hydrochloride (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol hydrochlorid 6abeta-Aporphine-10,11-diol hydrochloride hemihydrate Apmorphine hydrochloride hemihydrate Apomorphin hydrochlorid wasser (2/1) Apomorphine HCl Jon Ison R-(-)-apomorphine hydrochloride http://www.ebi.ac.uk/efo/EFO_0003221 ChemIDplus:41372-20-7 "CAS Registry Number" "A hydrate that has formula C34H38Cl2N2O5." [] 6abeta-Aporphine-10,11-diol hydrochloride hemihydrate Apmorphine hydrochloride hemihydrate Apomorphine HCl KEGG DRUG:D02004 "KEGG DRUG" DrugBank:DB00714 "DrugBank" (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol hydrochlorid Apomorphin hydrochlorid wasser (2/1) Apomorphine HCl (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol hydrochlorid Apmorphine hydrochloride hemihydrate 6abeta-Aporphine-10,11-diol hydrochloride hemihydrate Apomorphin hydrochlorid wasser (2/1) element atom atome atomo atoms atomus elements fertilizer amino acid Aminocarbonsaeure Aminokarbonsaeure Aminosaeure amino acids true antidepressant alpha-adrenergic agonist isoxazole 1,2-oxazole 1-oxa-2-azacyclopentadiene Beilstein:103773 C3H3NO ChemIDplus:288-14-2 Gmelin:1041679 InChI=1S/C3H3NO/c1-2-4-5-3-1/h1-3H InChIKey=CTAPFRYPJLPFDF-UHFFFAOYSA-N NIST Chemistry WebBook:288-14-2 c1cnoc1 isooxazole isoxazole isoxazoles true antineoplastic agent antibacterial drug citalopram 1,3-dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile 1-(3-(dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile Beilstein:1397373 C20H21FN2O CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1 ChemIDplus:59729-33-8 Cipram Citalopram DrugBank:DB00215 InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3 InChIKey=WSEQXVZVJXJVFP-UHFFFAOYSA-N KEGG COMPOUND:59729-33-8 KEGG COMPOUND:C07572 Lu 10-171 NIST Chemistry WebBook:59729-33-8 Nitalapram Patent:DE2657013 Patent:EP0171943 Patent:EP1506963 Patent:US4136193 Wikipedia:Citalopram citalopram citalopramum true clozapine 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Beilstein:0764984 C18H19ClN4 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 ChemIDplus:5786-21-0 Clozapin Clozapine DrugBank:DB00363 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 InChIKey=QZUDBNBUXVUHMW-UHFFFAOYSA-N KEGG COMPOUND:C06924 KEGG DRUG:D00283 Patent:FR1334944 Patent:NL293201 Patent:US3539573 Wikipedia:Clozapine clozapina clozapine clozapinum true (1->3)-beta-D-glucan (1,3-beta-D-Glucosyl)n (1,3-beta-D-Glucosyl)n+1 (1,3-beta-D-Glucosyl)n-1 (1,3-beta-D-glucosyl)n 1,3-beta-D-Glucan 1,3-beta-Glucan Jon Ison callose curdlan http://www.ebi.ac.uk/efo/EFO_0003286 zymosan KEGG COMPOUND:C00965 "KEGG COMPOUND" CHEBI:10802 1,3-beta-Glucan CHEBI:10800 (1,3-beta-D-Glucosyl)n-1 (1,3-beta-D-Glucosyl)n+1 zymosan (1,3-beta-D-Glucosyl)n CHEBI:530 (1,3-beta-D-glucosyl)n 1,3-beta-D-Glucan CHEBI:18922 curdlan "A beta-D-glucan in which the glucose units are connected by (1->3) linkages." [] CHEBI:60750 callose (1,3-beta-D-Glucosyl)n+1 1,3-beta-D-Glucan (1,3-beta-D-Glucosyl)n-1 (1,3-beta-D-glucosyl)n (1,3-beta-D-glucosyl)n zymosan curdlan callose (1,3-beta-D-Glucosyl)n 1,3-beta-Glucan alpha-adrenergic antagonist An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. CHEBI:37890 James Malone alpha-adrenergic antagonists alpha-adrenergic blocker alpha-adrenergic blockers alpha-adrenergic receptor blockaders alpha-adrenoceptor antagonists http://www.ebi.ac.uk/efo/EFO_0001863 Jon Ison antimalarial anti-arrhythmia drug dibenzothiazepine dibenzothiazepines true allopurinol 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidine-4-one 1H-Pyrazolo(3,4-d)pyrimidin-4-ol 1H-pyrazolo[3,4-d]pyrimidin-4-ol 4'-Hydroxypyrazolol(3,4-d)pyrimidine 4-HPP 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidine 4-Hydroxy-3,4-pyrazolopyrimidine 4-Hydroxypyrazolo(3,4-d)pyrimidine 4-Hydroxypyrazolopyrimidine 4-Hydroxypyrazolyl(3,4-d)pyrimidine 4H-Pyrazolo(3,4-d)pyrimidin-4-one AL-100 Allopurinol Allopurinolum Alopurinol Beilstein:608611 C5H4N4O ChemIDplus:315-30-0 CiteXplore:7602118 DrugBank:DB00437 InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10) InChIKey=OFCNXPDARWKPPY-UHFFFAOYSA-N KEGG DRUG:315-30-0 KEGG DRUG:D00224 NIST Chemistry WebBook:315-30-0 Oc1ncnc2[nH]ncc12 Wikipedia:Allopurinol Zyloprim (TN) true 10-trans,12-cis-octadecadienoic acid (E,Z)-octadeca-10,12-dienoic acid 10,12-trans,cis-octadecanoic acid 10-trans-12-cis-CLA 10-trans-12-cis-conjugated linoleic acid 10-trans-12-cis-linoleic acid 10-trans-12-cis-octadecadienoic acid C18:2, n-6,8 cis,trans Jon Ison http://www.ebi.ac.uk/efo/EFO_0003287 trans-10,cis-12-conjugated linoleic acid 10-trans-12-cis-octadecadienoic acid "An octadeca-10,12-dienoic acid having 10-trans,12-cis-configuration." [] 10-trans-12-cis-conjugated linoleic acid C18:2, n-6,8 cis,trans 10-trans-12-cis-CLA 10,12-trans,cis-octadecanoic acid 10-trans-12-cis-linoleic acid CHEBI:44522 CHEBI:38395 PDBeChem:ODD "PDBeChem" (E,Z)-octadeca-10,12-dienoic acid Reaxys:1726562 "Reaxys Registry Number" LIPID MAPS:LMFA01030125 "LIPID MAPS instance" 10-trans-12-cis-linoleic acid 10-trans-12-cis-conjugated linoleic acid 10,12-trans,cis-octadecanoic acid 10-trans-12-cis-CLA (E,Z)-octadeca-10,12-dienoic acid 10-trans-12-cis-octadecadienoic acid C18:2, n-6,8 cis,trans tacrine 1,2,3,4-tetrahydro-9-acridinamine 1,2,3,4-tetrahydro-9-aminoacridine 5-amino-6,7,8,9-tetrahydroacridine 9-amino-1,2,3,4-tetrahydroacridine Jon Ison TACRINE Tacrine http://www.ebi.ac.uk/efo/EFO_0003170 tetrahydroaminacrine KEGG COMPOUND:321-64-2 "CAS Registry Number" PDBeChem:THA "PDBeChem" CHEBI:45978 NIST Chemistry WebBook:321-64-2 "CAS Registry Number" ChemIDplus:321-64-2 "CAS Registry Number" TACRINE 1,2,3,4-tetrahydro-9-aminoacridine "An aromatic amine that has formula C13H14N2." [] CHEBI:9389 Beilstein:147610 "Beilstein Registry Number" tetrahydroaminacrine Wikipedia:Tacrine "Wikipedia" KEGG COMPOUND:C01453 "KEGG COMPOUND" 5-amino-6,7,8,9-tetrahydroacridine Tacrine 1,2,3,4-tetrahydro-9-acridinamine 9-amino-1,2,3,4-tetrahydroacridine 9-amino-1,2,3,4-tetrahydroacridine tetrahydroaminacrine 1,2,3,4-tetrahydro-9-acridinamine 1,2,3,4-tetrahydro-9-aminoacridine TACRINE 5-amino-6,7,8,9-tetrahydroacridine Tacrine paracetamol 4'-hydroxyacetanilide 4-(Acetylamino)phenol 4-acetamidophenol APAP Acenol Acetaminofen Acetaminophen Beilstein:2208089 C8H9NO2 CC(=O)Nc1ccc(O)cc1 ChemIDplus:103-90-2 CiteXplore:11304127 CiteXplore:16716555 CiteXplore:21108564 CiteXplore:7602118 DrugBank:DB00316 HMDB:HMDB01859 InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10) InChIKey=RZVAJINKPMORJF-UHFFFAOYSA-N KEGG COMPOUND:103-90-2 KEGG COMPOUND:C06804 KEGG DRUG:D00217 N-(4-hydroxyphenyl)acetamide N-acetyl-p-aminophenol NIST Chemistry WebBook:103-90-2 PDBeChem:TYL Tylenol Wikipedia:Acetaminophen acetaminofen acetaminophene p-Acetylaminophenol p-acetamidophenol p-acetaminophenol p-hydroxyacetanilide p-hydroxyphenolacetamide paracetamol paracetamolum true serotonergic drug roxindole 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol 3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol Jon Ison http://www.ebi.ac.uk/efo/EFO_0003188 roxindole hydrochloride Beilstein:5855538 "Beilstein Registry Number" 3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol ChemIDplus:112192-04-8 "CAS Registry Number" "A ring assembly that has formula C23H26N2O." [] 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol 3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. CHEBI:48561 Jon Ison dopamine antagonist dopamine blocker dopamine receptor antagonist dopaminergic antagonists http://www.ebi.ac.uk/efo/EFO_0001879 James Malone phosphatidylcholine 1,2-Diacyl-sn-glycero-3-phosphocholine 3-sn-Phosphatidylcholine C10H19NO8PR2 C[N+](C)(C)CCOP(O)(=O)OCC(COC([*])=O)OC([*])=O ChemIDplus:8002-43-5 Choline phosphatide CiteXplore:11306571 CiteXplore:14761824 CiteXplore:16882035 CiteXplore:19843309 CiteXplore:3196084 KEGG COMPOUND:C00157 Lecithol PC Phosphatidyl-N-trimethylethanolamine Phospholutein phosphatidylcholine phosphatidylcholines true iron(III) dicitrate Fe(III)dicitrate Iron(III)dicitrate http://www.ebi.ac.uk/efo/EFO_0003205 iron(III) citrate Fe(III)dicitrate CiteXplore:11872840 "PubMed citation" "The complex formed between iron(III) and citrate." [] Iron(III)dicitrate Iron(III)dicitrate Fe(III)dicitrate fenofibrate 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester FNF Fenofibrate Finofibrate Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate Jon Ison Lipantil (TN) Procetofen Tricor (TN) fenofibric acid http://www.ebi.ac.uk/efo/EFO_0003228 Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate Patent:US4058552 "Patent" 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester DrugBank:DB01039 "DrugBank" Patent:DE2250327 "Patent" KEGG DRUG:D00565 "KEGG DRUG" FNF KEGG COMPOUND:C07586 "KEGG COMPOUND" "A chlorobenzophenone that has formula C20H21ClO4." [] Finofibrate KEGG COMPOUND:49562-28-9 "CAS Registry Number" Wikipedia:Fenofibrate "Wikipedia" Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate Procetofen Fenofibrate ChemIDplus:49562-28-9 "CAS Registry Number" Lipantil (TN) Tricor (TN) Finofibrate Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate Fenofibrate Procetofen 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate Lipantil (TN) Tricor (TN) FNF fenoldopam Jon Ison fenoldopam hydrochloride http://www.ebi.ac.uk/efo/EFO_0003180 KEGG COMPOUND:C07693 "KEGG COMPOUND" Patent:DE2751258 "Patent" "A benzazepine that has formula C16H16ClNO3." [] ChemIDplus:67227-56-9 "CAS Registry Number" DrugBank:DB00800 "DrugBank" Wikipedia:Fenoldopam "Wikipedia" Patent:US4197297 "Patent" prodrug topoisomerase I inhibitor An inhibitor of bacterial enzymes of the DNA topoisomerases, Type I class that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. CHEBI:50276 James Malone http://www.ebi.ac.uk/efo/EFO_0001886 topoisomerase I inhibitors Jon Ison parasympatholytic vasoconstrictor agent Drug used to cause constriction of the blood vessels. aromatase inhibitor aromatase inhibitors true antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centers (the vomiting center and the chemoreceptive trigger zone) or affect the peripheral receptors. CHEBI:50919 James Malone antiemetico antiemetics http://www.ebi.ac.uk/efo/EFO_0001857 Jon Ison flucloxacillin (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin 6beta-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido]-2,2-dimethylpenam-3alpha-carboxylic acid Beilstein:4771988 C19H17ClFN3O5S ChemIDplus:5250-39-5 CiteXplore:12569987 DrugBank:DB00301 Floxacillin Floxapen Flucloxacillin InChI=1S/C19H17ClFN3O5S/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28)/t13-,14+,17-/m1/s1 InChIKey=UIOFUWFRIANQPC-JKIFEVAISA-N KEGG COMPOUND:5250-39-5 KEGG COMPOUND:C11748 KEGG DRUG:D04196 Reaxys:4771988 [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(C)onc1-c1c(F)cccc1Cl)C(O)=O flucloxacilina flucloxacillin flucloxacilline flucloxacillinum true dopamine agonist A drug that binds to and activates dopamine receptors. Dani Welter fluoxetine (+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine (+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine Jon Ison fluoxetine hydrochloride http://www.ebi.ac.uk/efo/EFO_0003173 ChemIDplus:54910-89-3 "CAS Registry Number" "A benzenoid aromatic compound that has formula C17H18F3NO." [] KEGG DRUG:54910-89-3 "CAS Registry Number" Patent:US4314081 "Patent" Wikipedia:Fluoxetine "Wikipedia" DrugBank:DB00472 "DrugBank" (+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine (+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine Beilstein:39914106 "Beilstein Registry Number" Patent:DE2500110 "Patent" KEGG DRUG:D00326 "KEGG DRUG" (+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine (+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine acenocoumarol 3-(alpha-(4'-Nitrophenyl)-beta-acetylethyl)-4-hydroxycoumarin 3-(alpha-(p-Nitrophenol)-beta-acetylethyl)-4-hydroxycoumarin 3-(alpha-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin 3-(alpha-Acetonyl-p-nitrobenzyl)-4-hydroxycoumarin 3-(alpha-p-Nitrophenyl-beta-acetylethyl)-4-hydroxycoumarin 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one Acenocoumarin Acenocumarolo Acenokumarin Beilstein:1269370 C19H15NO6 CC(=O)CC(c1ccc(cc1)[N+]([O-])=O)c1c(O)c2ccccc2oc1=O ChEMBL:17275317 ChemIDplus:152-72-7 DrugBank:152-72-7 DrugBank:DB01418 InChI=1S/C19H15NO6/c1-11(21)10-15(12-6-8-13(9-7-12)20(24)25)17-18(22)14-4-2-3-5-16(14)26-19(17)23/h2-9,15,22H,10H2,1H3 InChIKey=VABCILAOYCMVPS-UHFFFAOYSA-N KEGG DRUG:152-72-7 KEGG DRUG:D07064 NIST Chemistry WebBook:152-72-7 Nicoumalone Nicumalon Nitrophenylacetylethyl-4-hydroxycoumarine Nitrovarfarian Nitrowarfarin Patent:US2648682 acenocoumarol acenocoumarolum true antispasmodic (+)-catechin monohydrate (-)-catechin hydrate (2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol monohydrate Catechin hydrate http://www.ebi.ac.uk/efo/EFO_0003227 Catechin hydrate "The monohydrate of (+)-catechin." [] CiteXplore:10651166 "PubMed citation" (2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol monohydrate ChemIDplus:88191-48-4 "CAS Registry Number" (2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol monohydrate Catechin hydrate DNA synthesis inhibitor scopolamine methobromide (-)-(1S,3s,5R,6R,7S)-6,7-epoxy-8-methyl-3-[(S)-tropoyloxy]tropanium bromide (-)-scopolamine methobromide (-)-scopolamine methyl bromide (S)-6beta,7beta-epoxy-8-methyl-3alpha-(-)-tropoyloxy-1alphaH,5alphaH-tromanium bromide Jon Ison N-methylhyoscine bromide N-methylscopolammonium bromide http://www.ebi.ac.uk/efo/EFO_0003258 hyoscine methyl bromide methscopolamine bromide methylscopolamine bromide scopolamine methyl bromide (S)-6beta,7beta-epoxy-8-methyl-3alpha-(-)-tropoyloxy-1alphaH,5alphaH-tromanium bromide (-)-scopolamine methyl bromide N-methylscopolammonium bromide DrugBank:DB00747 "DrugBank" ChemIDplus:155-41-9 "CAS Registry Number" methscopolamine bromide (-)-(1S,3s,5R,6R,7S)-6,7-epoxy-8-methyl-3-[(S)-tropoyloxy]tropanium bromide Reaxys:8173227 "Reaxys Registry Number" methylscopolamine bromide KEGG DRUG:D00715 "KEGG DRUG" DrugBank:DB00462 "DrugBank" Patent:US2753288 "Patent" (-)-scopolamine methobromide KEGG DRUG:155-41-9 "CAS Registry Number" N-methylhyoscine bromide hyoscine methyl bromide scopolamine methyl bromide "A quaternary ammonium salt resulting from the reaction of the amino group of scopolamine with methyl bromide." [] methscopolamine bromide N-methylscopolammonium bromide hyoscine methyl bromide (-)-scopolamine methyl bromide methylscopolamine bromide (-)-scopolamine methobromide (-)-(1S,3s,5R,6R,7S)-6,7-epoxy-8-methyl-3-[(S)-tropoyloxy]tropanium bromide N-methylhyoscine bromide (S)-6beta,7beta-epoxy-8-methyl-3alpha-(-)-tropoyloxy-1alphaH,5alphaH-tromanium bromide scopolamine methyl bromide ammonium sulfate (NH4)2SO4 Jon Ison ammonium sulfate (2:1) ammonium sulphate diammonium sulfate http://www.ebi.ac.uk/efo/EFO_0003218 mascagnite sulfuric acid ammonium salt (1:2) sulfuric acid, diammonium salt mascagnite Reaxys:11343144 "Reaxys Registry Number" KEGG DRUG:7783-20-2 "CAS Registry Number" MetaCyc:NH42SO4 "MetaCyc" sulfuric acid ammonium salt (1:2) ammonium sulphate (NH4)2SO4 CiteXplore:20556652 "PubMed citation" ammonium sulfate (2:1) ChemIDplus:7783-20-2 "CAS Registry Number" diammonium sulfate KEGG DRUG:D08853 "KEGG DRUG" Wikipedia:Ammonium_sulfate "Wikipedia" "An inorganic sulfate salt obtained by reaction of sulfuric acid with two equivalents of ammonia. A high-melting (decomposes above 280degreeC) white solid which is very soluble in water (70.6 g/100 g water at 0degreeC; 103.8 g/100 g water at 100degreeC), it is widely used as a fertilizer for alkaline soils." [] sulfuric acid, diammonium salt sulfuric acid, diammonium salt (NH4)2SO4 ammonium sulphate diammonium sulfate sulfuric acid ammonium salt (1:2) mascagnite ammonium sulfate (2:1) ammonium phosphate Ammonium acid phosphate Ammonium biphosphate Ammonium diacid phosphate Ammonium dihydrogen orthophosphate Ammonium dihydrophosphate Ammonium monobasic phosphate Ammonium monophosphate Ammonium orthophosphate dihydrogen Dihydrogen ammonium phosphate Jon Ison Monoammonium acid phosphate Monoammonium dihydrogen orthophosphate Monoammonium dihydrogen phosphate Monoammonium hydrogen phosphate Monoammonium orthophosphate Monoammonium phosphate Monobasic ammonium phosphate Phosphoric acid, monoammonium salt Primary ammonium phosphate ammonium dihydrogen phosphate http://www.ebi.ac.uk/efo/EFO_0003240 monoammonium phosphate Ammonium dihydrogen orthophosphate Monoammonium acid phosphate Ammonium acid phosphate Primary ammonium phosphate Ammonium monobasic phosphate Monoammonium hydrogen phosphate Ammonium diacid phosphate CiteXplore:18585075 "PubMed citation" ChemIDplus:7722-76-1 "CAS Registry Number" monoammonium phosphate CiteXplore:20338805 "PubMed citation" Monoammonium phosphate Phosphoric acid, monoammonium salt Monobasic ammonium phosphate Monoammonium dihydrogen orthophosphate Ammonium orthophosphate dihydrogen Ammonium biphosphate Ammonium dihydrophosphate Ammonium monophosphate Dihydrogen ammonium phosphate "The ammonium salt of phosphoric acid (molar ratio 1:1)." [] Reaxys:11461082 "Reaxys Registry Number" Monoammonium dihydrogen phosphate Monoammonium orthophosphate Ammonium diacid phosphate Ammonium dihydrogen orthophosphate Monoammonium dihydrogen orthophosphate Ammonium dihydrophosphate Ammonium biphosphate Monobasic ammonium phosphate Ammonium orthophosphate dihydrogen Monoammonium dihydrogen phosphate Ammonium monophosphate Primary ammonium phosphate Monoammonium phosphate Ammonium acid phosphate monoammonium phosphate Monoammonium hydrogen phosphate Monoammonium orthophosphate Phosphoric acid, monoammonium salt Monoammonium acid phosphate Dihydrogen ammonium phosphate Ammonium monobasic phosphate ammonium nitrate Ammonium nitricum Ammonium saltpeter Ammonium(I) nitrate (1:1) Jon Ison Nitrate d'ammonium Nitrate of ammonia Nitrato amonico Nitric acid ammonium salt (1:1) Nitric acid, ammonium salt Norway saltpeter http://www.ebi.ac.uk/efo/EFO_0003185 Ammonium(I) nitrate (1:1) Ammonium nitricum Ammonium saltpeter Nitrato amonico Reaxys:13203931 "Reaxys Registry Number" Nitric acid, ammonium salt "The ammonium salt of nitric acid." [] Wikipedia:Ammonium_nitrate "Wikipedia" Nitrate of ammonia ChemIDplus:6484-52-2 "CAS Registry Number" Norway saltpeter Nitric acid ammonium salt (1:1) Nitrate d'ammonium Nitric acid ammonium salt (1:1) Nitric acid, ammonium salt Nitrate of ammonia Ammonium nitricum Ammonium(I) nitrate (1:1) Ammonium saltpeter Nitrate d'ammonium Nitrato amonico Norway saltpeter caesium chloride Cesium monochloride Jon Ison Tricesium trichloride caesium monochloride caesium(I) chloride cesium chloride cesium(I) chloride http://www.ebi.ac.uk/efo/EFO_0003181 Wikipedia:Cesium_chloride "Wikipedia" Cesium monochloride Tricesium trichloride Reaxys:3534981 "Reaxys Registry Number" CiteXplore:698485 "PubMed citation" "The inorganic chloride salt of caesium; each caesium ion is coordinated by eight chlorine ions." [] cesium chloride ChemIDplus:7647-17-8 "CAS Registry Number" cesium(I) chloride caesium(I) chloride NIST Chemistry WebBook:7647-17-8 "CAS Registry Number" caesium monochloride CiteXplore:11058836 "PubMed citation" caesium monochloride Tricesium trichloride Cesium monochloride caesium(I) chloride cesium chloride cesium(I) chloride phase-transfer catalyst explosive fludarabine phosphate 2-Fluoro-ARA AMP 2-Fluoroadenine arabinoside 5'-monophosphate 2F-ara-AMP 9-beta-Arabinofuranosyl-2-fluoroadenine-5'-phosphate 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-(dihydrogen phosphate) 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-monophosphate FAMP Fludarabine 5'-monophosphate Fludarabine monophosphate Jon Ison fludarabine http://www.ebi.ac.uk/efo/EFO_0003216 CiteXplore:20686506 "PubMed citation" ChemIDplus:75607-67-9 "CAS Registry Number" CiteXplore:19283354 "PubMed citation" DrugBank:DB01073 "DrugBank" CiteXplore:21736869 "PubMed citation" CHEBI:31616 Patent:WO2010046917 "Patent" Fludarabine monophosphate CiteXplore:21725721 "PubMed citation" 2-Fluoroadenine arabinoside 5'-monophosphate CiteXplore:19567212 "PubMed citation" 9-beta-Arabinofuranosyl-2-fluoroadenine-5'-phosphate FAMP Wikipedia:Fludarabine "Wikipedia" 2-Fluoro-ARA AMP CiteXplore:20514405 "PubMed citation" CiteXplore:19862681 "PubMed citation" CiteXplore:21296675 "PubMed citation" 2F-ara-AMP 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-(dihydrogen phosphate) CiteXplore:20215092 "PubMed citation" CiteXplore:21909959 "PubMed citation" "A purine arabinonucleoside monophosphate having 2-fluoroadenine as the nucleobase. Antiviral agent; once incorporated into DNA, 2F-ara-ATP (its metabolite) functions as a DNA chain terminator" [] CiteXplore:20467451 "PubMed citation" Patent:WO2010133629 "Patent" KEGG DRUG:D01907 "KEGG DRUG" 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-monophosphate Reaxys:8167686 "Reaxys Registry Number" Fludarabine 5'-monophosphate CiteXplore:19915381 "PubMed citation" KEGG DRUG:75607-67-9 "CAS Registry Number" FAMP 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-(dihydrogen phosphate) Fludarabine monophosphate 2-Fluoro-ARA AMP 2-Fluoroadenine arabinoside 5'-monophosphate 9-beta-Arabinofuranosyl-2-fluoroadenine-5'-phosphate Fludarabine 5'-monophosphate 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-monophosphate 2F-ara-AMP mefloquine Jon Ison Racemic mefloquine [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [DL-erythro-alpha-2-Piperidyl-2,8-bis(trifluoromethyl)]-4-quinolinemethanol http://www.ebi.ac.uk/efo/EFO_0003288 [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol Reaxys:5306591 "Reaxys Registry Number" KEGG DRUG:D04895 "KEGG DRUG" CiteXplore:21118921 "PubMed citation" Wikipedia:Mefloquine "Wikipedia" CiteXplore:21861987 "PubMed citation" CHEBI:6718 DrugBank:DB00358 "DrugBank" CiteXplore:22233563 "PubMed citation" "A racemate composed of (+)-(11R,2'S)- and (-)-(11S,2'R)-enantiomers of mefloquine. An antimalarial agent which acts as a blood schizonticide; its mechanism of action is unknown." [] KEGG COMPOUND:C07633 "KEGG COMPOUND" CiteXplore:22245668 "PubMed citation" [DL-erythro-alpha-2-Piperidyl-2,8-bis(trifluoromethyl)]-4-quinolinemethanol CiteXplore:22232280 "PubMed citation" ChemIDplus:53230-10-7 "CAS Registry Number" KEGG COMPOUND:53230-10-7 "CAS Registry Number" CiteXplore:22246492 "PubMed citation" CiteXplore:22223333 "PubMed citation" CiteXplore:22236373 "PubMed citation" Racemic mefloquine CiteXplore:22217970 "PubMed citation" CiteXplore:22006004 "PubMed citation" CiteXplore:21853223 "PubMed citation" [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol Racemic mefloquine [DL-erythro-alpha-2-Piperidyl-2,8-bis(trifluoromethyl)]-4-quinolinemethanol nevirapine 11-cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one C15H14N4O Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12 ChemIDplus:129618-40-2 CiteXplore:1712395 DrugBank:DB00238 InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20) InChIKey=NQDJXKOVJZTUJA-UHFFFAOYSA-N KEGG COMPOUND:129618-40-2 KEGG COMPOUND:C07263 KEGG DRUG:D00435 NEV NVP Nevirapine Reaxys:4757598 Viramune Wikipedia:Nevirapine nevirapine true topotecan 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecin Jon Ison Topotecan http://www.ebi.ac.uk/efo/EFO_0003177 CiteXplore:21255983 "PubMed citation" KEGG COMPOUND:123948-87-8 "CAS Registry Number" CiteXplore:22190039 "PubMed citation" CiteXplore:22028494 "PubMed citation" CiteXplore:21352915 "PubMed citation" CiteXplore:21910214 "PubMed citation" Topotecan Reaxys:4279441 "Reaxys Registry Number" CiteXplore:20574789 "PubMed citation" "A pyranoindolizinoquinoline used as an antineoplastic agent. It is a derivative of camptothecin and works by binding to the topoisomerase I-DNA complex and preventing religation of these 328 single strand breaks." [] CiteXplore:22136714 "PubMed citation" CiteXplore:22075006 "PubMed citation" ChemIDplus:123948-87-8 "CAS Registry Number" Wikipedia:Topotecan "Wikipedia" KEGG DRUG:D08618 "KEGG DRUG" CHEBI:9634 KEGG COMPOUND:C11158 "KEGG COMPOUND" 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecin DrugBank:DB01030 "DrugBank" Patent:EP321122 "Patent" Topotecan 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecin metformin 1,1-Dimethylbiguanide C4H11N5 CN(C)C(=N)NC(N)=N ChemIDplus:657-24-9 InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8) InChIKey=XZWYZXLIPXDOLR-UHFFFAOYSA-N KEGG COMPOUND:657-24-9 KEGG COMPOUND:C07151 Metformin N,N-dimethylimidodicarbonimidic diamide Wikipedia:Metformin true myoglobin COMe:PRX000322 KEGG COMPOUND:C05782 Myoglobin true vertebrate myoglobin perphenazine 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol 2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol Beilstein:54730 C21H26ClN3OS ChemIDplus:58-39-9 Chlorpiprazine CiteXplore:1650428 DrugBank:DB00850 InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 InChIKey=RGCVKNLCSQQDEP-UHFFFAOYSA-N KEGG COMPOUND:58-39-9 KEGG COMPOUND:C07427 KEGG DRUG:D00503 NIST Chemistry WebBook:58-39-9 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 Patent:US2766235 Patent:US2860138 Perfenazine Perphenazin Perphenazine Trilafon Wikipedia:Perphenazine gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine perfenazina perphenazine perphenazinum true risperidone 3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one Beilstein:4891881 C23H27FN4O2 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 ChemIDplus:106266-06-2 DrugBank:DB00734 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 InChIKey=RAPZEAPATHNIPO-UHFFFAOYSA-N KEGG DRUG:106266-06-2 KEGG DRUG:D00426 Patent:EP196132 Patent:US4804663 Risperdal Risperin Rispolept Rispolin Sequinan Wikipedia:Risperidone risperidona risperidone risperidonum true ticlopidine 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine C14H14ClNS ChemIDplus:55142-85-3 Clc1ccccc1CN1CCc2sccc2C1 DrugBank:DB00208 InChI=1S/C14H14ClNS/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14/h1-4,6,8H,5,7,9-10H2 InChIKey=PHWBOXQYWZNQIN-UHFFFAOYSA-N KEGG COMPOUND:C07140 Patent:DE2404308 Patent:US4051141 Patent:US4127580 Wikipedia:Ticlopidine ticlopidina ticlopidine ticlopidinum true verapamil Jon Ison Verapamil dexverapamil http://www.ebi.ac.uk/efo/EFO_0003197 KEGG COMPOUND:52-53-9 "CAS Registry Number" KEGG COMPOUND:C07188 "KEGG COMPOUND" Beilstein:2825000 "Beilstein Registry Number" DrugBank:DB00661 "DrugBank" ChemIDplus:52-53-9 "CAS Registry Number" "An L-type calcium channel blocker of the phenylalkylamine class." [] Verapamil KEGG DRUG:D02356 "KEGG DRUG" Verapamil cellular component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together. label A label is a symbol that is part of some other datum and is used to either partially define the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label. IAO Group data item Data is an information entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements. IAO information entity An information entity is an entity that represents information about some other entity. For example, a measurement, a clustered data set. James Malone an information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity http://www.ebi.ac.uk/efo/EFO_0001435 information information content entity true data format specification Alan Ruttenberg A data format specification is the information content borne by the document published defining the specification. Example: The ISO document specifying what encompasses an XML document; The instructions in a XSD file data set A data set is an information entity that is an aggregate of other information entities that have something in common and are considered to form a unit. James Malone http://www.ebi.ac.uk/efo/EFO_0001445 image An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface. OBI material supplier role Jennifer Fostel biosource provider The role of a person or organisation in supplying materials such as animal subjects, reagents or other materials used in an investigation. James Malone (modified from original) mass spectrometer A mass spectrometer is an instrument which is used to measure the mass to charge ratio of ions. All mass spectrometers consist of three basic parts: an ion source, a mass analyzer, and a detector system. The stages within the mass spectrometer are: 1. Production of ions from the sample 2. Separation of ions with different masses 3. Detection of the number of ions of each mass produced 4.Collection of data to generate the mass spectrum http://www.ebi.ac.uk/efo/EFO_0002700 A mass spectrometer is an instrument which is used to measure the mass to charge ratio of ions. All mass spectrometers consist of three basic parts: an ion source, a mass analyzer, and a detector system. The stages within the mass spectrometer are: 1. Production of ions from the sample 2. Separation of ions with different masses 3. Detection of the number of ions of each mass produced 4.Collection of data to generate the mass spectrum assay A hybridization on a microarray. A planned process with the objective to produce information about some evaluant An assay is a process with the objective to create as an output information about a material entity (bearing evaluant role). James Malone OBI_0000070 http://www.ebi.ac.uk/efo/EFO_0001455 A planned process with the objective to produce information about some evaluant measuring scientific observation quantitative confidence value A data item which is used to indicate the degree of uncertainty about a measurement. OBI gene list A gene list is a report of the names or identifiers of genes that are the outcome of an analysis or have been put together for the purpose of an analysis. Chris Stoeckert A gene list is a report of the names or identifiers of genes that are the outcome of an analysis or have been put together for the purpose of an analysis. population A population is a group of material entities consisting of individuals which share a particular characteristic such as inhabiting a particular region or area or ability to interbreed. James Malone modified from original OBI definition NIFSTD:sao2254405550 Tomasz Adamusiak modified from original OBI definition http://www.ebi.ac.uk/efo/EFO_0000664 true organization An organization is a continuant entity which can play roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members. James Malone Jie Zheng MO_177 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002010 organisation An organization is a continuant entity which can play roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members. protocol A protocol is an information entity which is a set of instructions that describe an how an experiment is done. James Malone Jie Zheng MO_214 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001442 plan specification true a protocol is a plan specification which has sufficient level of detail and quantitative information to communicate it between domain experts, so that different domain experts will reliably be able to independently reproduce the process. analyte Analyte role is a role borne by a material entity and realized by implementation of an analyte measuring assay with objective to detect the magnitude/concentration/ amount of the analyte in the entity bearing evaluant role. James Malone analyte role http://www.ebi.ac.uk/efo/EFO_0001452 Analyte role is a role borne by a molecular entity and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role PCR OBI Consortium PCR is the process in which a DNA polymerase is used to amplify a piece of DNA by in vitro enzymatic replication. As PCR progresses, the DNA thus generated is itself used as a template for replication. This sets in motion a chain reaction in which the DNA template is exponentially amplified. polymerase chain reaction reverse transcription PCR Reverse transcription PCR is a process which allow amplification of cDNA during a pcr reaction while the cDNA results from a retrotranscription of messenger RNA isolated from a material entity. RT-PCR reverse transcription polymerase chain reaction OBI Consortium material sample A material which is collected with the intention of being representative of a greater whole (i.e. a sample). blood drawn from patient to measure his systemic glucose level. A population of humans with HIV enrolled in a study taken to represent patients with HIV in general. sample population labeled specimen A specimen that has been modified in order to be able to detect it in future experiments. spike-in quality control role A reference substance role that is borne by a material entity with a known amount which is mixed into the evaluant of assays for quality control or data normalization purposes. Chris Stoeckert, Jie Zheng, Bjoern Peters dye swap quality control role A reference substance role that is borne by a material entity used in a dye swap design experiment for quality control or data normalization purposes Jie Zheng Chris Stoeckert validation by reverse transcription PCR design A study design in which checks the accuracy or the quality of the result of an assay by comparing with reverse transcription PCR results. Chris Stoeckert Jie Zheng validation by real time PCR design A study design in which the accuracy or the quality of the result of an assay is checked by comparing with real time PCR results. Jie Zheng Chris Stoeckert p-value A quantitative confidence value that measures the minimum false discovery rate that is incurred when calling that test significant. Adapted from several sources, including http://.en/wikipedia.org/wiki/False_discovery_rate http://svitsrv25.epfl.ch/R-doc/library/qvalue.html specimen with known storage state A specimen for which it is known whether it has been subjected to storage of a specified type. Chris Stoeckert, Jie Zheng biosource type organism A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. E.g Drosophila melanogaster Drosophila melanogaster James Malone Jie Zheng MO_508 NIFSTD:birnlex_376 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#organism http://www.ebi.ac.uk/efo/EFO_0000634 true species A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. specimen James Malone Philippe Rocca-Serra A material which is obtained and stored for potential use during an investigation. data transformation A data transformation is a process which produces output data from input data A data transformation is a process which produces output data from input data - e.g. the application of a clustering protocol to microarray data or the application of a statistical testing method on a primary data set to determine a p-value. James Malone OBI_0200000 http://www.ebi.ac.uk/efo/EFO_0000393 A data transformation is a process which produces output data from input data data analysis data processing biexponential transformation James Malone http://www.ebi.ac.uk/efo/EFO_0002031 A biexponential transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation B(y)-x=0, where B denotes a b transformation. loess transformation James Malone http://www.ebi.ac.uk/efo/EFO_0002093 A loess transformation is a data transformation that takes as input a collection of real number pairs (x, y) and, after performing (one or more) loess fittings, utilizes the resulting curves to transform each (x, y) in the input into (x, y-f(x)) where f(x) is one of the fitted curves. normalization data transformation James Malone http://www.ebi.ac.uk/efo/EFO_0002030 A normalization data transformation is a data transformation that has objective normalization. nucleic acid hybridization A process by which totally or partially complementary, single-stranded nucleic acids are combined into a single molecule called heteroduplex or homoduplex to an extent depending on the amount of complementarity. a planned process by which totally or partially complementary, single-stranded nucleic acids are combined into a single molecule called heteroduplex or homoduplex to an extent depending on the amount of complementarity. a planned process by which totally or partially complementary, single-stranded nucleic acids are combined into a single molecule called heteroduplex or homoduplex to an extent depending on the amount of complementarity. DNA sequencer A DNA sequencer is an instrument that determines the order of deoxynucleotides in deoxyribonucleic acid sequences. DNA_sequencer DNA_sequencer[accessedResource: MO_676][accessDate: 05-04-2011] James Malone MO_676 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#DNA_sequencer http://www.ebi.ac.uk/efo/EFO_0002015 A DNA sequencer is an instrument that determines the order of deoxynucleotides in deoxyribonucleic acid sequences. array scanner James Malone MO_824 array_scanner array_scanner[accessedResource: MO_824][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#array_scanner http://www.ebi.ac.uk/efo/EFO_0002014 An processed material which acquires images of fluorescence (induced with lasers) from labeled molecules on the surface of the microarray chip arrayer An arrayer is an instrument which deposits biological material onto a substrate in a defined pattern. James Malone MO_697 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#arrayer http://www.ebi.ac.uk/efo/EFO_0002016 a device which deposits biological material onto a substrate in a defined pattern. centrifuge A centrifuge is an instrument, generally driven by a motor, that puts an object in rotation around a fixed axis, applying force perpendicular to the axis. The centrifuge works using the sedimentation principle, where the centripetal acceleration is used to separate substances of greater and lesser density. James Malone MO_476 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#centrifuge http://www.ebi.ac.uk/efo/EFO_0002013 computer A computer is an instrument which manipulates (stores, retrieves, and processes) data according to a list of instructions. James Malone MO_510 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#computer http://www.ebi.ac.uk/efo/EFO_0002088 A computer is an instrument which manipulates (stores, retrieves, and processes) data according to a list of instructions. heating block A heating block is an instrument or part of an instrument which raises or maintains the temperature of a sample to a defined constant temperature during certain parts of an assay James Malone MO_663 heating_block heating_block[accessedResource: MO_663][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#heating_block http://www.ebi.ac.uk/efo/EFO_0002017 A heating block is an instrument or part of an instrument which raises or maintains the temperature of a sample to a defined constant temperature during certain parts of an assay homogenizer James Malone MO_714 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#homogenizer http://www.ebi.ac.uk/efo/EFO_0002018 A homogenizer is an instrument for the homogenization of various types of material, such as tissue, plant, food, soil, and many others. hybridization chamber A container which is used to maintain constant contact of a liquid on an array. This can be either a glass vial or slide. James Malone MO_563 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#hybridization_chamber http://www.ebi.ac.uk/efo/EFO_0002019 hybridization_chamber hybridization_chamber[accessedResource: MO_563][accessDate: 05-04-2011] A device which is used to maintain constant contact of a liquid on an array. This can be either a glass vial or slide. hybridization station An instrument which is used to maintain the temperature of one or more hybridization_chamber(s) at a defined, constant temperature. James Malone MO_497 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#hybridization_station http://www.ebi.ac.uk/efo/EFO_0002020 hybridization_station hybridization_station[accessedResource: MO_497][accessDate: 05-04-2011] A device which is used to maintain the temperature of one or more hybridization_chamber(s) at a defined, constant temperature. liquid handler A liquid_handler is an instrument used for automated liquid transfer and handling. James Malone MO_868 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#liquid_handler http://www.ebi.ac.uk/efo/EFO_0002021 liquid_handler liquid_handler[accessedResource: MO_868][accessDate: 05-04-2011] a device that is used for automated liquid transfer and handling. liquid_handling_instrument oligonucleotide synthesizer An instrument used to chemically synthesize oligonucleotides. James Malone MO_930 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#oligo_synthesizer http://www.ebi.ac.uk/efo/EFO_0002022 oligo_synthesizer oligo_synthesizer[accessedResource: MO_930][accessDate: 05-04-2011] An instrument used to chemically synthesize oligonucleotides. sonicator A sonicator is an instrument that converts a variable electrical current to mechanical vibration of a metalic probe. The instrument is used for the lysis of cells, the mixing of compounds or solutions, or to create emulsions. [accessedResource: http://purl.obolibrary.org/obo/OBI_0400114][accessDate: 2009-08-12] James Malone MO_477 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#sonicator http://www.ebi.ac.uk/efo/EFO_0002023 An instrument that converts a variable electrical current to mechanical vibration of a metallic probe. The instrument is used for the lysis of cells, the mixing of compounds or solutions, or to create emulsions. spectrophotometer James Malone MO_716 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#spectrophotometer http://www.ebi.ac.uk/efo/EFO_0002024 A spectrophotometer is an instrument that measures the intensity of light as a function of the color, or more specifically, the wavelength of light, transmitted by a substance. thermal cycler James Malone MO_854 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#thermal_cycler http://www.ebi.ac.uk/efo/EFO_0002025 thermal_cycler thermal_cycler[accessedResource: MO_854][accessDate: 05-04-2011] An instrument that is capable of repeatedly altering and maintaining specific temperatures for defined periods of time. DNA_amplifier PCR_machine Polymerase_Chain_Reaction_ machine thermocycler vacuum dryer An instrument which removes liquid by the application of negative pressure, i.e. vacuum. James Malone MO_696 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#vacuum_dryer http://www.ebi.ac.uk/efo/EFO_0002026 vacuum_dryer vacuum_dryer[accessedResource: MO_696][accessDate: 05-04-2011] An instrument which removes liquid by the application of negative pressure, i.e. vacuum. vortexer James Malone Jie Zheng MO_983 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#vortexer http://www.ebi.ac.uk/efo/EFO_0002027 A vortexer is an instrument that mixes small vials of liquid by creating a rotation of the liquid around its own center. It consists of an electric motor with the drive shaft oriented vertically and attached to a cupped rubber piece mounted slightly off-center. As the motor runs the rubber piece oscillates rapidly in a circular motion. When a test tube or other appropriate container is pressed into the rubber cup (or touched to its edge) the motion is transmitted to the liquid inside and a vortex is created. vortex_mixer water bath James Malone MO_541 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#waterbath http://www.ebi.ac.uk/efo/EFO_0002089 waterbath waterbath[accessedResource: MO_541][accessDate: 05-04-2011] A water bath is a temperature control bath in which a water acts as contact medium enabling temperature transfer from the heating element or cooling element to the sample. The temperature can be controlled in the 0 to 100 degree centigrade range (under normal pressure). tumor grading Determination of the grade (severity/stage) of a tumor sample, used in cancer biology to describe abnormalities/qualities of tumor cells or tissues. Values can be described by terms from NCI Thesaurus. Helen Parkinson and Adam Witney group assignment James Malone, modified from original OBI definition (Philippe Rocca Serra) cohort assignment Group assignment is a process in which an organism is assigned to a particular group or cohort, such as assignment to a treated and control group. study assignment infect The detrimental process in which an infectious agent colonizes or replicates in a host environment IEDB pathological process Abnormal, harmful processes caused by or associated with a disease 6 ripening BBCH principal growth stage 8 silique ripening Arabidopsis Growth principal growth stage 8 Maturation of the fruit. radicle emergence A root development stage during which a radicle emerges from the seed coat. BBCH growth stage 05 4 flowering BBCH principal growth stage 6 The stage at which any flower(s) on the plant are open. sporophyte senescent stage sporophyte senescence stage A sporophyte development stage during which a sporophyte participates in multicellular organism senescence. Arabidopsis Growth principal growth stage 9 seed imbibition stage BBCH growth stage 01 A germination stage during which there is absorption of water by the seed. FL.04 end of flowering Arabidopsis Growth Stage 6.90 flowering complete The stage at which flowering is complete. FL.00 first flower(s) open The stage at which the first flower(s) open. Arabidopsis Growth Stage 5.10 Stage R1 Open flower at any node on the main stem coleoptile emergence stage A sporophyte vegetative stage during which the coleoptile emerges from the seed coat. BBCH growth stage 09 3 inflorescence detectable stage BBCH principal growth stage 4 A reproductive growth stage during which an inflorescence is detectable. This includes the stage when an inflorescence starts to develop (and is detectable only by assay or with a microscope), to the stage where it is visible to the naked eye. This includes the booting stage in the grasses (Poaceae). There is no one-to-one correspondence between some of the phases of inflorescence formation in members of Poaceae (e.g., booting) with that of other families. BBCH principal growth stage 5 0 seed germination stage The resumption of growth by the embryo in a seed. Principal growth stage 0 LP.07 seven leaves visible BBCH growth stage 17 The stage at which leaves at seven nodes, other than the cotyledonary node, are visible above ground. LP.12 twelve leaves visible The stage at which leaves at twelve nodes, other than the cotyledonary node, are visible above ground. LP.05 five leaves visible BBCH growth stage 15 The stage at which leaves at five nodes, other than the cotyledonary node, are visible above ground. LP.17 seventeen leaves visible The stage at which leaves at seventeen nodes, other than the cotyledonary node, are visible above ground. mid rosette growth Rosette has reached approximately 50% of its final diameter. LP.18 eighteen leaves visible The stage at which leaves at eighteen nodes, other than the cotyledonary node, are visible above ground. late rosette growth Rosette has reached approximately 70% of its final diameter. rosette growth complete Stage at which rosette no longer increases in diameter, its leaf growth and expansion having ceased. early rosette growth Rosette has reached approximately 20% of its final diameter. LP.20 twenty or more leaves whorls visible The stage at which leaves at twenty or more nodes, other than the cotyledonary node, are visible above ground. LP.13 thirteen leaves visible The stage at which leaves at thirteen nodes, other than the cotyledonary node, are visible above ground. LP.14 fourteen leaves visible The stage at which leaves at fourteen nodes, other than the cotyledonary node, are visible above ground. LP.01 one leaf visible BBCH growth stage 11 The stage at which leaves at one node, other than the cotyledonary node, are visible above ground. LP.08 eight leaves visible BBCH growth stage 18 The stage at which leaves at eight nodes, other than the cotyledonary node, are visible above ground. LP.02 two leaves visible BBCH growth stage 12 The stage at which leaves at two nodes, other than the cotyledonary node, are visible above ground. LP.09 nine leaves visible BBCH growth stage 19 The stage at which leaves at nine nodes, other than the cotyledonary node, are visible above ground. LP.10 ten leaves visible The stage at which leaves at ten nodes, other than the cotyledonary node, are visible above ground. LP.15 fifteen leaves visible The stage at which leaves at fifteen nodes, other than the cotyledonary node, are visible above ground. LP.03 three leaves visible BBCH growth stage 13 The stage at which leaves at three nodes, other than the cotyledonary node, are visible above ground. 1 main shoot growth stage The stage at which vegetative structures are being produced by SAM. rosette growth Stages of growth based on expansion of the rosette in Arabidopsis. LP.04 four leaves visible BBCH growth stage 14 The stage at which leaves at four nodes, other than the cotyledonary node, are visible above ground. LP.11 eleven leaves visible The stage at which leaves at eleven nodes, other than the cotyledonary node, are visible above ground. LP.16 sixteen leaves visible The stage at which leaves at sixteen nodes, other than the cotyledonary node, are visible above ground. LP.19 nineteen leaves visible The stage at which leaves at nineteen nodes, other than the cotyledonary node, are visible above ground. LP.06 six leaves visible The stage at which leaves at six nodes, other than the cotyledonary node, are visible above ground. BBCH growth stage 16 leaf production The stage at which the leaves produced by SAM are visible above the ground in a seedling or mature plant. coleorhiza emergence stage A root development stage during which a coleorhiza emerges from the seed coat. sporophyte development stage A whole plant development stage that has as primary participant a whole plant during the interval between fertilization (or apogamy) and death. sporophytic phase Arabidopsis developmental stage obsolete_cell line cell 2.15 Ele Holloway James Malone Not used - already a cell line parent class http://www.ebi.ac.uk/efo/EFO_0002477 male germ cell James Malone http://www.ebi.ac.uk/efo/EFO_0000576 testis - germ cell sperm A mature male germ cell that develops from a spermatid. A mature male germ cell that develops from a spermatid.[accessedResource: ZFA:0009006][accessDate: 05-04-2011] A mature, haploid male gamete. A mature, haploid male gamete.[accessedResource: FBbt:00004954][accessDate: 05-04-2011] Definitive germ cell of the male sex. FBbt:00004954 FMAID:67338 James Malone MA:0002765 MAT:0000131 Mature sperm cell[accessedResource: FMAID:67338][accessDate: 05-04-2011] SAEL:93 Spermatozoon[accessedResource: FMAID:67338][accessDate: 05-04-2011] Tomasz Adamusiak WBbt:0005321 ZFA:0009006 http://www.ebi.ac.uk/efo/EFO_0000983 male gamete mature sperm cell semen sperm cell sperm cell[accessedResource: ZFA:0009006][accessDate: 05-04-2011] spermatazoon spermatazoon[accessedResource: MAT:0000131][accessDate: 05-04-2011] spermatozoid spermatozoid[accessedResource: ZFA:0009006][accessDate: 05-04-2011] spermatozoon oocyte A female germ cell that has entered meiosis. A female germ cell that has entered meiosis.[accessedResource: CL:0000023][accessDate: 05-04-2011] Tomasz Adamusiak ZFA:0009008 http://www.ebi.ac.uk/efo/EFO_0002443 plant egg A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization.[accessedResource: CL:0000025][accessDate: 05-04-2011] James Malone MAT:0000213 OntologyMappingImporter following MAT:0000213 PO:0020094 Tomasz Adamusiak egg egg[accessedResource: MAT:0000213][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0001000 mature oocyte mature oocyte[accessedResource: CL:0000025][accessDate: 05-04-2011] ovum ovum[accessedResource: CL:0000025][accessDate: 05-04-2011] stem cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.[accessedResource: CL:0000034][accessDate: 05-04-2011] James Malone http://www.ebi.ac.uk/efo/EFO_0000709 hematopoietic stem cell A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4,CD5,CD8 alpha chain, CD14, CD19, CD20, integrin alpha-M, neural cell adhesion molecule 1, lymphocyte antigen 6G, lymphocyte antigen 76. A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4,CD5,CD8 alpha chain, CD14, CD19, CD20, integrin alpha-M, neural cell adhesion molecule 1, lymphocyte antigen 6G, lymphocyte antigen 76.[accessedResource: CL:0000037][accessDate: 05-04-2011] HSC HSC[accessedResource: CL:0000037][accessDate: 05-04-2011] James Malone Tomasz Adamusiak blood forming stem cell blood forming stem cell[accessedResource: CL:0000037][accessDate: 05-04-2011] colony forming unit hematopoietic hemopoietic stem cell hemopoietic stem cell[accessedResource: CL:0000037][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000527 erythroid progenitor cell A progenitor cell committed to the erythroid lineage. A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative).[accessedResource: CL:0000038][accessDate: 05-04-2011] BFU-E CFU-E Tomasz Adamusiak blast forming unit erythroid burst forming unit erythroid colony forming unit erythroid erythroid stem cell http://www.ebi.ac.uk/efo/EFO_0002434 monoblast mature eosinophil neutrophilic myeloblast mature basophil neuronal stem cell James Malone Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors. Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors.[accessedResource: CL:0000047][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000624 neural stem cell neural stem progenitor cell multipotent stem cell A stem cell that can give rise to mulitple lineages of cells. A stem cell that can give rise to multiple lineages of cells. A stem cell that can give rise to multiple lineages of cells.[accessedResource: CL:0000048][accessDate: 05-04-2011] James Malone Multipotent cell Multipotent cell[accessedResource: CL:0000048][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000608 multi fate stem cell multi fate stem cell[accessedResource: CL:0000048][accessDate: 05-04-2011] multi-fate stem cell multi-fate stem cell[accessedResource: CL:0000048][accessDate: 05-04-2011] multifate stem cell multifate stem cell[accessedResource: CL:0000048][accessDate: 05-04-2011] multipotent adult progenitor cell common myeloid progenitor megakaryocyte-erythroid progenitor cell common lymphoid progenitor blast cell A precursor cell with a limited number of potential fates. A precursor cell with a limited number of potential fates.[accessedResource: CL:0000055][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0003034 non-terminally differentiated cell non-terminally differentiated cell[accessedResource: CL:0000055][accessDate: 05-04-2011] myoblast An embryonic (precursor) cell of the myogenic lineage that develops from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. An embryonic (precursor) cell of the myogenic lineage that develops from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes.[accessedResource: CL:0000056][accessDate: 05-04-2011] An embryonic cell that becomes a cell of muscle fiber. An embryonic cell that becomes a cell of muscle fiber.[accessedResource: BTO:0000222][accessDate: 05-04-2011] BTO:0000222 James Malone http://www.ebi.ac.uk/efo/EFO_0000611 sarcoblast fibroblast A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.[accessedResource: CL:0000057][accessDate: 05-04-2011] A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms. A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms.[accessedResource: BTO:0000452][accessDate: 05-04-2011] A large, flat, oval cell found in connective tissue and responsible for the formation of fibers. A large, flat, oval cell found in connective tissue and responsible for the formation of fibers.[accessedResource: NIFSTD:nlx_cell_20090201][accessDate: 05-04-2011] BTO:0000452 James Malone NIFSTD:nlx_cell_20090201 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000496 mouse embryonic fibroblast primary dermal fibroblast osteoblast A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.[accessedResource: CL:0000062][accessDate: 05-04-2011] James Malone http://www.ebi.ac.uk/efo/EFO_0001375 epithelial cell A cell that is usually found in a two-dimensional sheet with a free surface. A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.[accessedResource: CL:0000066][accessDate: 05-04-2011] BTO:0000414 Cell that cover the surface of the body and line its cavities. Cell that cover the surface of the body and line its cavities.[accessedResource: BTO:0000414][accessDate: 05-04-2011] Cell that line the inner and outer surfaces of the body by forming cellular layers (epithelium) or masses (MSH). Cell that line the inner and outer surfaces of the body by forming cellular layers (epithelium) or masses (MSH).[accessedResource: NIFSTD:sao441624014][accessDate: 05-04-2011] Epitheliocyte Epitheliocyte[accessedResource: CL:0000066][accessDate: 05-04-2011] James Malone NIFSTD:sao441624014 Tomasz Adamusiak epithelial http://www.ebi.ac.uk/efo/EFO_0000475 blood vessel endothelial cell Cuboidal endothelial cell of vascular tree Cuboidal endothelial cell of vascular tree[accessedResource: CL:0000071][accessDate: 05-04-2011] James Malone The endothelial cells that line the vasculature. The endothelial cells that line the vasculature.[accessedResource: CL:0000071][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000297 primary blood vessel endothelial cell primary microvascular endothelial cell umbilical vein endothelial cell mesothelial cell A flattened epithelial cell of mesenchymal origin that lines the serous cavity. A flattened epithelial cell of mesenchymal origin that lines the serous cavity.[accessedResource: CL:0000077][accessDate: 05-04-2011] James Malone Mesotheliocyte Mesotheliocyte[accessedResource: CL:0000077][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0001419 circulating cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. A cell which moves among different tissues of the body, via blood, lymph, or other medium.[accessedResource: CL:0000080][accessDate: 05-04-2011] Ele Holloway James Malone ZFA:0009043 http://www.ebi.ac.uk/efo/EFO_0002478 blood cell A cell found predominately in the blood. A cell found predominately in the blood.[accessedResource: CL:0000081][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002453 exocrine pancreas cell An epithelial cell of the pancreas. An epithelial cell of the pancreas.[accessedResource: CL:0000083][accessDate: 05-04-2011] BTO:0000028 Cells of the pancreas that secrete digestive enzymes, the archetypal secretory cell upon which much of the early work on the sequence of events in the secretory process was done. Cells of the pancreas that secrete digestive enzymes, the archetypal secretory cell upon which much of the early work on the sequence of events in the secretory process was done.[accessedResource: BTO:0000028][accessDate: 05-04-2011] Jie Zheng Tomasz Adamusiak epithelial cell of exocrine pancreas epithelial cell of pancreas epithelial cell of pancreas[accessedResource: CL:0000083][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002541 pancreatic acinar cell pancreatic acinar cell[accessedResource: BTO:0000028][accessDate: 05-04-2011] pancreatic acinus T cell A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.[accessedResource: CL:0000084][accessDate: 05-04-2011] James Malone MSH:D013601 T lymphocyte T lymphocyte[accessedResource: CL:0000084][accessDate: 05-04-2011] T-cell T-cell[accessedResource: CL:0000084][accessDate: 05-04-2011] T-lymphocyte T-lymphocyte[accessedResource: CL:0000084][accessDate: 05-04-2011] T-lymphocytes Th1 Th2 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000208 immature T cell mature T cell pancreatic T effector cell true Kupffer cell osteoclast granulocyte A leukocyte with abundant granules in the cytoplasm. A leukocyte with abundant granules in the cytoplasm.[accessedResource: CL:0000094][accessDate: 05-04-2011] A polymorphonuclear white blood cell with granule-containing cytoplasm. A polymorphonuclear white blood cell with granule-containing cytoplasm.nIn humans the granulocytes are also classified as polymorphonuclear leucocytes and are subdivided according to the staining properties of the granules into eosinophils, basophils and neutrophils, some invertebrate blood cells are also referred to, not very helpfully, as granulocytes. A polymorphonuclear white blood cell with granule-containing cytoplasm.nIn humans the granulocytes are also classified as polymorphonuclear leucocytes and are subdivided according to the staining properties of the granules into eosinophils, basophils and neutrophils, some invertebrate blood cells are also referred to, not very helpfully, as granulocytes.[accessedResource: BTO:0000539][accessDate: 05-04-2011] BTO:0000539 Granular leucocyte Granular leucocyte[accessedResource: CL:0000094][accessDate: 05-04-2011] Granular leukocyte Granular leukocyte[accessedResource: CL:0000094][accessDate: 05-04-2011] James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000522 mature neutrophil mast cell interneuron GABAergic interneuron James Malone Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.[accessedResource: CL:0000099][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000550 motor neuron An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.[accessedResource: CL:0000100][accessDate: 05-04-2011] NIFSTD:sao1460710779 Neurons which activate muscle cells (MSH). Neurons which activate muscle cells (MSH).[accessedResource: NIFSTD:sao1460710779][accessDate: 05-04-2011] Tomasz Adamusiak anterior horn cell anterior horn cell[accessedResource: CL:0000100][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002440 motoneuron motoneuron[accessedResource: CL:0000100][accessDate: 05-04-2011] sensory neuron Any neuron having a sensory function; an afferent neuron conveying sensory impulses. Any neuron having a sensory function; an afferent neuron conveying sensory impulses.[accessedResource: CL:0000101][accessDate: 05-04-2011] Ele Holloway James Malone http://www.ebi.ac.uk/efo/EFO_0002481 somatic nervous system A neuron that is part of nerve found outside the central nervous system. A neuron that is part of nerve found outside the central nervous system.[accessedResource: CL:0000111][accessDate: 05-04-2011] FMAID:9903 James Malone MA:0000230 MAT:0000099 PNS - somatic PNS - somatic[accessedResource: MAT:0000099][accessDate: 05-04-2011] Peripheral nervous system Peripheral nervous system[accessedResource: FMAID:9903][accessDate: 05-04-2011] SAEL:81 Tomasz Adamusiak WBbt:0005760 ZFA:0000070 http://www.ebi.ac.uk/efo/EFO_0000892 peripheral nerve peripheral nervous system - human peripheral neuron peripheral neuron[accessedResource: CL:0000111][accessDate: 05-04-2011] sensory axons peripheral sensory axons peripheral[accessedResource: ZFA:0000070][accessDate: 05-04-2011] columnar neuron James Malone http://www.ebi.ac.uk/efo/EFO_0000366 intermediolateral column motoneuron endothelial cell An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.[accessedResource: CL:0000115][accessDate: 05-04-2011] BTO:0001176 Endotheliocyte Endotheliocyte[accessedResource: CL:0000115][accessDate: 05-04-2011] James Malone The main type of cell found in the inside lining of blood vessels, lymph vessels, and the heart. The main type of cell found in the inside lining of blood vessels, lymph vessels, and the heart.[accessedResource: BTO:0001176][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000467 glial cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. (Reichenbach and Wolburg) A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. (Reichenbach and Wolburg)[accessedResource: NIFSTD:sao313023570][accessDate: 05-04-2011] A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.[accessedResource: CL:0000125][accessDate: 05-04-2011] BTO:0000524 James Malone MERGED DEFINITION:nTARGET DEFINITION: The delicate network of branched cells and fibers that supports the tissue of the central nervous system.n--------------------nSOURCE DEFINITION: The cells of the supportive tissue of the central nervous system (neuroglia). These non-neural cells are of three kinds: astrocytes, oligodendrocytes (collectively termed macroglia) and microglia. NIFSTD:sao313023570 The delicate network of branched cells and fibers that supports the tissue of the central nervous system. The delicate network of branched cells and fibers that supports the tissue of the central nervous system.[accessedResource: BTO:0000524][accessDate: 05-04-2011] Tomasz Adamusiak glia glia[accessedResource: NIFSTD:sao313023570][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000517 mixed glial cells neuroglia neuroglia cell neuroglial cell neuroglial cell[accessedResource: CL:0000125][accessDate: 05-04-2011] astrocyte A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with microglia) respond to injury (MSH). A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with microglia) respond to injury (MSH).[accessedResource: NIFSTD:sao1394521419][accessDate: 05-04-2011] A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury.[accessedResource: CL:0000127][accessDate: 05-04-2011] James Malone NIFSTD:sao1394521419 Tomasz Adamusiak cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and http://purl.obolibrary.org/obo/BTO_0000099 http://www.ebi.ac.uk/efo/EFO_0001996 oligodendrocyte A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.[accessedResource: CL:0000128][accessDate: 05-04-2011] A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as satellite cells, perineuronal of ganglia) according to their location. They form the insulating myelin sheath of axons in the central nervous system (MSH). A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as satellite cells, perineuronal of ganglia) according to their location. They form the insulating myelin sheath of axons in the central nervous system (MSH).[accessedResource: NIFSTD:sao844118448][accessDate: 05-04-2011] NIFSTD:sao844118448 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002442 oligodendroglia oligodendroglia[accessedResource: NIFSTD:sao844118448][accessDate: 05-04-2011] microglial cell A central nervous system macrophage found in the parenchyma of the central nervous system. A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive.[accessedResource: CL:0000129][accessDate: 05-04-2011] A small, migratory, phagocytic, interstitial cell of hematopoietic origin found in the central nervous system. Microglial cells are of various forms and may have slender branched processes. A small, migratory, phagocytic, interstitial cell of hematopoietic origin found in the central nervous system. Microglial cells are of various forms and may have slender branched processes.[accessedResource: NIFSTD:sao789292116][accessDate: 05-04-2011] BTO:0000078 Hortega cell James Malone MERGED DEFINITION:nTARGET DEFINITION: The small, non-neural, interstitial cells of mesodermal origin that form part of the supporting structure of the central nervous system. They are of various forms and may have slender branched processes. They are migratory and act as phagocytes to waste products of nerve tissue. n--------------------nSOURCE DEFINITION: One of the small interstitial phagocytic cells of the microglia. NIFSTD:sao789292116 The small, non-neural, interstitial cells of mesodermal origin that form part of the supporting structure of the central nervous system. They are of various forms and may have slender branched processes. They are migratory and act as phagocytes to waste products of nerve tissue. The small, non-neural, interstitial cells of mesodermal origin that form part of the supporting structure of the central nervous system. They are of various forms and may have slender branched processes. They are migratory and act as phagocytes to waste products of nerve tissue.[accessedResource: BTO:0000078][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000590 microglia microglia[accessedResource: BTO:0000078][accessDate: 05-04-2011] microgliocyte mixed glial cells (predominantly microglia) fat cell A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.[accessedResource: CL:0000136][accessDate: 05-04-2011] A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of tryglycerides. James Malone adipocyte adipocyte[accessedResource: CL:0000136][accessDate: 05-04-2011] adipose cell adipose cell[accessedResource: CL:0000136][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002001 lipocyte chondrocyte James Malone Polymorphic cell that form cartilage. Polymorphic cell that form cartilage.[accessedResource: CL:0000138][accessDate: 05-04-2011] cartilage cell cartilage cell[accessedResource: CL:0000138][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0001374 melanocyte A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance. A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance.[accessedResource: CL:0000148][accessDate: 05-04-2011] An epidermal cell that produces melanin. An epidermal cell that produces melanin.[accessedResource: BTO:0000847][accessDate: 05-04-2011] BTO:0000847 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002437 melanophore secretory cell A cell that specializes in controlled release of one or more substances. A cell that specializes in controlled release of one or more substances.[accessedResource: CL:0000151][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002446 parietal cell A large, oval stomach epithelial cell with a central nucleus; source of gastric acid. Secretes HCl. A large, oval stomach epithelial cell with a central nucleus; source of gastric acid. Secretes HCl.[accessedResource: CL:0000162][accessDate: 05-04-2011] James Malone http://www.ebi.ac.uk/efo/EFO_0000642 oxyntic cell oxyntic cell[accessedResource: CL:0000162][accessDate: 05-04-2011] neuroendocrine cell A neuron that has the specialized function to produce and secrete hormones, and that constitutes, in whole or in part, an endocrine organ or system. A neuron that has the specialized function to produce and secrete hormones, and that constitutes, in whole or in part, an endocrine organ or system.[accessedResource: CL:0000165][accessDate: 05-04-2011] BTO:0002691 Neuroendocrine cells are cells that receive neuronal input (neurotransmitters released by nerve cells) and, as a consequence of this input, release message molecules (hormones) to the blood. An example of a neuroendocrine cell is the cell of the adrenal medulla which releases adrenalin to the blood. The major center of neuroendocrine integration in the body is found in the hypothalamus and the pituitary gland. Here hypothalamic neurosecretory cells release factors to the blood. Neuroendocrine cells are cells that receive neuronal input (neurotransmitters released by nerve cells) and, as a consequence of this input, release message molecules (hormones) to the blood. An example of a neuroendocrine cell is the cell of the adrenal medulla which releases adrenalin to the blood. The major center of neuroendocrine integration in the body is found in the hypothalamus and the pituitary gland. Here hypothalamic neurosecretory cells release factors to the blood.[accessedResource: BTO:0002691][accessDate: 05-04-2011] Neuroendocrine cells are cells that receive neuronal input (neurotransmitters released by nerve cells) and, as a consequence of this input, release message molecules (hormones) to the blood. In this way they bring about and integration between the nervous system and the endocrine system, a process known as neuroendocrine integration. An example of a neuroendocrine cell is the cell of the adrenal medulla (innermost part of the adrenal gland) which releases adrenalin to the blood. The adrenal medullary cells are controlled by the sympathetic division of the autonomic nervous system. These cells are modified postganglionic neurons. Autonomic nerve fibers lead directly to them from the central nervous system. The major center of neuroendocrine integration in the body is found in the hypothalamus and the pituitary gland. Here hypothalamic neurosecretory cells release factors to the blood. Some of these these factors, release at the median eminence, control the secretion of pituitary hormones, while others (the hormones oxytocin and vasopressin) are released directly to the peripheral circulation. Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0003059 neurosecretory cell neurosecretory cell[accessedResource: CL:0000165][accessDate: 05-04-2011] beta cell A cell that composes the bulk of the islets of Langerhans and secretes insulin. A cell that composes the bulk of the islets of Langerhans and secretes insulin.[accessedResource: NCIt:C32199][accessDate: 05-04-2011] Insulin Cell Insulin Cell[accessedResource: NCIt:C32199][accessDate: 05-04-2011] Insulin Secreting Cell Insulin Secreting Cell[accessedResource: NCIt:C32199][accessDate: 05-04-2011] James Malone NCIt:C32199 Tomasz Adamusiak beta cell islets http://www.ebi.ac.uk/efo/EFO_0000285 alpha cell A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon. A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon.[accessedResource: CL:0000171][accessDate: 05-04-2011] Jie Zheng Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002539 pancreatic A cell pancreatic A cell[accessedResource: CL:0000171][accessDate: 05-04-2011] pancreatic alpha cell pancreatic alpha cell[accessedResource: CL:0000171][accessDate: 05-04-2011] Leydig cell A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.[accessedResource: CL:0000178][accessDate: 05-04-2011] James Malone http://www.ebi.ac.uk/efo/EFO_0000567 interstitial cell interstitial cell[accessedResource: CL:0000178][accessDate: 05-04-2011] testis - leydig cell hepatocyte A liver cell. A liver cell.[accessedResource: BTO:0000575][accessDate: 05-04-2011] BTO:0000575 James Malone The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated. The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.[accessedResource: CL:0000182][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000528 muscle cell A mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. A mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. This cell has as part of its cytoplasm myofibrils organized in various patterns. A mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. This cell has as part of its cytoplasm myofibrils organized in various patterns.[accessedResource: CL:0000187][accessDate: 05-04-2011] James Malone Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (muscle fibers), cardiac (myocytes, cardiac), and smooth (myocytes, smooth muscle). They are derived from embryonic (precursor) muscle cells called myoblasts (MSH). Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (muscle fibers), cardiac (myocytes, cardiac), and smooth (myocytes, smooth muscle). They are derived from embryonic (precursor) muscle cells called myoblasts (MSH).[accessedResource: NIFSTD:sao519252327][accessDate: 05-04-2011] NIFSTD:sao519252327 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000609 myocyte myocyte[accessedResource: CL:0000187][accessDate: 05-04-2011] skeletal muscle A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles. A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.[accessedResource: MSH:D018482][accessDate: 05-04-2011] A usually voluntary muscle made up of elongated, multinucleated, transversely striated muscle fibers, having principally bony attachments. A usually voluntary muscle made up of elongated, multinucleated, transversely striated muscle fibers, having principally bony attachments.[accessedResource: BTO:0001103][accessDate: 05-04-2011] Anterior Tibial Muscle Anterior Tibial Muscle[accessedResource: MSH:D018482][accessDate: 05-04-2011] BFBbt:00003259 BTO:0001103 EHDAA:5031 EMAPA:17745 EV:0100377 FMAID:5022 Gastrocnemius Muscle[accessedResource: MSH:D018482][accessDate: 05-04-2011] James Malone Jon Ison MAT:0000302 MSH:D018482 MUSCLE SKELETAL MUSCLE SKELETAL[accessedResource: MSH:D018482][accessDate: 05-04-2011] MUSCLE VOLUNTARY MUSCLE VOLUNTARY[accessedResource: MSH:D018482][accessDate: 05-04-2011] Muscle organ Muscle organ[accessedResource: FMAID:5022][accessDate: 05-04-2011] Muscle, Anterior Tibial Muscle, Anterior Tibial[accessedResource: MSH:D018482][accessDate: 05-04-2011] Muscle, Gastrocnemius[accessedResource: MSH:D018482][accessDate: 05-04-2011] Muscle, Plantaris Muscle, Plantaris[accessedResource: MSH:D018482][accessDate: 05-04-2011] Muscle, Skeletal Muscle, Skeletal[accessedResource: MSH:D018482][accessDate: 05-04-2011] Muscle, Soleus Muscle, Soleus[accessedResource: MSH:D018482][accessDate: 05-04-2011] Muscle, Voluntary Muscle, Voluntary[accessedResource: MSH:D018482][accessDate: 05-04-2011] Muscles, Skeletal Muscles, Skeletal[accessedResource: MSH:D018482][accessDate: 05-04-2011] Muscles, Voluntary Muscles, Voluntary[accessedResource: MSH:D018482][accessDate: 05-04-2011] Nonparenchymatous organ that primarily consists of skeletal muscle tissue aggregated into macroscopic fasciculi by connective tissue; together with other muscles, it constitutes the muscular system. Examples: biceps, diaphragm, masseter, right third external intercostal muscle, external oblique, levator ani, serratus anterior. Plantaris Muscle Plantaris Muscle[accessedResource: MSH:D018482][accessDate: 05-04-2011] SAEL:94 Skeletal Muscles Skeletal Muscles[accessedResource: MSH:D018482][accessDate: 05-04-2011] Skeletal muscle fiber Skeletal muscle fiber[accessedResource: CL:0000188][accessDate: 05-04-2011] Soleus Muscle Soleus Muscle[accessedResource: MSH:D018482][accessDate: 05-04-2011] Striated muscle cell which has as its direct parts two or more peripherally located nuclei. Striated muscle cell which has as its direct parts two or more peripherally located nuclei.[accessedResource: CL:0000188][accessDate: 05-04-2011] Tibial Muscle, Anterior Tibial Muscle, Anterior[accessedResource: MSH:D018482][accessDate: 05-04-2011] Tomasz Adamusiak Voluntary Muscle Voluntary Muscle[accessedResource: MSH:D018482][accessDate: 05-04-2011] Voluntary Muscles Voluntary Muscles[accessedResource: MSH:D018482][accessDate: 05-04-2011] XAO:0000174 adult somatic muscle http://www.ebi.ac.uk/efo/EFO_0000888 muscle organ - human skeletal muscle cell skeletal muscle cell[accessedResource: CL:0000188][accessDate: 05-04-2011] skeletal muscle system skeletal muscle system[accessedResource: MAT:0000302][accessDate: 05-04-2011] somatic muscle striated muscle striated muscle cell smooth muscle cell A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).[accessedResource: CL:0000192][accessDate: 05-04-2011] James Malone NIFSTD:sao676858164 Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (myoblasts, smooth muscle) (MSH). Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (myoblasts, smooth muscle) (MSH).[accessedResource: NIFSTD:sao676858164][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000703 non-striated muscle cell non-striated muscle cell[accessedResource: CL:0000192][accessDate: 05-04-2011] smooth muscle fiber smooth muscle fiber[accessedResource: CL:0000192][accessDate: 05-04-2011] cochlear hair cell A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system.[accessedResource: CL:0000202][accessDate: 05-04-2011] A mechanoreceptor cell located in the organ of Corti that is sensitive to auditory stimuli and in the vestibular apparatus that is sensitive to movement of the head. In each case the accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. James Malone NIFSTD:sao630986029 Tomasz Adamusiak auditory hair cell auditory hair cell[accessedResource: CL:0000202][accessDate: 05-04-2011] auditory receptor cell auditory receptor cell[accessedResource: CL:0000202][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000358 Sertoli cell A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier. A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier.[accessedResource: CL:0000216][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002447 Schwann cell A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons. A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons.[accessedResource: CL:0000218][accessDate: 05-04-2011] James Malone Neurilemmal cell Neurilemmal cell[accessedResource: CL:0000218][accessDate: 05-04-2011] Peripheral neuroglial cell http://www.ebi.ac.uk/efo/EFO_0002000 myelinating Schwann cell myelinating Schwann cell[accessedResource: CL:0000218][accessDate: 05-04-2011] mesodermal cell A cell of the middle germ layer of the embryo. A cell of the middle germ layer of the embryo.[accessedResource: CL:0000222][accessDate: 05-04-2011] James Malone http://www.ebi.ac.uk/efo/EFO_0000587 mesoblast mesoblast[accessedResource: CL:0000222][accessDate: 05-04-2011] mesoderm cell mesoderm cell[accessedResource: CL:0000222][accessDate: 05-04-2011] erythrocyte A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.[accessedResource: CL:0000232][accessDate: 05-04-2011] A red blood cell. In mammals, mature erythrocytes are non-nucleated, biconcave disks containing hemoglobin whose function is to transport oxygen. Any of the hemoglobin-containing cells that carry oxygen to the tissues and are responsible for the red color of vertebrate blood. Any of the hemoglobin-containing cells that carry oxygen to the tissues and are responsible for the red color of vertebrate blood.[accessedResource: BTO:0000424][accessDate: 05-04-2011] BTO:0000424 James Malone RBC RBC[accessedResource: CL:0000232][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000477 red blood cell red blood cell[accessedResource: CL:0000232][accessDate: 05-04-2011] red blood corpuscle platelet A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.[accessedResource: CL:0000233][accessDate: 05-04-2011] James Malone MSH:D001792 Tomasz Adamusiak blood platelet blood platelet[accessedResource: CL:0000233][accessDate: 05-04-2011] blood platelets http://www.ebi.ac.uk/efo/EFO_0000656 thrombocyte true macrophage A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.[accessedResource: CL:0000235][accessDate: 05-04-2011] A mononuclear phagocyte which differentiates from monocytes, is typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells (Cell Ontology). A mononuclear phagocyte which differentiates from monocytes, is typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells (Cell Ontology).[accessedResource: NIFSTD:sao185843373][accessDate: 05-04-2011] BTO:0000801 James Malone NIFSTD:sao185843373 Relatively long-lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), Kuppfer cells of the liver, and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa, and tumour cells, release substances that stimulate other cells of the immune system, and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or Langhans' giant cells. Relatively long-lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), Kuppfer cells of the liver, and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa, and tumour cells, release substances that stimulate other cells of the immune system, and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or Langhans' giant cells.[accessedResource: BTO:0000801][accessDate: 05-04-2011] Tomasz Adamusiak bone marrow-derived macrophage histiocyte histiocyte[accessedResource: CL:0000235][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000575 macrophagocyte monocyte-derived macrophage B cell A lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. A lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.[accessedResource: CL:0000236][accessDate: 05-04-2011] A lymphocyte of B lineage with the phenotype CD19-positive and surface immunoglobulin-positive. B Cells B Cells[accessedResource: NCIt:C12474][accessDate: 05-04-2011] B Lymphocytes B Lymphocytes[accessedResource: NCIt:C12474][accessDate: 05-04-2011] B lymphocyte B lymphocyte[accessedResource: CL:0000236][accessDate: 05-04-2011] B-Cells B-Cells[accessedResource: NCIt:C12474][accessDate: 05-04-2011] B-Lymphocyte[accessedResource: NCIt:C12474][accessDate: 05-04-2011] B-Lymphocytes B-Lymphocytes[accessedResource: NCIt:C12474][accessDate: 05-04-2011] B-cell B-cell[accessedResource: CL:0000236][accessDate: 05-04-2011] B-lymphocyte Bursa-Dependent Lymphocytes Bursa-Dependent Lymphocytes[accessedResource: NCIt:C12474][accessDate: 05-04-2011] Bursa-Equivalent Lymphocyte Bursa-Equivalent Lymphocyte[accessedResource: NCIt:C12474][accessDate: 05-04-2011] Immunologically important lymphocyte that is not thymus-dependent, is either short-lived and naive or long-lived and of memory phenotype, and resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins. Immunologically important lymphocyte that is not thymus-dependent, is either short-lived and naive or long-lived and of memory phenotype, and resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins.[accessedResource: NCIt:C12474][accessDate: 05-04-2011] James Malone NCIt:C12474 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000101 megaspore A haploid (1n) spore developing into a female gametophyte in heterosporous plants. A haploid (1n) spore developing into a female gametophyte in heterosporous plants.[accessedResource: CL:0000250][accessDate: 05-04-2011] James Malone MAT:0000214 OntologyMappingImporter following MAT:0000214 PO:0020019 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001001 microspore A haploid (1n) spore developing into a male gametophyte in heterosporous plants; the uninucleate pollen grain in seed plants. A haploid (1n) spore developing into a male gametophyte in heterosporous plants; the uninucleate pollen grain in seed plants.[accessedResource: CL:0000252][accessDate: 05-04-2011] BTO:0000124 BTO:0001097 GRO:0005650 Haploid cells produced by meiosis in the anthers of angiosperms; four microspores are produced from a single microsporocyte. Haploid cells produced by meiosis in the anthers of angiosperms; four microspores are produced from a single microsporocyte.[accessedResource: BTO:0000124][accessDate: 05-04-2011] James Malone MAT:0000215 MAT:0000216 PO:0020048 PO:0020097 The structure into which a haploid microspore develops; contains a halpoid tube nucleus and two haploid sperm nuclei at maturity. The structure into which a haploid microspore develops; contains a halpoid tube nucleus and two haploid sperm nuclei at maturity.[accessedResource: BTO:0001097][accessDate: 05-04-2011] Tomasz Adamusiak generative cell (male) http://www.ebi.ac.uk/efo/EFO_0001002 http://www.ebi.ac.uk/efo/EFO_0001003 microspore[accessedResource: CL:0000252][accessDate: 05-04-2011] pollen pollen grain guard cell One of a pair of cells flanking the stomatal pore and causing the opening and closing of the pore by changes in turgor. One of a pair of cells flanking the stomatal pore and causing the opening and closing of the pore by changes in turgor.[accessedResource: CL:0000292][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002435 stomatal guard cell stomatal guard cell[accessedResource: CL:0000292][accessDate: 05-04-2011] keratinocyte An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.[accessedResource: CL:0000312][accessDate: 05-04-2011] BTO:0000667 James Malone Skin cell, of the keratinized layer of epidermis: its characteristic intermediate filament protein is cytokeratin. Skin cell, of the keratinized layer of epidermis: its characteristic intermediate filament protein is cytokeratin.nA cell of the stratum spinosum of the epidermis. Skin cell, of the keratinized layer of epidermis: its characteristic intermediate filament protein is cytokeratin.nA cell of the stratum spinosum of the epidermis.[accessedResource: BTO:0000667][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000560 malpighian cell malpighian cell[accessedResource: CL:0000312][accessDate: 05-04-2011] neural crest cell A cell of the strip of specialized ectoderm flanking each side of the embryonal neural plate, which after the closure of the neural tube, forms a column of isolated cells along the dorsal aspect of the neural tube. Most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells. A cell of the strip of specialized ectoderm flanking each side of the embryonal neural plate, which after the closure of the neural tube, forms a column of isolated cells along the dorsal aspect of the neural tube. Most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells.[accessedResource: CL:0000333][accessDate: 05-04-2011] James Malone http://www.ebi.ac.uk/efo/EFO_0000619 adrenal gland A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation. A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation.[accessedResource: CL:0000336][accessDate: 05-04-2011] A flattened, roughly triangular body resting upon the upper end of each kidney; it is one of the ductless glands furnishing internal secretions (epinephrine and norepinephrine from the medulla and steroid hormones from the cortex). A flattened, roughly triangular body resting upon the upper end of each kidney; it is one of the ductless glands furnishing internal secretions (epinephrine and norepinephrine from the medulla and steroid hormones from the cortex).[accessedResource: NCIt:C12666][accessDate: 05-04-2011] Adrenal Glands Adrenal Glands[accessedResource: NCIt:C12666][accessDate: 05-04-2011] Adrenals Adrenals[accessedResource: NCIt:C12666][accessDate: 05-04-2011] BTO:0000047 EMAPA:18426 EV:0100135 Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine. Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine.[accessedResource: BTO:0000047][accessDate: 05-04-2011] FMAID:9604 James Malone MA:0000116 MAT:0000071 NCIt:C12666 SAEL:3 Suprarenal gland Suprarenal gland[accessedResource: FMAID:9604][accessDate: 05-04-2011] TAO:0009167 Tomasz Adamusiak XAO:0000164 adrenal adrenal capsule adrenal medulla cell adrenal medulla cell[accessedResource: TAO:0009167][accessDate: 05-04-2011] adrenal medulla chromaffin cell adrenal medulla chromaffin cell[accessedResource: CL:0000336][accessDate: 05-04-2011] atrabiliary capsule chromafin cell chromafin cell[accessedResource: CL:0000336][accessDate: 05-04-2011] epinephros glandula suprarenalis http://www.ebi.ac.uk/efo/EFO_0000238 suprarenal capsule neuroblast (sensu Vertebrata) An embryonic cell that develops into a nerve cell or neuron. An embryonic cell that develops into a nerve cell or neuron.[accessedResource: CL:0000337][accessDate: 05-04-2011] James Malone Tomasz Adamusiak adrenal neuroblast http://www.ebi.ac.uk/efo/EFO_0000620 neuroblast neuroblast[accessedResource: CL:0000031][accessDate: 05-04-2011] epiblast cell A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation. A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation.[accessedResource: CL:0000352][accessDate: 05-04-2011] James Malone embryonic stem cell epiblast stem cell http://www.ebi.ac.uk/efo/EFO_0000471 zygote Diploid cell produced by the fusion of sperm cell nucleus and egg cell. Diploid cell produced by the fusion of sperm cell nucleus and egg cell.[accessedResource: CL:0000365][accessDate: 05-04-2011] The stage at which a diploid cell is produced by the fusion of sperm cell nucleus and egg cell. Tomasz Adamusiak ZFS:0000001 Zygote:1-cell Zygote:1-cell[accessedResource: ZFS:0000001][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002952 protoplast The cell protoplasm after removal of the cell wall. The cell protoplasm after removal of the cell wall.[accessedResource: CL:0000371][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002445 ligament cell Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0003080 prohemocyte (sensu Nematoda and Protostomia) hemocyte A blood cell especially of an invertebrate animal. A blood cell especially of an invertebrate animal.[accessedResource: BTO:0000571][accessDate: 05-04-2011] BTO:0000571 Tomasz Adamusiak haematocyte haemocyte hematocyte hemocyte (sensu Nematoda and Protostomia) hemocyte (sensu Nematoda and Protostomia)[accessedResource: CL:0000387][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002450 connective tissue BTO:0000421 Bindegewebe EV:0100150 FMAID:9640 James Malone MAT:0000301 Portion of connective tissue Portion of connective tissue[accessedResource: FMAID:9640][accessDate: 05-04-2011] SAEL:23 TAO:0009189 The tissue which binds together and is the support of the various structures of the body. It is made up of fibroblasts, fibroglia, collagen fibrils, and elastic fibrils. It is derived from the mesoderm and in a broad sense includes the collagenous, elastic, mucous, reticular, osseous, and cartilaginous tissue. Some also include the blood in this group of tissues. Connective tissue is classified according to concentration of fibers as loose (areolar) and dense, the latter having more abundant fibers than the former. The tissue which binds together and is the support of the various structures of the body. It is made up of fibroblasts, fibroglia, collagen fibrils, and elastic fibrils. It is derived from the mesoderm and in a broad sense includes the collagenous, elastic, mucous, reticular, osseous, and cartilaginous tissue. Some also include the blood in this group of tissues. Connective tissue is classified according to concentration of fibers as loose (areolar) and dense, the latter having more abundant fibers than the former.[accessedResource: BTO:0000421][accessDate: 05-04-2011] Tissue which consists of fibroblasts, osteocytes or chondrocytes and intercellular matrix produced by these cells. Examples: bone (tissue), dense regular elastic tissue, areolar tissue, neuroglia, adipose tissue. Tomasz Adamusiak XAO:0000173 fascia http://www.ebi.ac.uk/efo/EFO_0000952 muscle attachment cell muscle attachment cell[accessedResource: CL:0000388][accessDate: 05-04-2011] tendon tendon cell tendon cell[accessedResource: CL:0000388][accessDate: 05-04-2011] blood cell (sensu Nematoda and Protostomia) crystal cell A cell that is slightly larger than the plasmatocytes and is distinguished by containing large crystalline inclusions that are not membrane bound (Brehelin, 1982). A cell that is slightly larger than the plasmatocytes and is distinguished by containing large crystalline inclusions that are not membrane bound (Brehelin, 1982).[accessedResource: FBbt:00001690][accessDate: 05-04-2011] FBbt:00001690 James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000385 parathyroid An epithelial cell of the parathyroid gland that is arranged in wide, irregular interconnecting columns; responsible for the synthesis and secretion of parathyroid hormone. An epithelial cell of the parathyroid gland that is arranged in wide, irregular interconnecting columns; responsible for the synthesis and secretion of parathyroid hormone.[accessedResource: CL:0000446][accessDate: 05-04-2011] Any of usually four small endocrine glands that are adjacent to or embedded in the thyroid gland and produce parathyroid hormone. Any of usually four small endocrine glands that are adjacent to or embedded in the thyroid gland and produce parathyroid hormone.[accessedResource: BTO:0000997][accessDate: 05-04-2011] BTO:0000997 EHDAA:3864 EHDAA:3870 EV:0100134 FMAID:13890 James Malone MA:0000128 Parathyroid chief cell Parathyroid chief cell[accessedResource: CL:0000446][accessDate: 05-04-2011] Parathyroid gland Parathyroid gland chief cell Parathyroid gland chief cell[accessedResource: CL:0000446][accessDate: 05-04-2011] Principal cell of parathyroid gland Principal cell of parathyroid gland[accessedResource: CL:0000446][accessDate: 05-04-2011] TAO:0009207 Tomasz Adamusiak XAO:0000167 chief cell chief cell of parathyroid gland chief cell of parathyroid gland[accessedResource: CL:0000446][accessDate: 05-04-2011] chief cell[accessedResource: TAO:0009207][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000862 parathyroid gland[accessedResource: BTO:0000997][accessDate: 05-04-2011] parathyroid hormone secreting cell parathyroid hormone secreting cell[accessedResource: CL:0000446][accessDate: 05-04-2011] brown fat cell A cell from the thermogenic form of adipose tissue found in newborns of many species, including humans, and in hibernating mammals. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation. A cell from the thermogenic form of adipose tissue found in newborns of many species, including humans, and in hibernating mammals. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation.[accessedResource: CL:0000449][accessDate: 05-04-2011] Brown adipocyte Brown adipocyte[accessedResource: CL:0000449][accessDate: 05-04-2011] Brown adipose cell Brown adipose cell[accessedResource: CL:0000449][accessDate: 05-04-2011] James Malone http://www.ebi.ac.uk/efo/EFO_0001998 dendritic cell A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.[accessedResource: CL:0000451][accessDate: 05-04-2011] A special type of cell that is a key regulator of the immune system, acting as a professional antigen-presenting cell, APC, capable of activating naive T cells and stimulating the growth and differentiation of B cells. Dendritic cells are found, for example, in the lymph nodes and spleen. As an APC, a dendritic cell can retain antigen for long periods on its surface, present the antigen to a T or B cell and so influence their behavior. A special type of cell that is a key regulator of the immune system, acting as a professional antigen-presenting cell, APC, capable of activating naive T cells and stimulating the growth and differentiation of B cells. Dendritic cells are found, for example, in the lymph nodes and spleen. As an APC, a dendritic cell can retain antigen for long periods on its surface, present the antigen to a T or B cell and so influence their behavior.[accessedResource: BTO:0002042][accessDate: 05-04-2011] BTO:0002042 CL:0000451 James Malone Large, stellate fibroblast found along the network of collagen fibers of the reticulum of the spleen; synthesize the matrix components of the reticulum. Large, stellate fibroblast found along the network of collagen fibers of the reticulum of the spleen; synthesize the matrix components of the reticulum.[accessedResource: CL:0000432][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000396 interdigitating cell reticular cell reticular cell[accessedResource: CL:0000432][accessDate: 05-04-2011] reticulum cell reticulum cell[accessedResource: CL:0000432][accessDate: 05-04-2011] veiled cell Langerhans cell follicle cell James Malone http://www.ebi.ac.uk/efo/EFO_0000498 connective tissue type mast cell mucosal type mast cell CD4-positive helper T cell stromal cell A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.[accessedResource: CL:0000499][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002448 granulosa cell A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors.[accessedResource: CL:0000501][accessDate: 05-04-2011] TO:0000542 granulosa cell of ovary granulosa cell of ovary[accessedResource: CL:0000501][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002664 smooth muscle myoblast A precursor cell destined to differentiate into smooth muscle myocytes. A precursor cell destined to differentiate into smooth muscle myocytes.[accessedResource: CL:0000514][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002452 satellite cell syncytiotrophoblast cell A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.[accessedResource: CL:0000525][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0003074 plasmidotrophoblast plasmidotrophoblast[accessedResource: CL:0000525][accessDate: 05-04-2011] syncytial trophoblast syncytial trophoblast[accessedResource: CL:0000525][accessDate: 05-04-2011] syntrophoblast syntrophoblast[accessedResource: CL:0000525][accessDate: 05-04-2011] neuron A grayish or reddish granular cell with specialized processes that is the fundamental functional unit of nervous tissue. A grayish or reddish granular cell with specialized processes that is the fundamental functional unit of nervous tissue.[accessedResource: BTO:0000938][accessDate: 05-04-2011] BTO:0000938 James Malone NIFSTD:sao1417703748 The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.[accessedResource: CL:0000540][accessDate: 05-04-2011] The basic cellular units of nervous tissue. Neurons are polarized cells with defined regions consisting of the cell body, an axon, and dendrites, although some types of neurons lack axons or dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000623 nerve cell nerve cell[accessedResource: CL:0000540][accessDate: 05-04-2011] neuron cell neuron cell[accessedResource: NIFSTD:sao1417703748][accessDate: 05-04-2011] neuronal cell lymphocyte A cell of the B cell, T cell, or natural killer cell lineage. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.[accessedResource: CL:0000542][accessDate: 05-04-2011] Any of the colorless weakly motile cells originating from stem cells and differentiating in lymphoid tissue (as of the thymus or bone marrow) that are the typical cellular elements of lymph, include the cellular mediators of immunity, and constitute 20 to 30 percent of the white blood cells of normal human blood. Any of the colorless weakly motile cells originating from stem cells and differentiating in lymphoid tissue (as of the thymus or bone marrow) that are the typical cellular elements of lymph, include the cellular mediators of immunity, and constitute 20 to 30 percent of the white blood cells of normal human blood.[accessedResource: BTO:0000775][accessDate: 05-04-2011] BTO:0000775 James Malone MSH:D008214 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000573 lymphocytes true T-helper 1 cell T-helper 2 cell proerythroblast An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.[accessedResource: CL:0000547][accessDate: 05-04-2011] Jie Zheng Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002537 pronormoblast rubriblast rubriblast[accessedResource: CL:0000547][accessDate: 05-04-2011] basophilic erythroblast A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers.[accessedResource: CL:0000549][accessDate: 05-04-2011] Jie Zheng Tomasz Adamusiak basophilic normoblast basophilic normoblast[accessedResource: CL:0000549][accessDate: 05-04-2011] early erythroblast early erythroblast[accessedResource: CL:0000549][accessDate: 05-04-2011] early normoblast early normoblast[accessedResource: CL:0000549][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002738 prorubricyte prorubricyte[accessedResource: CL:0000549][accessDate: 05-04-2011] polychromatophilic erythroblast orthochromatic erythroblast megakaryocyte progenitor cell James Malone The earliest cytologically identifiable precursor in the thrombocytic series. The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).[accessedResource: CL:0000553][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000583 megacaryoblast megacaryoblast[accessedResource: CL:0000553][accessDate: 05-04-2011] megacaryocyte progenitor cell megacaryocyte progenitor cell[accessedResource: CL:0000553][accessDate: 05-04-2011] megakaryoblast megakaryoblast[accessedResource: CL:0000553][accessDate: 05-04-2011] promegacaryocyte promegakaryocyte megakaryocyte A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm. A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm.[accessedResource: CL:0000556][accessDate: 05-04-2011] A large cell that has a lobulated nucleus, is found especially in the bone marrow, and is the source of blood platelets. A large cell that has a lobulated nucleus, is found especially in the bone marrow, and is the source of blood platelets.[accessedResource: BTO:0000843][accessDate: 05-04-2011] BTO:0000843 James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000582 megacaryocyte megacaryocyte[accessedResource: CL:0000556][accessDate: 05-04-2011] megalocaryocyte megalocaryocyte[accessedResource: CL:0000556][accessDate: 05-04-2011] megalokaryocyte megalokaryocyte[accessedResource: CL:0000556][accessDate: 05-04-2011] granulocyte monocyte progenitor cell A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata-1, Gata2 but do express C/EBPa, and Pu.1. A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata-1, Gata2 but do express C/EBPa, and Pu.1.[accessedResource: CL:0000557][accessDate: 05-04-2011] A progenitor cell that has plasma membrane part CD123, CD34, and CD45RA, lacks plasma membrane part CD19 and CD3, and is committed to the granulocyte and monocyte lineages. CFU-C , Colony forming unit in culture CFU-GM CFU-GM[accessedResource: CL:0000557][accessDate: 05-04-2011] GMP GMP[accessedResource: CL:0000557][accessDate: 05-04-2011] Tomasz Adamusiak colony forming unit granulocyte macrophage colony forming unit granulocyte macrophage[accessedResource: CL:0000557][accessDate: 05-04-2011] granulocyte monocyte progenitor cell granulocyte monocyte progenitor cell[accessedResource: CL:0000557][accessDate: 05-04-2011] granulocyte-macrophage progenitor http://www.ebi.ac.uk/efo/EFO_0002663 reticulocyte An immature erythrocyte showing a basophilic reticulum under vital staining. An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.[accessedResource: CL:0000558][accessDate: 05-04-2011] Jie Zheng Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002538 promonocyte band form neutrophil nucleate erythrocyte neutrophilic promyelocyte monocyte A mononuclear phagocytic leukocyte, 13 to 25 mm in diameter, with an ovoid or kidney-shaped nucleus, containing lacy, linear chromatin and abundant gray-blue cytoplasm filled with fine reddish and azurophilic granules. Formed in the bone marrow from promonocytes, monocytes are transported to tissues such as the lung and liver, where they develop into macrophages. A mononuclear phagocytic leukocyte, 13 to 25 mm in diameter, with an ovoid or kidney-shaped nucleus, containing lacy, linear chromatin and abundant gray-blue cytoplasm filled with fine reddish and azurophilic granules. Formed in the bone marrow from promonocytes, monocytes are transported to tissues such as the lung and liver, where they develop into macrophages.[accessedResource: BTO:0000876][accessDate: 05-04-2011] BTO:0000876 James Malone MSH:D009000 Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.[accessedResource: CL:0000576][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000593 monocytes mononuclear leukocyte nongranular leukocyte true border follicle cell A follicle cell that migrates from the anterior pole of the egg chamber, between the nurse cells, to the anterior of the oocyte where they participate in formation of the micropyle. About 6-10 border cells per egg chamber migrate as a tightly associated cluster. A follicle cell that migrates from the anterior pole of the egg chamber, between the nurse cells, to the anterior of the oocyte where they participate in formation of the micropyle. About 6-10 border cells per egg chamber migrate as a tightly associated cluster. A follicle cell that migrates from the anterior pole of the egg chamber, between the nurse cells, to the anterior of the oocyte where they participate in formation of the micropyle. About 6-10 border cells per egg chamber migrate as a tightly associated cluster.[accessedResource: FBbt:00004905][accessDate: 05-04-2011] FBbt:00004905 Tomasz Adamusiak border cell http://www.ebi.ac.uk/efo/EFO_0002432 neutrophilic myelocyte peritoneal macrophage neutrophilic metamyelocyte alveolar macrophage germ cell Jie Zheng The reproductive cell in multicellular organisms. The reproductive cell in multicellular organisms.[accessedResource: CL:0000586][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002531 odontoclast enucleate erythrocyte plant cell A cell found in seeded plants. A cell found in seeded plants.[accessedResource: CL:0000610][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002965 eosinophil progenitor cell eosinophilic myelocyte basophil progenitor cell basophilic myelocyte GABAergic neuron A neuron that uses GABA as a vesicular neurotransmitter A neuron that uses GABA as a vesicular neurotransmitter[accessedResource: CL:0000617][accessDate: 05-04-2011] GABA-ergic neuron GABA-ergic neuron[accessedResource: CL:0000617][accessDate: 05-04-2011] James Malone http://www.ebi.ac.uk/efo/EFO_0000177 acinar cell A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus).[accessedResource: CL:0000622][accessDate: 05-04-2011] Jie Zheng Tomasz Adamusiak acinic cell acinic cell[accessedResource: CL:0000622][accessDate: 05-04-2011] acinous cell acinous cell[accessedResource: CL:0000622][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002530 pancreatic acinar cell natural killer cell A large granular lymphocyte capable of killing a tumor or microbial cell without prior exposure to the target cell and without having it presented with or marked by a histocompatibility antigen. A large granular lymphocyte capable of killing a tumor or microbial cell without prior exposure to the target cell and without having it presented with or marked by a histocompatibility antigen.[accessedResource: BTO:0000914][accessDate: 05-04-2011] A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells. A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.[accessedResource: CL:0000623][accessDate: 05-04-2011] BTO:0000914 James Malone NK cell NK cell[accessedResource: CL:0000623][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000615 large granular lymphocyte natural killer null cell CD4-positive, alpha-beta T cell CD8-positive, alpha-beta T cell basal cell James Malone Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament. Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament.[accessedResource: CL:0000646][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0001997 multinucleated giant cell pericyte *Slender, contractile, mesenchymal-like cell found in close association with capillary walls. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. (From OBO Cell Type Ontology). *A flattened, or elongated, stellate-shaped solitary cell with multiple cytoplasmic processes encircling the capillary endothelium and contacting a large abluminal vessel area. It may be equivalent to the vascular smooth muscle cell, although this identify has not been conclusively determined yet (Armulik et al., Circ Res 97: 512, 2005). *Slender, contractile, mesenchymal-like cell found in close association with capillary walls. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. (From OBO Cell Type Ontology). *A flattened, or elongated, stellate-shaped solitary cell with multiple cytoplasmic processes encircling the capillary endothelium and contacting a large abluminal vessel area. It may be equivalent to the vascular smooth muscle cell, although this identify has not been conclusively determined yet (Armulik et al., Circ Res 97: 512, 2005).[accessedResource: NIFSTD:nifext_171][accessDate: 05-04-2011] A slender, contractile, mesenchymal-like cell found in close association with capillary walls. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. (From Stedman, 26th ed). An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells.[accessedResource: CL:0000184][accessDate: 05-04-2011] Cell of Rouget Cell of Rouget[accessedResource: CL:0000184][accessDate: 05-04-2011] Mural Cell Mural Cell[accessedResource: NIFSTD:nifext_171][accessDate: 05-04-2011] NIFSTD:nifext_171 Pericyte of Rouget Pericyte of Rouget[accessedResource: CL:0000669][accessDate: 05-04-2011] Rouget Cell Rouget Cell[accessedResource: NIFSTD:nifext_171][accessDate: 05-04-2011] Tomasz Adamusiak adventitial cell adventitial cell[accessedResource: CL:0000669][accessDate: 05-04-2011] adventitial reticular cell adventitial reticular cell[accessedResource: CL:0000669][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002444 pericyte cell pericyte cell[accessedResource: CL:0000184][accessDate: 05-04-2011] primordial germ cell A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells.[accessedResource: CL:0000670][accessDate: 05-04-2011] Gonocyte Gonocyte[accessedResource: CL:0000670][accessDate: 05-04-2011] James Malone Primitive germ cell Primitive germ cell[accessedResource: CL:0000670][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000670 glutamatergic neuron James Malone http://www.ebi.ac.uk/efo/EFO_0000521 leukocyte A nucleated cell of the myeloid or lymphoid lineages, found in blood or other tissue. An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.[accessedResource: CL:0000738][accessDate: 05-04-2011] Any of the blood cells that are colorless, lack hemoglobin, contain a nucleus, and include the lymphocytes, monocytes, neutrophils, eosinophils, and basophils. Any of the blood cells that are colorless, lack hemoglobin, contain a nucleus, and include the lymphocytes, monocytes, neutrophils, eosinophils, and basophils.[accessedResource: BTO:0000751][accessDate: 05-04-2011] BTO:0000751 James Malone PMN cell PMNC Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000566 immune cell immune cell[accessedResource: CL:0000738][accessDate: 05-04-2011] leucocyte leucocyte[accessedResource: CL:0000738][accessDate: 05-04-2011] polymorphonuclear cell white blood cell white blood cell type white blood cell types white blood cell[accessedResource: CL:0000738][accessDate: 05-04-2011] cardiac myocyte A heart muscle cell. A heart muscle cell.[accessedResource: BTO:0001539][accessDate: 05-04-2011] A myocyte located in the heart. The contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. A myocyte located in the heart. The contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.[accessedResource: CL:0000746][accessDate: 05-04-2011] A striated muscle cell found in the heart. They develop from cardiac myoblasts. A striated muscle cell found in the heart. They develop from cardiac myoblasts.[accessedResource: CL:0000193][accessDate: 05-04-2011] BTO:0001539 James Malone NIFSTD:sao658938043 Striated muscle cells found in the heart. They are derived from cardiac myoblasts (myoblasts, cardiac (MSH). Striated muscle cells found in the heart. They are derived from cardiac myoblasts (myoblasts, cardiac (MSH).[accessedResource: NIFSTD:sao658938043][accessDate: 05-04-2011] Tomasz Adamusiak cardiac muscle cell cardiac muscle cell (sensu Arthopoda) cardiac muscle cell (sensu Arthopoda)[accessedResource: CL:0000193][accessDate: 05-04-2011] cardiac muscle cell[accessedResource: CL:0000746][accessDate: 05-04-2011] cardiocyte cardiocyte[accessedResource: CL:0000193][accessDate: 05-04-2011] cardiomyocyte cardiomyocyte[accessedResource: CL:0000746][accessDate: 05-04-2011] heart muscle cell heart muscle cell[accessedResource: CL:0000193][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000316 nucleated thrombocyte myeloid cell A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.[accessedResource: CL:0000763][accessDate: 05-04-2011] Any of the immature blood cells that develop in the bone marrow, such as those involved in hematopoiesis. Any of the immature blood cells that develop in the bone marrow, such as those involved in hematopoiesis.[accessedResource: BTO:0001441][accessDate: 05-04-2011] BTO:0001441 James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000610 marrow cell marrow cell[accessedResource: BTO:0001441][accessDate: 05-04-2011] erythroid lineage cell erythroblast A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.[accessedResource: CL:0000765][accessDate: 05-04-2011] A nucleated precursor of an erythrocyte. James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001999 normoblast normoblast[accessedResource: CL:0000765][accessDate: 05-04-2011] myeloid leukocyte basophil Dani Welter Granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic dyes. MSH:D001491 basophils true immature basophil basophilic metamyelocyte band form basophil eosinophil Dani Welter Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin. MSH:D004804 eosinophils true immature eosinophil eosinophilic metamyelocyte band form eosinophil neutrophil A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation.[accessedResource: CL:0000043][accessDate: 05-04-2011] A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.[accessedResource: CL:0000775][accessDate: 05-04-2011] Ele Holloway James Malone MSH:D009504 PMN Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002480 mature basophil mature basophil leucocyte mature basophil leucocyte[accessedResource: CL:0000043][accessDate: 05-04-2011] mature basophil leukocyte mature basophil leukocyte[accessedResource: CL:0000043][accessDate: 05-04-2011] mature basophil[accessedResource: CL:0000043][accessDate: 05-04-2011] neutrocyte neutrocyte[accessedResource: CL:0000775][accessDate: 05-04-2011] neutrophil leucocyte neutrophil leucocyte[accessedResource: CL:0000775][accessDate: 05-04-2011] neutrophil leukocyte neutrophil leukocyte[accessedResource: CL:0000775][accessDate: 05-04-2011] neutrophilic leucocyte neutrophilic leucocyte[accessedResource: CL:0000775][accessDate: 05-04-2011] neutrophilic leukocyte neutrophilic leukocyte[accessedResource: CL:0000775][accessDate: 05-04-2011] neutrophils poly polymorphonuclear leucocyte polymorphonuclear leukocyte polymorphonuclear neutrophil polynuclear neutrophilic leucocyte polynuclear neutrophilic leukocyte true immature neutrophil mesangial phagocyte A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling. A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling.[accessedResource: CL:0000777][accessDate: 05-04-2011] A tissue-resident macrophage of the renal glomerular mesangium. James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000585 mesangial cell mononuclear osteoclast multinuclear osteoclast multinuclear odontoclast mononuclear odontoclast myeloid dendritic cell plasmacytoid dendritic cell A dendritic cell type of distinct morphology, localization, and surface marker expression from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection. A dendritic cell type of distinct morphology, localization, and surface marker expression from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection.[accessedResource: CL:0000784][accessDate: 05-04-2011] DC2 DC2[accessedResource: CL:0000784][accessDate: 05-04-2011] IPC IPC[accessedResource: CL:0000784][accessDate: 05-04-2011] James Malone T-associated plasma cell T-associated plasma cell[accessedResource: CL:0000784][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000655 interferon-producing cell interferon-producing cell[accessedResource: CL:0000784][accessDate: 05-04-2011] lymphoid dendritic cell lymphoid dendritic cell[accessedResource: CL:0000784][accessDate: 05-04-2011] pDC pDC[accessedResource: CL:0000784][accessDate: 05-04-2011] plasmacytoid T cell plasmacytoid T cell[accessedResource: CL:0000784][accessDate: 05-04-2011] plasmacytoid monocyte plasmacytoid monocyte[accessedResource: CL:0000784][accessDate: 05-04-2011] mature B cell 721 B lymphoblasts A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen.[accessedResource: CL:0000785][accessDate: 05-04-2011] James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000578 mature B lymphocyte mature B lymphocyte[accessedResource: CL:0000785][accessDate: 05-04-2011] mature B-cell mature B-cell[accessedResource: CL:0000785][accessDate: 05-04-2011] mature B-lymphocyte mature B-lymphocyte[accessedResource: CL:0000785][accessDate: 05-04-2011] plasma cell A terminally differentiated cell of the B lymphocyte lineage that produces antibodies; plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern. A terminally differentiated cell of the B lymphocyte lineage that produces antibodies; plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern.[accessedResource: BTO:0000392][accessDate: 05-04-2011] A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin. A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.[accessedResource: CL:0000786][accessDate: 05-04-2011] BTO:0000392 James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000654 plasmacyte plasmacyte[accessedResource: CL:0000786][accessDate: 05-04-2011] plasmocyte memory B cell naive B cell alpha-beta T cell immature alpha-beta T cell mature alpha-beta T cell CD4-positive, CD25-positive, alpha-beta regulatory T cell CD4-positive, alpha-beta intraepithelial T cell CD8-positive, alpha-beta cytotoxic T cell CD8-positive, alpha-beta regulatory T cell CD8-alpha-beta-positive, alpha-beta intraepithelial T cell alpha-beta intraepithelial T cell gamma-delta T cell immature gamma-delta T cell mature gamma-delta T cell gamma-delta intraepithelial T cell CD8-alpha alpha positive, gamma-delta intraepithelial T cell CD4-negative CD8-negative gamma-delta intraepithelial T cell immature single positive thymocyte DN2 thymocyte DN3 thymocyte DN4 thymocyte double-positive, alpha-beta thymocyte A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors. A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors.[accessedResource: CL:0000809][accessDate: 05-04-2011] DP cell DP cell[accessedResource: CL:0000809][accessDate: 05-04-2011] DP thymocyte James Malone Tomasz Adamusiak double-positive, alpha-beta immature T lymphocyte double-positive, alpha-beta immature T lymphocyte[accessedResource: CL:0000809][accessDate: 05-04-2011] double-positive, alpha-beta thymocyte double-positive, alpha-beta thymocyte[accessedResource: CL:0000809][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000171 nontransformed thymocyte CD4-positive, alpha-beta thymocyte CD8-positive, alpha-beta thymocyte memory T cell A T-cell that bears receptors for a specific foreign antigen encountered during a prior infection or vaccination. After an infection or a vaccination, some of the T-cells that participated in the response remain as memory T-cells, which can rapidly mobilize and clone themselves should the same antigen be re-encountered during a second infection at a later time. A T-cell that bears receptors for a specific foreign antigen encountered during a prior infection or vaccination. After an infection or a vaccination, some of the T-cells that participated in the response remain as memory T-cells, which can rapidly mobilize and clone themselves should the same antigen be re-encountered during a second infection at a later time.[accessedResource: BTO:0003435][accessDate: 05-04-2011] A distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive. A distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.[accessedResource: CL:0000813][accessDate: 05-04-2011] BTO:0003435 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002438 memory T cell memory T cell[accessedResource: CL:0000813][accessDate: 05-04-2011] memory T lymphocyte memory T lymphocyte[accessedResource: CL:0000813][accessDate: 05-04-2011] memory T-lymphocyte memory T-lymphocyte[accessedResource: CL:0000813][accessDate: 05-04-2011] mature NK T cell regulatory T cell A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.[accessedResource: CL:0000815][accessDate: 05-04-2011] James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000680 pancreatic T regulatory cell regulatory T cell regulatory T cell[accessedResource: CL:0000815][accessDate: 05-04-2011] regulatory T lymphocyte regulatory T lymphocyte[accessedResource: CL:0000815][accessDate: 05-04-2011] regulatory T-cell regulatory T-lymphocyte regulatory T-lymphocyte[accessedResource: CL:0000815][accessDate: 05-04-2011] suppressor T-cell suppressor T-lymphocyte immature B cell An immature B cell is a precursor B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation. An immature B cell is a precursor B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation.[accessedResource: CL:0000816][accessDate: 05-04-2011] James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000539 immature B lymphocyte immature B lymphocyte[accessedResource: CL:0000816][accessDate: 05-04-2011] immature B-cell immature B-cell[accessedResource: CL:0000816][accessDate: 05-04-2011] immature B-lymphocyte immature B-lymphocyte[accessedResource: CL:0000816][accessDate: 05-04-2011] newly formed B Cell newly formed B Cell[accessedResource: CL:0000816][accessDate: 05-04-2011] precursor B cell A precursor B cell is a B cell with the phenotype CD10-positive (P08473/NEP_HUMAN; PIRSF001194). A precursor B cell is a B cell with the phenotype CD10-positive. A precursor B cell is a B cell with the phenotype CD10-positive.[accessedResource: CL:0000817][accessDate: 05-04-2011] B-cell precursor James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000667 pre-B cell pre-BI cell precursor B cell precursor B cell[accessedResource: CL:0000817][accessDate: 05-04-2011] transitional stage B cell B-1 B cell B-1a B cell B-1b B cell B-2 B cell A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative. A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative.[accessedResource: CL:0000822][accessDate: 05-04-2011] B-0 B cell B-2 B lymphocyte B-2 B lymphocyte[accessedResource: CL:0000822][accessDate: 05-04-2011] B-2 B-cell B-2 B-cell[accessedResource: CL:0000822][accessDate: 05-04-2011] B-2 B-lymphocyte B-2 B-lymphocyte[accessedResource: CL:0000822][accessDate: 05-04-2011] James Malone Tomasz Adamusiak follicular B cell http://www.ebi.ac.uk/efo/EFO_0000092 large pre-BII cell small pre-BII cell immature natural killer cell mature natural killer cell pro-NK cell pro-B cell pro-T cell thromboblast basophilic myeloblast basophilic promyelocyte mast cell progenitor eosinophilic myeloblast eosinophilic promyelocyte neutrophil progenitor cell myeloblast promyelocyte hematopoietic multipotent progenitor cell A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.[accessedResource: CL:0000837][accessDate: 05-04-2011] A progenitor cell of any hematopoietic lineage, potentially multipotent. Jie Zheng MPP MPP[accessedResource: CL:0000837][accessDate: 05-04-2011] Tomasz Adamusiak hematopoietic multipotent progenitor cell hematopoietic multipotent progenitor cell[accessedResource: CL:0000837][accessDate: 05-04-2011] hematopoietic progenitor cell hemopoietic progenitor cell hemopoietic progenitor cell[accessedResource: CL:0000837][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002532 lymphoid lineage restricted progenitor cell myeloid lineage restricted progenitor cell A progenitor cell of any myeloid lineage, potentially multipotent. A progenitor cell restricted to the myeloid lineage. A progenitor cell restricted to the myeloid lineage.[accessedResource: CL:0000839][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002441 myeloid lineage restricted progenitor cell myeloid lineage restricted progenitor cell[accessedResource: CL:0000839][accessDate: 05-04-2011] myeloid progenitor cell immature conventional dendritic cell mature conventional dendritic cell mononuclear cell A cell having only one nucleus, especially: MONOCYTE. A cell having only one nucleus, especially: MONOCYTE.[accessedResource: BTO:0000878][accessDate: 05-04-2011] A leukocyte with a single non-segmented nucleus in the mature form. A leukocyte with a single non-segmented nucleus in the mature form.[accessedResource: CL:0000842][accessDate: 05-04-2011] BTO:0000878 James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000594 peripheral blood mononuclear cell follicular B cell germinal center B cell marginal zone B cell classical monocyte elicited macrophage suppressor macrophage inflammatory macrophage tissue-resident macrophage gastrointestinal tract (lamina propria) macrophage thymic macrophage secondary lymphoid organ macrophage lymph node macrophage tonsillar macrophage Peyer's patch macrophage splenic macrophage splenic marginal zone macrophage splenic metallophillic macrophage splenic red pulp macrophage non-classical monocyte splenic white pulp macrophage splenic tingible body macrophage central nervous system macrophage meningeal macrophage choroid-plexus macrophage perivascular macrophage thymic medullary macrophage thymic cortical macrophage mucosa-associated lymphoid tissue macrophage gut-associated lymphoid tissue macrophage nasal and broncial associated lymphoid tissue macrophage lymph node subcapsular sinus macrophage lymph node tingible body macrophage myeloid suppressor cell alternatively activated macrophage thymocyte A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.[accessedResource: CL:0000084][accessDate: 05-04-2011] An immature T cell located in the thymus. An immature T cell located in the thymus.[accessedResource: CL:0000893][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002449 immature T lymphocyte immature T-cell mature T cell thymic lymphocyte thymic lymphocyte[accessedResource: CL:0000893][accessDate: 05-04-2011] DN1 thymic pro-T cell naive thymus-derived CD4-positive, alpha-beta T cell activated CD4-positive, alpha-beta T cell CD4-positive, alpha-beta memory T cell naive T cell T-helper 17 cell naive thymus-derived CD8-positive, alpha-beta T cell Tr1 cell induced T-regulatory cell natural T-regulatory cell central memory CD4-positive, alpha-beta T cell effector memory CD4-positive, alpha-beta T cell activated CD8-positive, alpha-beta T cell central memory CD8 positive, alpha-beta T cell CD8-positive, alpha-beta cytokine secreting effector T cell CD8-positive, alpha-beta memory T cell cytotoxic T cell effector T cell helper T cell effector memory CD8-positive, alpha-beta T cell immature NK T cell CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell dendritic epidermal T cell Tc1 cell Tc2 cell CD8-positive, CD25-positive, alpha-beta regulatory T cell CD8-positive, CD28-negative, alpha-beta regulatory T cell type I NK T cell type II NK T cell CD4-positive type I NK T cell CD4-negative, CD8-negative type I NK T cell activated CD4-positive type I NK T cell CD4-positive type I NK T cell secreting interferon-gamma CD4-positive type I NK T cell secreting interleukin-4 activated CD4-negative, CD8-negative type I NK T cell CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma CD4-negative, CD8-negative type I NK T cell secreting interleukin-4 activated type II NK T cell type II NK T cell secreting interferon-gamma type II NK T cell secreting interleukin-4 CD4-positive, alpha-beta cytotoxic T cell CD4-negative, CD8-negative, alpha-beta intraepithelial T cell early lymphoid progenitor pre-natural killer cell CD56-bright cytokine secreting natural killer cell cytotoxic CD56-dim natural killer cell mucosal invariant T cell thymic conventional dendritic cell thymic plasmacytoid dendritic cell Be1 Cell Be2 cell lymphocyte of B lineage antibody secreting cell IgE plasma cell IgE memory B cell IgD plasmablast IgE plasmablast IgE short lived plasma cell preBCR-positive large pre-B-II cell preBCR-negative large pre-B-II cell small pre-B-II cell pre-B-II cell pre-B-I cell large pre-B-II cell T1 B cell T2 B cell T3 B cell Bm1 B cell Bm2 B cell Bm3-delta B cell Bm2' B cell Bm3 B cell Bm4 B cell Bm5 B cell Be cell regulatory B cell unswitched memory B cell IgM memory B cell class switched memory B cell IgA memory B cell long lived plasma cell short lived plasma cell IgA short lived plasma cell IgG short lived plasma cell IgM short lived plasma cell IgG memory B cell plasmablast double negative memory B cell IgG plasmablast IgM plasmablast IgA plasmablast IgG plasma cell IgM plasma cell IgA plasma cell hematopoietic cell A blood cell. A blood cell.[accessedResource: BTO:0000574][accessDate: 05-04-2011] A cell found predominately in the blood. A cell found predominately in the blood.[accessedResource: CL:0000081][accessDate: 05-04-2011] A cell of a hematopoietic lineage. A cell of a hematopoietic lineage.[accessedResource: CL:0000988][accessDate: 05-04-2011] BTO:0000574 Tomasz Adamusiak blood cell blood cell[accessedResource: CL:0000081][accessDate: 05-04-2011] haematopoietic cell haematopoietic cell[accessedResource: CL:0000988][accessDate: 05-04-2011] haemopoietic cell haemopoietic cell[accessedResource: CL:0000988][accessDate: 05-04-2011] hemopoietic cell hemopoietic cell[accessedResource: CL:0000988][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002436 CD11c-low plasmacytoid dendritic cell conventional dendritic cell CD11c-negative plasmacytoid dendritic cell immature CD11c-low plasmacytoid dendritic cell mature CD11c-low plasmacytoid dendritic cell immature CD11c-negative plasmacytoid dendritic cell CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor mature CD11c-negative plasmacytoid dendritic cell immature CD8_alpha-negative CD11b-positive dendritic cell CD8_alpha-negative CD11b-negative dendritic cell CD4-positive CD11b-positive dendritic cell CD8_alpha-positive CD11b-negative dendritic cell immature CD8_alpha-negative CD11b-negative dendritic cell mature CD8_alpha-negative CD11b-negative dendritic cell mature CD8_alpha-negative CD11b-positive dendritic cell immature CD8_alpha-positive CD11b-negative dendritic cell mature CD8_alpha-positive CD11b-negative dendritic cell dermal dendritic cell interstitial dendritic cell Kit and Sca1-positive hematopoietic stem cell immature dermal dendritic cell mature dermal dendritic cell immature interstitial dendritic cell CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor mature interstitial dendritic cell CD1a-positive Langerhans cell CD8_alpha-low Langerhans cell immature CD1a-positive Langerhans cell mature CD1a-positive Langerhans cell immature CD8_alpha-low Langerhans cell CD115-positive monocyte OR common dendritic progenitor mature CD8_alpha-low Langerhans cell CD34-positive, CD38-positive common lymphoid progenitor CD115-positive monocyte Kit-positive, CD34-positive common myeloid progenitor CD34-positive, CD38-negative hematopoietic stem cell Kit-positive, Sca1-positive common lymphoid progenitor CD34-positive, CD38-positive common myeloid progenitor CD7-negative lymphoid progenitor cell CD7-positive lymphoid progenitor cell common dendritic progenitor CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor Kit-positive erythroid progenitor cell CD34-positive, CD38-positive granulocyte monocyte progenitor Kit-positive granulocyte monocyte progenitor CD34-positive, GlyA-negative erythroid progenitor cell CD34-negative, GlyA-negative proerythroblast CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell Kit-low, CD34-positive eosinophil progenitor cell CD34-positive, CD38-positive eosinophil progenitor cell macrophage dendritic cell progenitor pre-conventional dendritic cell Kit-positive macrophage dendritic cell progenitor Kit-low proerythroblast GlyA-positive basophillic erythroblast Kit-negative, Ly-76 high basophilic erythroblast Kit-negative, Ly-76 high polychromatophilic erythroblast CD71-low, GlyA-positive polychromatic erythroblast Kit-negative, Ly-76 high orthochromatophilic erythroblasts CD71-negative, GlyA-positive orthochromatic erythroblast Ly-76 high reticulocyte GlyA-positive reticulocytes GlyA-positive erythrocyte Ly-76 high positive erythrocyte CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell Kit-positive megakaryocyte progenitor cell CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell CD34-negative, CD41-positive, CD42-positive megakaryocyte cell CD9-positive, CD41-positive megakaryocyte cell basophil mast progenitor cell Fc-epsilon RIalpha-low mast cell progenitor Fc-epsilon RIalpha-high basophil progenitor cell hematopoietic lineage restricted progenitor cell hematopoietic oligopotent progenitor cell short term hematopoietic stem cell long term hematopoietic stem cell Slamf1-negative multipotent progenitor cell Slamf1-positive multipotent progenitor cell CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell T follicular helper cell immature NK T cell stage I immature NK T cell stage II immature NK T cell stage III immature NK T cell stage IV CD34-positive, CD38-negative multipotent progenitor cell Kit-positive, integrin beta7-high basophil mast progenitor cell Fraction A pre-pro B cell Early pro-B cell Fraction B precursor B cell late pro-B cell Fraction C precursor B cell Fraction C' precursor B cell CD38-high pre-BCR positive cell Fraction D precursor B cell CD22-positive, CD38-low small pre-B cell Fraction E immature B cell CD38-negative immature B cell Fraction F mature B cell CD14-positive, CD16-negative classical monocyte Gr1-low non-classical monocyte CD8alpha-positive thymic conventional dendritic cell melanophage T-helper 9 cell nongranular leukocyte nuocyte CD38-positive naive B cell CD38-negative naive B cell IgG-positive double negative memory B cell IgG-negative double negative memory B cell CD38-positive IgG memory B cell IgD-positive CD38-positive IgG memory B cell IgD-negative CD38-positive IgG memory B cell CD38-negative IgG memory B cell B220-positive CD38-positive naive B cell B220-low CD38-positive naive B cell CD38-negative unswitched memory B cell B220-positive CD38-negative unswitched memory B cell B220-low CD38-negative unswitched memory B cell CD38-positive unswitched memory B cell B220-positive CD38-positive unswitched memory B cell B220-low CD38-positive unswitched memory B cell IgG-negative class switched memory B cell CD38-negative IgG-negative class switched memory B cell CD38-positive IgG-negative class switched memory B cell CD24-positive CD38-negative IgG-negative class switched memory B cell CD24-negative CD38-negative IgG-negative class switched memory B cell B220-positive CD38-positive IgG-negative class switched memory B cell B220-low CD38-positive IgG-negative class switched memory B cell CD27-positive gamma-delta T cell CD27-negative gamma-delta T cell CD25-positive, CD27-positive immature gamma-delta T cell innate effector T cell Tc17 cell epitheloid cell late promyelocyte early promyelocyte echinocyte granulocytopoietic cell metamyelocyte myelocyte A cell derived from a promyelocyte. It differentiates into a metamyelocyte. It has a diameter of 10-18 micrometer, and an oval or round nucleus with finely granulated chromatin. A cell derived from a promyelocyte. It differentiates into a metamyelocyte. It has a diameter of 10-18 micrometer, and an oval or round nucleus with finely granulated chromatin.[accessedResource: NCIt:C13115][accessDate: 05-04-2011] A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses. A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses.[accessedResource: CL:0002193][accessDate: 05-04-2011] Jie Zheng NCIt:C13115 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002535 monopoietic cell immature dendritic epithelial T cell precursor peripheral blood stem cell pleural macrophage periperhal blood mesothelial cell embryonic cell A cell of the embryo. A cell of the embryo.[accessedResource: CL:0002321][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002964 embryonic stem cell BTO:0001086 ES cell James Malone Tomasz Adamusiak Totipotent cell cultured from early embryo. Have the advantage that following modification in vitrothey can be used to produce chimeric embryos and thus transgenic animals. Totipotent cell cultured from early embryo. Have the advantage that following modification in vitrothey can be used to produce chimeric embryos and thus transgenic animals.[accessedResource: BTO:0001086][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000462 preadipocyte A precursor to an adipocyte. A precursor to an adipocyte.[accessedResource: BTO:0001107][accessDate: 05-04-2011] An undifferentiated fibroblast that can be stimulated to form a fat cell. An undifferentiated fibroblast that can be stimulated to form a fat cell.[accessedResource: CL:0002334][accessDate: 05-04-2011] BTO:0001107 James Malone Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002002 CD56-positive, CD161-positive immature natural killer cell decidual natural killer cell CD56-negative, CD161-positive immature natural killer cell CD27-low, CD11b-low immature natural killer cell Dx5-negative, NK1.1-positive immature natural killer cell CD27-high, CD11b-high natural killer cell CD27-low, CD11b-high natural killer cell CD27-high, CD11b-low natural killer cell progenitor cell of endocrine pancreas A multi-fate stem cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1.[accessedResource: CL:0002351][accessDate: 05-04-2011] A multi-fate stem cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1. Jie Zheng Tomasz Adamusiak http://en.wikipedia.org/wiki/Pancreas http://www.ebi.ac.uk/efo/EFO_0002536 pancreatic endocrine progenitor pancreatic endocrine progenitor[accessedResource: CL:0002351][accessDate: 05-04-2011] pancreatic islet progenitor cell pancreatic islet progenitor cell[accessedResource: CL:0002351][accessDate: 05-04-2011] gestational hematopoietic stem cell fetal liver hematopoietic progenitor cell A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative. A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative.[accessedResource: CL:0002353][accessDate: 05-04-2011] Jie Zheng Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002533 similar to CL:0000837, but in fetal liver yolk sac hematopoietic stem cell primitive red blood cell primitive reticulocyte fetal derived definitive erythrocyte pyrenocyte placental hematopoietic stem cell AGM hematopoietic stem cell primitive erythroid progenitor keratocyte A keratocyte is a specialized fibroblast residing in the stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate. A keratocyte is a specialized fibroblast residing in the stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate. A keratocyte is a specialized fibroblast residing in the stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate.[accessedResource: CL:0002363][accessDate: 05-04-2011] Ele Holloway James Malone Tomasz Adamusiak corneal fibroblast corneal fibroblast[accessedResource: CL:0002363][accessDate: 05-04-2011] corneal keratocyte corneal keratocyte[accessedResource: CL:0002363][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0002479 medullary thymic epithelial cell An epithelial cell located in the inner portion of the thymus where the T lymphocytes become mature and are released into the circulation. An epithelial cell located in the inner portion of the thymus where the T lymphocytes become mature and are released into the circulation.[accessedResource: NCIt:C45702][accessDate: 05-04-2011] An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output. An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output.[accessedResource: CL:0002365][accessDate: 05-04-2011] James Malone NCIt:C45702 Thymic Medullary Epithelial Cell Thymic Medullary Epithelial Cell[accessedResource: NCIt:C45702][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000581 mTEC mTEC[accessedResource: CL:0002365][accessDate: 05-04-2011] airway epithelial cell An endo-epithelial cell of the respiratory tract. An endo-epithelial cell of the respiratory tract.[accessedResource: CL:0002368][accessDate: 05-04-2011] BTO:0000419 Epithelium of the respiratory portion of the bronchial tree. Epithelium of the respiratory portion of the bronchial tree.[accessedResource: BTO:0000419][accessDate: 05-04-2011] Tomasz Adamusiak airway epithelium http://www.ebi.ac.uk/efo/EFO_0003031 respiratory epithelial cell respiratory epithelial cell[accessedResource: CL:0002368][accessDate: 05-04-2011] respiratory epithelium respiratory epithelium[accessedResource: BTO:0000419][accessDate: 05-04-2011] somatic cell A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell).[accessedResource: CL:0002371][accessDate: 05-04-2011] BTO:0001268 James Malone NCIt:C12949 One of the cells of the body that compose the tissues, organs, and parts of that individual other than the germ cells. One of the cells of the body that compose the tissues, organs, and parts of that individual other than the germ cells.[accessedResource: BTO:0001268][accessDate: 05-04-2011] Somatic Cells Somatic Cells[accessedResource: NCIt:C12949][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0000704 immature Vgamma2-positive fetal thymocyte intermediate monocyte CD141-positive myeloid dendritic cell Gr1-high classical monocyte CD14-low, CD16-positive monocyte CD14-positive, CD16-positive monocyte Gr1-positive, CD43-positive monocyte CD1c-positive myeloid dendritic cell Fraction B/C precursor B cell mature dendritic epithelial T cell precursor Peyer's patch B cell mature Vgamma2-positive fetal thymocyte fetal thymocyte gamma-delta thymocyte immature Vgamma2-positive thymocyte mature Vgamma2-positive thymocyte immature Vgamma2-negative thymocyte mature Vgamma2-negative thymocyte Vgamma1.1-positive, Vdelta6.3-negative thymocyte Vgamma1.1-positive, Vdelta6.3-positive thymocyte mature Vgamma1.1-positive, Vdelta6.3-negative thymocyte immature Vgamma1.1-positive, Vdelta6.3-negative thymocyte immature Vgamma1.1-positive, Vdelta6.3-positive thymocyte mature Vgamma1.1-positive, Vdelta6.3-positive thymocyte primitive erythroid lineage cell mature T cell immature T cell nucleated reticulocyte enucleated reticulocyte DN2a thymocyte DN2b thymocyte early T lineage precursor CD11b-positive, CD27-positive natural killer cell resting double-positive thymocyte double-positive blast CD69-positive double-positive thymocyte CD4-intermediate, CD8-positive double-positive thymocyte CD4-positive, CD8-intermediate double-positive thymocyte CD24-positive, CD4 single-positive thymocyte CD69-positive, CD4-positive single-positive thymocyte CD24-positive, CD8 single-positive thymocyte CD69-positive, CD8-positive single-positive thymocyte mature CD4 single-positive thymocyte mature CD8 single-positive thymocyte NK1.1-positive natural killer cell NKGA2-positive natural killer cell Ly49D-positive natural killer cell CD94-positive natural killer cell CD94-negative, Ly49CI-negative natural killer cell Ly49CI-positive natural killer cell Ly49H-positive natural killer cell Ly49D-negative natural killer cell Ly49CI-negative natural killer cell CD94-negative natural killer cell Ly49H-negative natural killer cell CD94-positive Ly49CI-positive natural killer cell Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell CD8_alpha-negative plasmactyoid dendritic cell CD8_alpha-positive plasmactyoid dendritic cell epidermal Langerhans cell langerin-positive dermal dendritic cell langerin-negative dermal dendritic cell CD8alpha-negative thymic conventional dendritic cell CD103-positive dendritic cell adipose dendritic cell SIRPa-positive adipose dendritic cell SIRPa-negative adipose dendritic cell CD11b-positive dendritic cell small intestine serosal dendritic cell Gr1-high myeloid suppressor cell Gr1-low myeloid suppressor cell MHC-II-negative classical monocyte MHC-II-positive classical monocyte MHC-II-negative non-classical monocyte MHC-II-low non-classical monocyte MHC-II-high non-classical monocyte lymphoid MHC-II-negative classical monocyte lymphoid MHC-II-negative non-classical monocyte bone marrow macrophage adipose macrophage F4/80-negative adipose macrophage F4/80-positive adipose macrophage double negative thymocyte intraepithelial lymphocyte liver CD103-negative dendritic cell liver CD103-positive dendritic cell langerin-positive lymph node dendritic cell langerin-negative, CD103-negative lymph node dendritic cell CD103-positive, langerin-positive lymph node dendritic cell CD103-negative, langerin-positive lymph node dendritic cell CD11b-low, CD103-negative, langerin-negative lymph node dendritic cell CD11b-high, CD103-negative, langerin-negative lymph node dendritic cell Vgamma5-positive CD8alpha alpha positive gamma-delta intraepithelial T cell Vgamma5-negative CD8alpha alpha positive gamma-delta intraepithelial T cell CD14-positive dermal dendritic cell immature CD14-positive dermal dendritic cell mature CD14-positive dermal dendritic cell CD1a-positive dermal dendritic cell immature CD1a-positive dermal dendritic cell mature CD1a-positive dermal dendritic cell CD16-positive myeloid dendritic cell immature CD16-positive myeloid dendritic cell mature CD16-positive myeloid dendritic cell metabolic process Dani Welter GO:0008152 The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. metabolism true molecular function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. GO curators RNA interference The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. RNAi GO curators estrogen receptor activity Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function. progesterone receptor binding Interacting selectively and non-covalently with a progesterone receptor. signaling receptor activity Receiving a signal and transmitting the signal in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. Mus James Malone Mus (commonly mice) is a small mammal belonging to the order of rodents. http://www.ebi.ac.uk/efo/EFO_0002644 mice mouse Mus caroli James Malone Ryukyu mouse http://www.ebi.ac.uk/efo/EFO_0002645 Mus musculus James Malone house mouse http://www.ebi.ac.uk/efo/EFO_0001993 Mus musculus castaneus James Malone Mus castaneus Mus casteneus Mus musculus castenus http://www.ebi.ac.uk/efo/EFO_0002646 southeast Asian house mouse southeastern Asian house mouse Mus musculus domesticus James Malone Mus domesticus http://www.ebi.ac.uk/efo/EFO_0002647 western European house mouse Mus spretus Algerian Mouse James Malone http://www.ebi.ac.uk/efo/EFO_0002649 Rattus Mammals, Rats NIFSTD:birnlex_160 Rat[accessedResource: NIFSTD:birnlex_160][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001995 rat Rattus norvegicus BN Gunn rats James Malone Norway rat Rattus norvegicus, commonly Brown or Norway rat, is a rat strain as described in http://www.informatics.jax.org/external/festing/rat/docs/BN.shtml Rattus norvegicus8 Rattus norwegicus Rattus rattiscus Rattus sp. strain Wistar brown rat common rat http://www.ebi.ac.uk/efo/EFO_0000104 http://www.informatics.jax.org/external/festing/rat/docs/BN.shtml rat rats Rattus rattus James Malone black rat house rat http://www.ebi.ac.uk/efo/EFO_0002654 roof rat Virus Animal Virus Animal Virus[accessedResource: MSH:D014780][accessDate: 05-04-2011] Animal Viruses Animal Viruses[accessedResource: MSH:D014780][accessDate: 05-04-2011] James Malone Jie Zheng MO_372 MSH:D014780 Minute infectious agents whose genomes are composed of DNA or RNA, but not both. They are characterized by a lack of independent metabolism and the inability to replicate outside living host cells. Minute infectious agents whose genomes are composed of DNA or RNA, but not both. They are characterized by a lack of independent metabolism and the inability to replicate outside living host cells.[accessedResource: MSH:D014780][accessDate: 05-04-2011] Tomasz Adamusiak Virus, Animal Virus, Animal[accessedResource: MSH:D014780][accessDate: 05-04-2011] Viruses Viruses, Animal Viruses, Animal[accessedResource: MSH:D014780][accessDate: 05-04-2011] Viruses[accessedResource: MSH:D014780][accessDate: 05-04-2011] Zoophaginae Zoophaginae[accessedResource: MSH:D014780][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#virus http://www.ebi.ac.uk/efo/EFO_0001450 Oscheius tipulae Bacteria James Malone http://www.ebi.ac.uk/efo/EFO_0001448 Archaea James Malone http://www.ebi.ac.uk/efo/EFO_0001447 Eukaryota Eucaryotae Eucaryotae[accessedResource: NIFSTD:birnlex_399][accessDate: 05-04-2011] Eukarya Eukarya[accessedResource: NIFSTD:birnlex_399][accessDate: 05-04-2011] James Malone NIFSTD:birnlex_399 Tomasz Adamusiak eucaryotes eucaryotes[accessedResource: NIFSTD:birnlex_399][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0001449 Oscheius myriophila 972h- 972h- is a yeast strain as described in article PMID 12753 EFO_0000739 James Malone PMID: 12753 Caenorhabditis remanei Viridiplantae James Malone Viridiplantae are a clade comprising the green algae and land plants. green plants http://www.ebi.ac.uk/efo/EFO_0002633 Arabidopsis thaliana James Malone Strain or line specific to Arabidopsis thaliana. Brassica oleracea Brassica oleracea, commonly called Wild Mustard, is a species of Brassica native to coastal southern and western Europe, where its tolerance of salt and lime and its intolerance of competition from other plants typically restrict its natural occurrence to limestone sea cliffs, like the chalk cliffs on both sides of the English Channel. James Malone http://en.wikipedia.org/wiki/Brassica_oleracea http://www.ebi.ac.uk/efo/EFO_0002635 Mus musculus musculus James Malone Mus musculus hortulanus eastern European house mouse http://www.ebi.ac.uk/efo/EFO_0002648 Rhabditis remanei Oscheius dolichura Ascomycota EFO_0000740 James Malone Strain or line specific to yeast yeasts Schizosaccharomyces pombe James Malone S. pombe fission yeast http://www.ebi.ac.uk/efo/EFO_0002656 Saccharomyces cerevisiae James Malone baker's yeast http://www.ebi.ac.uk/efo/EFO_0002655 Rhabditinae Caenorhabditis Caenorhabditis briggsae C. briggsae Caenorhabditis elegans C. elegans Caenorhabditis elegans is a free-living, transparent nematode (roundworm), about 1 mm in length, which lives in temperate soil environments James Malone http://www.ebi.ac.uk/efo/EFO_0002636 Drosophila melanogaster NIFSTD:birnlex_535 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002036 Drosophila simulans Helen Parkinson Danio rerio James Malone http://www.ebi.ac.uk/efo/EFO_0002639 zebrafish Gallus gallus James Malone chicken http://www.ebi.ac.uk/efo/EFO_0002640 red junglefowl Chlorocebus aethiops African green monkey James Malone The Grivet (Chlorocebus aethiops) is an Old World monkey with long white tufts of hair along the sides of the face. grivet http://en.wikipedia.org/wiki/Grivet http://www.ebi.ac.uk/efo/EFO_0002638 Macaca fascicularis James Malone The Crab-eating Macaque (Macaca fascicularis) is a primarily arboreal macaque native to Southeast Asia. crab-eating macaque http://www.ebi.ac.uk/efo/EFO_0002642 long-tailed macaque Macaca mulatta James Malone Rhesus Macaque The Rhesus Macaque (Macaca mulatta), often called the Rhesus Monkey, is one of the best known species of Old World monkeys. http://en.wikipedia.org/wiki/Rhesus_Macaque http://www.ebi.ac.uk/efo/EFO_0002643 Papio anubis James Malone Olive Baboon http://www.ebi.ac.uk/efo/EFO_0002652 Gorilla gorilla James Malone Western gorilla http://www.ebi.ac.uk/efo/EFO_0002641 Pan paniscus Bonobo James Malone http://www.ebi.ac.uk/efo/EFO_0002650 pygmy chimpanzee Pan troglodytes Common Chimpanzee James Malone http://www.ebi.ac.uk/efo/EFO_0002651 Pongo pygmaeus Bornean Orangutan James Malone http://www.ebi.ac.uk/efo/EFO_0002653 Homo sapiens Human Human[accessedResource: NIFSTD:birnlex_516][accessDate: 05-04-2011] James Malone NIFSTD:birnlex_516 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001994 Oscheius dolichuroides Bos taurus Bos taurus, commonly named cattle. James Malone cow http://www.ebi.ac.uk/efo/EFO_0002634 Capra hircus James Malone goat http://www.ebi.ac.uk/efo/EFO_0002637 morphology A property of a single physical entity describing the entity's size or shape or structure. Modified from PATO original by James Malone histology mass A physical quality of the amount of matter in a material. James Malone modified from PATO viability alive pre-mortem dead Cardiac Death Cardiac Death[accessedResource: MSH:D003643][accessDate: 05-04-2011] Death Death, Cardiac Death, Cardiac[accessedResource: MSH:D003643][accessDate: 05-04-2011] Death[accessedResource: MSH:D003643][accessDate: 05-04-2011] Determination of Death Determination of Death[accessedResource: MSH:D003643][accessDate: 05-04-2011] Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions. Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.[accessedResource: MSH:D003643][accessDate: 05-04-2011] MSH:D003643 Near-Death Experience Near-Death Experience[accessedResource: MSH:D003643][accessDate: 05-04-2011] Tomasz Adamusiak post-mortem unit A unit of measurement is a standardized quantity of a physical quality. James Malone Jie Zheng MO_3 NIFSTD:birnlex_2015 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001446 length unit A base unit which is a standard measure of the distance between two points. A length unit is a base unit which is a standard measure of the distance between two points. A unit which is a standard measure of the distance between two points. DistanceUnit James Malone Jon Ison UO:0000001 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#DistanceUnit http://www.ebi.ac.uk/efo/EFO_0001678 mass unit A base unit which is a standard measure of the amount of matter/energy of a physical object. A mass unit is a base unit which is a standard measure of the amount of matter/energy of a physical object. A unit which is a standard measure of the amount of matter/energy of a physical object. James Malone Jie Zheng MO_11 MO_149 MassUnit MassUnitOther MassUnitOther[accessedResource: MO_11][accessDate: 05-04-2011] MassUnit[accessedResource: MO_149][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001679 time unit A base unit which is a standard measure of the dimension in which events occur in sequence. A time unit is a base unit which is a standard measure of the dimension in which events occur in sequence. A unit which is a standard measure of the dimension in which events occur in sequence. James Malone Jie Zheng MO_103 MO_166 TimeUnit TimeUnitOther TimeUnitOther[accessedResource: MO_103][accessDate: 05-04-2011] TimeUnit[accessedResource: MO_166][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001680 time derived unit electric current unit A base unit which is a standard measure of the flow of electric charge. A unit which is a standard measure of the flow of electric charge. An electric current unit is a base unit which is a standard measure of the flow of electric charge. James Malone UO:0000004 http://www.ebi.ac.uk/efo/EFO_0001681 temperature unit A base unit which is a standard measure of the average kinetic energy of the particles in a sample of matter. A temperature unit is a base unit which is a standard measure of the average kinetic energy of the particles in a sample of matter. A unit which is a standard measure of the average kinetic energy of the particles in a sample of matter. James Malone Jie Zheng MO_48 TemperatureUnit TemperatureUnit[accessedResource: MO_48][accessDate: 05-04-2011] Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001682 temperature derived unit substance unit A base unit which is a standardized quantity of an element or compound with uniform composition. A substance unit is a base unit which is a standardised quantity of an element or compound with uniform composition. A unit which is a standardised quantity of an element or compound with uniform composition. James Malone UO:0000006 http://www.ebi.ac.uk/efo/EFO_0001683 luminous intensity unit A base unit which is a standard measure of the wavelength-weighted power emitted by a light source in a particular direction. A luminous intensity unit is a base unit which is a standard measure of the wavelength-weighted power emitted by a light source in a particular direction. A unit which is a standard measure of the wavelength-weighted power emitted by a light source in a particular direction. James Malone UO:0000007 http://www.ebi.ac.uk/efo/EFO_0001684 meter A length unit which is equal to the length of the path traveled by light in vacuum during a time interval of 1/299 792 458 of a second. A meter is a length unit which is equal to the length of the path traveled by light in vacuum during a time interval of 1/299 792 458 of a second. James Malone Jie Zheng Jon Ison MO_367 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#m http://www.ebi.ac.uk/efo/EFO_0001685 m m[accessedResource: MO_367][accessDate: 05-04-2011] metre kilogram A kilogram is a mass unit which is equal to the mass of the International Prototype Kilogram kept by the BIPM at Svres, France. A mass unit which is equal to the mass of the International Prototype Kilogram kept by the BIPM at Svres, France. James Malone Jie Zheng Jon Ison MO_846 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#kg http://www.ebi.ac.uk/efo/EFO_0001686 kg kg[accessedResource: MO_846][accessDate: 05-04-2011] second A second is a time unit which is equal to the duration of 9 192 631 770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom. A time unit which is equal to the duration of 9 192 631 770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom. James Malone UO:0000010 http://www.ebi.ac.uk/efo/EFO_0001687 s ampere A An ampere is an electric current unit which is equal to the constant current which, if maintained in two straight parallel conductors of infinite length, of negligible circular cross-section, and placed 1 m apart in vacuum, would produce between these conductors a force equal to 2 x 10^[-7] newton per meter of length. An electric current unit which is equal to the constant current which, if maintained in two straight parallel conductors of infinite length, of negligible circular cross-section, and placed 1 m apart in vacuum, would produce between these conductors a force equal to 2 x 10^[-7] newton per meter of length. James Malone UO:0000011 http://www.ebi.ac.uk/efo/EFO_0001688 kelvin A kelvin is a thermodynamic temperature unit which is equal to the fraction 1/273.16 of the thermodynamic temperature of the triple point of water. A thermodynamic temperature unit which is equal to the fraction 1/273.16 of the thermodynamic temperature of the triple point of water. James Malone Jie Zheng K K[accessedResource: MO_614][accessDate: 05-04-2011] MO_614 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#K http://www.ebi.ac.uk/efo/EFO_0001689 mole A mole is a substance unit which is equal to the amount of substance of a molecular system which contains as many elementary entities as there are atoms in 0.012 kilogram of carbon 12. A substance unit which is equal to the amount of substance of a molecular system which contains as many elementary entities as there are atoms in 0.012 kilogram of carbon 12. James Malone Jie Zheng Jon Ison MO_998 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#mol http://www.ebi.ac.uk/efo/EFO_0001690 mol mol[accessedResource: MO_998][accessDate: 05-04-2011] candela A candela is a luminous intensity unit which equal to the luminous intensity, in a given direction, of a source that emits monochromatic radiation of frequency 540 x 1012 hertz and that has a radiant intensity in that direction of 1/683 watt per steradian. A luminous intensity unit which equal to the luminous intensity, in a given direction, of a source that emits monochromatic radiation of frequency 540 x 1012 hertz and that has a radiant intensity in that direction of 1/683 watt per steradian. James Malone Jie Zheng Jon Ison MO_572 Tomasz Adamusiak candela cd http://mged.sourceforge.net/ontologies/MGEDOntology.owl#candela http://www.ebi.ac.uk/efo/EFO_0001691 centimeter A centimeter is a length unit which is equal to one hundredth of a meter or 10^-2 m. A length unit which is equal to one hundredth of a meter or 10^[-2] m. James Malone Jie Zheng Jon Ison MO_837 Tomasz Adamusiak centimetre cm cm[accessedResource: MO_837][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#cm http://www.ebi.ac.uk/efo/EFO_0001720 millimeter A length unit which is equal to one thousandth of a meter or 10^[-3] m. A millimeter is a length unit which is equal to one thousandth of a meter or 10^-3 m. Jon Ison MO_648 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#DistanceUnit http://www.ebi.ac.uk/efo/EFO_0004361 http://www.ebi.ac.uk/efo/millimeter millimetre mm micrometer A length unit which is equal to one millionth of a meter or 10^[-6] m. A micrometer is a length unit which is equal to 1m x 10^-6. James Malone Jie Zheng Jon Ison MO_421 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#um http://www.ebi.ac.uk/efo/EFO_0001724 micrometre micron um um[accessedResource: MO_421][accessDate: 05-04-2011] µm nanometer A length unit which is equal to one thousandth of one millionth of a meter or 10^[-9] m. A nanometer is a length unit which is equal to 1m x 10^-9. James Malone UO:0000018 http://www.ebi.ac.uk/efo/EFO_0001723 nanometre nm picometer A length unit which is equal to 10^[-12] m. A picometer is a length unit which is equal to 1m x 10^-12. James Malone UO:0000020 http://www.ebi.ac.uk/efo/EFO_0001722 picometre pm gram A gram is a mass unit which is equal to one-thousanth of a kilogram. A mass unit which is equal to one thousandth of a kilogram or 10^[-3] kg. James Malone Jie Zheng Jon Ison MO_825 Tomasz Adamusiak g g[accessedResource: MO_825][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#g http://www.ebi.ac.uk/efo/EFO_0001705 milligram A mass unit which is equal to one thousandth of a gram or 10^[-3] g. A milligram is a mass unit which is equal to one-millionth of a kilogram. James Malone Jie Zheng Jon Ison MO_949 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#mg http://www.ebi.ac.uk/efo/EFO_0001706 mg mg[accessedResource: MO_949][accessDate: 05-04-2011] microgram A mass unit which is equal to one millionth of a gram or 10^[-6] g. A microgram is a mass unit which is equal to 1 gram x 10^-6 James Malone Jie Zheng Jon Ison MO_438 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#ug http://www.ebi.ac.uk/efo/EFO_0001707 ug ug[accessedResource: MO_438][accessDate: 05-04-2011] µg nanogram A mass unit which is equal to one thousandth of one millionth of a gram or 10^[-9] g. A microgram is a mass unit which is equal to 1 gram x 10^-9 James Malone Jie Zheng Jon Ison MO_796 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#ng http://www.ebi.ac.uk/efo/EFO_0001708 ng ng[accessedResource: MO_796][accessDate: 05-04-2011] picogram A mass unit which is equal to one millionth of one millionth of a gram. A picogram is a mass unit which is equal to 1 gram x 10^-12 Jon Ison MO_363 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#pg http://www.ebi.ac.uk/efo/EFO_0004360 pg femtogram A mass unit which is equal to 10^[-15] g. A microgram is a mass unit which is equal to 1 gram x 10^-15 James Malone UO:0000026 fg http://www.ebi.ac.uk/efo/EFO_0001709 degree celsius A temperature derived unit which is equal to one Kelvin degree. However, they have their zeros at different points. The Centigrade scale has its zero at 273.15 K. A temperature unit which is equal to one Kelvin degree. However, they have their zeros at different points. The Centigrade scale has its zero at 273.15 K. C Degree celsius is a temperature derived unit which is equal to one Kelvin degree. However, they have their zeros at different points. The Centigrade scale has its zero at 273.15 K. James Malone Jie Zheng MO_980 Tomasz Adamusiak degree centigrade degrees_C degrees_C[accessedResource: MO_980][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#degrees_C http://www.ebi.ac.uk/efo/EFO_0001700 microsecond A microsecond is a time unit which is equal to one millionth of a second or 10^-6 s. A time unit which is equal to one millionth of a second or 10^[-6] s. James Malone Jie Zheng Jon Ison MO_795 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#us http://www.ebi.ac.uk/efo/EFO_0001792 us us[accessedResource: MO_795][accessDate: 05-04-2011] µs minute A minute is a derived time unit which is equal to 60 seconds. A time unit which is equal to 60 seconds. James Malone UO:0000031 http://www.ebi.ac.uk/efo/EFO_0001791 min hour A time unit which is equal to 3600 seconds or 60 minutes. An hour is a derived time unit which is equal to 3600 seconds or 60 minutes. James Malone UO:0000032 h http://www.ebi.ac.uk/efo/EFO_0001790 day A day is a derived time unit which is equal to 24 hours. A time unit which is equal to 24 hours. James Malone UO:0000033 http://www.ebi.ac.uk/efo/EFO_0001789 week A time unit which is equal to 7 days. A week is a derived time unit which is equal to 7 days. James Malone UO:0000034 http://www.ebi.ac.uk/efo/EFO_0001788 month A month is a derived time unit which is approximately equal to the length of time of one of cycle of the moon's phases which is science is taken to be equal to 30 days. A time unit which is approximately equal to the length of time of one of cycle of the moon's phases which is science is taken to be equal to 30 days. James Malone UO:0000035 http://www.ebi.ac.uk/efo/EFO_0001726 year A time unit which is equal to 12 months which is science is taken to be equal to 365.25 days. A year is a derived time unit which is equal to 365.25 days. James Malone UO:0000036 http://www.ebi.ac.uk/efo/EFO_0001725 micromole A substance unit equal to a millionth of a mol or 10^[-6] mol. James Malone Jie Zheng Jon Ison MO_752 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#umol http://www.ebi.ac.uk/efo/EFO_0001801 umol umol[accessedResource: MO_752][accessDate: 05-04-2011] µmol millimole A millimole is a substance unit equal to a thousandth of a mol or 10^[-3] mol. A substance unit equal to a thousandth of a mol or 10^[-3] mol. James Malone UO:0000040 http://www.ebi.ac.uk/efo/EFO_0001802 mmol nanomole A nanomole is a substance unit equal to one thousandth of one millionth of a mole or 10^-9 mol. A substance unit equal to one thousandth of one millionth of a mole or 10^[-9] mol. James Malone Jie Zheng Jon Ison MO_743 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#nmol http://www.ebi.ac.uk/efo/EFO_0001800 nmol nmol[accessedResource: MO_743][accessDate: 05-04-2011] picomole A picomole is a substance unit equal to 10^-12 mol. A substance unit equal to 10^[-12] mol. James Malone Jie Zheng Jon Ison MO_688 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#pmol http://www.ebi.ac.uk/efo/EFO_0001798 pmol pmol[accessedResource: MO_688][accessDate: 05-04-2011] femtomole A femtomole is a substance unit equal to 10^-15 mol. A substance unit equal to 10^[-15] mol. James Malone Jie Zheng Jon Ison MO_689 Tomasz Adamusiak fmol fmol[accessedResource: MO_689][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#fmol http://www.ebi.ac.uk/efo/EFO_0001797 attomole A substance unit equal to 10^[-18] mol. An attomole is a substance unit equal to 10^-18 mol. James Malone Jie Zheng MO_977 Tomasz Adamusiak amol amol[accessedResource: MO_977][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#amol http://www.ebi.ac.uk/efo/EFO_0001793 base unit A base unit is a unit which is used to measure a paticular type which is independent from all other base units and from which all measures of that type can be derived, for example, a length base unit of the meter. This is akin to the SI base unit system. A unit which is one of a particular measure to which all measures of that type can be related. James Malone UO:0000045 http://www.ebi.ac.uk/efo/EFO_0001677 derived unit A derived unit is a unit which is derived from base units. A unit which is derived from base units. James Malone UO:0000046 http://www.ebi.ac.uk/efo/EFO_0001692 area unit A derived unit which is a standard measure of the amount of a 2-dimensional flat surface. A unit which is a standard measure of the amount of a 2-dimensional flat surface. An area unit is a derived unit which is a standard measure of the amount of a 2-dimensional flat surface. James Malone UO:0000047 http://www.ebi.ac.uk/efo/EFO_0001693 concentration unit A concentration unit is a dervied unit which represents a standard measurement of how much of a given substance there is mixed with another substance. A derived unit which represents a standard measurement of how much of a given substance there is mixed with another substance. A unit which represents a standard measurement of how much of a given substance there is mixed with another substance. ConcentrationUnit ConcentrationUnitOther ConcentrationUnitOther[accessedResource: MO_86][accessDate: 05-04-2011] ConcentrationUnit[accessedResource: MO_61][accessDate: 05-04-2011] James Malone Jie Zheng MO_61 MO_86 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001803 molar mass unit A derived unit which is a standard measure of the mass of a homogeneous substance containing 6.02 x 1023 atoms or molecules. A unit which is a standard measure of the mass of a homogeneous substance containing 6.02 x 1023 atoms or molecules. unit of molarity A concentration unit which is a standard measure of the number of moles of a given substance per liter of solution. A derived concentration unit which is a standard measure of the number of moles of a given substance per liter of solution. A unit of molarity is a derived concentration unit which is a standard measure of the number of moles of a given substance per liter of solution. James Malone UO:0000061 http://www.ebi.ac.uk/efo/EFO_0001804 molar A molar is a unit of molarity which expresses a concentration of 1 mole of solute per liter of solution (mol/L). A unit of concentration which expresses a concentration of 1 mole of solute per liter of solution (mol/L). James Malone Jie Zheng M MO_936 M[accessedResource: MO_936][accessDate: 05-04-2011] Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#M http://www.ebi.ac.uk/efo/EFO_0001805 millimolar A millimolar is a unit of molarity which is equal to one thousandth of a molar or 10^-3 M. A unit of molarity which is equal to one thousandth of a molar or 10^[-3] M. James Malone Jie Zheng MO_509 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#mM http://www.ebi.ac.uk/efo/EFO_0001806 mM mM[accessedResource: MO_509][accessDate: 05-04-2011] micromolar A unit of molarity which is equal to one millionth of a molar or 10^[-6] M. James Malone Jie Zheng MO_740 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#uM http://www.ebi.ac.uk/efo/EFO_0001811 uM uM[accessedResource: MO_740][accessDate: 05-04-2011] µM nanomolar A unit of molarity which is equal to one thousandth of one millionth of a molar or 10^[-9] M. James Malone Jie Zheng MO_862 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#nm http://www.ebi.ac.uk/efo/EFO_0001812 nm nm[accessedResource: MO_862][accessDate: 05-04-2011] picomolar A unit of molarity which is equal to 10^[-12] M. James Malone Jie Zheng MO_628 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#pM http://www.ebi.ac.uk/efo/EFO_0001813 pM pM[accessedResource: MO_628][accessDate: 05-04-2011] femtomolar A unit of molarity which is equal to 10^[-15] M. James Malone Jie Zheng MO_898 Tomasz Adamusiak fM fM[accessedResource: MO_898][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#fM http://www.ebi.ac.uk/efo/EFO_0001814 square meter A square meter is an area unit which is equal to an area enclosed by a square with sides each 1 meter long. An area unit which is equal to an area enclosed by a square with sides each 1 meter long. James Malone UO:0000080 http://www.ebi.ac.uk/efo/EFO_0001694 m^[2] square metre volume unit A derived unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas. A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas. A volume unit is a derived unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas. James Malone Jie Zheng MO_155 MO_179 Tomasz Adamusiak VolumeUnit VolumeUnitOther VolumeUnitOther[accessedResource: MO_155][accessDate: 05-04-2011] VolumeUnit[accessedResource: MO_179][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0001711 cubic centimeter A cubic centimeter is a volume unit which is equal to one millionth of a cubic meter or 10^[-9] m^[3], or to 1 ml. A volume unit which is equal to one millionth of a cubic meter or 10^[-9] m^[3], or to 1 ml. James Malone Jie Zheng Jon Ison MO_834 Tomasz Adamusiak cc cc[accessedResource: MO_834][accessDate: 05-04-2011] cm^3 http://mged.sourceforge.net/ontologies/MGEDOntology.owl#cc http://www.ebi.ac.uk/efo/EFO_0001714 milliliter A milliliter is a volume unit which is equal to one thousandth of a liter or 10^-3 L, or to 1 cubic centimeter. A volume unit which is equal to one thousandth of a liter or 10^[-3] L, or to 1 cubic centimeter. James Malone Jie Zheng Jon Ison MO_488 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#ml http://www.ebi.ac.uk/efo/EFO_0001712 ml ml[accessedResource: MO_488][accessDate: 05-04-2011] liter A liter is a volume unit which is equal to one thousandth of a cubic meter or 10^-3 m^3, or to 1 decimeter. A volume unit which is equal to one thousandth of a cubic meter or 10^[-3] m^[3], or to 1 decimeter. James Malone Jie Zheng Jon Ison L[accessedResource: MO_444][accessDate: 05-04-2011] MO_444 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#L http://www.ebi.ac.uk/efo/EFO_0001713 l microliter A microliter is a volume unit which is equal to one millionth of a liter or 10^-6 L. A volume unit which is equal to one millionth of a liter or 10^[-6] L. James Malone Jie Zheng Jon Ison MO_926 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#ul http://www.ebi.ac.uk/efo/EFO_0001717 ul ul[accessedResource: MO_926][accessDate: 05-04-2011] µl nanoliter A nanoliter is a volume unit which is equal to one thousandth of one millionth of a liter or 10^-9 L. A volume unit which is equal to one thousandth of one millionth of a liter or 10^[-9] L. James Malone Jie Zheng Jon Ison MO_754 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#nl http://www.ebi.ac.uk/efo/EFO_0001704 nl nl[accessedResource: MO_754][accessDate: 05-04-2011] picoliter A picoliter is a volume unit which is equal to 10^-12 L. A volume unit which is equal to 10^[-12] L. James Malone Jie Zheng Jon Ison MO_905 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#pl http://www.ebi.ac.uk/efo/EFO_0001718 pl pl[accessedResource: MO_905][accessDate: 05-04-2011] true femtoliter A femtoliter is a volume unit which is equal to 10^-15 L. A volume unit which is equal to 10^[-12] L. James Malone Jie Zheng Jon Ison MO_721 Tomasz Adamusiak fl fl[accessedResource: MO_721][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#fl http://www.ebi.ac.uk/efo/EFO_0001719 derived temperature unit A derived unit which represents a standard measurement of temperature in a particular temperature scale. A dervied temperature unit is a derived unit which represents a standard measurement of temperature in a particular temperature scale. A unit which is a standard measure of the average kinetic energy of the particles in a sample of matter. James Malone UO:0000126 http://www.ebi.ac.uk/efo/EFO_0001699 temperature derived unit temperature unit radiation unit A derived unit which is a standard measure of the amount of radiation emitted by a given radiation source as well as the amount of radiation absorbed or deposited in a specific material by a radiation source. A unit which is a standard measure of the amount of radiation emitted by a given radiation source as well as the amount of radiation absorbed or deposited in a specific material by a radiation source. absorbed dose unit A derived unit which is a standard measure of the energy imparted by ionizing radiation to unit mass of matter such as tissue. A unit which is a standard measure of the energy imparted by ionizing radiation to unit mass of matter such as tissue. absorbed dose unit Gray An absorbed dose unit which is equal to the absorption of one joule of radiation energy by one kilogram of matter. Gy derived time unit A derived unit which is a standard measure of the dimension in which events occur in sequence. A dervied time unit is a derived unit which is a standard measure of the dimension in which events occur in sequence. A unit which is a standard measure of the dimension in which events occur in sequence. James Malone UO:0000149 http://www.ebi.ac.uk/efo/EFO_0001727 time derived unit time unit microeinstein per square meter per second Jon Ison http://www.ebi.ac.uk/efo/EFO_0004377 microeinstein per second and square meter mass percent A dimensionless concentration unit which denotes the mass of a substance in a mixture as a percentage of the mass of the entire mixture. mass percentage w/w weight-weight percentage volume percent % (v/v) A dimensionless concentration unit which denotes the volume of the solute in mL per 100 mL of the resulting solution. volume percentage part per million 10^[-6] A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1,000,000 regardless of the units of measure used as long as they are the same or 1 part in 10^[6]. ppm part per billion 10^[-9] A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1,000,000,000 regardless of the units of measure as long as they are the same or 1 part in 10^[9]. ppb gram per liter A gram per liter is a density unit which is equal to mass of an object in grams divided by the volume in liters. A mass unit density which is equal to mass of an object in grams divided by the volume in liters. James Malone Jon Ison UO:0000175 g/L http://www.ebi.ac.uk/efo/EFO_0001810 http://www.ebi.ac.uk/efo/EFO_0004372 milligram per milliliter A mass unit density which is equal to mass of an object in milligrams divided by the volume in milliliters. A milligram per milliliter is a density unit which is equal to mass of an object in milligrams divided by the volume in milliliters. James Malone UO:0000176 http://www.ebi.ac.uk/efo/EFO_0001809 mg/ml unit per milliliter Jon Ison U/ml http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Unit_per_Milliliter http://www.ebi.ac.uk/efo/EFO_0002932 density unit A density unit is a derived unit which is a standard measure of the influence exerted by some mass. A derived unit which is a standard measure of the influence exerted by some mass. A unit which is a standard measure of the influence exerted by some mass. James Malone UO:0000182 http://www.ebi.ac.uk/efo/EFO_0001808 dimensionless unit A derived unit which is a standard measure of physical quantity consisting of only a numerical number without any units. A unit which is a standard measure of physical quantity consisting of only a numerical number without any units. percent % A dimensionless ratio unit which denotes numbers as fractions of 100. degree fahrenheit A temperature derived unit which is equal to 5/9ths of a kelvin. Negative 40 degrees Fahrenheit is equal to negative 40 degrees Celsius. A temperature unit which is equal to 5/9ths of a kelvin. Negative 40 degrees Fahrenheit is equal to negative 40 degrees Celsius. F James Malone Jie Zheng MO_812 Tomasz Adamusiak degrees_F degrees_F[accessedResource: MO_812][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#degrees_F http://www.ebi.ac.uk/efo/EFO_0001701 milliliter per kilogram Jon Ison http://www.ebi.ac.uk/efo/EFO_0004380 ml/kg milliliter per liter A milliliter per liter is a unit of concentrationdefined as a volume per unit volume unit which is equal to one millionth of a liter of solute in one liter of solution. A volume per unit volume unit which is equal to one millionth of a liter of solute in one liter of solution. James Malone UO:0000207 http://www.ebi.ac.uk/efo/EFO_0001807 ml/l deciliter A deciliter is a volume unit which is equal to one tenth of a liter or 10^-1 L. A volume unit which is equal to one tenth of a liter or 10^[-1] L. James Malone Jie Zheng Jon Ison MO_624 Tomasz Adamusiak dl dl[accessedResource: MO_624][accessDate: 05-04-2011] http://mged.sourceforge.net/ontologies/MGEDOntology.owl#dl http://www.ebi.ac.uk/efo/EFO_0001716 dalton A dalton is a mass unit is an independent unit to the base SI units and is equal to one twelfth of the mass of an unbound atom of the carbon-12 nuclide, at rest and in its ground state. An independently to the base SI units defined mass unit which is equal to one twelfth of the mass of an unbound atom of the carbon-12 nuclide, at rest and in its ground state. Da James Malone UO:0000221 http://www.ebi.ac.uk/efo/EFO_0001710 u unified atomic mass unit milligram per liter http://www.ebi.ac.uk/efo/EFO_0004375 mg/L microgram per milliliter Jon Ison http://www.ebi.ac.uk/efo/EFO_0002905 ug/ml nanogram per milliliter James Malone http://www.ebi.ac.uk/efo/EFO_0002903 ng/ml rad An absorbed dose unit which is equal to 0.01 gray (Gy). george gkoutos fraction Definition: A dimensionless ratio unit which relates the part (the numerator) to the whole (the denominator). [Wikipedia] ciprofloxacin "Blue Bone" Formation 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid 1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid 1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid 22824 2824 85721-33-1 ABL1 ABL1 Gene ABL1 Gene[accessedResource: C17H18FN3O3][accessDate: 05-04-2011] ABL1[accessedResource: C17H18FN3O3][accessDate: 05-04-2011] C17H18FN3O3 C17H18FN3O3 InChI=1/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)/f/h23H InChIKey=MYSWGUAQZAJSOK-MPIMZMORCO OC(=O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O Quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. A second generation fluoroquinolone antibacterial, it works by interfering with the enzymes that cause DNA to rewind after being copied, so stopping DNA and protein synthesis. This gene is involved in cell adhesion, differentiation, division and stress response. This gene is involved in cell adhesion, differentiation, division and stress response.[accessedResource: C17H18FN3O3][accessDate: 05-04-2011] ciprofloxacine ciprofloxacino ciprofloxacinum ciproxin; cipro v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene[accessedResource: C17H18FN3O3][accessDate: 05-04-2011] 2-nitrofluorene 2-nitro-9H-fluorene 2-nitro-9H-fluorene 20971 607-57-8 971 A nitroarene that has formula C13H9NO2. A radiolabelled urea molecule used to diagnose stomach ulcers caused by Heliobacter pylori. In the presence of H. pylori, urea C-13 is metabolized by urease to produce ammonia and radioactive carbon dioxide at the interface between the gastric epithelium and lumen. The radioactive carbon dioxide is absorbed in the blood and is detected when exhaled in the breath. A radiolabelled urea molecule used to diagnose stomach ulcers caused by Heliobacter pylori. In the presence of H. pylori, urea C-13 is metabolized by urease to produce ammonia and radioactive carbon dioxide at the interface between the gastric epithelium and lumen. The radioactive carbon dioxide is absorbed in the blood and is detected when exhaled in the breath.[accessedResource: C13H9NO2][accessDate: 05-04-2011] C13 Urea C13 Urea[accessedResource: C13H9NO2][accessDate: 05-04-2011] C13H9NO2 C13H9NO2 Helicosol Helicosol[accessedResource: C13H9NO2][accessDate: 05-04-2011] InChI=1/C13H9NO2/c15-14(16)11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7H2 InChIKey=XFOHWECQTFIEIX-UHFFFAOYAJ NF Nitrofluorene O=N(=O)c1ccc-2c(Cc3ccccc-23)c1 UREA, C-13 UREA, C-13[accessedResource: C13H9NO2][accessDate: 05-04-2011] Urea C-13 Urea C-13[accessedResource: C13H9NO2][accessDate: 05-04-2011] 3,3',4,4'-tetrachlorobiphenyl 22514 3,3',4,4'-tetrachloro-1,1'-biphenyl 3,3',4,4'-tetrachlorobiphenyl 3,4,3',4'-Tetra coplanar polychlorinated biphenyl 32598-13-3 A synthetic form of the Ras peptide containing a point mutation at position 12 (glycine to cysteine) with potential antineoplastic activity. Vaccination with this peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for this Ras mutation, resulting in decreased tumor growth. (NCI04) A synthetic form of the Ras peptide containing a point mutation at position 12 (glycine to cysteine) with potential antineoplastic activity. Vaccination with this peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for this Ras mutation, resulting in decreased tumor growth. (NCI04)[accessedResource: C12H6Cl4][accessDate: 05-04-2011] A tetrachlorobiphenyl that has formula C12H6Cl4. C12H6Cl4 C12H6Cl4 Clc1ccc(cc1Cl)-c1ccc(Cl)c(Cl)c1 InChI=1/C12H6Cl4/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8/h1-6H InChIKey=UQMGJOKDKOLIDP-UHFFFAOYAU Ras (sub 5-17) Peptide (C12) Ras (sub 5-17) Peptide (C12)[accessedResource: C12H6Cl4][accessDate: 05-04-2011] Ras Peptide CYS Ras Peptide CYS[accessedResource: C12H6Cl4][accessDate: 05-04-2011] acetoacetate 141-81-1 20955 3-oxobutanoate 3-oxobutanoate 40955 Acetoacetate ion(1-) Butanoic acid, 3-oxo-, ion(1-) C4H5O3 C4H5O3 C4[accessedResource: C4H5O3][accessDate: 05-04-2011] CC(=O)CC([O-])=O Complement C4 Complement C4 Measurement Complement C4 Measurement[accessedResource: C4H5O3][accessDate: 05-04-2011] Complement C4[accessedResource: C4H5O3][accessDate: 05-04-2011] Complement Component-4 Complement component-4 (1744 aa, ~193 kDa) is part of the complement cascade, which mediates the innate immune response to infection. The full length protein is a precursor that can is secreted as a trimeric molecule containing an alpha, beta and gamma chain. When the complement cascade is initiated, the protein is cleaved. This proteolysis releases both the alpha chain, C4 anaphylatoxin, which stimulates inflammation, and a dimer of the beta and gamma chains, which mediates the interaction between the antigen-antibody complex and other complement components. InChI=1/C4H6O3/c1-3(5)2-4(6)7/h2H2,1H3,(H,6,7)/p-1/fC4H5O3/q-1 InChIKey=WDJHALXBUFZDSR-TZWAVNMPCM The determination of the amount of complement C4 present in a sample. The determination of the amount of complement C4 present in a sample.[accessedResource: C4H5O3][accessDate: 05-04-2011] selenate A selenium oxoanion that has formula O4Se. InChI=1/H2O4Se/c1-5(2,3)4/h(H2,1,2,3,4)/p-2/fO4Se/q-2 InChIKey=QYHFIVBSNOWOCQ-VMRORRRTCU O4Se SELENATE ION [O-][Se]([O-])(=O)=O [SeO4](2-) tetraoxidoselenate(2-) acetone 2-Propanone 67-64-1 A propanone that has formula C3H6O. Aceton Azeton C3H6O CC(C)=O Dimethyl ketone Dimethylketon InChI=1/C3H6O/c1-3(2)4/h1-2H3 InChIKey=CSCPPACGZOOCGX-UHFFFAOYAF Propanon dimethylcetone methyl ketone propan-2-one propanone acetylsalicylic acid 2-(acetyloxy)benzoic acid 2-Acetoxybenzenecarboxylic acid 2-acetoxybenzoic acid A benzoic acid derivative carrying an acetoxy group at the 2-position. ASA Acetylsalicylate Acetylsalicylsaeure Azetylsalizylsaeure Benzoic acid carrying an acetoxy group at the 2-position. C9H8O4 CC(=O)Oc1ccccc1C(O)=O CHEBI:15365 Easprin InChI=1/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)/f/h11H InChIKey=BSYNRYMUTXBXSQ-WXRBYKJCCW O-acetylsalicylic acid acide 2-(acetyloxy)benzoique acide acetylsalicylique acido acetilsalicilico acidum acetylsalicylicum aspirin http://www.ebi.ac.uk/efo/EFO_0001462 http://www.ebi.ac.uk/efo/EFO_0001463 o-acetoxybenzoic acid o-carboxyphenyl acetate salicylic acid acetate acetic acid 24394 4394 64-19-7 A simple carboxylic acid containing two carbons; the active ingredient in vinegar. The building block of natural fatty acids which, unlike them, does not occur in natural triglycerides. Reported to suppress accumulation of body fat and liver lipids in mice. C2 Mouse C2 Mouse[accessedResource: C2H4O2][accessDate: 05-04-2011] C2H4O2 C2H4O2 C2[accessedResource: C2H4O2][accessDate: 05-04-2011] CC(O)=O CH3-COOH Essigsaeure Ethanoic acid Ethylic acid HOAc InChI=1/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/f/h3H InChIKey=QTBSBXVTEAMEQO-TULZNQERCK Methanecarboxylic acid acetic acid acide acetique ethoic acid all-trans-retinoic acid (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL) A retinoic acid that has formula C20H28O2. AGN 100335 Acide retinoique (French) (DSL) C20H28O2 CC(\\C=C\\C1=C(C)CCCC1(C)C)=C/C=C/C(C)=C/C(O)=O CHEBI:15367 InChI=1/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+/f/h21H InChIKey=SHGAZHPCJJPHSC-FWNNKZREDV Renova Retin-A Retinoic acid Retisol-A Ro 1-5488 Stieva-A Tretin M Tretinoine (French) (EINECS) Vesanoid Vitamin A acid all-(E)-Retinoic acid all-trans-Tretinoin all-trans-Vitamin A acid all-trans-Vitamin A1 acid all-trans-beta-Retinoic acid beta-Retinoic acid http://www.ebi.ac.uk/efo/EFO_0001481 trans-Retinoic acid tretinoin endothelin-1 CHEBI:153671 Ele Holloway Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002728 acrolein 107-02-8 20023 23 Acrylaldehyde Acrylic aldehyde An enal that has formula C3H4O. C3 Gene C3 Gene[accessedResource: C3H4O][accessDate: 05-04-2011] C3H4O C3H4O C3[accessedResource: C3H4O][accessDate: 05-04-2011] Complement Component 3 Gene Complement Component 3 Gene[accessedResource: C3H4O][accessDate: 05-04-2011] InChI=1/C3H4O/c1-2-3-4/h2-3H,1H2 InChIKey=HGINCPLSRVDWNT-UHFFFAOYAQ Propenal This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade. This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade.[accessedResource: C3H4O][accessDate: 05-04-2011] [H]C(=C)C([H])=O acrylaldehyde 5,6,7,8-tetrahydrobiopterin 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one A biopterin that has formula C9H15N5O3. BH4 C9H15N5O3 CC(O)C(O)C1CNc2nc(N)[nH]c(=O)c2N1 CHEBI:15372 Ele Holloway InChI=1/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)/f/h11,14H,10H2 InChIKey=FNKQXYHWGSIFBK-JFOIYUNLCJ James Malone Tetrahydrobiopterin http://www.ebi.ac.uk/efo/EFO_0002397 water An inorganic hydroxy compound that has formula H2O. BOUND WATER H2O HOH InChI=1/H2O/h1H2 InChIKey=XLYOFNOQVPJJNP-UHFFFAOYAF James Malone Jie Zheng MO_380 Tomasz Adamusiak Wasser [H]O[H] [OH2] acqua agua aqua dihydridooxygen dihydrogen oxide eau http://mged.sourceforge.net/ontologies/MGEDOntology.owl#water http://www.ebi.ac.uk/efo/EFO_0001637 hydrogen hydroxide oxidane oxygen A homoatomic molecule that has formula O2. An elemental molecule that has formula O2. CHEBI:15379 Disauerstoff InChI=1/O2/c1-2 InChIKey=MYMOFIZGZYHOMD-UHFFFAOYAM O(2) O2 O=O OXYGEN MOLECULE dioxygen dioxygene http://www.ebi.ac.uk/efo/EFO_0002675 molecular oxygen (15Z)-12-oxophyto-10,15-dienoic acid (15Z)-12-Oxophyto-10,15-dienoate 12-OPDA 12-Oxo-10,15(Z)-phytodienoic acid 12-oxophytodienoic acid 23705 4-oxo-5-(2-pentenyl)-2-Cyclopentene-1-octanoic acid 43705 67204-66-4 8-(2-(cis-2'-Pentenyl)-3-oxo-cis-4-cyclopentenyl)octanoic acid 8-{(1S,5S)-4-oxo-5-[(2Z)-pent-2-en-1-yl]cyclopent-2-en-1-yl}octanoic acid 8-{(1S,5S)-4-oxo-5-[(2Z)-pent-2-en-1-yl]cyclopent-2-en-1-yl}octanoic acid 9(S),13(S)-12-Oxo-PDA An omega-3 fatty acid that has formula C18H28O3. C18H28O3 C18H28O3 CC\\C=C/C[C@H]1[C@@H](CCCCCCCC(O)=O)C=CC1=O EFABP EFABP[accessedResource: C18H28O3][accessDate: 05-04-2011] Epidermal Fatty Acid-Binding Protein Epidermal Fatty Acid-Binding Protein[accessedResource: C18H28O3][accessDate: 05-04-2011] Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI) Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI)[accessedResource: C18H28O3][accessDate: 05-04-2011] FABP5 FABP5[accessedResource: C18H28O3][accessDate: 05-04-2011] Fatty Acid Binding Protein 5 Fatty Acid Binding Protein 5[accessedResource: C18H28O3][accessDate: 05-04-2011] InChI=1/C18H28O3/c1-2-3-7-11-16-15(13-14-17(16)19)10-8-5-4-6-9-12-18(20)21/h3,7,13-16H,2,4-6,8-12H2,1H3,(H,20,21)/b7-3-/t15-,16-/m0/s1/f/h20H InChIKey=PMTMAFAPLCGXGK-OFJIPWNVDL OPDA PAFABP PAFABP[accessedResource: C18H28O3][accessDate: 05-04-2011] staurosporine (5S,6R,7R,9R)-6-methoxy-5-methyl-7-methylamino-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one An indolocarbazole alkaloid that has formula C28H26N4O3. An organic heterooctacyclic compound that has formula C28H26N4O3. C28H26N4O3 CHEBI:15738 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 InChI=1/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1/f/h30H InChIKey=HKSZLNNOFSGOKW-PULLEYNNDJ James Malone Staurosporin http://www.ebi.ac.uk/efo/EFO_0001613 Hexadecanoic acid 1-Pentadecanecarboxylic acid A straight-chain saturated fatty acid that has formula C16H32O2. A straight-chain, 16-carbon saturated fatty acid and major component of the oil from palm trees; the first fatty acid produced during lipogenesis, from which longer fatty acids can be produced. Reportedly has detrimental cardiovascular effects when there is insufficient intake of linoleic acid. A straight-chain, sixteen-carbon saturated fatty acid and major component of the oil from palm trees; the first fatty acid produced during lipogenesis, from which longer fatty acids can be produced. Reportedly has detrimental cardiovascular effects when there is insufficient intake of linoleic acid. A straight-chain, sixteen-carbon, saturated long-chain fatty acid. C16H32O2 CCCCCCCCCCCCCCCC(O)=O CH3-[CH2]14-COO(-) CH3-[CH2]14-COOH CHEBI:15756 Hexadecylic acid InChI=1/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)/f/h17H InChIKey=IPCSVZSSVZVIGE-HCKMINDGCQ Palmitic acid Palmitinsaeure Pentadecanecarboxylic acid cetylic acid hexadecanoate hexadecanoic acid, ion(1-) hexadecoic acid http://www.ebi.ac.uk/efo/EFO_0001552 n-hexadecanoic acid n-hexadecoic acid palmitate arachidonic acid (5Z,8Z,11Z,14Z)-Icosatetraenoic acid (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid A 20-carbon, polyunsaturated omega-6 fatty acid and one of the essential fatty acids required by most mammals; the counterpart to the saturated arachidic acid found in peanut oil. It is present in cell membrane phospholipids and abundant in brain and muscle. Its involvement in cellular signaling (as a lipid second messenger) is complemented by its key role as an inflammatory intermediate. It is also a precursor in the production of eicosanoids. AA ARA An icosa-5,8,11,14-tetraenoic acid that has formula C20H32O2. Arachidonsaeure C20H32O2 CCCCC\\C=C/C\\C=C/C\\C=C/C\\C=C/CCCC(O)=O CHEBI:15843 InChI=1/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-/f/h21H InChIKey=YZXBAPSDXZZRGB-FSPJQBAYDG all-cis-5,8,11,14-eicosatetraenoic acid cis-5,8,11,14-Eicosatetraenoic acid cis-Delta(5,8,11,14)-eicosatetraenoic acid http://www.ebi.ac.uk/efo/EFO_0001489 2-deoxy-D-glucose 154-17-6 17648 2-Deoxy-D-mannose 2-deoxy-D-arabino-hexopyranose 37648 A deoxy glucose having a hydroxy group replaced by a hydrogen at position 2; an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent. A deoxyglucose that has formula C6H12O5. C6H12O5 D-2dGlc D-arabino-2-Deoxyhexose Deoxyglucose InChI=1/C6H12O5/c7-2-1-4(9)6(11)5(10)3-8/h2,4-6,8-11H,1,3H2/t4-,5-,6+/m1/s1 InChIKey=VRYALKFFQXWPIH-PBXRRBTRBQ [H]C([H])(C=O)[C@@]([H])(O)[C@]([H])(O)[C@]([H])(O)CO phenol A member of the phenols that has formula C6H6O. A phenol that has formula C6H6O. Benzenol C6H6O CHEBI:15882 Carbolsaeure Ele Holloway Hydroxybenzene InChI=1/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H InChIKey=ISWSIDIOOBJBQZ-UHFFFAOYAI James Malone Karbolsaeure Oc1ccccc1 PhOH Phenic acid Phenylic acid acide carbolique acide phenique carbolic acid http://www.ebi.ac.uk/efo/EFO_0002417 methyl (-)-jasmonate 3-oxo-2-(2-pentenyl)cyclopentaneacetic acid methyl ester A jasmonate ester that has formula C13H20O3. C13H20O3 CC\\C=C/C[C@@H]1[C@H](CCC1=O)CC(=O)OC CHEBI:15929 Ele Holloway InChI=1/C13H20O3/c1-3-4-5-6-11-10(7-8-12(11)14)9-13(15)16-2/h4-5,10-11H,3,6-9H2,1-2H3/b5-4-/t10-,11-/m1/s1 InChIKey=GEWDNTWNSAZUDX-WQMVXFAEBM James Malone http://www.ebi.ac.uk/efo/EFO_0002413 methyl {(1R,2R)-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl}acetate atrazine 1912-24-9 2-CHLORO-4-ISOPROPYLAMINO-6-ETHYLAMINO-1,3,5-TRIAZINE 2-chloro-4-ethylamino-6-isopropylamino-s-triazine 20112 6-chloro-N-ethyl-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine 6-chloro-N-ethyl-N'-(propan-2-yl)-1,3,5-triazine-2,4-diamine 6-chloro-N-ethyl-N'-isopropyl-1,3,5-triazine-2,4-diamine 6-chloro-N-ethyl-N'-isopropyl-1,3,5-triazine-2,4-diamine A chloro-1,3,5-triazine herbicide that has formula C8H14ClN5. C8H14ClN5 C8H14ClN5 CCNc1nc(Cl)nc(NC(C)C)n1 CP25 CP25[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Encoded by HOXC6 Gene (ANTP Family), 153- and 235-amino acid (27-kD) Homeobox C6 Protein isoforms are highly conserved sequence-specific DNA-binding homeobox transcription repressors that can cooperate with other HOX proteins and may contribute to the breast cell phenotype through co-operative interactions. As part of a developmental regulatory system that provides anterior-posterior positional identity to cells, HOXC6 may regulate the coordinated expression of multiple genes involved in morphogenesis and differentiation. (from LocusLink, Swiss-Prot, OMIM, and NCI) HHO.C8 HHO.C8[accessedResource: C8H14ClN5][accessDate: 05-04-2011] HOX3C HOX3C[accessedResource: C8H14ClN5][accessDate: 05-04-2011] HOXC6 HOXC6[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Homeobox Protein 3C Homeobox Protein 3C[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Homeobox Protein C6 Homeobox Protein C6[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Homeobox Protein C8 Homeobox Protein C8[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Homeobox Protein CP25 Homeobox Protein CP25[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Homeobox Protein HHO.C8 Homeobox Protein HHO.C8[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Homeobox Protein HOXC6 Homeobox Protein HOXC6[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Homeobox Protein Hox-3C Homeobox Protein Hox-3C[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Homeobox Protein Hox-C6 Homeobox Protein Hox-C6[accessedResource: C8H14ClN5][accessDate: 05-04-2011] Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development. Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development.[accessedResource: C8H14ClN5][accessDate: 05-04-2011] InChI=1/C8H14ClN5/c1-4-10-7-12-6(9)13-8(14-7)11-5(2)3/h5H,4H2,1-3H3,(H2,10,11,12,13,14)/f/h10-11H InChIKey=MXWJVTOOROXGIU-PZWAIHAUCQ cholesterol (3beta)-cholest-5-en-3-ol 22401 2401 57-88-5 7 Alpha-Hydroxy-4-Cholesten-3-One 12-Alpha-Hydroxylase 7 Alpha-Hydroxy-4-Cholesten-3-One 12-Alpha-Hydroxylase[accessedResource: C27H46O][accessDate: 05-04-2011] A cholestanoid that has formula C27H46O. C27H46O C27H46O CYP8B1 CYP8B1[accessedResource: C27H46O][accessDate: 05-04-2011] CYPVIIIB1 CYPVIIIB1[accessedResource: C27H46O][accessDate: 05-04-2011] Cholest-5-en-3-ol (3beta)- Cholest-5-en-3-ol (3beta)-[accessedResource: MSH:D002784][accessDate: 05-04-2011] Cholest-5-en-3beta-ol Cholesterin Cytochrome P450 8B1 Cytochrome P450 8B1[accessedResource: C27H46O][accessDate: 05-04-2011] Cytochrome P450 CYP8B1 Cytochrome P450 CYP8B1[accessedResource: C27H46O][accessDate: 05-04-2011] Cytochrome P450 Family 8 Subfamily B Polypeptide 1 Cytochrome P450 Family 8 Subfamily B Polypeptide 1[accessedResource: C27H46O][accessDate: 05-04-2011] Cytochrome P450 Subfamily VIIIB (Sterol 12-Alpha-Hydroxylase) Polypeptide 1 Cytochrome P450 Subfamily VIIIB (Sterol 12-Alpha-Hydroxylase) Polypeptide 1[accessedResource: C27H46O][accessDate: 05-04-2011] Encoded by human CYP8B1 Gene (Cytochrome P450 Family), 501-aa 58-kDa Cytochrome P450 8B1 is a liver endoplasmic reticulum membrane P450 heme-thiolate monooxygenase involved in bile acid synthesis that catalyzes conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these steroids determines the relative amount of cholic and chenodeoxycholic acids secreted in the bile that affect cholesterol solubility. CYP8B1 has broad substrate specificity including 7-alpha-hydroxylated C27 steroids. P450 enzymes catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. (NCI) Encoded by human CYP8B1 Gene (Cytochrome P450 Family), 501-aa 58-kDa Cytochrome P450 8B1 is a liver endoplasmic reticulum membrane P450 heme-thiolate monooxygenase involved in bile acid synthesis that catalyzes conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these steroids determines the relative amount of cholic and chenodeoxycholic acids secreted in the bile that affect cholesterol solubility. CYP8B1 has broad substrate specificity including 7-alpha-hydroxylated C27 steroids. P450 enzymes catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. (NCI)[accessedResource: C27H46O][accessDate: 05-04-2011] Epicholesterol Epicholesterol[accessedResource: MSH:D002784][accessDate: 05-04-2011] InChI=1/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1 InChIKey=HVYWMOMLDIMFJA-DPAQBDIFBB MSH:D002784 Steroid 12-Alpha-Hydroxylase Steroid 12-Alpha-Hydroxylase[accessedResource: C27H46O][accessDate: 05-04-2011] Sterol 12 Alpha Hydroxylase Sterol 12 Alpha Hydroxylase[accessedResource: C27H46O][accessDate: 05-04-2011] The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.[accessedResource: MSH:D002784][accessDate: 05-04-2011] Tomasz Adamusiak [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C true ethanol 1-hydroxyethane A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. (PubChem) Pharmacology: Alcohol produces injury to cells by dehydration and precipitation of the cytoplasm or protoplasm. This accounts for its bacteriocidal and antifungal action. When alcohol is injected in close proximity to nerve tissues, it produces neuritis and nerve degeneration (neurolysis). Ninety to 98% of ethanol that enters the body is completely oxidized. Ethanol is also used as a cosolvent to dissolve many insoluble drugs and to serve as a mild sedative in some medicinal formulations. Mechanism of action: The sedative effects of ethanol are mediated through binding to GABA receptors and glycine receptors (alpha 1 and alpha 2 subunits). In its role as an anti-infective, ethanol acts as an osmolyte or dehydrating agent that disrupts the osmotic balance across cell membranes. Drug type: Approved. Small Molecule. Drug category: Anti-Infective Agents, Local. Central Nervous System Depressants. Disinfectants. Solvents A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. (PubChem) Pharmacology: Alcohol produces injury to cells by dehydration and precipitation of the cytoplasm or protoplasm. This accounts for its bacteriocidal and antifungal action. When alcohol is injected in close proximity to nerve tissues, it produces neuritis and nerve degeneration (neurolysis). Ninety to 98% of ethanol that enters the body is completely oxidized. Ethanol is also used as a cosolvent to dissolve many insoluble drugs and to serve as a mild sedative in some medicinal formulations. Mechanism of action: The sedative effects of ethanol are mediated through binding to GABA receptors and glycine receptors (alpha 1 and alpha 2 subunits). In its role as an anti-infective, ethanol acts as an osmolyte or dehydrating agent that disrupts the osmotic balance across cell membranes. Drug type: Approved. Small Molecule. Drug category: Anti-Infective Agents, Local. Central Nervous System Depressants. Disinfectants. Solvents[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] A member of the ethanols that has formula C2H6O. Absolute Alcohol Absolute Alcohol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Absolute Ethanol Absolute Ethanol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Aethanol Aethanol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Aethylalkohol Aethylalkohol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Alcare Hand Degermer Alcare Hand Degermer[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Alcohol Alcohol Anhydrous Alcohol Anhydrous[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Alcohol, Dehydrated Alcohol, Dehydrated[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Alcohol, Diluted Alcohol, Diluted[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Alcohol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Alcool Ethylique[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Alcool Etilico Alcool Etilico[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Algrain Algrain[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Alkohol Alkohol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Aminoethanol Aminoethanol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] An ethanol that has formula C2H6O. Anhydrol Anhydrol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Beta-Aminoethanol Beta-Aminoethanol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Beta-Aminoethyl Alcohol Beta-Aminoethyl Alcohol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Beta-Ethanolamine Beta-Ethanolamine[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Beta-Hydroxyethylamine Beta-Hydroxyethylamine[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] C2H5OH C2H6O CCO Caswell No, 426 Caswell No, 426[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Colamine Colamine[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Dehydrated Ethanol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Dehydrated ethanol Denatured Alcohol Denatured Alcohol Cd-10 Denatured Alcohol Cd-10[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Cd-5 Denatured Alcohol Cd-5[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Cd-5a Denatured Alcohol Cd-5a[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Sd-1 Denatured Alcohol Sd-13a Denatured Alcohol Sd-13a[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Sd-17 Denatured Alcohol Sd-17[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Sd-1[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Sd-23a Denatured Alcohol Sd-23a[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Sd-28 Denatured Alcohol Sd-28[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Sd-39b Denatured Alcohol Sd-39b[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Sd-39c Denatured Alcohol Sd-39c[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol Sd-3a Denatured Alcohol Sd-3a[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Alcohol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Denatured Ethanol Denatured Ethanol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] ETA ETA[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Envision Conditioner Pdd 9020 Envision Conditioner Pdd 9020[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] EtOH EtOH[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Etanolo Etanolo[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethanol 200 Proof Ethanol 200 Proof[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethanol Absolute Ethanol Absolute Bp Ethanol Absolute Bp[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethanol Absolute[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethanol Anhydrous Ethanol Anhydrous[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethanol Extra Pure Ethanol Extra Pure[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethanol, Silent Spirit Ethanol, Silent Spirit[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethanol, Spirit Ethanol, Spirit[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol Ethyl Alcohol & Water, 10% Ethyl Alcohol & Water, 10%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol & Water, 20% Ethyl Alcohol & Water, 20%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol & Water, 30% Ethyl Alcohol & Water, 30%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol & Water, 40% Ethyl Alcohol & Water, 40%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol & Water, 5% Ethyl Alcohol & Water, 5%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol & Water, 50% Ethyl Alcohol & Water, 50%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol & Water, 70% Ethyl Alcohol & Water, 70%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol & Water, 80% Ethyl Alcohol & Water, 80%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol & Water, 95% Ethyl Alcohol & Water, 95%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol & Water, 96% Ethyl Alcohol & Water, 96%[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol Anhydrous Ethyl Alcohol Anhydrous[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol, Anhydrous Ethyl Alcohol, Anhydrous[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol, Denatured Ethyl Alcohol, Denatured[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Alcohol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Hydrate Ethyl Hydrate[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethyl Hydroxide Ethyl Hydroxide[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethylol Ethylol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Ethylolamine Ethylolamine[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Glycinol Glycinol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] HSDB 531 HSDB 531[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] InChI=1/C2H6O/c1-2-3/h3H,2H2,1H3 InChIKey=LFQSCWFLJHTTHZ-UHFFFAOYAB James Malone Jaysol Jaysol S Jaysol S[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Jaysol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Methylcarbinol Methylcarbinol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] NIFSTD:nlx_chem_20090205 Pyro Pyro[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Reagent Alcohol Reagent Alcohol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Synasol Synasol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Tecsol Tecsol C Tecsol C[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Tecsol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Thanol Thanol[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Thiofaco M-50 Thiofaco M-50[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] Tomasz Adamusiak USAF EK-1597 USAF EK-1597[accessedResource: NIFSTD:nlx_chem_20090205][accessDate: 05-04-2011] [CH2Me(OH)] [OEtH] alcohol etilico alcool ethylique etanol http://www.ebi.ac.uk/efo/EFO_0001531 hydroxyethane spiritus vini hydrogen peroxide An inorganic peroxide that has formula H2O2. CHEBI:16240 H(2)O(2) H2O2 HOOH InChI=1/H2O2/c1-2/h1-2H InChIKey=MHAJPDPJQMAIIY-UHFFFAOYAL Oxydol [H]OO[H] [OH(OH)] bis(hydridooxygen)(O--O) dihydrogen dioxide dihydrogen peroxide dihydrogen(peroxide) dioxidane http://www.ebi.ac.uk/efo/EFO_0001553 quercetin 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one 3,5,7,3',4'-Pentahydroxyflavone A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. A pentahydroxyflavone that has formula C15H10O7. C15H10O7 CHEBI:16243 InChI=1/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H InChIKey=REFJWTPEDVJJIY-UHFFFAOYAW Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O http://www.ebi.ac.uk/efo/EFO_0001600 17beta-hydroxy-5alpha-androstan-3-one 17beta-hydroxyandrostan-3-one 5alpha-Dihydrotestosterone An androgen that has formula C19H30O2. Androstanolone C19H30O2 CHEBI:16330 DIHYDROTESTOSTERONE Dihydrotestosteron InChI=1/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1 InChIKey=NVKAWKQGWWIWPM-ABEVXSGRBZ James Malone Stanolone [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CCC(=O)C2 androstanolona androstanolonum dihydrotestoterone http://www.ebi.ac.uk/efo/EFO_0002007 hyaluronan (C14H21NO12)n 40500 9004-61-9 Hyaluronsaeure [beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n [beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n acide hyaluronique acido hialuronico hyaluronate hyaluronic acid 3-nitropropionic acid 20982 3-NPA 3-nitropropanoic acid 3-nitropropanoic acid 504-88-1 982 Bovinocidin C3 Gene C3 Gene[accessedResource: C3H5NO4][accessDate: 05-04-2011] C3H5NO4 C3H5NO4 C3[accessedResource: C3H5NO4][accessDate: 05-04-2011] Complement Component 3 Gene Complement Component 3 Gene[accessedResource: C3H5NO4][accessDate: 05-04-2011] InChI=1/C3H5NO4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)/f/h5H InChIKey=WBLZUCOIBUDNBV-JSWHHWTPCG OC(=O)CCN(=O)=O The 3-nitro derivative of propanoic acid. This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade. This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade.[accessedResource: C3H5NO4][accessDate: 05-04-2011] beta-Nitropropanoate beta-Nitropropanoic acid beta-Nitropropionic acid cholic acid (3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxycholan-24-oic acid (3alpha,5beta,7alpha,8alpha,12alpha,14beta,17alpha)-3,7,12-trihydroxycholan-24-oic acid 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanic acid 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid 81-25-4 A steroidal bile acid derived from cholesterol. C24H40O5 Cholsaeure InChI=1/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1/f/h28H InChIKey=BHQCQFFYRZLCQQ-NQEZNTFZDD [H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]1([H])C[C@H](O)[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])[C@H](O)C2)[C@H](C)CCC(O)=O cis-aconitate(3-) (1Z)-prop-1-ene-1,2,3-tricarboxylate An aconitate(3-) that has formula C6H3O6. C6H3O6 InChI=1/C6H6O6/c7-4(8)1-3(6(11)12)2-5(9)10/h1H,2H2,(H,7,8)(H,9,10)(H,11,12)/p-3/b3-1-/fC6H3O6/q-3 InChIKey=GTZCVFVGUGFEME-JWZZRJPODW [O-]C(=O)C\\C(=C\\C([O-])=O)C([O-])=O cis-aconitate indole-3-acetic acid (indol-3-yl)acetic acid 1H-indol-3-ylacetic acid 2-(indol-3-yl)ethanoic acid 3-Indolylessigsaeure A member of the indole-3-acetic acids that has formula C10H9NO2. An indole-3-acetic acid that has formula C10H9NO2. C10H9NO2 CHEBI:16411 IAA IES InChI=1/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)/f/h12H InChIKey=SEOVTRFCIGRIMH-XWKXFZRBCL Indoleacetic acid James Malone OC(=O)Cc1c[nH]c2ccccc12 heteroauxin http://www.ebi.ac.uk/efo/EFO_0001556 lipopolysaccharide CHEBI:16412 LPS Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). http://www.ebi.ac.uk/efo/EFO_0001564 lipopolysaccharides alanine 2-Aminopropionic acid 2-aminopropanoic acid 302-72-7 Alanin An alpha-amino acid that has formula C3H7NO2. C3H7NO2 CC(N)C(O)=O InChI=1/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/f/h5H InChIKey=QNAYBMKLOCPYGJ-JSWHHWTPCH alanina 17beta-estradiol (17beta)-estra-1,3,5(10)-triene-3,17-diol 17beta oestradiol An estradiol that has formula C18H24O2. C18H24O2 CHEBI:16469 Estradiol InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1 InChIKey=VOXZDWNPVJITMN-ZBRFXRBCBJ The 17beta-isomer of estradiol. [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21 beta-Estradiol cis-estradiol estra-1,3,5(10)-triene-3,17beta-diol http://www.ebi.ac.uk/efo/EFO_0001468 trans-zeatin (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol (E)-2-methyl-4-(1H-purin-6-ylamino)-2-buten-1-ol (E)-2-methyl-4-(1H-purin-6-ylamino)but-2-en-1-ol (E)-2-methyl-4-(purin-6-ylamino)-2-buten-1-ol (E)-zeatin 1637-39-4 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethylethanaminium 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethylethanaminium[accessedResource: C10H13N5O][accessDate: 05-04-2011] 20631 40631 A zeatin that has formula C10H13N5O. Aclatonium Aclatonium[accessedResource: C10H13N5O][accessDate: 05-04-2011] Aconitum ferox Root C10H13N5O C10H13N5O C\\C(CO)=C/CNc1ncnc2[nH]cnc12 Choline Lactate, Acetate Choline Lactate, Acetate[accessedResource: C10H13N5O][accessDate: 05-04-2011] Ethanaminium, 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethyl- Ethanaminium, 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethyl-[accessedResource: C10H13N5O][accessDate: 05-04-2011] InChI=1/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+/f/h11,13H InChIKey=UZKQTCBAMSWPJD-IQJMLFGSDN N6-(4-Hydroxyisopentenyl)adenine Zeatin D-serine (2R)-2-amino-3-hydroxypropanoic acid (R)-2-Amino-3-hydroxy-propionic acid (R)-2-amino-3-hydroxypropanoic acid A serine that has formula C3H7NO3. C3H7NO3 CHEBI:16523 D-Serin Ele Holloway InChI=1/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1/f/h6H InChIKey=MTCFGRXMJLQNBG-QKGSACKDDH N[C@H](CO)C(O)=O The R-enantiomer of serine. Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002727 carbon dioxide 124-38-9 27028 7028 A carbon oxide that has formula CO2. CO(2) CO2 InChI=1/CO2/c2-1-3 InChIKey=CURLTUGMZLYLDI-UHFFFAOYAO O=C=O [CO2] carbonic anhydride dioxidocarbon dioxomethane 20-hydroxyecdysone (22R)-2beta,3beta,14alpha,20,22,25-hexahydroxy-5beta-cholest-7-en-6-one (2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one 20-OH ecdysone 20388 40388 5289-74-7 7 Alpha-Hydroxy-4-Cholesten-3-One 12-Alpha-Hydroxylase 7 Alpha-Hydroxy-4-Cholesten-3-One 12-Alpha-Hydroxylase[accessedResource: C27H44O7][accessDate: 05-04-2011] A 20-hydroxy steroid that has formula C27H44O7. C27H44O7 C27H44O7 CYP8B1 CYP8B1[accessedResource: C27H44O7][accessDate: 05-04-2011] CYPVIIIB1 CYPVIIIB1[accessedResource: C27H44O7][accessDate: 05-04-2011] Cytochrome P450 8B1 Cytochrome P450 8B1[accessedResource: C27H44O7][accessDate: 05-04-2011] Cytochrome P450 CYP8B1 Cytochrome P450 CYP8B1[accessedResource: C27H44O7][accessDate: 05-04-2011] Cytochrome P450 Family 8 Subfamily B Polypeptide 1 Cytochrome P450 Family 8 Subfamily B Polypeptide 1[accessedResource: C27H44O7][accessDate: 05-04-2011] Cytochrome P450 Subfamily VIIIB (Sterol 12-Alpha-Hydroxylase) Polypeptide 1 Cytochrome P450 Subfamily VIIIB (Sterol 12-Alpha-Hydroxylase) Polypeptide 1[accessedResource: C27H44O7][accessDate: 05-04-2011] Encoded by human CYP8B1 Gene (Cytochrome P450 Family), 501-aa 58-kDa Cytochrome P450 8B1 is a liver endoplasmic reticulum membrane P450 heme-thiolate monooxygenase involved in bile acid synthesis that catalyzes conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these steroids determines the relative amount of cholic and chenodeoxycholic acids secreted in the bile that affect cholesterol solubility. CYP8B1 has broad substrate specificity including 7-alpha-hydroxylated C27 steroids. P450 enzymes catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. (NCI) Encoded by human CYP8B1 Gene (Cytochrome P450 Family), 501-aa 58-kDa Cytochrome P450 8B1 is a liver endoplasmic reticulum membrane P450 heme-thiolate monooxygenase involved in bile acid synthesis that catalyzes conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these steroids determines the relative amount of cholic and chenodeoxycholic acids secreted in the bile that affect cholesterol solubility. CYP8B1 has broad substrate specificity including 7-alpha-hydroxylated C27 steroids. P450 enzymes catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. (NCI)[accessedResource: C27H44O7][accessDate: 05-04-2011] InChI=1/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1 InChIKey=NKDFYOWSKOHCCO-YPVLXUMRBN Steroid 12-Alpha-Hydroxylase Steroid 12-Alpha-Hydroxylase[accessedResource: C27H44O7][accessDate: 05-04-2011] Sterol 12 Alpha Hydroxylase Sterol 12 Alpha Hydroxylase[accessedResource: C27H44O7][accessDate: 05-04-2011] [H][C@]12CC[C@]3(C)[C@]([H])(CC[C@@]3(O)C1=CC(=O)[C@]1([H])C[C@@H](O)[C@@H](O)C[C@]21C)[C@@](C)(O)[C@H](O)CCC(C)(C)O ecdysterone; 20E trichloroethylene 1,1,2-trichloroethene 1,1,2-trichloroethene 1,1-dichloro-2-chloroethylene 1382 21382 79-01-6 A chloroethene that has formula C2HCl3. C2 Mouse C2 Mouse[accessedResource: C2HCl3][accessDate: 05-04-2011] C2HCl3 C2HCl3 C2[accessedResource: C2HCl3][accessDate: 05-04-2011] ClC=C(Cl)Cl InChI=1/C2HCl3/c3-1-2(4)5/h1H InChIKey=XSTXAVWGXDQKEL-UHFFFAOYAI Narcogen TCE Trichloraethen Trichloraethylen acetylene trichloride ethinyl trichloride ethylene trichloride trichloraethylenum pro narcosi trichlorethylene trichloroethene trichloroethylenum triciene ecdysone (22R)-2beta,3beta,14,22,25-pentahydroxy-5beta-cholest-7-en-6-one (22R)-2beta,3beta,14alpha,22,25-pentahydroxy-5beta-cholest-7-en-6-one 3604-87-3 An ecdysteroid that has formula C27H44O6. C27H44O6 InChI=1/C27H44O6/c1-15(20(28)8-9-24(2,3)32)16-7-11-27(33)18-12-21(29)19-13-22(30)23(31)14-25(19,4)17(18)6-10-26(16,27)5/h12,15-17,19-20,22-23,28,30-33H,6-11,13-14H2,1-5H3/t15-,16+,17-,19-,20+,22+,23-,25+,26+,27+/m0/s1 InChIKey=UPEZCKBFRMILAV-JMZLNJERBR [H][C@@]1(CC[C@@]2(O)C3=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)[C@H](O)CCC(C)(C)O benzene 135 39242 71-43-2 A six-carbon aromatic compound in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system. Benzen Benzine Benzol Bicarburet of hydrogen C6 Vertebra C6 Vertebra[accessedResource: C6H6][accessDate: 05-04-2011] C6H6 C6H6 Coal naphtha InChI=1/C6H6/c1-2-4-6-5-3-1/h1-6H InChIKey=UHOVQNZJYSORNB-UHFFFAOYAH Mineral naphtha Phene Pyrobenzol Pyrobenzole The sixth of the seven cervical vertebrae. The sixth of the seven cervical vertebrae.[accessedResource: C6H6][accessDate: 05-04-2011] [6]annulene benzene benzole c1ccccc1 cyclohexatriene phenyl hydride cinnamaldehyde (3E)-3-phenylprop-2-enal 104-55-2 3-phenylacrylaldehyde 3-phenylprop-2-enal A member of the cinnamaldehydes that has formula C9H8O. C9H8O InChI=1/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+ InChIKey=KJPRLNWUNMBNBZ-QPJJXVBHBH O=C\\C=C\\c1ccccc1 The E (trans) stereoisomer of cinnamaldehyde, the parent of the class of cinnamaldehydes. 2,4-dichlorophenol 120-83-2 2,4-dichlorophenol 20439 439 A dichlorophenol that has formula C6H4Cl2O. C6 Vertebra C6 Vertebra[accessedResource: C6H4Cl2O][accessDate: 05-04-2011] C6H4Cl2O C6H4Cl2O DCP InChI=1/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H InChIKey=HFZWRUODUSTPEG-UHFFFAOYAU Oc1ccc(Cl)cc1Cl The sixth of the seven cervical vertebrae. The sixth of the seven cervical vertebrae.[accessedResource: C6H4Cl2O][accessDate: 05-04-2011] orotic acid 2,6-dihydroxypyrimidine-4-carboxylic acid 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid 25814 5814 65-86-1 A pyrimidinemonocarboxylic acid that has formula C5H4N2O4. C5 Gene C5 Gene[accessedResource: C5H4N2O4][accessDate: 05-04-2011] C5H4N2O4 C5H4N2O4 C5[accessedResource: C5H4N2O4][accessDate: 05-04-2011] Complement Component 5 Gene Complement Component 5 Gene[accessedResource: C5H4N2O4][accessDate: 05-04-2011] Human C5 wild-type allele is located within 9q33-q34 and is approximately 98 kb in length. This allele, which encodes complement C5 protein, is involved in the complement system, inflammatory responses, and histamine release. Human C5 wild-type allele is located within 9q33-q34 and is approximately 98 kb in length. This allele, which encodes complement C5 protein, is involved in the complement system, inflammatory responses, and histamine release.[accessedResource: C5H4N2O4][accessDate: 05-04-2011] InChI=1/C5H4N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)/f/h6-7,9H InChIKey=PXQPEWDEAKTCGB-BZTMKREHCW OC(=O)c1cc(=O)[nH]c(=O)[nH]1 Orotsaeure Uracil-6-carboxylic acid scopolamine "Blue Bone" Formation (1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0(2,4)]non-7-yl (2S)-3-hydroxy-2-phenylpropanoate (1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl (2S)-3-hydroxy-2-phenylpropanoate (1S,3S,5R,6R,7S)-6,7-epoxytropan-3-yl (2S)-3-hydroxy-2-phenylpropanoate 23573 3573 51-34-3 6,7-Epoxytropine tropate 6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate A propanoate ester that has formula C17H21NO4. A tropane alkaloid that is the (S)-tropic acid ester of 6beta,7beta-epoxy-1alphaH,5alphaH-tropan-3alpha-ol. ABL1 ABL1 Gene ABL1 Gene[accessedResource: C17H21NO4][accessDate: 05-04-2011] ABL1[accessedResource: C17H21NO4][accessDate: 05-04-2011] C17H21NO4 C17H21NO4 CN1[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Hyoscine InChI=1/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3/t11-,12-,13-,14+,15-,16+/m1/s1 InChIKey=STECJAGHUSJQJN-FWXGHANABA This gene is involved in cell adhesion, differentiation, division and stress response. This gene is involved in cell adhesion, differentiation, division and stress response.[accessedResource: C17H21NO4][accessDate: 05-04-2011] alpha-(Hydroxymethyl)benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2.4))non-7-yl ester v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene[accessedResource: C17H21NO4][accessDate: 05-04-2011] methionine 2-Amino-4-(methylthio)butyric acid 2-amino-4-(methylsulfanyl)butanoic acid 2-amino-4-(methylthio)butanoic acid A sulfur-containing amino acid that has formula C5H11NO2S. C5H11NO2S CSCCC(N)C(O)=O Hmet InChI=1/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/f/h7H InChIKey=FFEARJCKVFRZRR-QDQILVOLCH Methionin alpha-amino-gamma-methylmercaptobutyric acid metionina formaldehyde An aldehyde that has formula CH2O. CH2O CHEBI:16842 FORMALIN Formaldehyd InChI=1/CH2O/c1-2/h1H2 InChIKey=WSFSSNUMVMOOMR-UHFFFAOYAT Methanal Methylene oxide Oxomethane Oxomethylene The simplest aldehyde. [H]C([H])=O http://www.ebi.ac.uk/efo/EFO_0001538 glutathione 5-L-Glutamyl-L-cysteinylglycine A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine. C10H17N3O6S GSH GSH Glutathione is a tripeptide. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. It is an antioxidant that protects cells from toxins such as free radicals. GSH Glutathione is a tripeptide. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. It is an antioxidant that protects cells from toxins such as free radicals.[accessedResource: NIFSTD:nlx_mol_20090201][accessDate: 05-04-2011] InChI=1/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1/f/h12-13,15,18H InChIKey=RWSXRVCMGQZWBV-VSCBVDDUDG L-gamma-glutamyl-L-cysteinylglycine N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine NIFSTD:nlx_mol_20090201 N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O Reduced glutathione Tomasz Adamusiak gamma-L-Glutamyl-L-cysteinyl-glycine http://www.ebi.ac.uk/efo/EFO_0001547 D-mannitol (2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol A mannitol that has formula C6H14O6. C6H14O6 CHEBI:16899 InChI=1/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1 InChIKey=FBPFZTCFMRRESA-KVTDHHQDBH James Malone OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO Osmitrol The D-enantiomer of mannitol. http://www.ebi.ac.uk/efo/EFO_0001525 mannitol salicylic acid 2-carboxyphenol 2-hydroxybenzoic acid A hydroxybenzoic acid that has formula C7H6O3. C7H6O3 CHEBI:16914 InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)/f/h9H InChIKey=YGSDEFSMJLZEOE-BGGKNDAXCM James Malone OC(=O)c1ccccc1O http://www.ebi.ac.uk/efo/EFO_0001608 o-carboxyphenol o-hydroxybenzoic acid ortho-Hydroxylated benzoic acid. creatine (N-methylcarbamimidamido)acetic acid (alpha-methylguanido)acetic acid A derivative of glycine having methyl and amidino groups attached to the nitrogen. A glycine derivative that has formula C4H9N3O2. C4H9N3O2 CHEBI:16919 CN(CC(O)=O)C(N)=N Creatin InChI=1/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)/f/h5,8H,6H2 InChIKey=CVSVTCORWBXHQV-FVNFBLHMCI Kreatin Methylglycocyamine N-(aminoiminomethyl)-N-methylglycine N-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINE N-[amino(imino)methyl]-N-methylglycine N-amidinosarcosine N-methyl-N-guanylglycine alpha-Methylguanidino acetic acid http://www.ebi.ac.uk/efo/EFO_0001514 benzene-1,2,4-triol 20930 40930 533-73-3 C6 Vertebra C6 Vertebra[accessedResource: C6H6O3][accessDate: 05-04-2011] C6H6O3 The sixth of the seven cervical vertebrae. The sixth of the seven cervical vertebrae.[accessedResource: C6H6O3][accessDate: 05-04-2011] benzene-1,2,4-triol beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl glycopeptide DNA (Deoxyribonucleotide)m (Deoxyribonucleotide)n (Deoxyribonucleotide)n+m A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine) (MSH). A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine) (MSH).[accessedResource: NIFSTD:sao454034570][accessDate: 05-04-2011] DNA is a chemical compound which has a high molecular weight, linear polymers and is composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contains the genetic information of organisms. DNAn DNAn+1 DNS Deoxyribonucleic acid[accessedResource: NIFSTD:sao454034570][accessDate: 05-04-2011] Desoxyribonukleinsaeure High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms. James Malone Jie Zheng MO_945 NIFSTD:sao454034570 Tomasz Adamusiak deoxyribonucleic acid deoxyribonucleic acids desoxyribose nucleic acid http://mged.sourceforge.net/ontologies/MGEDOntology.owl#DNA http://www.ebi.ac.uk/efo/EFO_0001453 thymus nucleic acid cholesterol ester C28H45O2R Cholesterol esterified at the 3-hydroxy group. [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC([*])=O)[C@H](C)CCCC(C)C cholesterol esters progesterone (S)-4-Pregnene-3,20-dione (S)-Pregn-4-en-3,20-dione (S)-Progesterone 17alpha-progesterone 4-Pregnene-3,20-dione A 3-oxo Delta(4)-steroid that has formula C21H30O2. A steroid hormone that has formula C21H30O2. Agolutin Akrolutin C21H30O2 CHEBI:17026 Crinone Delta(4)-pregnene-3,20-dione Gelbkoerperhormon InChI=1/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1 InChIKey=RJKFOVLPORLFTN-LEKSSAKUBC Progesteron [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])C(C)=O corpus luteum hormone http://www.ebi.ac.uk/efo/EFO_0001598 luteohormone pregn-4-ene-3,20-dione chitin (1->4)-2-acetamido-2-deoxy-beta-D-glucan (C8H13NO5)n A N-acylglucosamine that has formula (C8H13NO5)n. An aminoglycan that has formula (C8H13NO5)n. CHEBI:17029 InChI=1/C24H41N3O16/c1-7(31)25-13-18(36)20(11(5-29)39-22(13)38)42-24-15(27-9(3)33)19(37)21(12(6-30)41-24)43-23-14(26-8(2)32)17(35)16(34)10(4-28)40-23/h10-24,28-30,34-38H,4-6H2,1-3H3,(H,25,31)(H,26,32)(H,27,33)/t10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+,24+/m1/s1/f/h25-27H InChIKey=WZZVUHWLNMNWLW-IRGKDUGGDK [1,4-(N-Acetyl-beta-D-glucosaminyl)]n [4)-beta-D-GlcpNAc(1->]n beta-1,4-Poly-N-acetyl-D-glucosamine http://www.ebi.ac.uk/efo/EFO_0001502 methyl glyoxal 1,2-propanedione 1628 2-Ketopropionaldehyde 2-oxopropanal 2-oxopropanal 2-oxopropionaldehyde 21628 78-98-8 A 2-oxo aldehyde that has formula C3H4O2. A 2-oxoaldehyde derived from propanal. C3 Gene C3 Gene[accessedResource: C3H4O2][accessDate: 05-04-2011] C3H4O2 C3H4O2 C3[accessedResource: C3H4O2][accessDate: 05-04-2011] CH3COCHO Complement Component 3 Gene Complement Component 3 Gene[accessedResource: C3H4O2][accessDate: 05-04-2011] InChI=1/C3H4O2/c1-3(5)2-4/h2H,1H3 InChIKey=AIJULSRZWUXGPQ-UHFFFAOYAZ Pyruvaldehyde Pyruvic aldehyde This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade. This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade.[accessedResource: C3H4O2][accessDate: 05-04-2011] [H]C(=O)C(C)=O acetylformaldehyde acetylformyl alpha-ketopropionaldehyde methylglyoxal 17alpha-estradiol An estradiol that has formula C18H24O2. C18H24O2 CHEBI:17160 InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1 InChIKey=VOXZDWNPVJITMN-SFFUCWETBJ [H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21 alpha-estradiol estra-1,3,5(10)-triene-3,17alpha-diol estra-1,3,5(10)trien-3,17alpha-diol http://www.ebi.ac.uk/efo/EFO_0001467 myrcene 123-35-3 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethylethanaminium 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethylethanaminium[accessedResource: C10H16][accessDate: 05-04-2011] 25692 5692 7-methyl-3-methylene-1,6-octadiene 7-methyl-3-methyleneocta-1,6-diene 7-methyl-3-methyleneocta-1,6-diene 7-methyl-3-methylideneocta-1,6-diene A monoterpene that has formula C10H16. Aclatonium Aclatonium[accessedResource: C10H16][accessDate: 05-04-2011] Aconitum ferox Root C10H16 C10H16 CC(C)=CCCC(=C)C=C Choline Lactate, Acetate Choline Lactate, Acetate[accessedResource: C10H16][accessDate: 05-04-2011] Ethanaminium, 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethyl- Ethanaminium, 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethyl-[accessedResource: C10H16][accessDate: 05-04-2011] InChI=1/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3 InChIKey=UAHWPYUMFXYFJY-UHFFFAOYAT beta-myrcene glucose C6H12O6 CHEBI:17234 Glc Glukose MSH:D005947 gluco-hexose http://www.ebi.ac.uk/efo/EFO_0001545 true mono-2-ethylhexyl phthalate (2-ethylhexyl) hydrogen phthalate 1,2-benzenedicarboxylic acid, mono(2-ethylhexyl) ester 2-(2-ethylhexyloxycarbonyl)benzoic acid 2-([(2-ethylhexyl)oxy]carbonyl)benzoic acid 2-Ethylhexyl phthalate A phthalate ester that has formula C16H22O4. C16H22O4 CCCCC(CC)COC(=O)c1ccccc1C(O)=O CHEBI:17243 InChI=1/C16H22O4/c1-3-5-8-12(4-2)11-20-16(19)14-10-7-6-9-13(14)15(17)18/h6-7,9-10,12H,3-5,8,11H2,1-2H3,(H,17,18)/f/h17H InChIKey=DJDSLBVSSOQSLW-HCKMINDGCL MEHP The mono(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid. http://www.ebi.ac.uk/efo/EFO_0001574 mono(2-ethylhexyl) phthalate monoethylhexyl phthalate phthalic acid, 2-ethylhexyl ester carbon monoxide A carbon oxide that has formula CO. CHEBI:17245 InChI=1/CO/c1-2 InChIKey=UGFAIRIUMAVXCW-UHFFFAOYAT James Malone [CO] carbon monooxide carbon(II) oxide http://www.ebi.ac.uk/efo/EFO_0001500 morphine (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol (5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol A highly potent opiate analgesic psychoactive drug, morphine acts directly on the central nervous system (CNS) to relieve pain. Morphine has a high potential for addiction; tolerance and both physical and psychological dependence develop rapidly. A morphinane alkaloid that has formula C17H19NO3. C17H19NO3 CHEBI:17303 Ele Holloway InChI=1/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 InChIKey=BQJCRHHNABKAKU-KBQPJGBKBH James Malone Morphia Morphin [H][C@]12C=C[C@H](O)[C@@H]3Oc4c(O)ccc5C[C@H]1N(C)CC[C@@]23c45 http://www.ebi.ac.uk/efo/EFO_0002414 morfina morphinum morphium testosterone (8alpha,10alpha,13alpha,14beta,17alpha)-17-hydroxyandrost-4-en-3-one 17 beta Hydroxy 4 Androsten 3 one 17 beta Hydroxy 4 Androsten 3 one[accessedResource: MSH:D013739][accessDate: 05-04-2011] 17 beta Hydroxy 8 alpha 4 Androsten 3 one 17 beta Hydroxy 8 alpha 4 Androsten 3 one[accessedResource: MSH:D013739][accessDate: 05-04-2011] 17-beta-Hydroxy-4-Androsten-3-one 17-beta-Hydroxy-4-Androsten-3-one[accessedResource: MSH:D013739][accessDate: 05-04-2011] 17-beta-Hydroxy-8 alpha-4-Androsten-3-one 17-beta-Hydroxy-8 alpha-4-Androsten-3-one[accessedResource: MSH:D013739][accessDate: 05-04-2011] 17beta-hydroxy-4-androsten-3-one 17beta-hydroxyandrost-4-en-3-one 4-androsten-17beta-ol-3-one 8 Isotestosterone 8 Isotestosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] 8-Isotestosterone 8-Isotestosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL. A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.[accessedResource: MSH:D013739][accessDate: 05-04-2011] An androgen that has formula C19H28O2. An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5. AndroGel AndroGel[accessedResource: MSH:D013739][accessDate: 05-04-2011] Androderm Androderm[accessedResource: MSH:D013739][accessDate: 05-04-2011] Andropatch Andropatch[accessedResource: MSH:D013739][accessDate: 05-04-2011] Androst-4-en-17beta-ol-3-one Androst-4-en-17beta-ol-3-one[accessedResource: MSH:D013739][accessDate: 05-04-2011] Androtop Androtop[accessedResource: MSH:D013739][accessDate: 05-04-2011] AstraZeneca Brand of Testosterone AstraZeneca Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Auxilium Pharmaceuticals Inc. Brand of Testosterone Auxilium Pharmaceuticals Inc. Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Bartor Brand of Testosterone Bartor Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] C19H28O2 CEPA Brand of Testosterone CEPA Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] CHEBI:17347 Dr. Kade Brand of Testosterone Dr. Kade Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Faulding Brand of Testosterone Faulding Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Ferring Brand of Testosterone Ferring Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] GlaxoSmithKline Brand of Testosterone GlaxoSmithKline Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Hauck Brand of Testosterone Hauck Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Histerone Histerone[accessedResource: MSH:D013739][accessDate: 05-04-2011] InChI=1/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1 InChIKey=MUMGGOZAMZWBJJ-DYKIIFRCBC James Malone MSH:D013739 Ortho Brand of Testosterone Ortho Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Paladin Brand of Testosterone Paladin Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Pasadena Brand of Testosterone Pasadena Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Schering Brand of Testosterone Schering Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] SmithKline Beecham Brand of Testosterone SmithKline Beecham Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Solvay Brand of Testosterone Solvay Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Sterotate Sterotate[accessedResource: MSH:D013739][accessDate: 05-04-2011] Sustanon Sustanon[accessedResource: MSH:D013739][accessDate: 05-04-2011] Testim Testim[accessedResource: MSH:D013739][accessDate: 05-04-2011] Testoderm Testoderm[accessedResource: MSH:D013739][accessDate: 05-04-2011] Testolin Testolin[accessedResource: MSH:D013739][accessDate: 05-04-2011] Testopel Testopel[accessedResource: MSH:D013739][accessDate: 05-04-2011] Testosteron Testosterone Sulfate Testosterone Sulfate[accessedResource: MSH:D013739][accessDate: 05-04-2011] Tomasz Adamusiak Ulmer Brand of Testosterone Ulmer Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Unimed Brand of Testosterone Unimed Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] Unlike testosterone, which is a flat molecule, its 8-isomer has a folded conformation. Unlike testosterone, which is a flat molecule, its 8-isomer has a folded conformation.[accessedResource: MSH:D013739][accessDate: 05-04-2011] Watson Brand of Testosterone Watson Brand of Testosterone[accessedResource: MSH:D013739][accessDate: 05-04-2011] [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H] http://www.ebi.ac.uk/efo/EFO_0001676 testosterona testosteronum quinoline 10-Deacetyltaxol 1798 21798 91-22-5 A series of reactions that result in formation of a pore, composed of complement proteins C5b, C6, C7, C8, and C9, in the membrane of a pathogenic cell. The pore allows free diffusion of molecules into and out of the cell and reduces cell viability. A series of reactions that result in formation of a pore, composed of complement proteins C5b, C6, C7, C8, and C9, in the membrane of a pathogenic cell. The pore allows free diffusion of molecules into and out of the cell and reduces cell viability.[accessedResource: C9H7N][accessDate: 05-04-2011] Activation of Membrane Attack Complex Activation of Membrane Attack Complex[accessedResource: C9H7N][accessDate: 05-04-2011] An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis. C9H7N C9H7N Chinolin InChI=1/C9H7N/c1-2-6-9-8(4-1)5-3-7-10-9/h1-7H InChIKey=SMWDFEZZVXVKRB-UHFFFAOYAU The simplest member of the quinoline class of compounds, comprising a benzene ring ortho fused to C-2 and C-3 of a pyridine ring. benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))- benzo[b]pyridine c1ccc2ncccc2c1 quinoline 3',5'-cyclic AMP (2R,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide 3',5'-cyclic purine nucleotide having having adenine as the nucleobase. A 3',5'-cyclic purine nucleotide that has formula C10H12N5O6P. ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE Adenosine 3',5'-phosphate C10H12N5O6P CHEBI:17489 Cyclic AMP Cyclic adenylic acid InChI=1/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1/f/h17H,11H2 InChIKey=IVOMOUWHDPKRLL-BJEHYBLCDS Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O adenosine 3',5'-(hydrogen phosphate) cAMP http://www.ebi.ac.uk/efo/EFO_0001471 cysteine (2R)-2-amino-3-mercaptopropanoic acid (2R)-2-amino-3-sulfanylpropanoic acid (R)-2-amino-3-mercaptopropanoic acid A cysteine that has formula C3H7NO2S. An optically active form of cysteine having L-configuration. C C3H7NO2S CHEBI:17561 Cys FREE CYSTEINE InChI=1/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1/f/h5H InChIKey=XUJNEKJLAYXESH-SNQCPAJUDK L-2-Amino-3-mercaptopropionic acid L-Cystein L-Zystein L-cysteine N[C@@H](CS)C(O)=O http://www.ebi.ac.uk/efo/EFO_0001516 nitrate 14797-55-8 24217 4217 A nitrogen oxoanion that has formula NO3. InChI=1/NO3/c2-1(3)4/q-1 InChIKey=NHNBFGGVMKEFGY-UHFFFAOYAI NITRATE ION NO3 [NO3](-) [O-]N(=O)=O nitrate nitrate(1-) trioxidonitrate(1-) trioxonitrate(1-) trioxonitrate(V) cortisol (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione 11beta,17,21-trihydroxypregn-4-ene-3,20-dione 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione 11beta-hydrocortisone 17-hydroxycorticosterone 4-pregnen-11beta,17alpha,21-triol-3,20-dione 50-23-7 C21H30O5 Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses Hydrocortisone InChI=1/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 InChIKey=JYGXADMDTFJGBT-VWUMJDOOBO Kendall's compound F Reichstein's substance M [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO hidrocortisona hydrocortisonum chloramphenicol 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide A dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and an alcohol function. A dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions. C11H12Cl2N2O5 CHEBI:17698 Chloramex Chlorocid Chlorocol Chloromycetin D-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenylethyl)acetamide D-(-)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol Ele Holloway Fenicol Globenicol Halomycetin InChI=1/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1/f/h14H InChIKey=WIIZWVCIJKGZOK-TUYINDPHDP James Malone OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)N(=O)=O Oleomycetin Sificetina chloramphenicolum cloramfenicol http://www.ebi.ac.uk/efo/EFO_0002403 laevomycetinum levomicetina levomycetin diethylhexyl phthalate 1,2-Benzenedicarboxylic acid bis(2-ethylhexyl) ester 2-Ethylhexyl phthalate A phthalate ester that has formula C24H38O4. Bis(2-ethylhexyl) o-phthalate Bis(2-ethylhexyl)phthalate Bis(ethylhexyl) phthalate C24H38O4 CCCCC(CC)COC(=O)c1ccccc1C(=O)OCC(CC)CCCC CHEBI:17747 DEHP Di(2-ethylhexyl) o-phthalate Di(2-ethylhexyl)orthophthalate Di(2-ethylhexyl)phthalate Di-sec-octyl phthalate Dioctyl phthalate InChI=1/C24H38O4/c1-5-9-13-19(7-3)17-27-23(25)21-15-11-12-16-22(21)24(26)28-18-20(8-4)14-10-6-2/h11-12,15-16,19-20H,5-10,13-14,17-18H2,1-4H3 InChIKey=BJQHLKABXJIVAM-UHFFFAOYAB Octyl phthalate Phthalic acid bis(2-ethylhexyl) ester Phthalic acid di(2-ethylhexyl) ester The bis(2-ethylhexyl) ester of 1,2-benzenedicarboxylic acid. The bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid. bis(2-ethylhexyl) 1,2-benzenedicarboxylate bis(2-ethylhexyl) benzene-1,2-dicarboxylate bis(2-ethylhexyl) phthalate di-iso-Octyl phthalate http://www.ebi.ac.uk/efo/EFO_0001521 methanol CH3OH CH4O CHEBI:17790 CO InChI=1/CH4O/c1-2/h2H,1H3 InChIKey=OKKJLVBELUTLKV-UHFFFAOYAX James Malone MeOH Methyl alcohol Methylalkohol The simplest aliphatic alcohol, comprising a methyl and an alcohol group. carbinol http://www.ebi.ac.uk/efo/EFO_0001672 wood alcohol wood naphtha wood spirit calcitriol (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol (1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol 1,25-DHCC 1alpha,25(OH)2D3 1alpha,25-dihydroxycholecalciferol 1alpha,25-dihydroxyvitamin D3 1alpha,25-dihydroxyvitamin D3; 1,25-dihydroxyvitamin D3; 1,25(OH)2D3 22722 32222-06-3 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL 7 Alpha-Hydroxy-4-Cholesten-3-One 12-Alpha-Hydroxylase 7 Alpha-Hydroxy-4-Cholesten-3-One 12-Alpha-Hydroxylase[accessedResource: C27H44O3][accessDate: 05-04-2011] A hydroxycalciol that has formula C27H44O3. C27H44O3 C27H44O3 CYP8B1 CYP8B1[accessedResource: C27H44O3][accessDate: 05-04-2011] CYPVIIIB1 CYPVIIIB1[accessedResource: C27H44O3][accessDate: 05-04-2011] Calcijex Cytochrome P450 8B1 Cytochrome P450 8B1[accessedResource: C27H44O3][accessDate: 05-04-2011] Cytochrome P450 CYP8B1 Cytochrome P450 CYP8B1[accessedResource: C27H44O3][accessDate: 05-04-2011] Cytochrome P450 Family 8 Subfamily B Polypeptide 1 Cytochrome P450 Family 8 Subfamily B Polypeptide 1[accessedResource: C27H44O3][accessDate: 05-04-2011] Cytochrome P450 Subfamily VIIIB (Sterol 12-Alpha-Hydroxylase) Polypeptide 1 Cytochrome P450 Subfamily VIIIB (Sterol 12-Alpha-Hydroxylase) Polypeptide 1[accessedResource: C27H44O3][accessDate: 05-04-2011] Decostriol Encoded by human CYP8B1 Gene (Cytochrome P450 Family), 501-aa 58-kDa Cytochrome P450 8B1 is a liver endoplasmic reticulum membrane P450 heme-thiolate monooxygenase involved in bile acid synthesis that catalyzes conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these steroids determines the relative amount of cholic and chenodeoxycholic acids secreted in the bile that affect cholesterol solubility. CYP8B1 has broad substrate specificity including 7-alpha-hydroxylated C27 steroids. P450 enzymes catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. (NCI) Encoded by human CYP8B1 Gene (Cytochrome P450 Family), 501-aa 58-kDa Cytochrome P450 8B1 is a liver endoplasmic reticulum membrane P450 heme-thiolate monooxygenase involved in bile acid synthesis that catalyzes conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these steroids determines the relative amount of cholic and chenodeoxycholic acids secreted in the bile that affect cholesterol solubility. CYP8B1 has broad substrate specificity including 7-alpha-hydroxylated C27 steroids. P450 enzymes catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. (NCI)[accessedResource: C27H44O3][accessDate: 05-04-2011] InChI=1/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1 InChIKey=GMRQFYUYWCNGIN-NKMMMXOEBI Rocaltrol Steroid 12-Alpha-Hydroxylase Steroid 12-Alpha-Hydroxylase[accessedResource: C27H44O3][accessDate: 05-04-2011] Sterol 12 Alpha Hydroxylase Sterol 12 Alpha Hydroxylase[accessedResource: C27H44O3][accessDate: 05-04-2011] [H][C@@]1(CC[C@@]2([H])\\C(CCC[C@]12C)=C\\C=C1\\C[C@@H](O)C[C@H](O)C1=C)[C@H](C)CCCC(C)(C)O calcitriolum gentamicin (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl (6x)-2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-alpha-D-erythro-heptopyranoside 1403-66-3 3091 34642 4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp. C21 C21H43N5O7 C21[accessedResource: C21H43N5O7][accessDate: 05-04-2011] DC42 DC42[accessedResource: C21H43N5O7][accessDate: 05-04-2011] FLJ12894 FLJ12894[accessedResource: C21H43N5O7][accessDate: 05-04-2011] Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia. Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia.[accessedResource: C21H43N5O7][accessDate: 05-04-2011] IRA1 IRA1[accessedResource: C21H43N5O7][accessDate: 05-04-2011] TBL1XR1 wt Allele TBL1XR1 wt Allele[accessedResource: C21H43N5O7][accessDate: 05-04-2011] TBLR1 TBLR1[accessedResource: C21H43N5O7][accessDate: 05-04-2011] Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele[accessedResource: C21H43N5O7][accessDate: 05-04-2011] Transducin (Beta)-Like 1X-Linked Receptor 1 Gene Transducin (Beta)-Like 1X-Linked Receptor 1 Gene[accessedResource: C21H43N5O7][accessDate: 05-04-2011] gentamycin gentamycins hydrochloric acid 20711 711 7647-01-0 A diatomic molecule containing covalently bonded hydrogen and chlorine atoms. Chlorwasserstoff Cl[H] HCl Hydrogenchlorid InChI=1/ClH/h1H InChIKey=VEXZGXHMUGYJMC-UHFFFAOYAT Wasserstoffchlorid [HCl] chlorane chloridohydrogen chlorure d'hydrogene cloruro de hidrogeno hydrogen chloride hydrogen chloride alpha-D-glucose A D-glucopyranose that has formula C6H12O6. C6H12O6 CHEBI:17925 InChI=1/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1 InChIKey=WQZGKKKJIJFFOK-DVKNGEFBBQ OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O alpha-D-glucopyranose alpha-dextrose http://www.ebi.ac.uk/efo/EFO_0001482 asymmetric dimethylarginine (2S)-2-amino-5-(N',N'-dimethylcarbamimidamido)pentanoic acid (2S)-2-amino-5-{[(dimethylamino)(imino)methyl]amino}pentanoic acid 16758 36758 63937-30-4 A methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group. A methyl-L-arginine that has formula C8H18N4O2. ADMA C8H18N4O2 C8H18N4O2 CN(C)C(=N)NCCC[C@H](N)C(O)=O CP25 CP25[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Encoded by HOXC6 Gene (ANTP Family), 153- and 235-amino acid (27-kD) Homeobox C6 Protein isoforms are highly conserved sequence-specific DNA-binding homeobox transcription repressors that can cooperate with other HOX proteins and may contribute to the breast cell phenotype through co-operative interactions. As part of a developmental regulatory system that provides anterior-posterior positional identity to cells, HOXC6 may regulate the coordinated expression of multiple genes involved in morphogenesis and differentiation. (from LocusLink, Swiss-Prot, OMIM, and NCI) HHO.C8 HHO.C8[accessedResource: C8H18N4O2][accessDate: 05-04-2011] HOX3C HOX3C[accessedResource: C8H18N4O2][accessDate: 05-04-2011] HOXC6 HOXC6[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Homeobox Protein 3C Homeobox Protein 3C[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Homeobox Protein C6 Homeobox Protein C6[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Homeobox Protein C8 Homeobox Protein C8[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Homeobox Protein CP25 Homeobox Protein CP25[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Homeobox Protein HHO.C8 Homeobox Protein HHO.C8[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Homeobox Protein HOXC6 Homeobox Protein HOXC6[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Homeobox Protein Hox-3C Homeobox Protein Hox-3C[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Homeobox Protein Hox-C6 Homeobox Protein Hox-C6[accessedResource: C8H18N4O2][accessDate: 05-04-2011] Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development. Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development.[accessedResource: C8H18N4O2][accessDate: 05-04-2011] InChI=1/C8H18N4O2/c1-12(2)8(10)11-5-3-4-6(9)7(13)14/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14)/t6-/m0/s1/f/h10-11,13H InChIKey=YDGMGEXADBMOMJ-GNCCJFBBDQ N(5)-((dimethylamino)iminomethyl)-L-ornithine N(5)-(N,N-dimethylcarbamimidoyl)-L-ornithine N(5)-[(dimethylamino)(imino)methyl]-L-ornithine N(G),N(G)-dimethylarginine N(G)-dimethylarginine N(G1),N(G1)-dimethylarginine N(omega),N(omega)-dimethyl-L-arginine N,N-dimethylarginine N5-[(dimethylamino)(imino)methyl]-L-ornithine NG,NG-DIMETHYL-L-ARGININE guanidino-N,N-dimethylarginine puromycin (S)-3'-((2-Amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyladenosine 16788 3'-(L-alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine 3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-diemthyladenosine 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine 3'-deoxy-N,N-dimethyl-3'-[(O-methyl-L-tyrosyl)amino]adenosine 3'-deoxy-N,N-dimethyl-3'-[(O-methyl-L-tyrosyl)amino]adenosine 36788 53-79-2 9-{3-deoxy-3-[(O-methyl-L-tyrosyl)amino]-beta-D-xylofuranosyl}-N,N-dimethyl-9H-purin-6-amine A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration. A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration.[accessedResource: C22H29N7O5][accessDate: 05-04-2011] Achromycin An aminonucleoside antibiotic, derived from the Streptomyces alboniger bacterium, that causes premature chain termination during translation taking place in the ribosome. Brassidic Acid Brassidic Acid[accessedResource: C22H29N7O5][accessDate: 05-04-2011] C22:1, n-9 trans C22:1, n-9 trans[accessedResource: C22H29N7O5][accessDate: 05-04-2011] C22H29N7O5 C22H29N7O5 COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1 Fatty Acid 22:1 n-9 trans Fatty Acid 22:1 n-9 trans[accessedResource: C22H29N7O5][accessDate: 05-04-2011] Fatty Acid trans 22:1 n-9 Fatty Acid trans 22:1 n-9[accessedResource: C22H29N7O5][accessDate: 05-04-2011] InChI=1/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1/f/h27H InChIKey=RXWNCPJZOCPEPQ-RXOQHODBDL Trans docos-13-enoic Acid Trans docos-13-enoic Acid[accessedResource: C22H29N7O5][accessDate: 05-04-2011] puromicina puromycine puromycinum butyrate 1-butanoate 1-butyrate 1-propanecarboxylate A fatty acid anion that has formula C4H7O2. A straight-chain saturated fatty acid anion that has formula C4H7O2. C4H7O2 CCCC([O-])=O CH3-[CH2]2-COO(-) CHEBI:17968 InChI=1/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)/p-1/fC4H7O2/q-1 InChIKey=FERIUCNNQQJTOY-PAXZUDBGCU The conjugate base of butyric acid. butanate butanoate butanoic acid, ion(1-) ethylacetate http://www.ebi.ac.uk/efo/EFO_0001496 n-butanoate n-butyrate propanecarboxylate propylformate sucrose 1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranoside A glycosyl glycoside that has formula C12H22O11. C12H22O11 CHEBI:17992 Cane sugar InChI=1/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1 InChIKey=CZMRCDWAGMRECN-UGDNZRGBBE OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O Saccharose Sacharose beta-D-Fruf-(2<->1)-alpha-D-Glcp beta-D-fructofuranosyl alpha-D-glucopyranoside http://www.ebi.ac.uk/efo/EFO_0001616 sacarosa table sugar 1-aminocyclopropane-1-carboxylic acid 1-aminocyclopropanecarboxylic acid 1-aminocyclopropanecarboxylic acid 22059-21-8 39577 A alpha-amino acid consisting of cyclopropane having amino and carboxy substituents both at the 1-position. An alpha-amino acid that has formula C4H7NO2. C4H7NO2 C4H7NO2 C4[accessedResource: C4H7NO2][accessDate: 05-04-2011] Complement C4 Complement C4 Measurement Complement C4 Measurement[accessedResource: C4H7NO2][accessDate: 05-04-2011] Complement C4[accessedResource: C4H7NO2][accessDate: 05-04-2011] Complement Component-4 Complement component-4 (1744 aa, ~193 kDa) is part of the complement cascade, which mediates the innate immune response to infection. The full length protein is a precursor that can is secreted as a trimeric molecule containing an alpha, beta and gamma chain. When the complement cascade is initiated, the protein is cleaved. This proteolysis releases both the alpha chain, C4 anaphylatoxin, which stimulates inflammation, and a dimer of the beta and gamma chains, which mediates the interaction between the antigen-antibody complex and other complement components. InChI=1/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)/f/h6H InChIKey=PAJPWUMXBYXFCZ-BRMMOCHJCR NC1(CC1)C(O)=O The determination of the amount of complement C4 present in a sample. The determination of the amount of complement C4 present in a sample.[accessedResource: C4H7NO2][accessDate: 05-04-2011] oxamic acid A dicarboxylic acid amide that has formula C2H3NO3. C2H3NO3 CHEBI:18058 InChI=1/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)/f/h5H,3H2 InChIKey=SOWBFZRMHSNYGE-YPUDGCQOCP NC(=O)C(O)=O Oxalic monoamide Oxamate The monoamide of oxalic acid. amino(oxo)acetic acid http://www.ebi.ac.uk/efo/EFO_0001588 (+)-alpha-tocopherol (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol (2R,4'R,8'R)-alpha-tocopherol (R,R,R)-alpha-tocopherol 5,7,8-trimethyltocol An alpha-tocopherol that has formula C29H50O2. C29H50O2 CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1 CHEBI:18145 InChI=1/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1 InChIKey=GVJHHUAWPYXKBD-IEOSBIPEBS James Malone MSH:D014810 Vitamin E d-alpha-tocopherol http://www.ebi.ac.uk/efo/EFO_0001465 true ethene Aethen Aethylen An alkene that has formula C2H4. C2H4 C=C CH2=CH2 CHEBI:18153 H2C=CH2 InChI=1/C2H4/c1-2/h1-2H2 InChIKey=VGGSQFUCUMXWEO-UHFFFAOYAE James Malone ethylene http://www.ebi.ac.uk/efo/EFO_0001532 gamma-tocopherol (2R)-2,7,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol (2R)-3,4-dihydro-2,7,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 7,8-dimethyltocol A tocopherol that has formula C28H48O2. C28H48O2 CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1 CHEBI:18185 D-gamma-tocopherol Ele Holloway InChI=1/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1 InChIKey=QUEDXNHFTDJVIY-DQCZWYHMBO Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002729 selenite(2-) 14124-67-5 A selenium oxoanion that has formula O3Se. InChI=1/H2O3Se/c1-4(2)3/h(H2,1,2,3)/p-2/fO3Se/q-2 InChIKey=MCAHWIHFGHIESP-YDERIHRJCL O3Se Selenit [O-][Se]([O-])=O [SeO3](2-) selenite trioxidoselenate(2-) trioxoselenate(2-) trioxoselenate(IV) isoflavone 3-Phenylchromone 3-phenyl-4H-1-benzopyran-4-one 3-phenyl-4H-chromen-4-one A member of the isoflavones that has formula C15H10O2. An isoflavone that has formula C15H10O2. C15H10O2 CHEBI:18220 InChI=1/C15H10O2/c16-15-12-8-4-5-9-14(12)17-10-13(15)11-6-2-1-3-7-11/h1-10H InChIKey=GOMNOOKGLZYEJT-UHFFFAOYAO Isoflavon O=c1c(coc2ccccc12)-c1ccccc1 http://www.ebi.ac.uk/efo/EFO_0001558 xylose An aldopentose, found in the embryos of most edible plants and used in medicine to test for malabsorption by administration in water to the patient. C5H10O5 CHEBI:18222 InChI=1/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5+/m0/s1 InChIKey=PYMYPHUHKUWMLA-VPENINKCBR OC[C@@H](O)[C@H](O)[C@@H](O)C=O Xyl http://www.ebi.ac.uk/efo/EFO_0002681 xylo-pentose dopamine 2-(3,4-dihydroxyphenyl)ethylamine 3,4-Dihydroxyphenethylamine 3-Hydroxytyramine 4-(2-aminoethyl)-1,2-benzenediol 4-(2-aminoethyl)benzene-1,2-diol 4-(2-aminoethyl)catechol 4-(2-aminoethyl)pyrocatechol A catecholamine that has formula C8H11NO2. C8H11NO2 Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group. Deoxyepinephrine Dopamin Dopamine HCl Dophamine Hydroxytyramin Hydroxytyramine InChI=1/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 InChIKey=VYFYYTLLBUKUHU-UHFFFAOYAA Intropin James Malone NCCc1ccc(O)c(O)c1 NIFSTD:sao2050279787 One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrin. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action (MSH). One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action. (PubChem) Pharmacology: Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal tract, and in a few peripheral sympathetic nerves. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings. Mechanism of action: Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings. Drug type: Approved. Small Molecule. Drug category: Cardiotonic Agents. Dopamine Agents. Sympathomimetic. Sympathomimetics Oxytyramine Revimine Tomasz Adamusiak dopamina dopaminum http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Molecule.owl#sao2050279787 http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Molecule.owl#sao2050279787[accessedResource: NIFSTD:sao2050279787][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0001526 iron 26Fe An iron group element atom that has formula Fe. An iron group element that has formula Fe. CHEBI:18248 Eisen Ele Holloway InChI=1/Fe InChIKey=XEEYBQQBJWHFJM-UHFFFAOYAG James Malone [Fe] fer ferrum hierro http://www.ebi.ac.uk/efo/EFO_0002410 iron atom true 3,3',5-triiodo-L-thyronine 3,5,3'TRIIODOTHYRONINE 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism. An iodothyronine that has formula C15H12I3NO4. C15H12I3NO4 CHEBI:18258 Ele Holloway InChI=1/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1/f/h21H InChIKey=AUYYCJSJGJYCDS-YROMPDBNDH James Malone L-3,5,3'-Triiodothyronine L-T3 N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine T3 Tertroxin Tresitope Triiodothyronine http://www.ebi.ac.uk/efo/EFO_0002395 liothyronine liothyroninum liotironina jasmonic acid (1R,2R)-3-oxo-2-(2Z)-2-penten-ylcyclopentanacetic acid (1R,2R)-3-oxo-2-(pent-2Z-enyl)-cyclopentaneacetic acid 2-{(1R,2R)-3-oxo-2-[(Z)-pent-2-enyl]cyclopentyl}acetate An oxo monocarboxylic acid that has formula C12H18O3. C12H18O3 CC\\C=C/C[C@@H]1[C@H](CCC1=O)CC(O)=O CHEBI:18292 InChI=1/C12H18O3/c1-2-3-4-5-10-9(8-12(14)15)6-7-11(10)13/h3-4,9-10H,2,5-8H2,1H3,(H,14,15)/b4-3-/t9-,10-/m1/s1/f/h14H InChIKey=ZNJFBWYDHIGLCU-JXYCJCKWDR Jasmonate http://www.ebi.ac.uk/efo/EFO_0001560 {(1R,2R)-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl}acetic acid 1,4-dithiothreitol (R*,R*)-1,4-dimercapto-2,3-butanediol 03/12/3483 C4H10O2S2 Cleland's reagent DL-threo-1,4-Dimercapto-2,3-butanediol DTT; dithiothreitol Dithiothreitol Dithiotreitol InChI=1/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2 InChIKey=VHJLVAABSRFDPM-UHFFFAOYAZ OC(CS)C(O)CS The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol. rac-Dithiothreitol rel-(2R,3R)-1,4-disulfanylbutane-2,3-diol threo-1,4-Dimercapto-2,3-butanediol sulphur dioxide A sulfur oxide that has formula O2S. CHEBI:18422 InChI=1/O2S/c1-3-2 InChIKey=RAHZWNYVWXNFOC-UHFFFAOYAT O2S O=S=O SO2 Schwefel(IV)-oxid Schwefeldioxid Sulfur dioxide dioxidosulfur http://www.ebi.ac.uk/efo/EFO_0001619 oxosulfane oxide sulfurous anhydride sulfurous oxide 5-fluorouridine 5-Fluorouracil 1beta-D-ribofuranoside C9H11FN2O6 Ele Holloway InChI=1/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1/f/h11H InChIKey=FHIDNBAQOFJWCA-OPTMDVTPDF James Malone OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(F)c(=O)[nH]c1=O The 5-fluoro derivative of uridine. Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002489 nicotine (RS)-nicotine 3-(1-methylpyrrolidin-2-yl)pyridine A pyrrolidine alkaloid that has formula C10H14N2. C10H14N2 CHEBI:18723 CN1CCCC1c1cccnc1 Ele Holloway InChI=1/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3 InChIKey=SNICXCGAKADSCV-UHFFFAOYAX James Malone Nicotin Nikotin http://www.ebi.ac.uk/efo/EFO_0002415 5-azacytidine 4-Amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one 4-amino-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one A N-glycosyl-1,3,5-triazine that has formula C8H12N4O5. Azacitidine C8H12N4O5 CHEBI:2038 InChI=1/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1/f/h9H2 InChIKey=NMUSYJAQQFHJEW-QUSQBIOGDY Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1 http://www.ebi.ac.uk/efo/EFO_0002667 abscisic acid (2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid Abscisinsaeure Abszisinsaeure An apo carotenoid sesquiterpenoid that has formula C15H20O4. C15H20O4 CC(\\C=C\\C1(O)C(C)=CC(=O)CC1(C)C)=C\\C(O)=O CHEBI:22152 InChI=1/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/f/h17H InChIKey=JLIDBLDQVAYHNE-RGWLVKBGDZ acide abscissique acido abscisico http://www.ebi.ac.uk/efo/EFO_0001477 alkylating agent CHEBI:22333 Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases. James Malone http://www.ebi.ac.uk/efo/EFO_0001816 alpha-tocopherol 10191-41-0 2,5,7,8-tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol C29H50O2 dl-alpha-tocopherol rel-(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol true vitamin E antibiotic Antibiotika Antibiotikum James Malone Substance produced by, and obtained from, certain living cells (especially bacteria, yeasts and moulds), or an equivalent synthetic substance, which is biostatic or biocidal at low concentrations to some other form of life, especially pathogenic or noxious organisms. antibiotics antibiotique http://www.ebi.ac.uk/efo/EFO_0001485 antimycin A (2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison. Antimycin A1 Antipiricullin C28H40N2O9 CHEBI:22584 Fintrol InChI=1/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1/f/h29-30H InChIKey=UIFFUZWRFRDZJC-MBZNLELHDN Virosin [H]C(=O)Nc1cccc(C(=O)N[C@H]2[C@@H](C)OC(=O)[C@H](CCCCCC)[C@@H](OC(=O)CC(C)C)[C@H](C)OC2=O)c1O antimycin A1b http://www.ebi.ac.uk/efo/EFO_0002668 antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. CHEBI:22586 James Malone antioxidants antioxydant antoxidant http://www.ebi.ac.uk/efo/EFO_0001817 auxin Any of a group of compounds, both naturally occurring and synthetic, that regulate aspects of plant growth (from Greek alphaupsilonxialphanuomega, "to grow"). CHEBI:22676 James Malone auxins http://www.ebi.ac.uk/efo/EFO_0001818 benzenetriols CHEBI:22707 James Malone benzenetriol http://www.ebi.ac.uk/efo/EFO_0001665 phytogenic insecticide An insecticide compound naturally occurring in plants. CHEBI:22917 James Malone botanical insecticide botanical insecticides http://www.ebi.ac.uk/efo/EFO_0001819 phytogenic insecticides cadmium 23940 3940 48Cd 7440-43-9 A zinc group element atom that has formula Cd. Cd InChI=1/Cd InChIKey=BDOSMKKIYDKNTQ-UHFFFAOYAU Kadmium [Cd] cadmio cadmium cadmium atom cadmium compounds CHEBI:22978 cadmium molecular entities cadmium molecular entity http://www.ebi.ac.uk/efo/EFO_0001497 calcium ionophore CHEBI:22986 Ele Holloway James Malone calcium ionophores http://www.ebi.ac.uk/efo/EFO_0002402 colchicine A carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. A carbotricyclic compound that has formula C22H25NO6. C22H25NO6 CHEBI:23359 COC1=CC=C2C(=CC1=O)C(CCc3cc(OC)c(OC)c(OC)c23)NC(C)=O InChI=1/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/f/h23H InChIKey=IAKHMKGGTNLKSZ-MPIMZMORCX N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide http://www.ebi.ac.uk/efo/EFO_0001512 compatible osmolytes CHEBI:23366 James Malone http://www.ebi.ac.uk/efo/EFO_0001820 AACOCF3 (6Z,9Z,12Z,15Z)-1,1,1-trifluorohenicosa-6,9,12,15-tetraen-2-one An organofluorine compound that has formula C21H31F3O. Arachidonic acid trifluoromethyl ketone Arachidonyl trifluoromethyl ketone Arachidonyltrifluoromethane C21H31F3O CCCCC\\C=C/C\\C=C/C\\C=C/C\\C=C/CCCC(=O)C(F)(F)F CHEBI:2341 InChI=1/C21H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(25)21(22,23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15- InChIKey=PLWROONZUDKYKG-DOFZRALJBM James Malone http://www.ebi.ac.uk/efo/EFO_0001476 copper(2+) sulfate A metal sulfate compound having copper(2+) as the counterion. CHEBI:23414 CuO4S CuSO4 Cupric sulfate InChI=1/Cu.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2/fCu.O4S/qm;-2 InChIKey=ARUVKPQLZAKDPS-NJTCMIMLCU [Cu++].[O-]S([O-])(=O)=O copper sulfate copper(II) sulfate cupric sulfate anhydrous http://www.ebi.ac.uk/efo/EFO_0001513 cytochalasin B CHEBI:23527 http://www.ebi.ac.uk/efo/EFO_0001517 cytokinins CHEBI:23530 James Malone http://www.ebi.ac.uk/efo/EFO_0001821 abacavir 136470-78-5 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(3,4,4-trimethylhepta-2,5-dien-1-yl)sulfanyl]ethyl}amino)propyl]amino}butyl]dihydrogen diphosphate} 3,4,4-trimethylhepta-2,5-dienyl-CoA C31H48N7O19P3S CC(=CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)C(C)(C)C=CC(O)=O Delta(2,5)-3,4,4-trimethylpimeloyl-CoA InChI=1/C31H48N7O19P3S/c1-17(30(2,3)8-6-20(40)41)12-21(42)61-11-10-33-19(39)7-9-34-28(45)25(44)31(4,5)14-54-60(51,52)57-59(49,50)53-13-18-24(56-58(46,47)48)23(43)29(55-18)38-16-37-22-26(32)35-15-36-27(22)38/h6,8,12,15-16,18,23-25,29,43-44H,7,9-11,13-14H2,1-5H3,(H,33,39)(H,34,45)(H,40,41)(H,49,50)(H,51,52)(H2,32,35,36)(H2,46,47,48)/t18-,23-,24-,25+,29-/m1/s1/f/h33-34,40,46-47,49,51H,32H2 InChIKey=DEQKKPDRDCEPQL-UACJGMJGDX delta2,5-3,4,4-trimethylpimelyl-CoA (+)-abscisic acid (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid (7E,9Z)-(6S)-6-hydroxy-3-oxo-11-apo-epsilon-caroten-11-oic acid (S)-(+)-abscisic acid 2-cis,4-trans-abscisic acid ABA An abscisic acid that has formula C15H20O4. C15H20O4 CC(\\C=C\\[C@@]1(O)C(C)=CC(=O)CC1(C)C)=C\\C(O)=O CHEBI:2365 InChI=1/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1/f/h17H InChIKey=JLIDBLDQVAYHNE-MPLKMVHTDC James Malone The naturally occurring (1'S)-(+) enantiomer of abscisic acid. It is an important sesquiterpenoid plant hormone which acts as a regulator of plant responses to environmental stresses such as drought and cold. abscisin II http://www.ebi.ac.uk/efo/EFO_0001464 drug Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. drugs http://www.ebi.ac.uk/efo/EFO_0002604 medicine enzyme inhibitor A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. CHEBI:23924 James Malone enzyme inhibitors http://www.ebi.ac.uk/efo/EFO_0001822 inhibidor enzimatico inhibidores enzimaticos inhibiteur enzymatique inhibiteurs enzymatiques ethyl nitrosourea 1-(Aminocarbonyl)-1-ethyl-2-oxohydrazine 1-ethyl-1-nitrosourea A urea compound having ethyl and nitroso substituents in the 1-position. Aethylnitroso-harnstoff C3H7N3O2 CCN(N=O)C(N)=O CHEBI:23995 ENU InChI=1/C3H7N3O2/c1-2-6(5-8)3(4)7/h2H2,1H3,(H2,4,7)/f/h4H2 InChIKey=FUSGACRLAFQQRL-LGEMBHMGCE N-Ethyl-N-nitroso carbamide N-Ethyl-N-nitroso-urea N-Ethylnitrosourea N-ethyl-N-nitrosourea NEU http://www.ebi.ac.uk/efo/EFO_0001533 fungicide A substance used to destroy fungal pests. CHEBI:24127 James Malone fungicides http://www.ebi.ac.uk/efo/EFO_0001823 acyclovir 2-amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one 59277-89-3 A 2-aminopurine that has formula C8H11N5O3. C8H11N5O3 InChI=1/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)/f/h12H,9H2 InChIKey=MKUXAQIIEYXACX-TVNKGWMHCG Nc1nc2n(COCCO)cnc2c(=O)[nH]1 Zovir aciclovir aciclovirum hormone An endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function. endocrine hormones http://www.ebi.ac.uk/efo/EFO_0002657 hypochlorous acid 16737 36737 7790-92-3 A weak, unstable acid with formula HOCl, which is the active form of chlorine in water. Chlor(I)-saeure ClHO HClO HClO HOCl InChI=1/ClHO/c1-2/h2H InChIKey=QWPPOHNGKGFGJK-UHFFFAOYAT OCl [ClOH] chloranol hydroxidochlorine hypochloric acid hypochlorige Saeure hypochlorous acid insecticide A substance used to destroy pests of the class Insecta. CHEBI:24852 James Malone http://www.ebi.ac.uk/efo/EFO_0001825 insecticides jasmonic acids CHEBI:24937 James Malone http://www.ebi.ac.uk/efo/EFO_0001826 jasmonates lead 82Pb A carbon group element atom that has formula Pb. A carbon group element that has formula Pb. Blei CHEBI:25016 Ele Holloway InChI=1/Pb InChIKey=WABPQHHGFIMREM-UHFFFAOYAT James Malone [Pb] http://www.ebi.ac.uk/efo/EFO_0002412 lead atom plomb plomo plumbum aflatoxin B1 "Blue Bone" Formation (6aR,9aS)-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione 1162-65-8 2,3,6aalpha,9aalpha-Tetrahydro-4-methoxycyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione 20035 35 4-(methyloxy)-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione ABL1 ABL1 Gene ABL1 Gene[accessedResource: C17H12O6][accessDate: 05-04-2011] ABL1[accessedResource: C17H12O6][accessDate: 05-04-2011] AFB1 An aflatoxin that has formula C17H12O6. C17H12O6 C17H12O6 InChI=1/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3/t8-,17+/m0/s1 InChIKey=OQIQSTLJSLGHID-WNWIJWBNBK This gene is involved in cell adhesion, differentiation, division and stress response. This gene is involved in cell adhesion, differentiation, division and stress response.[accessedResource: C17H12O6][accessDate: 05-04-2011] [H][C@]12OC=C[C@@]1([H])c1c(O2)cc(OC)c2c3CCC(=O)c3c(=O)oc12 v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene[accessedResource: C17H12O6][accessDate: 05-04-2011] linoleic acids Any of two trienoic essential fatty acids; a nutrient essential to the formation of prostaglandins. Also used in making paints and synthetic resins. CHEBI:25048 http://www.ebi.ac.uk/efo/EFO_0001563 linolenic acid linolenic acids agarose (1->4)-3,6-anhydro-alpha-L-galactopyranosyl-(1->3)-beta-D-galactopyranan (C12H18O9)n 9012-36-6 A polysaccharide that has formula (C12H18O9)n. InChI=1/C24H38O19/c25-1-5-9(27)11(29)12(30)22(38-5)41-17-8-4-36-20(17)15(33)24(40-8)43-18-10(28)6(2-26)39-23(14(18)32)42-16-7-3-35-19(16)13(31)21(34)37-7/h5-34H,1-4H2/t5-,6-,7+,8+,9+,10+,11+,12-,13+,14-,15+,16-,17-,18+,19+,20+,21-,22+,23+,24+/m1/s1 InChIKey=MJQHZNBUODTQTK-WKGBVCLCBX Sepharose [4)-3,6-An-alpha-L-Galp-(1->3)-beta-D-Galp-(1->]n methyl methanesulfonate A methanesulfonate ester that has formula C2H6O3S. C2H6O3S CB1540 CHEBI:25255 COS(C)(=O)=O InChI=1/C2H6O3S/c1-5-6(2,3)4/h1-2H3 InChIKey=MBABOKRGFJTBAE-UHFFFAOYAK MMS Methanesulfonic acid methyl ester Methyl mesylate as-Dimethyl sulfite http://www.ebi.ac.uk/efo/EFO_0001573 mitochondrial respiratory-chain inhibitor CHEBI:25355 James Malone http://www.ebi.ac.uk/efo/EFO_0001827 mitochondrial electron transport chain inhibitors mitochondrial electron-transport chain inhibitor mitochondrial respiratory chain inhibitors bis(2-chloroethyl) sulfide 1,1'-thiobis(2-chloroethane) 1-chloro-2-[(2-chloroethyl)sulfanyl]ethane 1-chloro-2-[(2-chloroethyl)thio]ethane An ethyl sulfide that has formula C4H8Cl2S. C4H8Cl2S CHEBI:25434 ClCCSCCCl InChI=1/C4H8Cl2S/c5-1-3-7-4-2-6/h1-4H2 InChIKey=QKSKPIVNLNLAAV-UHFFFAOYAK James Malone Lost Senfgas Yperite bis(2-chloroethyl) sulphide bis(2-chloroethyl)sulfane http://www.ebi.ac.uk/efo/EFO_0001492 mustard gas sulfur mustard mutagen An agent that increases the frequency of spontanenous mutation, usually by interacting directly with DNA and causing it damage, including base substitution. CHEBI:25435 James Malone http://www.ebi.ac.uk/efo/EFO_0001828 mutagene mutagenes mutagenic agent mutageno mutagenos mutagens 7,12-dimethylbenz(a)anthracene 1,4-Dimethyl-2,3-benzphenanthrene 11-Eicosenoic Acid 11-Eicosenoic Acid[accessedResource: C20H16][accessDate: 05-04-2011] 20510 510 57-97-6 6,7-Dimethyl-1,2-benzanthracene 7,12-DMBA 7,12-Dimethyl-1,2-benzanthracene 7,12-Dimethyl-1:2-benz(a)anthracene 7,12-Dimethylbenzanthracene 7,12-Dimethylbenzanthrancene 7,12-dimethylbenzo[a]anthracene 7,12-dimethyltetraphene 7,12-dimethyltetraphene 9,10-Dimethyl-1,2-benzanthracene 9,10-Dimethyl-1,2-benzanthrazen 9,10-Dimethylbenz(a)anthracene A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration. A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration.[accessedResource: C20H16][accessDate: 05-04-2011] A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke. C20:1 n-9 cis C20:1 n-9 cis[accessedResource: C20H16][accessDate: 05-04-2011] C20H16 C20H16 Cc1c2ccccc2c(C)c2c1ccc1ccccc21 Cis-icos-11-enoic Cis-icos-11-enoic[accessedResource: C20H16][accessDate: 05-04-2011] DMBA Fatty Acid 20:1 n-9 Fatty Acid 20:1 n-9[accessedResource: C20H16][accessDate: 05-04-2011] Gondoic Acid Gondoic Acid[accessedResource: C20H16][accessDate: 05-04-2011] InChI=1/C20H16/c1-13-16-8-5-6-9-17(16)14(2)20-18(13)12-11-15-7-3-4-10-19(15)20/h3-12H,1-2H3 InChIKey=ARSRBNBHOADGJU-UHFFFAOYAX myxothiazol (2E,4R,5S,6E)-3,5-dimethoxy-4-methyl-7-{2'-[(2S,3E,5E)-7-methylocta-3,5-dien-2-yl]-2,4'-bi-1,3-thiazol-4-yl}hepta-2,6-dienamide A 2,4'-bi-1,3-thiazole substituted at the 4-position with a (1E,3S,4R,5E)-7-amino-3,5-dimethoxy-4-methyl-7-oxohepta-1,5-dien-1-yl] group and at the 2'-position with a (2S,3E,5E)-7-methylocta-3,5-dien-2-yl group. It is an inhibitor of coenzyme Q - cytochrome c reductase. C25H33N3O3S2 CHEBI:25461 CO[C@@H](\\C=C\\c1csc(n1)-c1csc(n1)C(C)\\C=C\\C=C\\C(C)C)[C@@H](C)C(\\OC)=C/C(N)=O InChI=1/C25H33N3O3S2/c1-16(2)9-7-8-10-17(3)24-28-20(15-33-24)25-27-19(14-32-25)11-12-21(30-5)18(4)22(31-6)13-23(26)29/h7-18,21H,1-6H3,(H2,26,29)/b9-7+,10-8+,12-11+,22-13+/t17?,18-,21+/m1/s1/f/h26H2 InChIKey=XKTFQMCPGMTBMD-WAZGDBOIDY http://www.ebi.ac.uk/efo/EFO_0002672 aldicarb (1E)-2-methyl-2-(methylthio)propanal O-[(methylamino)carbonyl]oxime 116-06-3 2-Methyl-2-(methylthio)propanal, O-((methylamino)carbonyl)oxime 2-Methyl-2-(methylthio)propionaldehyde O-(methylcarbamoyl)oxime 2-Methyl-2-methylthio-propionaldehyd-O-(N-methyl-carbamoyl)-oxim 2-methyl-N-[(methylcarbamoyl)oxy]-2-(methylsulfanyl)propan-1-imine 39 39223 C7 C7H14N2O2S C7H14N2O2S C7[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] CRG-2 CRG-2[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] CXCL10 wt Allele CXCL10 wt Allele[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] Chemokine (C-X-C Motif) Ligand 10 wt Allele Chemokine (C-X-C Motif) Ligand 10 wt Allele[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] Human CXCL10 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine B10 protein, plays a role in both immune cell migration and in the modulation of adhesion molecule expression. Human CXCL10 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine B10 protein, plays a role in both immune cell migration and in the modulation of adhesion molecule expression.[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] IFI10 IFI10[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] INP10 INP10[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] IP-10 IP-10[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] InChI=1/C7H14N2O2S/c1-7(2,12-4)5-9-11-6(10)8-3/h5H,1-4H3,(H,8,10)/f/h8H InChIKey=QGLZXHRNAYXIBU-FZOZFQFYCY MOB-1 MOB-1[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] SCYB10 SCYB10[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] The oxime carbamate resulting from the addition of 2-methyl-2-(methylsulfanyl)propanaldoxime to methyl isocyanate. A member of the class of oxime carbamate insecticides, aldicarb is a mixture of E and Z isomers; it is not known which isomer is more active. [H]C(=NOC(=O)NC)C(C)(C)SC aldicarbe gIP-10 gIP-10[accessedResource: C7H14N2O2S][accessDate: 05-04-2011] alendronic acid (4-Amino-1-hydroxybutylidene)bisphosphonic acid (4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid) 66376-36-1 InChI=1/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12)/f/h7-8,10-11H InChIKey=OGSPWJRAVKPPFI-WMXLOSIUCK NCCCC(O)(P(O)(O)=O)P(O)(O)=O acide alendronique acido alendronico acidum alendronicum alendronate oligomycins CHEBI:25675 http://www.ebi.ac.uk/efo/EFO_0001586 oligomycin organochlorine pesticides 40573 Ocs Organochlorinsektizid chlororganische Insektizide organochlorine insecticide organochlorine insecticides ozone A triatomic oxygen that has formula O3. CHEBI:25812 InChI=1/O3/c1-3-2 InChIKey=CBENFWSGALASAD-UHFFFAOYAY O3 Ozon Trisauerstoff [O-][O+]=O [OO2] http://www.ebi.ac.uk/efo/EFO_0002676 ozono trioxygen trioxygene phosphate 14265-44-2 19672 39672 O4P Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom. phosphate phosphates plant growth regulator A chemical, natural or artificial, that can affect the rate of growth of a plant. CHEBI:26155 James Malone http://www.ebi.ac.uk/efo/EFO_0001900 plant growth regulators phytohormone CHEBI:26158 James Malone http://www.ebi.ac.uk/efo/EFO_0001829 amikacin (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide 1-N-(L(-)-gamma-amino-alpha-hydroxybutyryl)kanamycin A 37517-28-5 An alpha-D-glucoside that has formula C22H43N5O13. C22H43N5O13 InChI=1/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1/f/h27H InChIKey=LKCWBDHBTVXHDL-VLZSSAFWDT NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine amikacina amikacine amikacinum retinoic acid 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid A retinoid that has formula C20H28O2. C20H28O2 CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O CHEBI:26536 InChI=1/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/f/h21H InChIKey=SHGAZHPCJJPHSC-PKSOQXRJCZ http://www.ebi.ac.uk/efo/EFO_0001603 amitriptyline 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene 5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene A tricyclic antidepressant that has formula C20H23N. Amitriptylin C20H23N CHEBI:2666 CN(C)CCC=C1c2ccccc2CCc2ccccc12 InChI=1/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3 InChIKey=KRMDCWKBEZIMAB-UHFFFAOYAI James Malone http://www.ebi.ac.uk/efo/EFO_0001483 sodium chloride A metal chloride salt with a Na(+) counterion. An inorganic sodium salt that has formula ClNa. CHEBI:26710 ClNa InChI=1/ClH.Na/h1H;/q;+1/p-1/fCl.Na/h1h;/q-1;m InChIKey=FAPWRFPIFSIZLT-ZKGBBZBBCO Kochsalz NaCl Natriumchlorid chlorure de sodium cloruro sodico common salt halite http://www.ebi.ac.uk/efo/EFO_0001611 natrii chloridum rock salt salt table salt amoxicillin (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-(p-hydroxy-alpha-aminophenylacetamido)penicillanic acid 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group. A penicillin that has formula C16H19N3O5S. AMPC AX Amolin Amopenixin Amoxicillin anhydrous C16H19N3O5S CHEBI:2676 Clamoxyl InChI=1/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1/f/h18,23H InChIKey=LSQZJLSUYDQPKJ-VLWBPTPADT James Malone Moxal [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccc(O)cc1)C(O)=O alpha-amino-p-hydroxybenzylpenicillin amoxicilina amoxicilline amoxicillinum amoxycillin http://www.ebi.ac.uk/efo/EFO_0002003 p-hydroxyampicillin steroid hormone Any steroid that act as hormone. CHEBI:26764 Gonadal Steroid Hormones Gonadal Steroid Hormones[accessedResource: MSH:D012739][accessDate: 05-04-2011] Hormones, Gonadal Steroid Hormones, Gonadal Steroid[accessedResource: MSH:D012739][accessDate: 05-04-2011] Hormones, Sex Steroid Hormones, Sex Steroid[accessedResource: MSH:D012739][accessDate: 05-04-2011] MSH:D012739 Sex Hormones Sex Hormones[accessedResource: MSH:D012739][accessDate: 05-04-2011] Sex Steroid Hormones Sex Steroid Hormones[accessedResource: MSH:D012739][accessDate: 05-04-2011] Steroid Hormones, Gonadal Steroid Hormones, Gonadal[accessedResource: MSH:D012739][accessDate: 05-04-2011] Steroid Hormones, Sex Steroid Hormones, Sex[accessedResource: MSH:D012739][accessDate: 05-04-2011] Steroid hormones produced by the GONADS. They stimulate reproductive organs, germ cell maturation, and the secondary sex characteristics in the males and the females. The major sex steroid hormones include ESTRADIOL; PROGESTERONE; and TESTOSTERONE. Steroid hormones produced by the GONADS. They stimulate reproductive organs, germ cell maturation, and the secondary sex characteristics in the males and the females. The major sex steroid hormones include ESTRADIOL; PROGESTERONE; and TESTOSTERONE.[accessedResource: MSH:D012739][accessDate: 05-04-2011] Steroidhormon Steroidhormone Tomasz Adamusiak hormona esteroide hormonas esteroideas hormone steroide hormones steroides http://www.ebi.ac.uk/efo/EFO_0001614 steroid hormones amphotericin B (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid 1397-89-3 A macrolide antibiotic used to treat potentially life-threatening fungal infections. AMPH-B Amphotericine B InChI=1/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1/f/h59H InChIKey=APKFDSVGJQXUKY-YQFBPWLTDP Liposomal Amphotericin B [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\\C=C\\C=C\\C=C\\C=C\\C=C\\C=C\\C=C\\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2 amfotericina B amphotericinum B toxin NIFSTD:birnlex_2103 Poisonous substance produced by a biological organism such as a microbe, animal or plant. Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001629 toxins micronutrient CHEBI:27027 James Malone http://www.ebi.ac.uk/efo/EFO_0001830 anastrozole 120511-73-1 2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile) A 1,2,4-triazole compound having a 3,5-bis(2-cyano-2-propyl)benzyl group at the 1-position. Anastrozol C17H19N5 CC(C)(C#N)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N InChI=1/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3 InChIKey=YBBLVLTVTVSKRW-UHFFFAOYAZ alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile Vitamin D CHEBI:27300 Vitamin D is a group of fat-soluble prohormones, which can be obtained from sun exposure, food and supplements. Vitamin D is biologically inactive and converted to the biologically active calcicitriol via double hydroxilation in the body. http://www.ebi.ac.uk/efo/EFO_0001636 true vitamin D3 Zinc 30Zn A zinc group element atom that has formula Zn. A zinc group element that has formula Zn. CHEBI:27363 InChI=1/Zn InChIKey=HCHKCACWOHOZIP-UHFFFAOYAS James Malone Zink [Zn] cinc http://www.ebi.ac.uk/efo/EFO_0001638 zinc atom zincum carbon tetrachloride 56-23-5 A chloromethane that has formula CCl4. CCl4 ClC(Cl)(Cl)Cl InChI=1/CCl4/c2-1(3,4)5 InChIKey=VZGDMQKNWNREIO-UHFFFAOYAV Kohlenstofftetrachlorid Tetra Tetrachlorkohlenstoff Tetrachlormethan tetrachloridocarbon tetrachloromethane mitomycin C (H115D)VHL35 (H115D)VHL35 Peptide 20898 50-07-7 7-Amino-9alpha-methoxymitosane 898 A mitomycin that has formula C15H18N4O5. A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation. (NCI04) Ametycine C15H18N4O5 C15H18N4O5 C15[accessedResource: C15H18N4O5][accessDate: 05-04-2011] Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse. Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse.[accessedResource: C15H18N4O5][accessDate: 05-04-2011] InChI=1/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1/f/h17H2 InChIKey=NWIBSHFKIJFRCO-XPNHIKBZDF MMC Mitocin-C Mitomycin Mutamycin Onzin Onzin[accessedResource: C15H18N4O5][accessDate: 05-04-2011] PLAC8 wt Allele PLAC8 wt Allele[accessedResource: C15H18N4O5][accessDate: 05-04-2011] Placenta-Specific 8 wt Allele Placenta-Specific 8 wt Allele[accessedResource: C15H18N4O5][accessDate: 05-04-2011] [(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate [(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate [H][C@]12CN3C4=C([C@@H](COC(N)=O)[C@@]3(OC)[C@@]1([H])N2)C(=O)C(N)=C(C)C4=O arsenic 23886 33As 3886 7440-38-2 A pnictogen that has formula As. Arsen As InChI=1/As InChIKey=RQNWIZPPADIBDY-UHFFFAOYAR [As] arsenic arsenic atom arsenico arsenicum selenium 34Se A chalcogen that has formula Se. CHEBI:27568 InChI=1/Se InChIKey=BUGBHKTXTAQXES-UHFFFAOYAK James Malone Selen [Se] http://www.ebi.ac.uk/efo/EFO_0001610 selenio selenium atom silicon 14Si A carbon group element atom that has formula Si. A carbon group element that has formula Si. Ele Holloway InChI=1/Si InChIKey=XUIMIQQOPSSXEZ-UHFFFAOYAB James Malone Jie Zheng MO_382 Si Silizium Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#silicon http://www.ebi.ac.uk/efo/EFO_0002420 silicio silicium silicon atom aldosterone (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al A 18-oxo steroid that has formula C21H28O5. A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. C21H28O5 CHEBI:27584 InChI=1/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1 InChIKey=PQSUYGKTWSAVDQ-ZVIOFETBBV [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C=O)C(=O)CO http://www.ebi.ac.uk/efo/EFO_0001479 carbon 6C 7440-44-0 A carbon group element atom that has formula C. C InChI=1/C InChIKey=OKTJSMMVPCPJKN-UHFFFAOYAS Kohlenstoff carbon atom carbone carbonium carbono cycloheximide (H115D)VHL35 (H115D)VHL35 Peptide 24882 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione 4882 66-81-9 A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation. (NCI04) A piperidine antibiotic that has formula C15H23NO4. C15H23NO4 C15H23NO4 C15[accessedResource: C15H23NO4][accessDate: 05-04-2011] CHX Cycloheximid Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse. Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse.[accessedResource: C15H23NO4][accessDate: 05-04-2011] InChI=1/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1/f/h16H InChIKey=YPHMISFOHDHNIV-RFQUBMFVDL Onzin Onzin[accessedResource: C15H23NO4][accessDate: 05-04-2011] PLAC8 wt Allele PLAC8 wt Allele[accessedResource: C15H23NO4][accessDate: 05-04-2011] Placenta-Specific 8 wt Allele Placenta-Specific 8 wt Allele[accessedResource: C15H23NO4][accessDate: 05-04-2011] Zykloheximid [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1 cicloheximida cicloheximidum camptothecin (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (S)-(+)-camptothecin 20(S)-camptothecine 21,22-Secocamptothecin-21-oic acid lactone A pyranoindolizinoquinoline that has formula C20H16N2O4. C20H16N2O4 CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O CHEBI:27656 CPT Camptothecine D-camptothecin InChI=1/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1 InChIKey=VSJKWCGYPAHWDS-FQEVSTJZBY James Malone http://www.ebi.ac.uk/efo/EFO_0001498 actinomycin D 2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis-[(18aS)-10c,14,17-trimethyl-5,8,12,15,18-pentaoxo-6c,13t-di(propan-2-yl)-18ar-hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-9c-yl]-3H-phenoxazine-1,9-dicarboxamide 2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide ActD An actinomycin that has formula C62H86N12O16. C62H86N12O16 CHEBI:27666 Dactinomycin InChI=1/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1/f/h65-68H InChIKey=RJURFGZVJUQBHK-HQANWYOLDQ James Malone [H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)c1ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]6([H])CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc13)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C actinomycin C1 actinomycin IV http://www.ebi.ac.uk/efo/EFO_0001478 Vanadium 23V A vanadium group element atom that has formula V. A vanadium group element that has formula V. CHEBI:27698 InChI=1/V InChIKey=LEONUFNNVUYDNQ-UHFFFAOYAR James Malone [V] http://www.ebi.ac.uk/efo/EFO_0001635 vanadio vanadium atom caffeine 1,3,7-trimethyl-2,6-dioxopurine 1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione 1,3,7-trimethylpurine-2,6-dione 1,3,7-trimethylxanthine 1-methyltheobromine 3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion 58-08-2 7-methyltheophylline A trimethylxanthine that has formula C8H10N4O2. C8H10N4O2 Cn1cnc2n(C)c(=O)n(C)c(=O)c12 Coffein InChI=1/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3 InChIKey=RYYVLZVUVIJVGH-UHFFFAOYAW Koffein MSH:D002110 Thein anhydrous caffeine cafeina cafeine guaranine mateina methyltheobromine teina theine true glyphosate 1071-83-6 24122 4122 A phosphonic acid that has formula C3H8NO5P. C3 Gene C3 Gene[accessedResource: C3H8NO5P][accessDate: 05-04-2011] C3H8NO5P C3H8NO5P C3[accessedResource: C3H8NO5P][accessDate: 05-04-2011] Complement Component 3 Gene Complement Component 3 Gene[accessedResource: C3H8NO5P][accessDate: 05-04-2011] InChI=1/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)/f/h5,7-8H InChIKey=XDDAORKBJWWYJS-JYGMYEITCW N-(phosphonomethyl)glycine OC(=O)CNCP(O)(O)=O This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade. This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade.[accessedResource: C3H8NO5P][accessDate: 05-04-2011] [(phosphonomethyl)amino]acetic acid resveratrol 3,4',5-Trihydroxystilbene 5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol A stilbenol that has formula C14H12O3. C14H12O3 CHEBI:27881 Ele Holloway InChI=1/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H InChIKey=LUKBXSAWLPMMSZ-UHFFFAOYAJ James Malone [H]C(=C([H])c1cc(O)cc(O)c1)c1ccc(O)cc1 http://www.ebi.ac.uk/efo/EFO_0002419 cisplatin (SP-4-2)-diamminedichloridoplatinum (SP-4-2)-diamminedichloroplatinum A platinum-containing anticancer drug that interacts with, and forms cross-links between, DNA and proteins. It is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Briplatin CHEBI:27899 Cismaplat Cl2H6N2Pt H6Cl2N2Pt InChI=1/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2/f2Cl.2H3N.Pt/h2*1h;;;/q2*-1;;;m InChIKey=LXZZYRPGZAFOLE-WMUYXLCICY James Malone Lederplatin Neoplatin Peyrone's chloride Peyrone's salt Platamine Platinex Platinol Randa [H][N]([H])([H])[Pt](Cl)(Cl)[N]([H])([H])[H] cis-DDP cis-[PtCl2(NH3)2] cis-diamminedichloridoplatinum(II) cis-diamminedichloroplatinum cis-diamminedichloroplatinum(II) cis-diammineplatinum(II) dichloride cis-dichlorodiammineplatinum(II) cisplatine cisplatino cisplatinum http://www.ebi.ac.uk/efo/EFO_0001507 tetracycline (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 23645 3645 60-54-8 A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria. A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration. A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration.[accessedResource: C22H24N2O8][accessDate: 05-04-2011] Abramycin Anhydrotetracycline Brassidic Acid Brassidic Acid[accessedResource: C22H24N2O8][accessDate: 05-04-2011] C22:1, n-9 trans C22:1, n-9 trans[accessedResource: C22H24N2O8][accessDate: 05-04-2011] C22H24N2O8 C22H24N2O8 Deschlorobiomycin Fatty Acid 22:1 n-9 trans Fatty Acid 22:1 n-9 trans[accessedResource: C22H24N2O8][accessDate: 05-04-2011] Fatty Acid trans 22:1 n-9 Fatty Acid trans 22:1 n-9[accessedResource: C22H24N2O8][accessDate: 05-04-2011] InChI=1/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1/f/h23H2 InChIKey=OFVLGDICTFRJMM-PZOPXDMEDB Liquamycin Tetracyclin Tetrazyklin Trans docos-13-enoic Acid Trans docos-13-enoic Acid[accessedResource: C22H24N2O8][accessDate: 05-04-2011] Tsiklomitsin [H][C@@]12C[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C tetracyclinum cocaine (1R,2R,3S,5S)-2-(methoxycarbonyl)tropan-3-yl benzoate 2-methyl-3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester) 50-36-2 An alkaloid obtained from leaves of the South American shrub Erythroxylon coca. Benzoylmethylecgonine C17H21NO4 Cocain Cocaina InChI=1/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1 InChIKey=ZPUCINDJVBIVPJ-LJISPDSOBK Kokain Neurocaine [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester [H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)c1ccccc1)C(=O)OC)N2C beta-Cocain cocainum l-Cocain l-cocaine methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate methyl benzoylecgonine 3-methylbenzyl alcohol (3-methylphenyl)methanol 19497 39497 567-03-1 C8H10O CP25 CP25[accessedResource: C8H10O][accessDate: 05-04-2011] Encoded by HOXC6 Gene (ANTP Family), 153- and 235-amino acid (27-kD) Homeobox C6 Protein isoforms are highly conserved sequence-specific DNA-binding homeobox transcription repressors that can cooperate with other HOX proteins and may contribute to the breast cell phenotype through co-operative interactions. As part of a developmental regulatory system that provides anterior-posterior positional identity to cells, HOXC6 may regulate the coordinated expression of multiple genes involved in morphogenesis and differentiation. (from LocusLink, Swiss-Prot, OMIM, and NCI) HHO.C8 HHO.C8[accessedResource: C8H10O][accessDate: 05-04-2011] HOX3C HOX3C[accessedResource: C8H10O][accessDate: 05-04-2011] HOXC6 HOXC6[accessedResource: C8H10O][accessDate: 05-04-2011] Homeobox Protein 3C Homeobox Protein 3C[accessedResource: C8H10O][accessDate: 05-04-2011] Homeobox Protein C6 Homeobox Protein C6[accessedResource: C8H10O][accessDate: 05-04-2011] Homeobox Protein C8 Homeobox Protein C8[accessedResource: C8H10O][accessDate: 05-04-2011] Homeobox Protein CP25 Homeobox Protein CP25[accessedResource: C8H10O][accessDate: 05-04-2011] Homeobox Protein HHO.C8 Homeobox Protein HHO.C8[accessedResource: C8H10O][accessDate: 05-04-2011] Homeobox Protein HOXC6 Homeobox Protein HOXC6[accessedResource: C8H10O][accessDate: 05-04-2011] Homeobox Protein Hox-3C Homeobox Protein Hox-3C[accessedResource: C8H10O][accessDate: 05-04-2011] Homeobox Protein Hox-C6 Homeobox Protein Hox-C6[accessedResource: C8H10O][accessDate: 05-04-2011] Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development. Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development.[accessedResource: C8H10O][accessDate: 05-04-2011] tolbutamide 1-Butyl-3-(p-methylphenylsulfonyl)urea 1-Butyl-3-(p-tolylsulfonyl)urea 1-Butyl-3-tosylurea An urea that has formula C12H18N2O3S. C12H18N2O3S CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 CHEBI:27999 InChI=1/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)/f/h13-14H InChIKey=JLRGJRBPOGGCBT-KGCNKATMCC N-(4-Methylphenylsulfonyl)-N'-butylurea N-Butyl-N'-(4-methylphenylsulfonyl)urea N-Butyl-N'-(p-tolylsulfonyl)urea N-[(butylamino)carbonyl]-4-methylbenzenesulfonamide N-n-Butyl-N'-tosylurea Orinase (TN) http://www.ebi.ac.uk/efo/EFO_0001626 vancomycin (1S,2R,18R,19R,22S,25R,28R,40R)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid (1S,2R,18R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid (2.2Sp,3.5Sa,2.6Sp)-O(4.2),C(3.4):C(5.4),O(4.6):C(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-beta-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-beta-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine] (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid 1404-90-6 22664 42664 A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile. Abutment Abutment[accessedResource: C66H75Cl2N9O24][accessDate: 05-04-2011] C66H75Cl2N9O24 C66H75Cl2N9O24 CN[C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]5NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(O)c(c1)-c1c(O)cc(O)cc1[C@H](NC5=O)C(O)=O)c3O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1)c(Cl)c2 InChI=1/C66H75Cl2N9O24/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95)/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-/m0/s1/f/h72-77,94H,69H2 InChIKey=MYPYJXKWCTUITO-GOYUGWFFDN The tooth, teeth, or implant that supports a fixed bridge or removable prosthesis. The tooth, teeth, or implant that supports a fixed bridge or removable prosthesis.[accessedResource: C66H75Cl2N9O24][accessDate: 05-04-2011] Vancocin vancomicina vancomycine vancomycinum chromium 24Cr A chromium group element atom that has formula Cr. A chromium group element that has formula Cr. CHEBI:28073 Chrom InChI=1/Cr InChIKey=VYZAMTAEIAYCRO-UHFFFAOYAB James Malone [Cr] chrome chromium atom cromo http://www.ebi.ac.uk/efo/EFO_0001505 rifampicin (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1(4,7).0(5,28)]triaconta-1(28),1(29),2,4,9,19,21,25,27-nonaen-13-yl acetate 13292-46-1 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV A N-iminopiperazine that has formula C43H58N4O12. C43H58N4O12 CO[C@H]1\\C=C\\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)\\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\\C=N\\N1CCN(C)CC1)c(O)c4c3C2=O InChI=1/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1/f/h45H InChIKey=JQXXHWHPUNPDRT-SUOBQDSDDO RFP Rifampin rifampicina rifampicinum genistein 4',5,7-trihydroxyisoflavone 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one A hydroxyisoflavone that has formula C15H10O5. A phytoestrogenic isoflavone with antioxidant properties. C15H10O5 CHEBI:28088 InChI=1/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H InChIKey=TZBJGXHYKVUXJN-UHFFFAOYAH James Malone Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O Prunetol Sophoricol http://www.ebi.ac.uk/efo/EFO_0001542 2,3,7,8-tetrachlorodibenzodioxine 2,3,7,8-Tetrachlorodibenzo-p-dioxin 2,3,7,8-Tetrachlorodibenzodioxin 2,3,7,8-tetrachlorooxanthrene A polychlorinated dibenzodioxine that has formula C12H4Cl4O2. C12H4Cl4O2 CHEBI:28119 Clc1cc2Oc3cc(Cl)c(Cl)cc3Oc2cc1Cl Dioxin InChI=1/C12H4Cl4O2/c13-5-1-9-10(2-6(5)14)18-12-4-8(16)7(15)3-11(12)17-9/h1-4H InChIKey=HGUFODBRKLSHSI-UHFFFAOYAA TCDD Tetrachlorodibenzodioxin dioxine http://www.ebi.ac.uk/efo/EFO_0001470 tetradioxin all-cis-docosa-4,7,10,13,16,19-hexaenoic acid (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid 22:6(n-3) 22:6-4, 7,10,13,16,19 A C22, omega-3, polyunsaturated essential fatty acid with double bonds at positions 4, 7, 10, 13, 16 and 19. The most abundant omega-3 fatty acid in the brain and retina, its deficiency is associated with cognitive decline. It is also known to reduce the incidence and severity of a number of diseases. A docosahexaenoic acid that has formula C22H32O2. C22H32O2 CC\\C=C/C\\C=C/C\\C=C/C\\C=C/C\\C=C/C\\C=C/CCC(O)=O CHEBI:28125 DHA DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID Doconexent Docosahexaenoic acid InChI=1/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-/f/h23H InChIKey=MBMBGCFOFBJSGT-YALXRAKKDU all-cis-DHA cervonic acid http://www.ebi.ac.uk/efo/EFO_0001480 ponasterone A (22R)-2beta,3beta,14,20,22-pentahydroxy-5beta-cholest-7-en-6-one 25-Deoxycedysterone A 14alpha-hydroxy steroid that has formula C27H44O6. C27H44O6 CHEBI:28135 InChI=1/C27H44O6/c1-15(2)6-7-23(31)26(5,32)22-9-11-27(33)17-12-19(28)18-13-20(29)21(30)14-24(18,3)16(17)8-10-25(22,27)4/h12,15-16,18,20-23,29-33H,6-11,13-14H2,1-5H3/t16-,18-,20+,21-,22-,23+,24+,25+,26+,27+/m0/s1 InChIKey=PJYYBCXMCWDUAZ-JJJZTNILBL [H][C@]12CC[C@]3(C)[C@]([H])(CC[C@@]3(O)C1=CC(=O)[C@]1([H])C[C@@H](O)[C@@H](O)C[C@]21C)[C@@](C)(O)[C@H](O)CCC(C)C http://www.ebi.ac.uk/efo/EFO_0001594 rotenone (-)-cis-rotenone (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one 5'beta-rotenone A chromenone that has formula C23H22O6. Barbasco C23H22O6 CHEBI:28201 Canex InChI=1/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1 InChIKey=JUVIOZPCNVVQFO-HBGVWJBIBF James Malone Noxfire [2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one [H][C@@]1(Cc2c(O1)ccc1C(=O)[C@@]3([H])c4cc(OC)c(OC)cc4OC[C@@]3([H])Oc21)C(C)=C http://www.ebi.ac.uk/efo/EFO_0001606 methyl mercuric(II) chloride 115-09-3 20813 813 A chlorine molecular entity that has formula CH3ClHg. CH3ClHg CH3ClHg CH3HgCl C[Hg]Cl InChI=1/CH3.ClH.Hg/h1H3;1H;/q;;+1/p-1/fCH3.Cl.Hg/h;1h;/q;-1;m InChIKey=BABMCXWQNSQAOC-IMOFHULNCR MeHg MeHgCl Methylmercury chloride [HgClMe] chloro(methyl)mercury chloro(methyl)mercury chloromethylmercury mercury methyl chloride methylmercuric chloride monomethylmercury chloride dichloroacetate 13425-80-4 C2HCl2O2 InChI=1/C2H2Cl2O2/c3-1(4)2(5)6/h1H,(H,5,6)/p-1/fC2HCl2O2/q-1 InChIKey=JXTHNDFMNIQAHM-LUGZKVCACF [O-]C(=O)C(Cl)Cl dichloracetate dichloroacetate ion dichloroacetic acid ion(1-) dimethyl sulfoxide (CH3)2SO (methanesulfinyl)methane A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. A sulfoxide that has formula C2H6OS. C2H6OS CHEBI:28262 CS(C)=O Dimethylsulfoxid InChI=1/C2H6OS/c1-4(2)3/h1-2H3 InChIKey=IAZDPXIOMUYVGZ-UHFFFAOYAR James Malone S(O)Me2 dimethyl sulfur oxide dimethyl sulphoxide dimethyli sulfoxidum dimethylsulfoxyde dimetil sulfoxido dmso http://www.ebi.ac.uk/efo/EFO_0001523 methylsulfinylmethane sulfinylbis(methane) brassinolide (22R,23R)-2alpha,3alpha,22,23-tetrahydroxy-6,7-seco-5alpha-campestano-6,7-lactone (22R,23R)-2alpha,3alpha,22,23-tetrahydroxy-7a-homo-7-oxa-5alpha-campestan-6-one A 2alpha-hydroxy steroid that has formula C28H48O6. A brassinosteroid that has formula C28H48O6. C28H48O6 CHEBI:28277 Ele Holloway InChI=1/C28H48O6/c1-14(2)15(3)24(31)25(32)16(4)18-7-8-19-17-13-34-26(33)21-11-22(29)23(30)12-28(21,6)20(17)9-10-27(18,19)5/h14-25,29-32H,7-13H2,1-6H3/t15-,16-,17-,18+,19-,20-,21+,22-,23+,24+,25+,27+,28+/m0/s1 InChIKey=IXVMHGVQKLDRKH-KNBKMWSGBW James Malone [H][C@@]1(CC[C@@]2([H])[C@]3([H])COC(=O)[C@@]4([H])C[C@H](O)[C@H](O)C[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)[C@@H](O)[C@H](O)[C@@H](C)C(C)C http://www.ebi.ac.uk/efo/EFO_0002401 oligomycin A CHEBI:28285 http://www.ebi.ac.uk/efo/EFO_0001585 glutamine 2,5-diamino-5-oxopentanoic acid 2-Aminoglutaramic acid 2-amino-4-carbamoylbutanoic acid An alpha-amino acid that has formula C5H10N2O3. C5H10N2O3 CHEBI:28300 Glutamin Glutaminsaeure-5-amid Hgln InChI=1/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/f/h9H,7H2 InChIKey=ZDXPYRJPNDTMRX-HDAMEQSMCZ NC(CCC(N)=O)C(O)=O glutamic acid gamma-amide http://www.ebi.ac.uk/efo/EFO_0001546 all-cis-icosa-5,8,11,14,17-pentaenoic acid (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic acid (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoate (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid (all-Z)-5,8,11,14,17-eicosapentaenoic acid 10417-94-4 11-Eicosenoic Acid 11-Eicosenoic Acid[accessedResource: C20H30O2][accessDate: 05-04-2011] 21023 41023 5,8,11,14,17-EICOSAPENTAENOIC ACID 5,8,11,14,17-Icosapentaenoic acid A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration. A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration.[accessedResource: C20H30O2][accessDate: 05-04-2011] An eicosapentaenoic acid having cis double bonds at positions 5, 8, 11, 14 and 17. An icosapentaenoic acid that has formula C20H30O2. C20:1 n-9 cis C20:1 n-9 cis[accessedResource: C20H30O2][accessDate: 05-04-2011] C20H30O2 C20H30O2 CC\\C=C/C\\C=C/C\\C=C/C\\C=C/C\\C=C/CCCC(O)=O Cis-icos-11-enoic Cis-icos-11-enoic[accessedResource: C20H30O2][accessDate: 05-04-2011] EPA EPA; eicosapentaenoic acid Eicosapentaenoic acid Fatty Acid 20:1 n-9 Fatty Acid 20:1 n-9[accessedResource: C20H30O2][accessDate: 05-04-2011] Gondoic Acid Gondoic Acid[accessedResource: C20H30O2][accessDate: 05-04-2011] InChI=1/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-/f/h21H InChIKey=JAZBEHYOTPTENJ-IQFRBLEYDZ Timnodonic acid all-cis-5,8,11,14,17-eicosapentaenoic acid cis-5,8,11,14,17-eicosapentaenoic acid cis-Delta(5,8,11,14,17)-eicosapentaenoic acid icosapent icosapento icosapentum novobiocin CHEBI:28368 http://www.ebi.ac.uk/efo/EFO_0001583 vincristine 22-Oxovincaleukoblastine A vinca alkaloid that has formula C46H56N4O10. C46H56N4O10 CHEBI:28445 Ele Holloway InChI=1/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1 InChIKey=OGWKCGZFUXNPDA-XQKSVPLYBW James Malone [H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C=O)[C@@]1([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]1(C[C@@H]2C[N@](CCc3c1[nH]c1ccccc31)C[C@](O)(CC)C2)C(=O)OC http://www.ebi.ac.uk/efo/EFO_0002421 leurocristine acrylamide 2-Propenamide 20027 27 79-06-1 A member of the acrylamides that has formula C3H5NO. Akrylamid C3 Gene C3 Gene[accessedResource: C3H5NO][accessDate: 05-04-2011] C3H5NO C3H5NO C3[accessedResource: C3H5NO][accessDate: 05-04-2011] Complement Component 3 Gene Complement Component 3 Gene[accessedResource: C3H5NO][accessDate: 05-04-2011] InChI=1/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)/f/h4H2 InChIKey=HRPVXLWXLXDGHG-LGEMBHMGCJ NC(=O)C=C This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade. This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade.[accessedResource: C3H5NO][accessDate: 05-04-2011] acrylamide ethylenecarboxamide prop-2-enamide lipoteichoic Acid 40534 56411-57-5 A teichoic acid which is covalently bound to a lipid. leukotriene D4 (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)glycine 11q23.1-q23.2 11q23.1-q23.2[accessedResource: C25H40N2O6S][accessDate: 05-04-2011] 20533 40533 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-eicosatetraenoic acid 73836-78-9 A chromosome band present on 11q A chromosome band present on 11q[accessedResource: C25H40N2O6S][accessDate: 05-04-2011] A leukotriene that has formula C25H40N2O6S. C25H40N2O6S C25H40N2O6S CCCCC\\C=C/C\\C=C/C=C/C=C/[C@@H](SC[C@H](N)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O InChI=1/C25H40N2O6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(28)15-14-17-23(29)30)34-19-20(26)25(33)27-18-24(31)32/h6-7,9-13,16,20-22,28H,2-5,8,14-15,17-19,26H2,1H3,(H,27,33)(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t20-,21-,22+/m0/s1/f/h27,29,31H InChIKey=YEESKJGWJFYOOK-MBFKQSLNDJ LTD4 S-[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxynonadeca-6,8,10,13-tetraen-5-yl]cysteinylglycine S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinylglycine cytarabine 1-beta-D-Arabinofuranosylcytosine 10-Deacetyltaxol 147-94-4 22877 2877 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one A pyrimidine nucleoside that has formula C9H13N3O5. A series of reactions that result in formation of a pore, composed of complement proteins C5b, C6, C7, C8, and C9, in the membrane of a pathogenic cell. The pore allows free diffusion of molecules into and out of the cell and reduces cell viability. A series of reactions that result in formation of a pore, composed of complement proteins C5b, C6, C7, C8, and C9, in the membrane of a pathogenic cell. The pore allows free diffusion of molecules into and out of the cell and reduces cell viability.[accessedResource: C9H13N3O5][accessDate: 05-04-2011] Activation of Membrane Attack Complex Activation of Membrane Attack Complex[accessedResource: C9H13N3O5][accessDate: 05-04-2011] An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis. C9H13N3O5 C9H13N3O5 Cytosine arabinoside Cytosine-1-beta-D-arabinofuranoside InChI=1/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1/f/h10H2 InChIKey=UHDGCWIWMRVCDJ-JEMZYTBMDI Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1 benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))- cytosine arabinoside; Ara-C copper 29Cu A copper group element atom that has formula Cu. A copper group element that has formula Cu. CHEBI:28694 Cu Ele Holloway InChI=1/Cu InChIKey=RYGMFSIKBFXOCR-UHFFFAOYAN James Malone Kupfer cobre copper atom cuivre cuprum http://www.ebi.ac.uk/efo/EFO_0002406 doxorubicin (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside (8S-cis)-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione 14-hydroxydaunomycin 14-hydroxydaunorubicine A deoxy hexoside that has formula C27H29NO11. Adriamycin C27H29NO11 CHEBI:28748 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO InChI=1/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1 InChIKey=AOJJSUZBOXZQNB-TZSSRYMLBG doxorubicine doxorubicinum http://www.ebi.ac.uk/efo/EFO_0001527 (2,4-dichlorophenoxy)acetic acid (2,4-Dichlorphenoxy)essigsaeure (2,4-dichlorophenoxy)acetic acid 2,4-D 2,4-D; 2,4-dichlorophenoxyacetic acid 2,4-Dichlorophenoxyacetate 2,4-Dichlorophenoxyacetic acid 20442 442 94-75-7 A chlorophenoxyacetic acid that has formula C8H6Cl2O3. C8H6Cl2O3 C8H6Cl2O3 CP25 CP25[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Encoded by HOXC6 Gene (ANTP Family), 153- and 235-amino acid (27-kD) Homeobox C6 Protein isoforms are highly conserved sequence-specific DNA-binding homeobox transcription repressors that can cooperate with other HOX proteins and may contribute to the breast cell phenotype through co-operative interactions. As part of a developmental regulatory system that provides anterior-posterior positional identity to cells, HOXC6 may regulate the coordinated expression of multiple genes involved in morphogenesis and differentiation. (from LocusLink, Swiss-Prot, OMIM, and NCI) HHO.C8 HHO.C8[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] HOX3C HOX3C[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] HOXC6 HOXC6[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Hedonal Homeobox Protein 3C Homeobox Protein 3C[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Homeobox Protein C6 Homeobox Protein C6[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Homeobox Protein C8 Homeobox Protein C8[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Homeobox Protein CP25 Homeobox Protein CP25[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Homeobox Protein HHO.C8 Homeobox Protein HHO.C8[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Homeobox Protein HOXC6 Homeobox Protein HOXC6[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Homeobox Protein Hox-3C Homeobox Protein Hox-3C[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Homeobox Protein Hox-C6 Homeobox Protein Hox-C6[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development. Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development.[accessedResource: C8H6Cl2O3][accessDate: 05-04-2011] InChI=1/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)/f/h11H InChIKey=OVSKIKFHRZPJSS-WXRBYKJCCM OC(=O)COc1ccc(Cl)cc1Cl Trinoxol tobramycin (1S,2S,3R,4S,6R)-4,6-diamino-3-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside (1S,2S,3R,4S,6R)-4,6-diamino-3-[(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyl)oxy]-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside 23680 3'-Deoxykanamycin B 32986-56-4 C18H37N5O9 C18H37N5O9 EFABP EFABP[accessedResource: C18H37N5O9][accessDate: 05-04-2011] Epidermal Fatty Acid-Binding Protein Epidermal Fatty Acid-Binding Protein[accessedResource: C18H37N5O9][accessDate: 05-04-2011] Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI) Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI)[accessedResource: C18H37N5O9][accessDate: 05-04-2011] FABP5 FABP5[accessedResource: C18H37N5O9][accessDate: 05-04-2011] Fatty Acid Binding Protein 5 Fatty Acid Binding Protein 5[accessedResource: C18H37N5O9][accessDate: 05-04-2011] InChI=1/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1 InChIKey=NLVFBUXFDBBNBW-PBSUHMDJBB NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O Nebramycin 6 Nebramycin factir 6 O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine PAFABP PAFABP[accessedResource: C18H37N5O9][accessDate: 05-04-2011] Tobracin (TN) Tobrex (TN) butan-1-ol 1-butyl alcohol 1-hydroxybutane 1740 21740 71-36-3 An alkyl alcohol that has formula C4H10O. BuOH C4H10O C4H10O C4[accessedResource: C4H10O][accessDate: 05-04-2011] CCCCO Complement C4 Complement C4 Measurement Complement C4 Measurement[accessedResource: C4H10O][accessDate: 05-04-2011] Complement C4[accessedResource: C4H10O][accessDate: 05-04-2011] Complement Component-4 Complement component-4 (1744 aa, ~193 kDa) is part of the complement cascade, which mediates the innate immune response to infection. The full length protein is a precursor that can is secreted as a trimeric molecule containing an alpha, beta and gamma chain. When the complement cascade is initiated, the protein is cleaved. This proteolysis releases both the alpha chain, C4 anaphylatoxin, which stimulates inflammation, and a dimer of the beta and gamma chains, which mediates the interaction between the antigen-antibody complex and other complement components. InChI=1/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H3 InChIKey=LRHPLDYGYMQRHN-UHFFFAOYAS The determination of the amount of complement C4 present in a sample. The determination of the amount of complement C4 present in a sample.[accessedResource: C4H10O][accessDate: 05-04-2011] butan-1-ol butanol; 1-butanol n-Butanol n-Butylalkohol n-butan-1-ol n-butyl alcohol propyl carbinol 3-aminophenol 24497 3-aminophenol 4497 591-27-5 C6 Vertebra C6 Vertebra[accessedResource: C6H7NO][accessDate: 05-04-2011] C6H7NO C6H7NO InChI=1/C6H7NO/c7-5-2-1-3-6(8)4-5/h1-4,8H,7H2 InChIKey=CWLKGDAVCFYWJK-UHFFFAOYAM Nc1cccc(O)c1 The one of three amino derivatives of phenol which has the single amino substituent located meta to the phenolic -OH group. The sixth of the seven cervical vertebrae. The sixth of the seven cervical vertebrae.[accessedResource: C6H7NO][accessDate: 05-04-2011] m-Aminophenol m-hydroxyaniline N-acetyl-L-cysteine (2R)-2-acetylamino-3-sulfanylpropanoic acid (R)-2-acetylamino-3-mercaptopropanoic acid (R)-mercapturic acid Acetylcysteine An acetylcysteine that has formula C5H9NO3S. C5H9NO3S CC(=O)N[C@@H](CS)C(O)=O CHEBI:28939 InChI=1/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1/f/h6,8H InChIKey=PWKSKIMOESPYIA-JVBVHTJODB L-acetylcysteine L-alpha-acetamido-beta-mercaptopropionic acid N-acetylcysteine The N-acetylated derivative of natural amino acid L-cysteine. acetilcisteina acetylcysteinum http://www.ebi.ac.uk/efo/EFO_0001576 mercapturic acid calciol (+)-vitamin D3 (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol (3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol 67-97-0 A seco-cholestane that has formula C27H44O. A vitamin D that has formula C27H44O. C27H44O CC Cholecalciferol InChI=1/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1 InChIKey=QYSXJUFSXHHAJI-YRZJJWOYBL [H][C@@]1(CC[C@]2([H])[C@]1(C)CCC\\C2=C/C=C1/C[C@@H](O)CCC1=C)[C@H](C)CCCC(C)C activated 7-dehydrocholesterol colecalciferol oleovitamin D3 ampicillin (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-(D-(2-amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 69-53-4 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylic acid A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group. ABPC AMP AP Anhydrous ampicillin C16H19N3O4S D-(-)-6-(alpha-aminophenylacetamido)penicillanic acid D-(-)-ampicillin InChI=1/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1/f/h18,22H InChIKey=AVKUERGKIZMTKX-KXDAXDHGDU [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O aminobenzylpenicillin ampicilina ampicillin acid ampicilline ampicillinum aluminium 13Al A boron group element atom that has formula Al. A boron group element that has formula Al. CHEBI:28984 Ele Holloway InChI=1/Al InChIKey=XAGFODPZIPBFFR-UHFFFAOYAX James Malone [Al] aluminio aluminium atom aluminum http://www.ebi.ac.uk/efo/EFO_0002399 ceftriaxone (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 73384-59-5 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid A cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side groups. C18H18N8O7S3 InChI=1/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1/f/h21,23,31H,19H2 InChIKey=VAAUVRVFOQPIGI-MPSLXNHQDN [H][C@]12SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1csc(N)n1)C(O)=O ceftriaxona ceftriaxonum N-benzyladenine 6-(benzylamino)purine 6-BAP 6-[(phenylmethyl)amino]-9H-purine A 6-aminopurine that has formula C12H11N5. BAP C(Nc1ncnc2[nH]cnc12)c1ccccc1 C12H11N5 CHEBI:29022 Cytokinin B InChI=1/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)/f/h13,15H InChIKey=NWBJYWHLCVSVIJ-YENFCIRVCT N(6)-(benzylamino)purine N-BENZYL-9H-PURIN-6-AMINE N6-Benzyladenine benzyladenine http://www.ebi.ac.uk/efo/EFO_0001577 L-ascorbic acid (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one 50-81-7 An ascorbic acid that has formula C6H8O6. Ascoltin Ascorbicap Ascorbinsaeure C6H8O6 InChI=1/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 InChIKey=CIWBSHSKHKDKBQ-JLAZNSOCBT L-Ascorbate L-threo-hex-2-enono-1,4-lactone The L- enatiomer of ascorbic acid and conjugate acid of L-ascorbate; an essential nutrient and antioxidant with possible anticancer role, especially with intravenous administration. A cofactor in several enzymatic reactions of living organisms, it is linked with effective wound healing and prevention or treatment of scurvy and gout. Also known as vitamin C, it is believed to boost the immune system. Humans alone of the primates require exogenous sources of daily vitamin C. Vitamin C [H][C@@]1(OC(=O)C(O)=C1O)[C@@H](O)CO acide ascorbique acido ascorbico acidum ascorbicum acidum ascorbinicum ascorbic acid calcium(2+) 14127-61-8 17638 37638 A calcium cation that has formula Ca. CALCIUM ION Ca Ca Ca(2+) Ca2+ InChI=1/Ca/q+2 InChIKey=BHPQYMZQTOCNFJ-UHFFFAOYAP calcium calcium(2+) ion calcium(II) cation calcium, doubly charged positive ion calcium sodium nitroprusside 14402-89-2 16794 36794 An organic sodium salt that has formula C5FeN6Na2O. C5 C5 Gene C5 Gene[accessedResource: C5FeN6Na2O][accessDate: 05-04-2011] C5FeN6Na2O C5FeN6Na2O C5[accessedResource: C5FeN6Na2O][accessDate: 05-04-2011] Complement Component 5 Gene Complement Component 5 Gene[accessedResource: C5FeN6Na2O][accessDate: 05-04-2011] Human C5 wild-type allele is located within 9q33-q34 and is approximately 98 kb in length. This allele, which encodes complement C5 protein, is involved in the complement system, inflammatory responses, and histamine release. Human C5 wild-type allele is located within 9q33-q34 and is approximately 98 kb in length. This allele, which encodes complement C5 protein, is involved in the complement system, inflammatory responses, and histamine release.[accessedResource: C5FeN6Na2O][accessDate: 05-04-2011] InChI=1/5CN.Fe.NO.2Na/c5*1-2;;1-2;;/q;;;;;2*-1;2*+1 InChIKey=FPWUWQVZUNFZQM-UHFFFAOYAO Na2[Fe(CN)5(NO)] SNP Sodium nitroprusside anhydrous Sodium pentacyanonitrosylferrate [Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N disodium pentacyanidonitrosylferrate sodium pentacyanidonitrosylferrate(2-) sodium pentacyanidonitrosylferrate(III) azathioprine 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine A thiopurine that has formula C9H7N7O2S. C9H7N7O2S CHEBI:2948 Cn1cnc(c1Sc1ncnc2nc[nH]c12)[N+]([O-])=O Imuran (TN) InChI=1/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)/f/h10H InChIKey=LMEKQMALGUDUQG-KZFATGLACK James Malone http://www.ebi.ac.uk/efo/EFO_0001491 azithromycin (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one 10760 10q24.1-q25.1 10q24.1-q25.1[accessedResource: C38H72N2O12][accessDate: 05-04-2011] 30760 83905-01-5 A chromosome band present on 10q A chromosome band present on 10q[accessedResource: C38H72N2O12][accessDate: 05-04-2011] AZM Azenil Azifast Azigram Azimakrol Azitromin C38H72N2O12 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O Hemomycin InChI=1/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1 InChIKey=MQTOSJVFKKJCRP-BICOPXKEBK Zithromax Zmax aritromicina azithromycine azithromycinum baicalin 21967-41-9 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acid 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid 7-D-glucuronic acid-5,6-dihydroxyflavone Baicalein 7-O-glucuronide InChI=1/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1/f/h28H InChIKey=IKIIZLYTISPENI-LAONJVSMDB O[C@H]1[C@@H](O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O)Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 The glycosyloxyflavone which is the 7-O-glucuronide of baicalein. benzo(a)pyrene (B(a)P) 11-Eicosenoic Acid 11-Eicosenoic Acid[accessedResource: C20H12][accessDate: 05-04-2011] 139 20139 3,4-BP 3,4-Benzopyrene 3,4-Benzpyrene 50-32-8 A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration. A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration.[accessedResource: C20H12][accessDate: 05-04-2011] An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. BP BaP Benzo[a]pyrene Benzpyrene C20:1 n-9 cis C20:1 n-9 cis[accessedResource: C20H12][accessDate: 05-04-2011] C20H12 C20H12 Cis-icos-11-enoic Cis-icos-11-enoic[accessedResource: C20H12][accessDate: 05-04-2011] Fatty Acid 20:1 n-9 Fatty Acid 20:1 n-9[accessedResource: C20H12][accessDate: 05-04-2011] Gondoic Acid Gondoic Acid[accessedResource: C20H12][accessDate: 05-04-2011] InChI=1/C20H12/c1-2-7-17-15(4-1)12-16-9-8-13-5-3-6-14-10-11-18(17)20(16)19(13)14/h1-12H InChIKey=FMMWHPNWAFZXNH-UHFFFAOYAQ benzo[def]chrysene benzo[pqr]tetraphene benzo[pqr]tetraphene c1ccc2c(c1)cc1ccc3cccc4ccc2c1c34 arsenite(3-) 15502-74-6 ARSENITE An arsenite ion that has formula AsO3. As(III); arsenite AsO3 AsO3(3-) InChI=1/AsO3/c2-1(3)4/q-3 InChIKey=OWTFKEBRIAXSMO-UHFFFAOYAC [O-][As]([O-])[O-] arsorite trioxidoarsenate(3-) trioxoarsenate(3-) trioxoarsenate(III) acetate ACETATE ION Azetat C2H3O2 CC([O-])=O CH3-COO(-) Ethanoat InChI=1/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1/fC2H3O2/q-1 InChIKey=QTBSBXVTEAMEQO-KSORUIRRCC MeCO2 anion The conjugate base of acetic acid. acetic acid, ion(1-) ethanoate aluminium trichloride 29674 7446-70-0 9674 AlCl3 Aluminum chloride anhydrous Aluminum trichloride An aluminium coordination entity that has formula AlCl3. Cl[Al](Cl)Cl InChI=1/Al.3ClH/h;3*1H/q+3;;;/p-3/fAl.3Cl/h;3*1h/qm;3*-1 InChIKey=VSCWAEJMTAWNJL-GZMOREBICG [AlCl3] aluminium(3+) chloride aluminium(III) chloride aluminum trichloride trichloridoaluminium trichloroalumane benomyl 1-(Butylcarbamoyl)-2-benzimidazol-methylcarbamat 1-(N-Butylcarbamoyl)-2-(methoxy-carboxamido)-benzimidazol 17804-35-2 23900 A benzimidazolamine pesticide that has formula C14H18N4O3. A radiolabelled urea molecule used to diagnose stomach ulcers caused by Heliobacter pylori. In the presence of H. pylori, urea C-14 is metabolized by urease to produce ammonia and radioactive carbon dioxide at the interface between the gastric epithelium and lumen. The radioactive carbon dioxide is absorbed in the blood and is detected when exhaled in the breath. A radiolabelled urea molecule used to diagnose stomach ulcers caused by Heliobacter pylori. In the presence of H. pylori, urea C-14 is metabolized by urease to produce ammonia and radioactive carbon dioxide at the interface between the gastric epithelium and lumen. The radioactive carbon dioxide is absorbed in the blood and is detected when exhaled in the breath.[accessedResource: C14H18N4O3][accessDate: 05-04-2011] Benlate C14 Urea C14 Urea[accessedResource: C14H18N4O3][accessDate: 05-04-2011] C14H18N4O3 C14H18N4O3 CCCCNC(=O)n1c(NC(=O)OC)nc2ccccc12 InChI=1/C14H18N4O3/c1-3-4-9-15-13(19)18-11-8-6-5-7-10(11)16-12(18)17-14(20)21-2/h5-8H,3-4,9H2,1-2H3,(H,15,19)(H,16,17,20)/f/h15,17H InChIKey=RIOXQFHNBCKOKP-KJQBJTEXCD Pytest Pytest[accessedResource: C14H18N4O3][accessDate: 05-04-2011] UREA, C-14 UREA, C-14[accessedResource: C14H18N4O3][accessDate: 05-04-2011] Urea C-14 Urea C-14[accessedResource: C14H18N4O3][accessDate: 05-04-2011] methyl [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamate methyl {1-[(butylamino)carbonyl]-1H-benzimidazol-2-yl}carbamate 2,2'-bipyridine 2,2'-Bipyridin 2,2'-bipyridyl 2,2'-dipyridine 2,2'-dipyridyl 2-(2-pyridyl)pyridine A bipyridine that has formula C10H8N2. C10H8N2 CHEBI:30351 Ele Holloway InChI=1/C10H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12-10/h1-8H InChIKey=ROFVEXUMMXZLPA-UHFFFAOYAP Tomasz Adamusiak alpha,alpha'-bipyridine alpha,alpha'-bipyridyl alpha,alpha'-dipyridine alpha,alpha'-dipyridyl bpy c1ccc(nc1)-c1ccccn1 http://www.ebi.ac.uk/efo/EFO_0002723 benzo(a)pyrene diolepoxide 1 11-Eicosenoic Acid 11-Eicosenoic Acid[accessedResource: C20H14O3][accessDate: 05-04-2011] 16779 36779 58917-67-2 7,8,8a,9a-tetrahydrobenzo[1,12]tetrapheno[10,11-b]oxirene-7,8-diol 7,8,8a,9a-tetrahydrobenzo[1,12]tetrapheno[10,11-b]oxirene-7,8-diol 7,8,8a,9a-tetrahydrobenzo[10,11]chryseno[3,4-b]oxirene-7,8-diol A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration. A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration.[accessedResource: C20H14O3][accessDate: 05-04-2011] An epoxide that has formula C20H14O3. BDPE BP 7,8-Diol-9,10-epoxide 2 BPDE Benzo(a)pyrene diol epoxide C20:1 n-9 cis C20:1 n-9 cis[accessedResource: C20H14O3][accessDate: 05-04-2011] C20H14O3 C20H14O3 Cis-icos-11-enoic Cis-icos-11-enoic[accessedResource: C20H14O3][accessDate: 05-04-2011] Fatty Acid 20:1 n-9 Fatty Acid 20:1 n-9[accessedResource: C20H14O3][accessDate: 05-04-2011] Gondoic Acid Gondoic Acid[accessedResource: C20H14O3][accessDate: 05-04-2011] InChI=1/C20H14O3/c21-17-13-8-11-5-4-9-2-1-3-10-6-7-12(15(11)14(9)10)16(13)19-20(23-19)18(17)22/h1-8,17-22H InChIKey=DQEPMTIXHXSFOR-UHFFFAOYAD OC1C(O)c2cc3ccc4cccc5ccc(c2C2OC12)c3c45 benzo[a]pyrene diol epoxide I ethylene glycol 1,2-Dihydroxyethane 1,2-Ethanediol 107-21-1 2-Hydroxyethanol 20597 597 A 1,2-glycol compound produced via reaction of ethylene oxide with water. C2 Mouse C2 Mouse[accessedResource: C2H6O2][accessDate: 05-04-2011] C2H6O2 C2H6O2 C2[accessedResource: C2H6O2][accessDate: 05-04-2011] Ethane-1,2-diol Ethanediol Glycol HO-CH2-CH2-OH InChI=1/C2H6O2/c3-1-2-4/h3-4H,1-2H2 InChIKey=LYCAIKOWRPUZTN-UHFFFAOYAD Monoethylene glycol OCCO ethylene glycol benzoic acid 143 20143 65-85-0 A compound comprising a benzene ring core carrying a carboxylic acid substituent. Benzenecarboxylic acid Benzoesaeure C7 C7H6O2 C7H6O2 C7[accessedResource: C7H6O2][accessDate: 05-04-2011] CRG-2 CRG-2[accessedResource: C7H6O2][accessDate: 05-04-2011] CXCL10 wt Allele CXCL10 wt Allele[accessedResource: C7H6O2][accessDate: 05-04-2011] Chemokine (C-X-C Motif) Ligand 10 wt Allele Chemokine (C-X-C Motif) Ligand 10 wt Allele[accessedResource: C7H6O2][accessDate: 05-04-2011] Dracylic acid Human CXCL10 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine B10 protein, plays a role in both immune cell migration and in the modulation of adhesion molecule expression. Human CXCL10 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine B10 protein, plays a role in both immune cell migration and in the modulation of adhesion molecule expression.[accessedResource: C7H6O2][accessDate: 05-04-2011] IFI10 IFI10[accessedResource: C7H6O2][accessDate: 05-04-2011] INP10 INP10[accessedResource: C7H6O2][accessDate: 05-04-2011] IP-10 IP-10[accessedResource: C7H6O2][accessDate: 05-04-2011] InChI=1/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)/f/h8H InChIKey=WPYMKLBDIGXBTP-FZOZFQFYCI MOB-1 MOB-1[accessedResource: C7H6O2][accessDate: 05-04-2011] OC(=O)c1ccccc1 Phenylformic acid SCYB10 SCYB10[accessedResource: C7H6O2][accessDate: 05-04-2011] acide benzoique benzoic acid gIP-10 gIP-10[accessedResource: C7H6O2][accessDate: 05-04-2011] bicalutamide (2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide An amide that has formula C18H14F4N2O4S. C18H14F4N2O4S CHEBI:3090 C[C@](O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F C[C@](O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C#N)c(c2)C(F)(F)F Casodex InChI=1/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)/t17-/m0/s1/f/h24H InChIKey=LKJPYSCBVHEWIU-ARSKLOKFDL James Malone bicalutamida bicalutamidum http://www.ebi.ac.uk/efo/EFO_0002006 glucitol C6H14O6 CHEBI:30911 Sorbitol gulitol http://www.ebi.ac.uk/efo/EFO_0001543 rel-(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol bicuculline (6R)-6-[(5S)-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one Bicculine Bicucullin Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. C20H17NO6 CHEBI:3092 Ele Holloway InChI=1/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1 InChIKey=IYGYMKDQCDOMRE-ZWKOTPCHBP Tomasz Adamusiak [H][C@]1(OC(=O)c2c3OCOc3ccc12)[C@@]1([H])N(C)CCc2cc3OCOc3cc12 d-Bicuculline http://www.ebi.ac.uk/efo/EFO_0002725 carboplatin (SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa(2)O,O']platinum A platinum coordination entity that has formula C6H12N2O4Pt. C6H12N2O4Pt C6H6O4Pt.2H3N InChI=1/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2/p-2/fC6H6O4.2H3N.Pt/q-2;;;m InChIKey=OLESAACUTLOWQZ-DRGNIJNRCF Paraplatin [H][N]([H])([H])[Pt]1(OC(=O)C2(CCC2)C(=O)O1)[N]([H])([H])[H] cbdca cis-(1,1-cyclobutanedicarboxylato)diammineplatinum(II) cis-diammine(1,1-cyclobutanedicarboxylato)platinum cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II) bleomycin A2 (betaR)-N(alpha)-{[6-amino-2-((1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl)-5-methylpyrimidin-4-yl]carbonyl}-beta-{2-O-[3-O-(aminocarbonyl)-alpha-D-mannopyranosyl]-alpha-L-gulopyranosyloxy}-N-[(1R,2S,3S)-5-({(1S,2R)-1-[({2-[4-({[3-(dimethylsulfonio)propyl]amino}carbonyl)-2,4'-bi-1,3-thiazol-2'-yl]ethyl}amino)carbonyl]-2-hydroxypropyl}amino)-3-hydroxy-4-methyl-5-oxopentan-2-yl]-L-histidinamide A bleomycin that has formula C55H84N17O21S3. Bleomycin C55H84N17O21S3 CHEBI:3139 InChI=1/C55H83N17O21S3/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88)/p+1/t21-,22+,23+,24-,25-,29-,30+,34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,53+,54-/m0/s1/fC55H84N17O21S3/h61-63,66,70-71H,57-60H2/q+1 InChIKey=OYVAGSVQBOHSSS-IIMGSDJHDB N(1)-[3-(dimethylsulfonio)propyl]bleomycinamide [H][C@](C)(NC(=O)[C@@]([H])(NC(=O)c1nc(nc(N)c1C)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)[C@@]([H])(O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)c1c[nH]cn1)[C@@H](O)[C@H](C)C(=O)N[C@]([H])(C(=O)NCCc1nc(cs1)-c1nc(cs1)C(=O)NCCC[S+](C)C)[C@@]([H])(C)O http://www.ebi.ac.uk/efo/EFO_0001494 true fasudil hydrochloride CHEBI:31593 Ele Holloway James Malone http://www.ebi.ac.uk/efo/EFO_0002407 fulvestrant 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol A 3-hydroxy steroid that has formula C32H47F5O3S. C32H47F5O3S CHEBI:31638 InChI=1/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29?,30+,41?/m1/s1 InChIKey=VWUXBMIQPBEWFH-LQKBAPIOBA James Malone [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])C1[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc4cc(O)ccc24 http://www.ebi.ac.uk/efo/EFO_0001540 kainic acid (2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid (3S,4R)-3-(carboxymethyl)-4-(prop-1-en-2-yl)-L-proline A pyrrolidinemonocarboxylic acid that has formula C10H15NO4. CC(=C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O CHEBI:31746 Digenin Digensaeure Helminal InChI=1/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1/f/h12,14H InChIKey=VLSMHEGGTFMBBZ-WODSAOQMDB James Malone Kainsaeure L-alpha-kainic acid acide kainique acido kainico acidum kainicum alpha-Kainic acid digenic acid http://www.ebi.ac.uk/efo/EFO_0001561 bromocriptine methanesulfonate (5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-2'-(propan-2-yl)-3',6',18-trioxoergotaman methanesulfonate (5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-3',6',18-trioxo-2'-(propan-2-yl)ergotaman methanesulfonate (salt) (5'alpha)-2-bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman methanesulfonate 2-bromo-alpha-ergocryptine mesylate 20197 22260-51-1 4F9 4F9[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] A methanesulfonate salt that has formula C33H44BrN5O8S. C32H40BrN5O5.CH4O3S C33 C33H44BrN5O8S C33H44BrN5O8S C33[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] CD82 CD82 Antigen wt Allele CD82 Antigen wt Allele[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] CD82 wt Allele CD82 wt Allele[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] CD82[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] CS(O)(=O)=O.[H][C@@]12Cc3c(Br)[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N[C@@]1(O[C@]2(O)N([C@@H](CC(C)C)C(=O)N5CCC[C@@]25[H])C1=O)C(C)C)c34 GR15 GR15[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] Human CD82 wild-type allele is located in the vicinity of 11p11.2 and is approximately 54 kb in length. This allele, which encodes CD82 antigen Immunoprotein, is involved in metastasis suppression. Human CD82 wild-type allele is located in the vicinity of 11p11.2 and is approximately 54 kb in length. This allele, which encodes CD82 antigen Immunoprotein, is involved in metastasis suppression.[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] IA4 IA4[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] InChI=1/C32H40BrN5O5.CH4O3S/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18;1-5(2,3)4/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39);1H3,(H,2,3,4)/t18-,23-,24+,25+,31-,32+;/m1./s1/f/h35H;2H InChIKey=NOJMTMIRQRDZMT-MXTIOCAADG KAI1 KAI1 Gene KAI1 Gene[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] KAI1[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] Parlodel Pravidel R2[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] SAR2 SAR2[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] ST6 ST6[accessedResource: C33H44BrN5O8S][accessDate: 05-04-2011] bromocriptine mesilate bromocriptine mesylate mercury dichloride A mercury coordination entity made up of linear triatomic molecules in which a mercury atom is bonded to two chlorines. Water-soluble, it is highly toxic. Once used in a wide variety of applications, including preserving wood and anatomical specimens, embalming and disinfecting, as an intensifier in photography, as a mordant for rabbit and beaver furs, and freeing gold from lead, its use has markedly declined as less toxic alternatives have been developed. A mercury coordination entity that has formula Cl2Hg. A white powder or crystalline solid made up of linear triatomic molecules in which a mercury atom is bonded to two chlorines. Water-soluble, it is highly toxic. Once used in a wide variety of applications, including preserving wood and anatomical specimens, embalming and disinfecting, as an intensifier in photography, as a mordant for rabbit and beaver furs, and freeing gold from lead, its use has markedly declined as less toxic alternatives have been developed. CHEBI:31823 Cl2Hg ClHgCl Cl[Hg]Cl HgCl2 InChI=1/2ClH.Hg/h2*1H;/q;;+2/p-2/f2Cl.Hg/h2*1h;/q2*-1;m InChIKey=LWJROJCJINYWOX-ZZJRNXLTCY James Malone Mercuric chloride Quecksilber(II)-chlorid Sublimat Sulema bichlorure de mercure chlorure mercurique corrosive mercury chloride corrosive sublimate dichloromercury dichlorure de mercure http://www.ebi.ac.uk/efo/EFO_0001671 hydrargyrum bichloratum mercuric bichloride mercury bichloride mercury perchloride mercury(2+) chloride mercury(II) chloride perchloride of mercury sublimate N-methyl-D-aspartic acid (R)-2-Methylamino-succinic acid 2-Methylamino-succinic acid An aspartic acid derivative having an N-methyl substituent and D-configuration. C5H9NO4 CHEBI:31882 CN[C@H](CC(O)=O)C(O)=O Ele Holloway InChI=1/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1/f/h7,9H InChIKey=HOKKHZGPKSLGJE-VCKMXKKJDP Methyl aspartic acid N-Methyl aspartic acid N-Methyl-D-aspartate N-Methylaspartate NMDA Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002731 oxaliplatin (SP-4-2)[(1R,2R)-cyclohexane-1,2-diamine-kappa(2)N,N'][ethanedioato(2-)-kappa(2)O(1),O(2)]platinum (SP-4-2-(1R-trans))-(1,2-cyclohexanediamine-N,N')(ethanedioato(2-)-O,O')platinum 16760 36760 61825-94-3 A platinum coordination entity that has formula C6H14N2.C2O4.Pt. C6H14N2.C2O4.Pt C8H12N2O4Pt C8H14N2O4Pt CP25 CP25[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Eloxatin Encoded by HOXC6 Gene (ANTP Family), 153- and 235-amino acid (27-kD) Homeobox C6 Protein isoforms are highly conserved sequence-specific DNA-binding homeobox transcription repressors that can cooperate with other HOX proteins and may contribute to the breast cell phenotype through co-operative interactions. As part of a developmental regulatory system that provides anterior-posterior positional identity to cells, HOXC6 may regulate the coordinated expression of multiple genes involved in morphogenesis and differentiation. (from LocusLink, Swiss-Prot, OMIM, and NCI) HHO.C8 HHO.C8[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] HOX3C HOX3C[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] HOXC6 HOXC6[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Homeobox Protein 3C Homeobox Protein 3C[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Homeobox Protein C6 Homeobox Protein C6[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Homeobox Protein C8 Homeobox Protein C8[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Homeobox Protein CP25 Homeobox Protein CP25[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Homeobox Protein HHO.C8 Homeobox Protein HHO.C8[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Homeobox Protein HOXC6 Homeobox Protein HOXC6[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Homeobox Protein Hox-3C Homeobox Protein Hox-3C[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Homeobox Protein Hox-C6 Homeobox Protein Hox-C6[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development. Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development.[accessedResource: C8H12N2O4Pt][accessDate: 05-04-2011] InChI=1/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2/t5-,6-;;/m1../s1/fC6H14N2.C2O4.Pt/q;-2;m InChIKey=ZROHGHOFXNOHSO-BEODOYRGDF [(1R,2R)-cyclohexane-1,2-diamine-k2N,N'][ethanedioato(2-)-k2O1,O2]platinum [H][N]1([H])[C@@H]2CCCC[C@H]2[N]([H])([H])[Pt]13OC(=O)C(=O)O3 oxalato(1,2-diaminocyclohexane)platinum(II) oxaliplatine oxaliplatino oxaliplatinum phenol red 143-74-8 22408 2408 3,3-bis(p-hydroxyphenyl)-3H-2,1-benzoxathiole 1,1-dioxide 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney. 4,4'-(1,1-dioxido-3H-2,1-benzoxathiole-3,3-diyl)diphenol 4,4'-(1,1-dioxido-3H-2,1-benzoxathiole-3,3-diyl)diphenol 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bisphenol S,S-dioxide C19H14O5S C19H14O5S Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst. Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst.[accessedResource: C19H14O5S][accessDate: 05-04-2011] InChI=1/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H InChIKey=BELBBZDIHDAJOR-UHFFFAOYAB Oc1ccc(cc1)C1(OS(=O)(=O)c2ccccc12)c1ccc(O)cc1 PSP Phenolsulfonphthalein Proto-Oncogene TRE-2 Proto-Oncogene TRE-2[accessedResource: C19H14O5S][accessDate: 05-04-2011] TRE-2 Gene TRE-2 Gene[accessedResource: C19H14O5S][accessDate: 05-04-2011] USP6 wt Allele USP6 wt Allele[accessedResource: C19H14O5S][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele[accessedResource: C19H14O5S][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 Gene Ubiquitin Specific Protease 6 Gene[accessedResource: C19H14O5S][accessDate: 05-04-2011] alpha-hydroxy-alpha,alpha-bis(p-hydroxyphenyl)-o-toluenesulfonic acid gamma-sultone potassium bromide 03/02/7758 A metal bromide salt with a K(+) counterion. BrK InChI=1/BrH.K/h1H;/q;+1/p-1/fBr.K/h1h;/q-1;m InChIKey=IOLCXVTUBQKXJR-RDJZLEBZCI KBr Kaliumbromid pirinixic acid ((4-Chloro-6-((2,3-dimethylphenyl)amino)-2-pyrimidinyl)thio)acetic acid (4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio)acetic acid ({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)acetic acid An aryl sulfide that has formula C14H14ClN3O2S. C14H14ClN3O2S CHEBI:32509 Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C InChI=1/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18)/f/h16,19H InChIKey=SZRPDCCEHVWOJX-YSFRZULJCA WY-14,643 http://www.ebi.ac.uk/efo/EFO_0001593 4-hydroxy-2-nonenal 4-Hydroxy-2,3-nonenal 4-Hydroxynonenal 4-hydroxynon-2-enal A hydroxyaldehyde that has formula C9H16O2. C9H16O2 CHEBI:32585 InChI=1/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3 InChIKey=JVJFIQYAHPMBBX-UHFFFAOYAI [H]C(=CC=O)C(O)CCCCC http://www.ebi.ac.uk/efo/EFO_0001472 potassium chloride A metal chloride salt with a K(+) counterion. An inorganic chloride salt that has formula ClK. CHEBI:32588 Ele Holloway InChI=1/ClH.K/h1H;/q;+1/p-1/fCl.K/h1h;/q-1;m InChIKey=WCUXLLCKKVVCTQ-UHVCZDMOCF James Malone Kaliumchlorid Kaon-Cl 10 Klor-con Klotrix Monopotassium chloride [Cl-].[K+] [KCl] http://www.ebi.ac.uk/efo/EFO_0002418 muriate of potash sylvite piperonylbutoxide (3,4-methylenedioxy-6-propylbenzyl) (butyl) diethylene glycol ether (butylcarbityl)(6-propylpiperonyl)ether 1166 2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether 21166 5-propyl-4-(2,5,8-trioxa-dodecyl)-1,3-benzodioxole 5-{[(2-{[2-(butyloxy)ethyl]oxy}ethyl)oxy]methyl}-6-propyl-1,3-benzodioxole 5-{[2-(2-butoxyethoxy)ethoxy]methyl}-6-propyl-1,3-benzodioxole 51-03-6 6-propylpiperonyl butyl diethylene glycol ether A benzodioxole that has formula C19H30O5. C19H30O5 C19H30O5 CCCCOCCOCCOCc1cc2OCOc2cc1CCC Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst. Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst.[accessedResource: C19H30O5][accessDate: 05-04-2011] InChI=1/C19H30O5/c1-3-5-7-20-8-9-21-10-11-22-14-17-13-19-18(23-15-24-19)12-16(17)6-4-2/h12-13H,3-11,14-15H2,1-2H3 InChIKey=FIPWRIJSWJWJAI-UHFFFAOYAD Proto-Oncogene TRE-2 Proto-Oncogene TRE-2[accessedResource: C19H30O5][accessDate: 05-04-2011] TRE-2 Gene TRE-2 Gene[accessedResource: C19H30O5][accessDate: 05-04-2011] USP6 wt Allele USP6 wt Allele[accessedResource: C19H30O5][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele[accessedResource: C19H30O5][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 Gene Ubiquitin Specific Protease 6 Gene[accessedResource: C19H30O5][accessDate: 05-04-2011] alpha-(2-(2-n-butoxyethoxy)-ethoxy)-4,5-methylenedioxy-2-propyltoluene alpha-[2-(2-butoxyethoxy)ethoxy]-4,5-(methylenedioxy)-2-propyltoluene butyl carbitol 6-propylpiperonyl ether piperonyl butoxide 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one 4-[methyl(nitroso)amino]-1-(pyridin-3-yl)butan-1-one 64091-91-4 A nitrosamine that has formula C10H13N3O2. C10H13N3O2 CN(CCCC(=O)c1cccnc1)N=O InChI=1/C10H13N3O2/c1-13(12-15)7-3-5-10(14)9-4-2-6-11-8-9/h2,4,6,8H,3,5,7H2,1H3 InChIKey=FLAQQSHRLBFIEZ-UHFFFAOYAR NNK (carcinogen) 1-naphthylacetic acid 1-naphthaleneacetic acid A naphthylacetic acid that has formula C12H10O2. C12H10O2 CHEBI:32918 Ele Holloway InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)/f/h13H InChIKey=PRPINYUDVPFIRX-NDKGDYFDCS James Malone NAA NAPHTHALEN-1-YL-ACETIC ACID OC(=O)Cc1cccc2ccccc12 alpha-NAA alpha-naphthaleneacetic acid http://www.ebi.ac.uk/efo/EFO_0002394 naphthalen-1-ylacetic acid naphthalene-1-acetic acid fluroanthene 206-44-0 24104 4A's Treatment Protocol 4As Treatment Protocol 4As Treatment Strategy A smoking cessation strategy recommended by the National Cancer Institute. The first 'A' is to ask patients about their smoking status at every visit and record this information. The second 'A' is to advise smokers to quit. The third 'A' is to assist patients' cessation attempts where possible by helping them to set a quit date, providing self-help materials, prescribing pharmacological treatment, and recommending counseling. The final 'A' is to arrange follow-up contact. (from Medscape) Acoustic Acoustic[accessedResource: C16H10][accessDate: 05-04-2011] An ortho- and peri-fused polycyclic arene that has formula C16H10. C16H10 C16H10 InChI=1/C16H10/c1-2-8-13-12(7-1)14-9-3-5-11-6-4-10-15(13)16(11)14/h1-10H InChIKey=GVEPBJHOBDJJJI-UHFFFAOYAL benzo[jk]fluorene c1ccc-2c(c1)-c1cccc3cccc-2c13 fluoranthene fluoranthene P-nitrotoluene 1-methyl-4-nitrobenzene 4-Nitrotoluene 4-Nitrotoluol 4-methylnitrobenzene 99-99-0 A member of the 4-nitrotoluenes that has formula C7H7NO2. C7H7NO2 Cc1ccc(cc1)N(=O)=O InChI=1/C7H7NO2/c1-6-2-4-7(5-3-6)8(9)10/h2-5H,1H3 InChIKey=ZPTVNYMJQHSSEA-UHFFFAOYAU PNT p-methylnitrobenzene para-Nitrotoluol O-nitrotoluene 1-methyl-2-nitrobenzene 2-Nitrotoluol 2-methyl-1-nitrobenzene 2-nitrotoluene 88-72-2 A nitrotoluene that has formula C7H7NO2. C7H7NO2 Cc1ccccc1N(=O)=O InChI=1/C7H7NO2/c1-6-4-2-3-5-7(6)8(9)10/h2-5H,1H3 InChIKey=PLAZTCDQAHEYBI-UHFFFAOYAA ONT o-Nitrotoluol o-methylnitrobenzene ortho-Nitrotoluol calcium chloride An inorganic chloride salt that has formula CaCl2. CaCl2 Calcium chloride anhydrous InChI=1/Ca.2ClH/h;2*1H/q+2;;/p-2/fCa.2Cl/h;2*1h/qm;2*-1 InChIKey=UXVMQQNJUSDDNG-HQDHFEKBCV [Cl-].[Cl-].[Ca++] calcium dichloride aluminium hydroxide 21645-51-2 36405 A member of the aluminium hydroxides that has formula H3AlO3. Al(OH)3 AlH3O3 Aluminiumhydroxid Aluminum hydroxide H3AlO3 H3AlO3 InChI=1/Al.3H2O/h;3*1H2/q+3;;;/p-3/fAl.3HO/h;3*1h/qm;3*-1 InChIKey=WNROFYMDJYEPJX-BLLOLPNJCE [H]O[Al](O[H])O[H] aluminium(3+) hydroxide aluminium(III) hydroxide aluminum trihydroxide trihydroxidoaluminium bisphenol A 2,2-Bis(4-Hydroxyphenyl)propane 2,2-Bis(p-hydroxyphenyl)propane 2,2-Di(4-hydroxyphenyl)propane 2,2-Di(4-phenylol)propane 4,4'-(1-Methylethylidene)bisphenol 4,4'-(propane-2,2-diyl)diphenol 4,4'-Bisphenol A 4,4'-Isopropylidenediphenol A bisphenol that has formula C15H16O2. C15H16O2 CC(C)(c1ccc(O)cc1)c1ccc(O)cc1 CHEBI:33216 InChI=1/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3 InChIKey=IISBACLAFKSPIT-UHFFFAOYAI http://www.ebi.ac.uk/efo/EFO_0001493 vitamin An organic substance that is distributed in foodstuffs, is distinct from the main organic components of food (protein, carbohydrate and fat) and is needed for the normal nutrition of the organism in question. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines. CHEBI:33229 James Malone http://www.ebi.ac.uk/efo/EFO_0001831 vitamina vitaminas vitamine vitamines vitamins vitaminum agrochemical An agrochemical is a substance that is used in agriculture or horticulture. CHEBI:33286 James Malone agrichemical agrichemicals agricultural chemicals agrochemicals http://www.ebi.ac.uk/efo/EFO_0001832 candesartan 10p11.1 10p11.1[accessedResource: C24H20N6O3][accessDate: 05-04-2011] 139481-59-7 2-(ethyloxy)-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid 2-ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benzimidazole-7-carboxylic acid 2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid 2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl}-1H-benzimidazole-7-carboxylic acid 22725 2725 A benzimidazolecarboxylic acid that has formula C24H20N6O3. A chromosome band present on 10p A chromosome band present on 10p[accessedResource: C24H20N6O3][accessDate: 05-04-2011] Blopress C24H20N6O3 C24H20N6O3 CCOc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 CV-11974 InChI=1/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)/f/h26,31H InChIKey=HTQMVQVXFRQIKW-NEQLIHFBCV adrenaline (+-)-epinephrine 2-(methylamino)-1-(3,4-dihydroxyphenyl)ethanol 329-65-7 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol A catecholamine that has formula C9H13NO3. C9H13NO3 CNCC(O)c1ccc(O)c(O)c1 InChI=1/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3 InChIKey=UCTWMZQNUQWSLP-UHFFFAOYAC dl-adrenaline epinephrine racemic racepinefrina racepinefrine racepinefrinum RNA A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed) (MSH) A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed) (MSH)[accessedResource: NIFSTD:sao1843715402][accessDate: 05-04-2011] High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins. James Malone Jie Zheng MO_594 NIFSTD:sao1843715402 RNA is a chemical compound which are naturally occurring polyribonucleotides. RNS Ribonukleinsaeure Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#RNA http://www.ebi.ac.uk/efo/EFO_0001454 pentosenucleic acids ribonucleic acid ribonucleic acids ribose nucleic acid yeast nucleic acid messenger RNA An RNA molecule that transfers the coding information for protein synthesis from the chromosomes to the ribosomes mRNA is formed from a DNA template by transcription. It may be a copy of a single gene or of several adjacent genes (polycistronic mRNA). On the ribosome, the sequence is converted into the programmed amino acid sequence through translation. mRNA template RNA carbamazepine 298-46-4 5-Carbamoyl-5H-dibenzo(b,f)azepine 5-Carbamyl-5H-dibenzo(b,f)azepine 5-carbamoyl-5H-dibenz[b,f]azepine 5H-Dibenz(b,f)azepine-5-carboxamide 5H-dibenzo[b,f]azepine-5-carboxamide An iminostilbene derivative with a carbamoyl group at the azepine nitrogen, used as an anticonvulsant. C15H12N2O Carbamazepen InChI=1/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)/f/h16H2 InChIKey=FFGPTBGBLSHEPO-ZHLVXTBQCX NC(=O)N1c2ccccc2C=Cc2ccccc12 carbamazepina carbamazepinum true carbaryl 1-Naphthalenol, methylcarbamate 1-Naphthyl N-methylcarbamate 20247 247 63-25-2 A carbamate ester that has formula C12H11NO2. A synthetic form of the Ras peptide containing a point mutation at position 12 (glycine to cysteine) with potential antineoplastic activity. Vaccination with this peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for this Ras mutation, resulting in decreased tumor growth. (NCI04) A synthetic form of the Ras peptide containing a point mutation at position 12 (glycine to cysteine) with potential antineoplastic activity. Vaccination with this peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for this Ras mutation, resulting in decreased tumor growth. (NCI04)[accessedResource: C12H11NO2][accessDate: 05-04-2011] C12H11NO2 C12H11NO2 CNC(=O)Oc1cccc2ccccc12 Carbaril InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)/f/h13H InChIKey=CVXBEEMKQHEXEN-NDKGDYFDCM N-Methyl-1-naphthyl carbamate N-Methyl-alpha-naphthylurethan Ras (sub 5-17) Peptide (C12) Ras (sub 5-17) Peptide (C12)[accessedResource: C12H11NO2][accessDate: 05-04-2011] Ras Peptide CYS Ras Peptide CYS[accessedResource: C12H11NO2][accessDate: 05-04-2011] Sevin alpha-Naphthyl N-methylcarbamate naphthalen-1-yl methylcarbamate naphthalen-1-yl methylcarbamate (9R,13R)-12-oxo-phytodienoic acid (9R,13R)-12-oxophytodienoic acid 12-oxophytodienoic acid 8-{(1R,5R)-4-oxo-5-[(2Z)-pent-2-en-1-yl]cyclopent-2-en-1-yl}octanoic acid C18H28O3 CC\\C=C/C[C@@H]1[C@H](CCCCCCCC(O)=O)C=CC1=O CHEBI:34005 Ele Holloway InChI=1/C18H28O3/c1-2-3-7-11-16-15(13-14-17(16)19)10-8-5-4-6-9-12-18(20)21/h3,7,13-16H,2,4-6,8-12H2,1H3,(H,20,21)/b7-3-/t15-,16-/m1/s1/f/h20H InChIKey=PMTMAFAPLCGXGK-VSUHVYTRDP James Malone OPDA The (9R,13R)-diastereomer of 12-oxophytodienoic acid. http://www.ebi.ac.uk/efo/EFO_0002482 16-ketoestradiol CHEBI:34165 Ele Holloway James Malone http://www.ebi.ac.uk/efo/EFO_0002485 chlorpyrifos An organochlorine acaricide that has formula C9H11Cl3NO3PS. C9H11Cl3NO3PS CCOP(=S)(OCC)Oc1nc(Cl)c(Cl)cc1Cl CHEBI:34631 Chlorpyrifos-ethyl Chlorpyriphos InChI=1/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3 InChIKey=SBPBAQFWLVIOKP-UHFFFAOYAG James Malone O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) phosphorothioate O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate Phosphorothioic acid, O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) ester Trichlorpyrphos http://www.ebi.ac.uk/efo/EFO_0001504 m-Chlorpyrifos o,o-Diethyl-o-(3,5,6-trichloro-2-pyridyl)phosphorothioate clofibric acid 2-(4-Chlorophenoxy)-2-methylpropionic acid 2-(4-chlorophenoxy)-2-methylpropanoic acid 2-(p-Chlorophenoxy)-2-methylpropionic acid 2-(p-Chlorophenoxy)isobutyric acid 4-CPIB A carboxylic acid that has formula C10H11ClO3. Acide (p-chlorophenoxy)-2 methyl-2 propionique C10H11ClO3 CC(C)(Oc1ccc(Cl)cc1)C(O)=O CHEBI:34648 CPIB Chlorfibrinic acid Chlorofibrinic acid Chlorophibrinic acid Clofibrate free acid Clofibrinsaeure Ele Holloway InChI=1/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)/f/h12H InChIKey=TXCGAZHTZHNUAI-XWKXFZRBCH James Malone PCIB PCPIB acide clofibrique acido clofibrico acidum clofibricum alpha-(4-chlorophenoxy)-alpha-methylpropionic acid alpha-(p-chlorophenoxy)isobutyric acid http://www.ebi.ac.uk/efo/EFO_0002405 dibutyl phthalate 1,2-Benzenedicarboxylic acid dibutyl ester 1781 21781 4A's Treatment Protocol 4As Treatment Protocol 4As Treatment Strategy 84-74-2 A smoking cessation strategy recommended by the National Cancer Institute. The first 'A' is to ask patients about their smoking status at every visit and record this information. The second 'A' is to advise smokers to quit. The third 'A' is to assist patients' cessation attempts where possible by helping them to set a quit date, providing self-help materials, prescribing pharmacological treatment, and recommending counseling. The final 'A' is to arrange follow-up contact. (from Medscape) Acoustic Acoustic[accessedResource: C16H22O4][accessDate: 05-04-2011] Benzene-o-dicarboxylic acid di-n-butyl ester Benzenedicarboxylic acid dibutyl ester Butyl phthalate C16H22O4 C16H22O4 CCCCOC(=O)c1ccccc1C(=O)OCCCC DBP Di-n-butyl phthalate Dibutyl o-phthalate InChI=1/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3 InChIKey=DOIRQSBPFJWKBE-UHFFFAOYAM Phthalic acid di-n-butyl ester Phthalic acid dibutyl ester The dibutyl ester of 1,2-benzenedicarboxylic acid. The dibutyl ester of benzene-1,2-dicarboxylic acid. dibutyl 1,2-benzenedicarboxylate dibutyl benzene-1,2-dicarboxylate dibutyl phthalate n-Butyl phthalate o-Benzenedicarboxylic acid dibutyl ester 3-isobutyl-1-methyl-7H-xanthine 1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione 1-methyl-3-(propan-2-yl)-3,7-dihydro-1H-purine-2,6-dione 1-methyl-3-isobutylxanthine 3-Isobutyl-1-methyxanthine 3-isobutyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione 3-isobutyl-1-methylxanthine A 3-isobutyl-1-methylxanthine that has formula C10H14N4O2. C10H14N4O2 CC(C)Cn1c2nc[nH]c2c(=O)n(C)c1=O CHEBI:34795 Ele Holloway IBMX InChI=1/C10H14N4O2/c1-6(2)4-14-8-7(11-5-12-8)9(15)13(3)10(14)16/h5-6H,4H2,1-3H3,(H,11,12)/f/h11H InChIKey=APIXJSLKIYYUKG-WXRBYKJCCL James Malone http://www.ebi.ac.uk/efo/EFO_0002396 methoprene (E,E)-1-Methylethyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate (E,E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid 1-methylethyl ester (E,E)-isopropyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate 12627 32627 40596-69-8 An isopropyl 11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate that has formula C19H34O3. C19H34O3 C19H34O3 COC(C)(C)CCCC(C)C\\C=C\\C(C)=C\\C(=O)OC(C)C Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst. Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst.[accessedResource: C19H34O3][accessDate: 05-04-2011] InChI=1/C19H34O3/c1-15(2)22-18(20)14-17(4)11-8-10-16(3)12-9-13-19(5,6)21-7/h8,11,14-16H,9-10,12-13H2,1-7H3/b11-8+,17-14+ InChIKey=NFGXHKASABOEEW-LDRANXPEBN Proto-Oncogene TRE-2 Proto-Oncogene TRE-2[accessedResource: C19H34O3][accessDate: 05-04-2011] TRE-2 Gene TRE-2 Gene[accessedResource: C19H34O3][accessDate: 05-04-2011] USP6 wt Allele USP6 wt Allele[accessedResource: C19H34O3][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele[accessedResource: C19H34O3][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 Gene Ubiquitin Specific Protease 6 Gene[accessedResource: C19H34O3][accessDate: 05-04-2011] ZR 515 isopropyl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate isopropyl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate isopropyl (EE)-(RS)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate propan-2-yl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate nocodazole (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-carbamic acid methyl ester A benzimidazole that has formula C14H11N3O3S. A thiophene that has formula C14H11N3O3S. C14H11N3O3S CHEBI:34892 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1cccs1 InChI=1/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)/f/h15,17H InChIKey=KYRVNWMVYQXFEU-KJQBJTEXCI N-(5-(2-thenoyl)-2-benzimidazolyl)carbamic acid methyl ester http://www.ebi.ac.uk/efo/EFO_0001580 methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate nocodazol nocodazolum paraquat 1,1'-Dimethyl-4,4'-bipyridinium 1,1'-dimethyl-4,4'-bipyridinium 1,1'-dimethyl-4,4'-bipyridyldiylium 1,1'-dimethyl-[4,4'-bipyridin]-1,1'-diium 14799 34799 4685-14-7 A synthetic form of the Ras peptide containing a point mutation at position 12 (glycine to cysteine) with potential antineoplastic activity. Vaccination with this peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for this Ras mutation, resulting in decreased tumor growth. (NCI04) A synthetic form of the Ras peptide containing a point mutation at position 12 (glycine to cysteine) with potential antineoplastic activity. Vaccination with this peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for this Ras mutation, resulting in decreased tumor growth. (NCI04)[accessedResource: C12H14N2][accessDate: 05-04-2011] C12H14N2 C12H14N2 C[n+]1ccc(cc1)-c1cc[n+](C)cc1 InChI=1/C12H14N2/c1-13-7-3-11(4-8-13)12-5-9-14(2)10-6-12/h3-10H,1-2H3/q+2 InChIKey=INFDPOAKFNIJBF-UHFFFAOYAI N,N'-dimethyl-4,4'-bipyridinium N,N'-dimethyl-4,4'-bipyridinium dication Ras (sub 5-17) Peptide (C12) Ras (sub 5-17) Peptide (C12)[accessedResource: C12H14N2][accessDate: 05-04-2011] Ras Peptide CYS Ras Peptide CYS[accessedResource: C12H14N2][accessDate: 05-04-2011] dimethyl viologen methyl viologen ion(2+) paraquat dication paraquat ion permethrin (3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate 22292 2292 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl ester 3-phenoxybenzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate 52645-53-1 C21 C21H20Cl2O3 C21H20Cl2O3 C21[accessedResource: C21H20Cl2O3][accessDate: 05-04-2011] CC1(C)C(C=C(Cl)Cl)C1C(=O)OCc1cccc(Oc2ccccc2)c1 DC42 DC42[accessedResource: C21H20Cl2O3][accessDate: 05-04-2011] FLJ12894 FLJ12894[accessedResource: C21H20Cl2O3][accessDate: 05-04-2011] Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia. Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia.[accessedResource: C21H20Cl2O3][accessDate: 05-04-2011] IRA1 IRA1[accessedResource: C21H20Cl2O3][accessDate: 05-04-2011] InChI=1/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3 InChIKey=RLLPVAHGXHCWKJ-UHFFFAOYAS TBL1XR1 wt Allele TBL1XR1 wt Allele[accessedResource: C21H20Cl2O3][accessDate: 05-04-2011] TBLR1 TBLR1[accessedResource: C21H20Cl2O3][accessDate: 05-04-2011] Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele[accessedResource: C21H20Cl2O3][accessDate: 05-04-2011] Transducin (Beta)-Like 1X-Linked Receptor 1 Gene Transducin (Beta)-Like 1X-Linked Receptor 1 Gene[accessedResource: C21H20Cl2O3][accessDate: 05-04-2011] [3-(phenyloxy)phenyl]methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate cefuroxime (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid 55268-75-2 A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain. C16H16N4O8S InChI=1/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1/f/h18,23H,17H2 InChIKey=JFPVXVDWJQMJEE-FLSWJVNSDK [H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1ccco1)C(O)=O zinc sulfate 20315 40315 7733-02-0 A metal sulfate compound having zinc(2+) as the counterion. InChI=1/H2O4S.Zn/c1-5(2,3)4;/h(H2,1,2,3,4);/q;+2/p-2/fO4S.Zn/q-2;m InChIKey=NWONKYPBYAMBJT-FXHKHQCPCZ O4SZn O4SZn ZnSO4 [Zn++].[O-]S([O-])(=O)=O zinc sulfate zinc sulfate (1:1) zinc sulfate anhydrous zinc sulphate zinc(2+) sulfate zinc(II) sulfate surfactant A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces. James Malone http://www.ebi.ac.uk/efo/EFO_0001620 surface active agent surfactants apratoxin A (2S,3S,5S,7S,10S,16S,19S,22S,25E,27S)-16-[(2S)-butan-2-yl]-7-tert-butyl-3-hydroxy-22-(4-methoxybenzyl)-2,5,17,19,20,25-hexamethyl-8-oxa-29-thia-14,17,20,23,30-pentaazatricyclo[25.2.1.0(10,14)]triaconta-1(30),25-diene-9,15,18,21,24-pentone 7'''.1,4-anhydro(N-{3-[2-(3,7-dihydroxy-5,8,8-trimethylnonan-2-yl)-4,5-dihydro-1,3-thiazol-4-yl]-2-methylpropenoyl}-O-methyl-L-tyrosyl-N-methyl-L-alanyl-N-methyl-L-isoleucyl-L-proline) An apratoxin that has formula C45H69N5O8S. C45H69N5O8S CHEBI:35212 InChI=1/C45H69N5O8S/c1-13-27(3)38-43(55)50-20-14-15-35(50)44(56)58-37(45(7,8)9)22-26(2)21-36(51)29(5)40-46-32(25-59-40)23-28(4)39(52)47-34(24-31-16-18-33(57-12)19-17-31)42(54)48(10)30(6)41(53)49(38)11/h16-19,23,26-27,29-30,32,34-38,51H,13-15,20-22,24-25H2,1-12H3,(H,47,52)/b28-23+/t26-,27-,29-,30-,32-,34-,35-,36-,37-,38-/m0/s1/f/h47H InChIKey=KXUJXPZXILTXDA-WUCPXUHADD N-((2E)-3-((4S)-4,5-dihydro-2-((1S,2S,4S,6S)-2,6-dihydroxy-1,4,7,7-tetramethyloctyl)-4-thiazolyl)-2-methyl-1-oxo-2-propenyl)-O-methyl-L-tyrosyl-N-methyl-L-alanyl-N-methyl-L-isoleucyl-L-proline (4-16)-lactone [H]N1[C@@H](Cc2ccc(OC)cc2)C(=O)N(C)[C@@H](C)C(=O)N(C)[C@@H]([C@@H](C)CC)C(=O)N2CCC[C@H]2C(=O)O[C@@H](C[C@@H](C)C[C@H](O)[C@H](C)C2=N[C@H](CS2)\\C=C(C)\\C1=O)C(C)(C)C http://www.ebi.ac.uk/efo/EFO_0001488 plant growth retardant CHEBI:35219 James Malone http://www.ebi.ac.uk/efo/EFO_0001833 plant growth inhibitor plant growth inhibitors plant growth retardants antimetabolite CHEBI:35221 James Malone Substance, structurally similar to a metabolite, which competes with it or replaces it, and so prevents or reduces its normal utilization. antimetabolites http://www.ebi.ac.uk/efo/EFO_0001834 inhibitor A substance that diminishes the rate of a chemical reaction. James Malone http://www.ebi.ac.uk/efo/EFO_0001898 inhibidor inhibiteur 1-benzofuran 2,3-benzofuran A benzofuran that has formula C8H6O. Benzofuran C8H6O CHEBI:35260 Ele Holloway InChI=1/C8H6O/c1-2-4-8-7(3-1)5-6-9-8/h1-6H InChIKey=IANQTJSKSUMEQM-UHFFFAOYAU James Malone benzo[b]furan c1ccc2occc2c1 coumaron coumarone cumarone http://www.ebi.ac.uk/efo/EFO_0002486 steroid Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from triterpenoids. a steroid steroids antinematodal drug A substance used in the treatment or control of nematode infestations. CHEBI:35444 James Malone antinematodal agent antinematodal drugs antinematodals http://www.ebi.ac.uk/efo/EFO_0001835 polychlorinated biphenyls 40591 PCBs chlorobiphenyl chlorobiphenyls 1-naphthyl isothiocyanate 1-Naphthylisothiocyanate 1-isothiocyanatonaphthalene ANIT CHEBI:35455 InChI=1/C11H7NS/c13-8-12-11-7-3-5-9-4-1-2-6-10(9)11/h1-7H InChIKey=JBDOSUUXMYMWQH-UHFFFAOYAA James Malone S=C=Nc1cccc2ccccc12 alpha-Naphthyl isothiocyanate http://www.ebi.ac.uk/efo/EFO_0001469 cadmium dichloride 10108-64-2 20226 226 A cadmium coordination entity that has formula CdCl2. Caddy CdCl2 CdCl2 Cl[Cd]Cl Dichlorocadmium InChI=1/Cd.2ClH/h;2*1H/q+2;;/p-2/fCd.2Cl/h;2*1h/qm;2*-1 InChIKey=YKYOUMDCQGMQQO-YJWIUFBSCR Kadmiumchlorid cadmium chloride cadmium dichloride cadmium(2+) chloride cadmium(II) chloride angiotensin-converting enzyme inhibito ACE inhibitor CHEBI:35457 James Malone angiotensin-converting enzyme inhibitor http://www.ebi.ac.uk/efo/EFO_0001836 anti-inflammatory drug A substance that reduces or suppresses inflammation. CHEBI:35472 James Malone anti-inflammatory agent anti-inflammatory drugs http://www.ebi.ac.uk/efo/EFO_0001837 non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. NSAID NSAIDs http://www.ebi.ac.uk/efo/EFO_0001582 non-steroidal anti-inflammatory agent non-steroidal anti-inflammatory drugs antipsychotic drug Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. NIFSTD:nlx_chem_20090603 Neuroleptikum Tomasz Adamusiak antipsychotic antipsychotic agents antipsychotic drugs antipsychotic[accessedResource: NIFSTD:nlx_chem_20090603][accessDate: 05-04-2011] antipsychotics antipsychotiques grosser Tranquilizer http://www.ebi.ac.uk/efo/EFO_0001486 major tranquilizers major tranquilizing agents neuroleptic neuroleptic agents neuroleptics neuroleptique neuroleptiques true antimanic drug Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders. CHEBI:35477 James Malone antimanic agent antimanic drugs antimanics http://www.ebi.ac.uk/efo/EFO_0001840 non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. CHEBI:35481 James Malone http://www.ebi.ac.uk/efo/EFO_0001841 antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. CHEBI:35493 James Malone http://www.ebi.ac.uk/efo/EFO_0001842 beta-adrenergic agonist An agent that selectively binds to and activates beta-adrenergic receptors. CHEBI:35522 James Malone beta-adrenergic agonists beta-adrenergic receptor agonist beta-adrenoceptor agonists http://www.ebi.ac.uk/efo/EFO_0001843 hypoglycemic drug A drug which lowers the blood glucose level. CHEBI:35526 James Malone antidiabetic http://www.ebi.ac.uk/efo/EFO_0001844 hypoglycemic agent cyclooxygenase inhibitor A compound or agent that combines with cyclooxygenases and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. CHEBI:35544 COX inhibitor James Malone cyclooxygenase inhibitors http://www.ebi.ac.uk/efo/EFO_0001845 cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. CHEBI:35554 James Malone cardiovascular agent cardiovascular drugs http://www.ebi.ac.uk/efo/EFO_0001846 pregnenolone 16alpha-carbonitrile 3beta-hydroxy-20-oxo-5-pregnene-16alpha-carbonitrile 3beta-hydroxy-20-oxopregn-5-ene-16alpha-carbonitrile A nitrile that has formula C22H31NO2. C22H31NO2 CHEBI:35591 InChI=1/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1 InChIKey=VSBHRRMYCDQLJF-ZDNYCOCVBP PCN [H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H]([C@@H](C[C@@]21[H])C#N)C(C)=O http://www.ebi.ac.uk/efo/EFO_0001596 pregnenolone carbonitrile antineoplastic drug A substance that inhibits or prevents the proliferation of neoplasms. CHEBI:35610 James Malone antineoplastic antineoplastic agent antineoplastic agents cytostatic http://www.ebi.ac.uk/efo/EFO_0001847 vasodilator agent A drug used to cause dilation of the blood vessels. http://www.ebi.ac.uk/efo/EFO_0001848 vasodilator vasodilator agents anticonvulsant A drug used to prevent seizures or reduce their severity. Antiepileptika Antiepileptikum Antikonvulsiva Antikonvulsivum CHEBI:35623 James Malone anticonvulsants anticonvulsive agent antiepileptic antiepileptics antiepileptique antiepileptiques http://www.ebi.ac.uk/efo/EFO_0001849 adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. CHEBI:35640 James Malone adrenergic uptake inhibitors http://www.ebi.ac.uk/efo/EFO_0001850 thiopurines CHEBI:35666 http://www.ebi.ac.uk/efo/EFO_0001568 http://www.ebi.ac.uk/efo/EFO_0001624 mercaptopurines sulfanylpurines thiopurine antilipemic drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). CHEBI:35679 James Malone antihyperlipemic antihyperlipidemic antilipemic antilipemic drugs http://www.ebi.ac.uk/efo/EFO_0001851 hypolipidemic agent cobalt dichloride CHEBI:35696 Chloride of cobalt in which the metal is in the +2 oxidation state. Cl2Co CoCl2 InChI=1/2ClH.Co/h2*1H;/q;;+2/p-2/f2Cl.Co/h2*1h;/q2*-1;m InChIKey=GVPFVAHMJGGAJG-ARVHXSLACZ Kobalt chlorid Kobalt(II)-chlorid Kobaltdichlorid [Cl-].[Cl-].[Co++] cobalt chloride cobalt muriate cobalt(2+) chloride cobalt(II) chloride cobaltous chloride cobaltous chloride anhydrous cobaltous dichloride dichlorocobalt http://www.ebi.ac.uk/efo/EFO_0001511 xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. CHEBI:35703 James Malone foreign"; bios "life http://www.ebi.ac.uk/efo/EFO_0001852 xenobiotic compounds xenobiotics immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. CHEBI:35705 James Malone http://www.ebi.ac.uk/efo/EFO_0001853 immunosuppressant immunosuppressive agents inmunosupresor sedative drug A drug used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. CHEBI:35717 James Malone http://www.ebi.ac.uk/efo/EFO_0001854 hypnotics sedatives sedatives and hypnotics antifungal drug A substance that destroys fungi by suppressing their ability to grow or reproduce. Antifungal drugs differ from industrial fungicides in that they defend against fungi present in human or animal tissues. CHEBI:35718 James Malone antifungal agent antifungal drugs http://www.ebi.ac.uk/efo/EFO_0001855 N-nitrosodimethylamine 1,1-Dimethyl-2-oxohydrazine A nitrosamine that has formula C2H6N2O. C2H6N2O CHEBI:35807 CN(C)N=O DMN Dimethylnitrosamine Dimethylnitrosoamine InChI=1/C2H6N2O/c1-4(2)3-5/h1-2H3 InChIKey=UMFJAHHVKNCGLG-UHFFFAOYAI N,N-Dimethylnitrosamine N-methyl-N-nitrosomethanamine http://www.ebi.ac.uk/efo/EFO_0001579 anticholesteremic drug A substance used to lower plasma cholesterol levels. CHEBI:35821 James Malone anticholesteremic anticholesteremic agent anticholesteremic drugs cholesterol inhibitor http://www.ebi.ac.uk/efo/EFO_0001856 hypocholesteremic agent antirheumatic drug A drug used to treat rheumatoid arthritis. CHEBI:35842 CHEBI:35842 James Malone anti-rheumatic drugs antirheumatic agent antirheumatic drugs http://www.ebi.ac.uk/efo/EFO_0001487 chlorhexidine 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) 55-56-1 A bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge. C22H30Cl2N10 Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1 InChI=1/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)/f/h25-34H InChIKey=GHXZTYHSJHQHIJ-FEWMDXPOCG N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)] N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide chloroquine 20446 40446 54-05-7 A quinoline alkaloid that has formula C18H26ClN3. Aralen Artrichin Bemaphate C18H26ClN3 C18H26ClN3 CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 Capquin Chlorochin EFABP EFABP[accessedResource: C18H26ClN3][accessDate: 05-04-2011] Epidermal Fatty Acid-Binding Protein Epidermal Fatty Acid-Binding Protein[accessedResource: C18H26ClN3][accessDate: 05-04-2011] Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI) Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI)[accessedResource: C18H26ClN3][accessDate: 05-04-2011] FABP5 FABP5[accessedResource: C18H26ClN3][accessDate: 05-04-2011] Fatty Acid Binding Protein 5 Fatty Acid Binding Protein 5[accessedResource: C18H26ClN3][accessDate: 05-04-2011] InChI=1/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)/f/h21H InChIKey=WHTVZRBIWZFKQO-PKSOQXRJCD N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine Nivaquine B PAFABP PAFABP[accessedResource: C18H26ClN3][accessDate: 05-04-2011] Resoquine Reumachlor Sanoquin chloroquinum cloroquina strontium chloride 10476-85-4 20616 40616 A strontium salt that has formula Cl2Sr. Cl2Sr Cl2Sr InChI=1/2ClH.Sr/h2*1H;/q;;+2/p-2/f2Cl.Sr/h2*1h;/q2*-1;m InChIKey=AHBGXTDRMVNFER-GSCHLNCOCE SrCl2 [Cl-].[Cl-].[Sr++] strontium dichloride strontium dichloride chlorpromazine 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine A phenothiazine that has formula C17H19ClN2S. A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety. Aminazine C17H19ClN2S CHEBI:3647 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 CPZ Chlorderazin Chloropromazine Chlorpromados Contomin InChI=1/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 InChIKey=ZPEIMTDSQAKGNT-UHFFFAOYAX James Malone Largactil N-(3-dimethylaminopropyl)-3-chlorophenothiazine Thorazine chlorpromazinum clorpromazina http://www.ebi.ac.uk/efo/EFO_0001503 chlorpropamide 1-(p-chlorobenzenesulfonyl)-3-propylurea 1-(p-chlorophenylsulfonyl)-3-propylurea 4-chloro-N-((propylamino)carbonyl)benzenesulfonamide 4-chloro-N-(propylcarbamoyl)benzenesulfonamide 94-20-2 C10H13ClN2O3S CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 InChI=1/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)/f/h12-13H InChIKey=RKWGIWYCVPQPMF-BAINRFMOCW N-(4-chlorophenylsulfonyl)-N'-propylurea Urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl and a hydrogen attached to the other nitrogen is substituted by propyl. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification. chlorpropamidum clorpropamida n-propyl-N'-(p-chlorobenzenesulfonyl)urea n-propyl-N'-p-chlorophenylsulfonylcarbamide sapphyrin A member of the sapphyrins that has formula C24H17N5. A sapphyrin that has formula C24H17N5. C24H17N5 CHEBI:36779 InChI=1/C24H17N5/c1-2-16-12-18-4-6-20(27-18)14-22-8-10-24(29-22)23-9-7-21(28-23)13-19-5-3-17(26-19)11-15(1)25-16/h1-14,25,28-29H/b15-11-,16-12-,17-11-,18-12-,19-13-,20-14-,21-13-,22-14-,24-23- InChIKey=COFLCBMDHTVQRA-DABHNVCVBQ c1cc2cc3ccc([nH]3)c3ccc(cc4ccc(cc5ccc(cc1n2)[nH]5)n4)[nH]3 http://www.ebi.ac.uk/efo/EFO_0001609 alpha-amanitin 1,8-anhydro-S(1),C(2.5)-cyclo[L-cysteinyl-L-asparaginyl-trans-4-hydroxy-L-prolyl-(R)-4,5-dihydroxy-L-isoleucyl-6-hydroxy-L-tryptophylglycyl-L-isoleucylglycine] (R)-S(1)-oxide 23109-05-9 A heterodetic cyclic peptide that has formula C39H54N10O14S. C39H54N10O14S InChI=1/C39H54N10O14S/c1-4-16(2)31-36(60)42-11-29(55)43-25-15-64(63)38-21(20-6-5-18(51)7-22(20)46-38)9-23(33(57)41-12-30(56)47-31)44-37(61)32(17(3)27(53)14-50)48-35(59)26-8-19(52)13-49(26)39(62)24(10-28(40)54)45-34(25)58/h5-7,16-17,19,23-27,31-32,46,50-53H,4,8-15H2,1-3H3,(H2,40,54)(H,41,57)(H,42,60)(H,43,55)(H,44,61)(H,45,58)(H,47,56)(H,48,59)/t16-,17-,19+,23-,24-,25-,26-,27-,31-,32-,64+/m0/s1/f/h41-45,47-48H,40H2 InChIKey=CIORWBWIBBPXCG-MKELGLIBDL [H][C@]12Cc3c([nH]c4cc(O)ccc34)[S@](=O)C[C@]([H])(NC(=O)CNC(=O)[C@@]([H])(NC(=O)CNC1=O)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1C[C@H](O)C[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)[C@@H](O)CO)C(=O)N2 alpha-Amatoxin alpha-amanitine clindamycin 18323-44-9 7(S)-Chloro-7-deoxylincomycin 7-CDL A S-glycosyl compound that has formula C18H33ClN2O5S. C18H33ClN2O5S CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC(C(C)Cl)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O Cleocin (TN) InChI=1/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9?,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1/f/h20H InChIKey=KDLRVYVGXIQJDK-JSWPLKRZDL Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside methyl 7-chloro-6,7,8-trideoxy-6-({[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl}amino)-1-thio-D-glycero-alpha-D-galacto-octopyranoside clofibrate 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester A propanoate ester that has formula C12H15ClO3. Atromid-S C12H15ClO3 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 CHEBI:3750 ELPI EPIB Ethyl 2-(p-chlorophenoxy)isobutyrate Ethyl chlorophenoxyisobutyrate Ethyl clofibrate InChI=1/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3 InChIKey=KNHUKKLJHYUCFP-UHFFFAOYAE Lipofacton Liprin alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester alpha-p-Chlorophenoxyisobutyryl ethyl ester clofibrato clofibratum ethyl 2-(4-chlorophenoxy)-2-methylpropanoate http://www.ebi.ac.uk/efo/EFO_0001508 phorbol 13-acetate 12-myristate (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl tetradecanoate 12-O-Tetradecanoylphorbol 13-acetate 12-Tetradecanoylphorbol 13-acetate A phorbol ester that has formula C36H56O8. C36H56O8 CHEBI:37537 Ele Holloway InChI=1/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30-,32-,34-,35-,36-/m1/s1 InChIKey=PHEDXBVPIONUQT-RGYGYFBIBK James Malone PMA [H][C@@]12C=C(CO)C[C@]3(O)C(=O)C(C)=C[C@@]3([H])[C@@]1(O)[C@H](C)[C@@H](OC(=O)CCCCCCCCCCCCC)[C@]1(OC(C)=O)[C@@]2([H])C1(C)C http://www.ebi.ac.uk/efo/EFO_0002493 phorbol 12-tetradecanoate 13-acetate tetradecanoylphorbol acetate sphingosine 1-phosphate (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate (2S,3R,4E)-2-amino-4-octadecene-1,3-diol 1-(dihydrogen phosphate) 26993-30-6 37166 A phosphosphingolipid that has formula C18H38NO5P. C18H38NO5P C18H38NO5P CCCCCCCCCCCCC\\C=C\\[C@@H](O)[C@@H](N)COP(O)(O)=O EFABP EFABP[accessedResource: C18H38NO5P][accessDate: 05-04-2011] Epidermal Fatty Acid-Binding Protein Epidermal Fatty Acid-Binding Protein[accessedResource: C18H38NO5P][accessDate: 05-04-2011] Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI) Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI)[accessedResource: C18H38NO5P][accessDate: 05-04-2011] FABP5 FABP5[accessedResource: C18H38NO5P][accessDate: 05-04-2011] Fatty Acid Binding Protein 5 Fatty Acid Binding Protein 5[accessedResource: C18H38NO5P][accessDate: 05-04-2011] InChI=1/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1/f/h21-22H InChIKey=DUYSYHSSBDVJSM-YIUDMRTDDG PAFABP PAFABP[accessedResource: C18H38NO5P][accessDate: 05-04-2011] Sphing-4-enine 1-phosphate clotrimazole 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole 1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole 1-(o-Chloro-alpha,alpha-diphenylbenzyl)imidazole 1-(o-Chlorotrityl)imidazole 1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole An imidazole that has formula C22H17ClN2. C22H17ClN2 CHEBI:3764 Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 InChI=1/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H InChIKey=VNFPBHJOKIVQEB-UHFFFAOYAO James Malone Lotrimin (TN) Mycelex (TN) http://www.ebi.ac.uk/efo/EFO_0001509 clozapine 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine A benzodiazepine that has formula C18H19ClN4. C18H19ClN4 CHEBI:3766 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 Clozapin InChI=1/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 InChIKey=QZUDBNBUXVUHMW-UHFFFAOYAL James Malone clozapina clozapinum http://www.ebi.ac.uk/efo/EFO_0001510 true protein kinase inhibitor An agent that inhibits protein kinases. CHEBI:37699 James Malone http://www.ebi.ac.uk/efo/EFO_0001858 protein kinase inhibitors protein kinase C inhibitor CHEBI:37700 James Malone http://www.ebi.ac.uk/efo/EFO_0001859 protein kinase C inhibitors cholinesterase inhibitor CHEBI:37733 James Malone http://www.ebi.ac.uk/efo/EFO_0001860 growth hormone A hormone that specifically regulates growth. Wachstumshormon growth hormones http://www.ebi.ac.uk/efo/EFO_0001548 plant growth hormone CHEBI:37848 James Malone http://www.ebi.ac.uk/efo/EFO_0001861 adrenergic antagonist An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. CHEBI:37887 James Malone adrenergic antagonists adrenergic blockaders adrenergic blocker adrenergic blockers adrenergic receptor blockaders adrenoceptor antagonists http://www.ebi.ac.uk/efo/EFO_0001862 obsolete_alpha-adrenergic antagonist duplicates imported class 2.23 phenothiazine antipsychotic drug CHEBI:37930 James Malone http://www.ebi.ac.uk/efo/EFO_0001864 phenothiazine antipsychotic drugs phenothiazine antipsychotics phenothiazine neuroleptics histamine antagonist CHEBI:37956 Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. James Malone antihistamine antihistamines antihistaminico antihistaminics histamine receptor blocker histamine receptor blockers http://www.ebi.ac.uk/efo/EFO_0001865 methyltrienolone (17beta)-17-hydroxy-17-methylestra-4,9,11-trien-3-one 14162 17-methyloestra-4,9,11-trien-3-one,17beta-ol 17alpha-Methyltrienolone 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one 34162 965-93-5 A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors. C19H24O2 C19H24O2 Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst. Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst.[accessedResource: C19H24O2][accessDate: 05-04-2011] InChI=1/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1 InChIKey=CCCIJQPRIXGQOE-XWSJACJDBS Proto-Oncogene TRE-2 Proto-Oncogene TRE-2[accessedResource: C19H24O2][accessDate: 05-04-2011] R1881 R1881 (synthetic androgen) TRE-2 Gene TRE-2 Gene[accessedResource: C19H24O2][accessDate: 05-04-2011] USP6 wt Allele USP6 wt Allele[accessedResource: C19H24O2][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele[accessedResource: C19H24O2][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 Gene Ubiquitin Specific Protease 6 Gene[accessedResource: C19H24O2][accessDate: 05-04-2011] [H][C@@]12CCC3=CC(=O)CCC3=C1C=C[C@@]1(C)[C@@]2([H])CC[C@]1(C)O metribolona metribolone metribolonum uniconazole-P (1E)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol (E)-(+-)-beta-((4-chlorophenyl)methylene)-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol A secondary alcohol that has formula C15H18ClN3O. A triazole that has formula C15H18ClN3O. C15H18ClN3O CC(C)(C)C(O)C(\\n1cncn1)=C/c1ccc(Cl)cc1 CHEBI:38000 InChI=1/C15H18ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-10,14,20H,1-3H3/b13-8+ InChIKey=YNWVFADWVLCOPU-MDWZMJQEBY http://www.ebi.ac.uk/efo/EFO_0001633 uniconazole cardiotonic drug A drug that has a strengthening effect on the heart or that can increase cardiac output. CHEBI:38147 James Malone cardiotonic drugs http://www.ebi.ac.uk/efo/EFO_0001866 potassium bromate 02/01/7758 A bromate salt that has formula BrKO3. BrKO3 BrO3.K Bromic acid, potassium salt InChI=1/BrHO3.K/c2-1(3)4;/h(H,2,3,4);/q;+1/p-1/fBrO3.K/q-1;m InChIKey=OCATYIAKPYKMPG-RERGACQYCO [K+].[O-]Br(=O)=O potassium trioxidobromate(1-) potassium trioxobromate calcium channel blocker CHEBI:38215 James Malone One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. calcium channel blockers http://www.ebi.ac.uk/efo/EFO_0001867 acetylcholinesterase inhibitor AChEI Any substance that inhibits the enzyme acetylcholinesterase from breaking down acetylcholine into choline and acetic acid. CHEBI:38462 James Malone acetylcholine esterase inhibitor acetylcholinesterase inhibitors http://www.ebi.ac.uk/efo/EFO_0001868 acetonitrile 20009 75-05-8 9 A nitrile that has formula C2H3N. C2 Mouse C2 Mouse[accessedResource: C2H3N][accessDate: 05-04-2011] C2H3N C2H3N C2[accessedResource: C2H3N][accessDate: 05-04-2011] CC#N CH3-C#N InChI=1/C2H3N/c1-2-3/h1H3 InChIKey=WEVYAHXRMPXWCK-UHFFFAOYAJ MeCN NCMe acetonitrile cyanomethane ethanenitrile methyl cyanide mitochondrial NADH:ubiquinone reductase inhibitor CHEBI:38498 James Malone http://www.ebi.ac.uk/efo/EFO_0001869 mitochondrial NADH dehydrogenase inhibitor mitochondrial complex I inhibitor mitochondrial complex I inhibitors fenazaquin 11-Eicosenoic Acid 11-Eicosenoic Acid[accessedResource: C20H22N2O][accessDate: 05-04-2011] 120928-09-8 20476 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline 4-tert-butylphenethylquinazolin-4-yl ether 40476 A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration. A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration.[accessedResource: C20H22N2O][accessDate: 05-04-2011] A quinazoline that has formula C20H22N2O. C20:1 n-9 cis C20:1 n-9 cis[accessedResource: C20H22N2O][accessDate: 05-04-2011] C20H22N2O C20H22N2O CC(C)(C)c1ccc(CCOc2ncnc3ccccc23)cc1 Cis-icos-11-enoic Cis-icos-11-enoic[accessedResource: C20H22N2O][accessDate: 05-04-2011] Fatty Acid 20:1 n-9 Fatty Acid 20:1 n-9[accessedResource: C20H22N2O][accessDate: 05-04-2011] Gondoic Acid Gondoic Acid[accessedResource: C20H22N2O][accessDate: 05-04-2011] InChI=1/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3 InChIKey=DMYHGDXADUDKCQ-UHFFFAOYAT tyrosine kinase inhibitor CHEBI:38637 James Malone http://www.ebi.ac.uk/efo/EFO_0001870 protein tyrosine kinase inhibitor tyrosine kinase inhibitors phosmet 24261 4261 732-11-6 A radiotracer consisting of choline labeled with the positron-emitting isotope carbon C 11 with potential imaging use. Upon administration, C-11 choline incorporates into tumor cells through an active, carrier-mediated transport mechanism for choline and then is phosphorylated intracellularly by choline kinase, an enzyme frequently upregulated in human tumors, yielding phosphoryl C-11 choline. In turn, phosphoryl C-11 choline is integrated into phospholipids in the cell membrane as part of phosphatidylcholine. As the proliferation of cancer cells is much higher than normal cells, tumor cells exhibit an increased rate of C-11 choline uptake and incorporation, allowing tunor imaging with positron emission tomography (PET). A radiotracer consisting of choline labeled with the positron-emitting isotope carbon C 11 with potential imaging use. Upon administration, C-11 choline incorporates into tumor cells through an active, carrier-mediated transport mechanism for choline and then is phosphorylated intracellularly by choline kinase, an enzyme frequently upregulated in human tumors, yielding phosphoryl C-11 choline. In turn, phosphoryl C-11 choline is integrated into phospholipids in the cell membrane as part of phosphatidylcholine. As the proliferation of cancer cells is much higher than normal cells, tumor cells exhibit an increased rate of C-11 choline uptake and incorporation, allowing tunor imaging with positron emission tomography (PET).[accessedResource: C11H12NO4PS2][accessDate: 05-04-2011] An organothiophosphate insecticide that has formula C11H12NO4PS2. C-11 Choline C-11 Choline[accessedResource: C11H12NO4PS2][accessDate: 05-04-2011] C11 Choline C11 Choline[accessedResource: C11H12NO4PS2][accessDate: 05-04-2011] C11H12NO4PS2 C11H12NO4PS2 COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O Carbon C 11 Choline Carbon C 11 Choline[accessedResource: C11H12NO4PS2][accessDate: 05-04-2011] Carbon C11 Choline Decemthion Fosmet InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3 InChIKey=LMNZTLDVJIUSHT-UHFFFAOYAV O,O-Dimethyl S-(phthalimidomethyl) dithiophosphate O,O-Dimethyl S-phthalimidomethyl phosphorodithioate O,O-Dimethyl phthalimidomethyl phosphorodithioate PMP S-((1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl)phosphorodithioic acid O,O-dimethyl ester S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl phosphorodithioate non ionic surfactant A surfactant with an uncharged hydrophilic headgroup. James Malone http://www.ebi.ac.uk/efo/EFO_0001581 nonionic surfactant nonionic surfactants inhalation anaesthetic CHEBI:38870 Inhalationsanaesthetika Inhalationsanaesthetikum Inhalationsnarkotika Inhalationsnarkotikum James Malone anesthetic gases http://www.ebi.ac.uk/efo/EFO_0001871 inhalation anesthetics intravenous anaesthetic CHEBI:38877 James Malone http://www.ebi.ac.uk/efo/EFO_0001872 i.v.-Anaesthetika i.v.-Anaesthetikum intravenous anesthetics adrenocorticotropic hormone 40808 9002-60-2 A polypeptide hormone produced and secreted by the pituitary gland comprising 39 amino acid residues coupled in a linear sequence. The N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). It is used in the treatment of certain neurological disorders such as infantile spasms and multiple sclerosis, and diagnostically to investigate adrenocortical insufficiency. ACTH C207H308N56O58S CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O Corticotropin InChI=1/C207H308N56O58S/c1-108(2)89-140(186(302)240-135(69-74-163(279)280)182(298)254-149(204(320)321)94-117-43-20-15-21-44-117)250-193(309)152-54-35-86-262(152)202(318)147(92-116-41-18-14-19-42-116)252-171(287)114(11)230-175(291)132(66-71-160(273)274)234-170(286)113(10)231-191(307)150(105-265)255-183(299)136(70-75-164(281)282)241-190(306)146(98-165(283)284)249-180(296)133(67-72-161(275)276)235-169(285)112(9)229-157(270)101-225-174(290)145(97-156(213)269)251-194(310)153-55-36-87-263(153)203(319)148(93-119-60-64-123(268)65-61-119)253-199(315)167(110(5)6)257-185(301)129(49-26-30-79-210)243-198(314)168(111(7)8)259-196(312)155-57-38-85-261(155)201(317)139(53-34-83-223-207(218)219)244-178(294)130(51-32-81-221-205(214)215)237-177(293)128(48-25-29-78-209)236-176(292)127(47-24-28-77-208)232-158(271)103-227-197(313)166(109(3)4)258-195(311)154-56-37-84-260(154)200(316)138(50-27-31-80-211)233-159(272)102-226-173(289)143(95-120-99-224-126-46-23-22-45-124(120)126)247-179(295)131(52-33-82-222-206(216)217)238-187(303)142(90-115-39-16-13-17-40-115)246-189(305)144(96-121-100-220-107-228-121)248-181(297)134(68-73-162(277)278)239-184(300)137(76-88-322-12)242-192(308)151(106-266)256-188(304)141(245-172(288)125(212)104-264)91-118-58-62-122(267)63-59-118/h13-23,39-46,58-65,99-100,107-114,125,127-155,166-168,224,264-268H,24-38,47-57,66-98,101-106,208-212H2,1-12H3,(H2,213,269)(H,220,228)(H,225,290)(H,226,289)(H,227,313)(H,229,270)(H,230,291)(H,231,307)(H,232,271)(H,233,272)(H,234,286)(H,235,285)(H,236,292)(H,237,293)(H,238,303)(H,239,300)(H,240,302)(H,241,306)(H,242,308)(H,243,314)(H,244,294)(H,245,288)(H,246,305)(H,247,295)(H,248,297)(H,249,296)(H,250,309)(H,251,310)(H,252,287)(H,253,315)(H,254,298)(H,255,299)(H,256,304)(H,257,301)(H,258,311)(H,259,312)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,320,321)(H4,214,215,221)(H4,216,217,222)(H4,218,219,223)/t112-,113-,114-,125-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,166-,167-,168-/m0/s1/f/h214,216,218,221-223,225-259,273,275,277,279,281,283,320H,213,215,217,219H2 InChIKey=IDLFZVILOHSSID-KPRWYZAZDY L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-alpha-aspartylglycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine SYSMEHFRWGKPVGKKRRPVKVYPDGAEDQLAEAFPLEF adrenocorticotropin corticotrofina corticotrophine corticotrophinum cortrophin sunitinib 21134 41134 557795-19-4 A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration. A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration.[accessedResource: C22H27FN4O2][accessDate: 05-04-2011] A pyrrole that has formula C22H27FN4O2. Brassidic Acid Brassidic Acid[accessedResource: C22H27FN4O2][accessDate: 05-04-2011] C22:1, n-9 trans C22:1, n-9 trans[accessedResource: C22H27FN4O2][accessDate: 05-04-2011] C22H27FN4O2 C22H27FN4O2 CCN(CC)CCNC(=O)c1c(C)[nH]c(\\C=C2/C(=O)Nc3ccc(F)cc23)c1C Fatty Acid 22:1 n-9 trans Fatty Acid 22:1 n-9 trans[accessedResource: C22H27FN4O2][accessDate: 05-04-2011] Fatty Acid trans 22:1 n-9 Fatty Acid trans 22:1 n-9[accessedResource: C22H27FN4O2][accessDate: 05-04-2011] InChI=1/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-/f/h24,26H InChIKey=WINHZLLDWRZWRT-IUQVRHKZDC N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-3H-pyrrole-3-carboxamide SU-11248 Sutent Trans docos-13-enoic Acid Trans docos-13-enoic Acid[accessedResource: C22H27FN4O2][accessDate: 05-04-2011] sunitinibum pyrethroid ester insecticide CHEBI:39116 James Malone http://www.ebi.ac.uk/efo/EFO_0001873 pyrethroid ester insecticides abamectin (2aE,4E,8E)-(5'S,6S,6'R,7S,11R,13S,15S,17aR,20R,20aR,20bS)-6'-((S)-sec-Butyl)-5',6,6',7,10,11,14,15,17a,20,20a,20b-dodecahydro-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxospiro(11,15-methano-2H,13H,17H-furo(4,3,2-pq)(2,6)benzodioxacyclooctadecin-13,2'-(2H)pyran)-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside 10q23.33 10q23.33[accessedResource: C48H72O14][accessDate: 05-04-2011] 23892 3892 71751-41-2 A chromosome band present on 10q A chromosome band present on 10q[accessedResource: C48H72O14][accessDate: 05-04-2011] Agri-Mek Avid C48H72O14 MK 936 Mixture of 80% avermectin B1a and 20% avermectin B1b. Zephyr avermectin B1 dinitrophenol C6H4N2O5 CHEBI:39352 http://www.ebi.ac.uk/efo/EFO_0001524 lufenuron "Blue Bone" Formation 1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea 103055-07-8 14357 34357 A benzoylurea insecticide that has formula C17H8Cl2F8N2O3. ABL1 ABL1 Gene ABL1 Gene[accessedResource: C17H8Cl2F8N2O3][accessDate: 05-04-2011] ABL1[accessedResource: C17H8Cl2F8N2O3][accessDate: 05-04-2011] C17H8Cl2F8N2O3 C17H8Cl2F8N2O3 FC(C(F)(F)F)C(F)(F)Oc1cc(Cl)c(NC(=O)NC(=O)c2c(F)cccc2F)cc1Cl Fluphenacur InChI=1/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)/f/h28-29H InChIKey=PWPJGUXAGUPAHP-LKHHGCNMCM N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide This gene is involved in cell adhesion, differentiation, division and stress response. This gene is involved in cell adhesion, differentiation, division and stress response.[accessedResource: C17H8Cl2F8N2O3][accessDate: 05-04-2011] v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene v-Abl Abelson Murine Leukemia Viral Oncogene Homolog 1 Gene[accessedResource: C17H8Cl2F8N2O3][accessDate: 05-04-2011] atorvastatin (3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid (3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-4-phenyl-2-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid (R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid 134523-00-5 29868 4F9 4F9[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] 7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID 9868 A dihydroxy monocarboxylic acid that has formula C33H35FN2O5. Atorlip C33 C33H35FN2O5 C33H35FN2O5 C33[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O CD82 CD82 Antigen wt Allele CD82 Antigen wt Allele[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] CD82 wt Allele CD82 wt Allele[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] CD82[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] GR15 GR15[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] Human CD82 wild-type allele is located in the vicinity of 11p11.2 and is approximately 54 kb in length. This allele, which encodes CD82 antigen Immunoprotein, is involved in metastasis suppression. Human CD82 wild-type allele is located in the vicinity of 11p11.2 and is approximately 54 kb in length. This allele, which encodes CD82 antigen Immunoprotein, is involved in metastasis suppression.[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] IA4 IA4[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] InChI=1/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1/f/h35,39H InChIKey=XUKUURHRXDUEBC-WPPSOWBEDM KAI1 KAI1 Gene KAI1 Gene[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] KAI1[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] SAR2 SAR2[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] ST6 ST6[accessedResource: C33H35FN2O5][accessDate: 05-04-2011] atorvastatina atorvastatine atorvastatinium curcumin (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione (1E,6E)-1,7-bis[4-hydroxy-3-(methyloxy)phenyl]hepta-1,6-diene-3,5-dione 1421 31077 458-37-7 A polyphenol that has formula C21H20O6. C21 C21H20O6 C21H20O6 C21[accessedResource: C21H20O6][accessDate: 05-04-2011] COc1cc(ccc1O)\\C=C\\C(=O)CC(=O)\\C=C\\c1ccc(O)c(OC)c1 DC42 DC42[accessedResource: C21H20O6][accessDate: 05-04-2011] Diferuloylmethane FLJ12894 FLJ12894[accessedResource: C21H20O6][accessDate: 05-04-2011] Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia. Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia.[accessedResource: C21H20O6][accessDate: 05-04-2011] IRA1 IRA1[accessedResource: C21H20O6][accessDate: 05-04-2011] InChI=1/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+ InChIKey=VFLDPWHFBUODDF-FCXRPNKRBF Kacha haldi Natural yellow 3 TBL1XR1 wt Allele TBL1XR1 wt Allele[accessedResource: C21H20O6][accessDate: 05-04-2011] TBLR1 TBLR1[accessedResource: C21H20O6][accessDate: 05-04-2011] Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele[accessedResource: C21H20O6][accessDate: 05-04-2011] Transducin (Beta)-Like 1X-Linked Receptor 1 Gene Transducin (Beta)-Like 1X-Linked Receptor 1 Gene[accessedResource: C21H20O6][accessDate: 05-04-2011] Turmeric yellow valproic acid 2-PROPYL-PENTANOIC ACID 2-n-propyl-n-valeric acid 2-propylpentanoic acid 2-propylvaleric acid 4-heptanecarboxylic acid A branched, short-chain, saturated fatty acid comprising a propyl substituent on a pentanoic acid stem. A branched, short-chain, saturated fatty acid comprising a propyl substituent on a pentanoic acid stem. An anti-epilectic and anti-carcinogenic drug with toxic and teratogenic properties, which dissolves to valproate in the gut. A monocarboxylic acid that has formula C8H16O2. C8H16O2 CCCC(CCC)C(O)=O CHEBI:39867 DPA Depakene Di-n-propylessigsaeure InChI=1/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)/f/h9H InChIKey=NIJJYAXOARWZEE-BGGKNDAXCP James Malone VPA Valproinsaeure acide valproique acido valproico acidum valproicum di-n-propylacetic acid dipropylacetic acid http://www.ebi.ac.uk/efo/EFO_0001634 n-DPA cyclophosphamide (RS)-Cyclophosphamide 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide 20364 364 50-18-0 A cyclic phosphorodiamide-based nitrogen mustard. Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester C7 C7H15Cl2N2O2P C7H15Cl2N2O2P C7[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] CRG-2 CRG-2[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] CXCL10 wt Allele CXCL10 wt Allele[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] Chemokine (C-X-C Motif) Ligand 10 wt Allele Chemokine (C-X-C Motif) Ligand 10 wt Allele[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] ClCCN(CCCl)P1(=O)NCCCO1 Cyclophosphamide anhydrous Human CXCL10 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine B10 protein, plays a role in both immune cell migration and in the modulation of adhesion molecule expression. Human CXCL10 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine B10 protein, plays a role in both immune cell migration and in the modulation of adhesion molecule expression.[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] IFI10 IFI10[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] INP10 INP10[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] IP-10 IP-10[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] InChI=1/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)/f/h10H InChIKey=CMSMOCZEIVJLDB-KZFATGLACB MOB-1 MOB-1[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide SCYB10 SCYB10[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] gIP-10 gIP-10[accessedResource: C7H15Cl2N2O2P][accessDate: 05-04-2011] cyclosporin A (R-[R*,R*-(E)])-Cyclic(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alpha-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl) 1,11-cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(E)-(2S,3R,4R)-2-amino-3-hydroxy-N,4-dimethyloct-6-enoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine] 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. A homodetic cyclic peptide that has formula C62H111N11O12. Antibiotic S 7481F1 C62H111N11O12 CC[C@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\\C=C\\C)N(C)C(=O)[C@@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C CHEBI:4031 Ciclosporin Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-((3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl)-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methylleucyl) Cyclosporine Gengraf InChI=1/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42+,43-,44+,45-,46+,47+,49+,50-,51+,52-/m1/s1/f/h63-66H InChIKey=PMATZTZNYRCHOR-MDVWSCMIDT James Malone Neoral Sandimmune ciclosporina ciclosporine ciclosporinum http://www.ebi.ac.uk/efo/EFO_0001506 cyfluthrin (R,S)-alpha-Cyano-4-fluoro-3-phenoxybenzyl-(1R,S)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate C22H18Cl2FNO3 CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c1ccc(F)c(Oc2ccccc2)c1 CHEBI:4034 InChI=1/C22H18Cl2FNO3/c1-22(2)15(11-19(23)24)20(22)21(27)29-18(12-26)13-8-9-16(25)17(10-13)28-14-6-4-3-5-7-14/h3-11,15,18,20H,1-2H3 InChIKey=QQODLKZGRKWIFG-UHFFFAOYAM James Malone cyano(4-fluoro-3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate http://www.ebi.ac.uk/efo/EFO_0001515 celecoxib 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide A pyrazole that has formula C17H14F3N3O2S. C17H14F3N3O2S CHEBI:41423 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Celebrex (TN) InChI=1/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)/f/h21H2 InChIKey=RZEKVGVHFLEQIL-QVUQFMIFCW James Malone http://www.ebi.ac.uk/efo/EFO_0001501 p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide tamoxifen (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine A tertiary amine that has formula C26H29NO. Apo-Tamox C26H29NO CC\\C(c1ccccc1)=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1 CHEBI:41774 Crisafeno Diemon InChI=1/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25- InChIKey=NKANXQFJJICGDU-QPLCGJKRBF James Malone http://www.ebi.ac.uk/efo/EFO_0001621 tamoxifene tamoxifeno tamoxifenum trans-Tamoxifen dexamethasone 1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone 16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 9alpha-Fluoro-16alpha-methylprednisolone A fluorinated steroid that has formula C22H29FO5. C22H29FO5 CHEBI:41879 Decadron InChI=1/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 InChIKey=UREBDLICKHMUKA-CXSFZGCWBM James Malone [H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C dexametasona dexamethasonum http://www.ebi.ac.uk/efo/EFO_0001519 diethylstilbestrol (E)-3,4-bis(4-hydroxyphenyl)-3-hexene (E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol 4,4'-dihydroxy-alpha,beta-diethylstilbene An estrogen that has formula C18H20O2. C18H20O2 CC\\C(c1ccc(O)cc1)=C(\\CC)c1ccc(O)cc1 CHEBI:41922 Distilbene InChI=1/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+ InChIKey=RGLYKWWBQGJZGM-ISLYRVAYBW James Malone alpha,alpha'-diethyl-(E)-4,4'-stilbenediol diethylstilbestrolum dietilestilbestrol http://www.ebi.ac.uk/efo/EFO_0001522 trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol trans-Diethylstilbesterol trans-Diethylstilbestrol trans-Diethylstilboesterol 2,4-dinitrophenol 1-hydroxy-2,4-dinitrobenzene 2,4-DNP 2,4-dinitrophenol 20523 51-28-5 523 A dinitrophenol having the nitro groups at the 2- and 4-positions. Any of the six isomers consisting of phenol where two hydrogen atoms are substituted by nitro groups. C6 Vertebra C6 Vertebra[accessedResource: C6H4N2O5][accessDate: 05-04-2011] C6H4N2O5 C6H4N2O5 InChI=1/C6H4N2O5/c9-6-2-1-4(7(10)11)3-5(6)8(12)13/h1-3,9H InChIKey=UFBJCMHMOXMLKC-UHFFFAOYAV Oc1ccc(cc1N(=O)=O)N(=O)=O The sixth of the seven cervical vertebrae. The sixth of the seven cervical vertebrae.[accessedResource: C6H4N2O5][accessDate: 05-04-2011] alpha-dinitrophenol dinitrophenol; DNP forskolin (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate 7beta-acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxylabd-14-en-11-one A labdane diterpenoid that has formula C22H34O7. C22H34O7 CHEBI:42471 InChI=1/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1 InChIKey=OHCQJHSOBUTRHG-KGGHGJDLBB [H][C@@]12[C@H](O)[C@H](OC(C)=O)[C@@]3(C)O[C@](C)(CC(=O)[C@]3(O)[C@@]1(C)[C@@H](O)CCC2(C)C)C=C colforsin colforsina colforsine colforsinum http://www.ebi.ac.uk/efo/EFO_0001539 flavone 2-phenyl-4H-1-benzopyran-4-one 2-phenyl-4H-benzopyran-4-one 2-phenyl-4H-chromen-4-one 2-phenyl-gamma-benzopyrone 2-phenylchromone A flavone that has formula C15H10O2. A member of the flavones that has formula C15H10O2. C15H10O2 CHEBI:42491 Flavon InChI=1/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H InChIKey=VHBFFQKBGNRLFZ-UHFFFAOYAG O=c1cc(oc2ccccc12)-c1ccccc1 http://www.ebi.ac.uk/efo/EFO_0001535 fisetin 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one 3,3',4',7-Tetrahydroxyflavone 5-Desoxyquercetin 7,3',4'-Trihydroxyflavonol A tetrahydroxyflavone that has formula C15H10O6. C15H10O6 CHEBI:42567 InChI=1/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H InChIKey=XHEFDIBZLJXQHF-UHFFFAOYAQ Oc1ccc2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O http://www.ebi.ac.uk/efo/EFO_0001534 flufenamic acid 2-[3-(trifluoromethyl)anilino]benzoic acid 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid 3'-trifluoromethyldiphenylamine-2-carboxylic acid Achless An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. Ansatin Arlef C14H10F3NO2 CHEBI:42638 FFA Flufenaminsaeure Fullsafe InChI=1/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)/f/h19H InChIKey=LPEPZBJOKDYZAD-LILDFLRNCJ James Malone Meralen N-(3-trifluoromethylphenyl)anthranilic acid N-(alpha,alpha,alpha-trifluoro-m-tolyl)anthranilic acid OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F Paraflu Parlef Ristogen Sastridex Surika Tecramine acide flufenamique acido flufenamico acidum flufenamicum fluphenamic acid http://www.ebi.ac.uk/efo/EFO_0001537 desferrioxamine B An acyclic desferrioxamine that has formula C25H48N6O8. C25H48N6O8 CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN CHEBI:4356 DFO Deferoxamin Deferrioxamine Desferrioxamine InChI=1/C25H48N6O8/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34)/f/h27-28H InChIKey=UBQYURCVBFRUQT-VEORKLDJCD N'-{5-[acetyl(hydroxy)amino]pentyl}-N-(5-{4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanamido}pentyl)-N-hydroxybutanediamide deferoxamina deferoxamine deferoxaminum deferrioxamine B http://www.ebi.ac.uk/efo/EFO_0001518 lisinopril (S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline A dipeptide that has formula C21H31N3O5. C21H31N3O5 CHEBI:43755 InChI=1/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1/f/h26,28H InChIKey=RLAWWYSOJDYHDC-YMXGEOMKDH James Malone N(2)-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O [N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE http://www.ebi.ac.uk/efo/EFO_0001566 lisinopril anhydrous methotrexate 4-amino-10-methylfolic acid 4-amino-N(10)-methylpteroylglutamic acid A pteridine that has formula C20H22N8O5. C20H22N8O5 CHEBI:44185 CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O Emtexate InChI=1/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1/f/h25,29,32H,21-22H2 InChIKey=FBOZXECLQNJBKD-SGDZJVHDDX James Malone Ledertrexate MTX N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-glutamic acid N-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]-L-glutamic acid N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid Rheumatrex Trexall http://www.ebi.ac.uk/efo/EFO_0001572 methotrexatum metotrexato hydroxyurea An urea that has formula CH4N2O2. CH4N2O2 CHEBI:44423 Hydroxycarbamid Hydroxyharnstoff InChI=1/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)/f/h3H,2H2 InChIKey=VSNHCAURESNICA-DTXNPOPMCG N-carbamoylhydroxylamine N-hydroxyurea NC(=O)NO carbamohydroxamic acid carbamohydroximic acid carbamoyl oxime carbamyl hydroxamate http://www.ebi.ac.uk/efo/EFO_0001554 hydrea hydroxycarbamide oxyurea propofol 2,6-Diisopropylphenol 2,6-bis(1-methylethyl)phenol 2,6-bis(propan-2-yl)phenol A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group. A phenol that has formula C12H18O. C12H18O CC(C)c1cccc(C(C)C)c1O CHEBI:44915 Diprivan Disoprivan Disoprofol InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3 InChIKey=OLBCVFGFOZPWHH-UHFFFAOYAE James Malone Rapinovet http://www.ebi.ac.uk/efo/EFO_0001599 propofolum 1,10-phenanthroline 4,5-diazaphenanthrene A phenanthroline that has formula C12H8N2. C12H8N2 CHEBI:44975 Ele Holloway InChI=1/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H InChIKey=DGEZNRSVGBDHLK-UHFFFAOYAW James Malone c1cnc2c(c1)ccc1cccnc21 http://www.ebi.ac.uk/efo/EFO_0002483 o-Phenanthroline orthophenanthroline phen pentamidine 1,5-bis(4-amidinophenoxy)pentane 4,4'-(1,5-pentanediylbis(oxy))bis-benzenecarboximidamide 4,4'-(pentamethylenedioxy)dibenzamidine 4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide A carboxamidine that has formula C19H24N4O2. C19H24N4O2 CHEBI:45081 InChI=1/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23)/f/h20,22H,21,23H2 InChIKey=XDRYMKDFEDOLFX-JODGMDMNCA NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1 http://www.ebi.ac.uk/efo/EFO_0001590 p,p'-(pentamethylenedioxy)dibenzamidine diclofenac sodium (o-(2,6-dichloroanilino)phenyl)acetic acid monosodium salt (o-(2,6-dichloroanilino)phenyl)acetic acid sodium salt 2-((2,6-dichlorophenyl)amino)benzeneacetic acid monosodium salt An organic sodium salt that has formula C14H10Cl2NNaO2. C14H10Cl2NNaO2 C14H10Cl2NO2.Na CHEBI:4509 InChI=1/C14H11Cl2NO2.Na/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1/fC14H10Cl2NO2.Na/q-1;m InChIKey=KPHWPUGNDIVLNH-VDPPZFTLCG The sodium salt of diclofenac. [Na+].[O-]C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl http://www.ebi.ac.uk/efo/EFO_0001520 sodium (o-((2,6-dichlorophenyl)amino)phenyl)acetate sodium (o-(2,6-dichloroanilino)phenyl)acetate sodium {2-[(2,6-dichlorophenyl)amino]phenyl}acetate imatinib 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE 4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide A N-methylpiperazine that has formula C29H31N7O. C29H31N7O CHEBI:45783 CN1CCN(CC1)Cc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1 InChI=1/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)/f/h32,34H InChIKey=KTUFNOKKBVMGRW-RPGFEBOUCX James Malone STI 571 alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide http://www.ebi.ac.uk/efo/EFO_0001555 taxol (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha R*,betaS*),11alpha,12alpha,12balpha))-beta-(Benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester 4alpha,10beta-bis(acetyloxy)-13alpha-[(2S,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyloxy]-1,7beta-dihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine Antineoplastic agent isolated from the bark of the Pacific yew tree, Taxus brevifolia. Antineoplastic agent isolated from the bark of the Pacific yew tree, Taxus brevifolia. Note that the use of the name taxol is now limited, as Taxol is a registered trade mark. C47H51NO14 CHEBI:45863 InChI=1/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1/f/h48H InChIKey=RCINICONZNJXQF-GXKQXQCDDN James Malone Paclitaxel Taxol A [H][C@]12[C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c4ccccc4)c4ccccc4)C(C)=C([C@@H](OC(C)=O)C(=O)[C@]1(C)[C@@H](O)C[C@H]1OC[C@@]21OC(C)=O)C3(C)C http://www.ebi.ac.uk/efo/EFO_0001622 trifluoperazine 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine A phenothiazine derivative having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. A phenothiazine that has formula C21H24F3N3S. C21H24F3N3S CHEBI:45951 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 InChIKey=ZEWQUBUPAILYHI-UHFFFAOYAS James Malone http://www.ebi.ac.uk/efo/EFO_0001631 trifluoperazina trifluoperazinum trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine trifluoroperazine trifluperazine trichostatin A (2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide A trichostatin that has formula C17H22N2O3. C17H22N2O3 CHEBI:46024 C[C@@H](C(=O)c1ccc(cc1)N(C)C)\\C=C(C)\\C=C\\C(=O)NO InChI=1/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1/f/h18H InChIKey=RTKIYFITIVXBLE-LPBLKGKXDH James Malone TSA http://www.ebi.ac.uk/efo/EFO_0001630 fluconazole 2,4-difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL 2-(2,4-difluorophenyl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol 2-(2,4-difluorophenyl)-1,3-di-1H-1,2,4-triazol-1-ylpropan-2-ol 20627 627 86386-73-4 A radiolabelled urea molecule used to diagnose stomach ulcers caused by Heliobacter pylori. In the presence of H. pylori, urea C-13 is metabolized by urease to produce ammonia and radioactive carbon dioxide at the interface between the gastric epithelium and lumen. The radioactive carbon dioxide is absorbed in the blood and is detected when exhaled in the breath. A radiolabelled urea molecule used to diagnose stomach ulcers caused by Heliobacter pylori. In the presence of H. pylori, urea C-13 is metabolized by urease to produce ammonia and radioactive carbon dioxide at the interface between the gastric epithelium and lumen. The radioactive carbon dioxide is absorbed in the blood and is detected when exhaled in the breath.[accessedResource: C13H12F2N6O][accessDate: 05-04-2011] A tertiary alcohol that has formula C13H12F2N6O. A triazole that has formula C13H12F2N6O. Biozolene C13 Urea C13 Urea[accessedResource: C13H12F2N6O][accessDate: 05-04-2011] C13H12F2N6O C13H12F2N6O Diflucan Elazor Helicosol Helicosol[accessedResource: C13H12F2N6O][accessDate: 05-04-2011] InChI=1/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2 InChIKey=RFHAOTPXVQNOHP-UHFFFAOYAZ OC(Cn1cncn1)(Cn1cncn1)c1ccc(F)cc1F Triflucan UREA, C-13 UREA, C-13[accessedResource: C13H12F2N6O][accessDate: 05-04-2011] Urea C-13 Urea C-13[accessedResource: C13H12F2N6O][accessDate: 05-04-2011] obsolete_paracetamol 4'-hydroxyacetanilide 4-(Acetylamino)phenol 4-acetamidophenol A derivative of phenol which has an acetamido substituent located para to the phenolic -OH group. APAP Acenol Acetaminophen An acetamide that has formula C8H9NO2. C8H9NO2 CC(=O)Nc1ccc(O)cc1 CHEBI:46195 InChI=1/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)/f/h9H InChIKey=RZVAJINKPMORJF-BGGKNDAXCW James Malone N-(4-hydroxyphenyl)acetamide N-acetyl-p-aminophenol Tylenol acetaminofen acetaminophene http://www.ebi.ac.uk/efo/EFO_0001589 p-Acetylaminophenol p-acetamidophenol p-acetaminophenol p-hydroxyacetanilide p-hydroxyphenolacetamide paracetamolum duplicated chebi import 5-fluorouracil 5-FU 5-Fluoropyrimidine-2,4-dione 5-fluoropyrimidine-2,4(1H,3H)-dione An organofluorine compound that has formula C4H3FN2O2. C4H3FN2O2 CHEBI:46345 Ele Holloway Fc1c[nH]c(=O)[nH]c1=O Fluorouracil InChI=1/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)/f/h6-7H InChIKey=GHASVSINZRGABV-ZDKSUBDRCT James Malone http://www.ebi.ac.uk/efo/EFO_0001474 http://www.ebi.ac.uk/efo/EFO_0002488 asbestos Asbest CHEBI:46661 Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. asbesto http://www.ebi.ac.uk/efo/EFO_0001490 polyethylene glycol (C2H4O)n 1,2-ethanediol homopolymer 25322-68-3 27862 A polymer composed of repeating ethyleneoxy units. C2 Mouse C2 Mouse[accessedResource: C2H6O2][accessDate: 05-04-2011] C2H6O2 C2[accessedResource: C2H6O2][accessDate: 05-04-2011] Macrogol PEG PEO POE Polyaethylenglykol Polyaethylenglykole alpha,omega-hydroxypoly(ethylene oxide) alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl) alpha-hydro-omega-hydroxypoly(oxyethylene) ethylene glycol ethylene glycol homopolymer ethylene glycol polymer poly(ethylene glycol) poly(ethyleneoxide) poly(oxyethylene) polyethylene glycols polyethylene oxide polyoxyethylene S-[2,3-bis(palmitoyloxy)propyl]-Cys-Ser-Lys-Lys-Lys-Lys A diacyl lipopeptide that has formula C65H126N10O12S. C65H126N10O12S CCCCCCCCCCCCCCCC(=O)OCC(CSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)OC(=O)CCCCCCCCCCCCCCC CHEBI:46889 InChI=1/C65H126N10O12S/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-41-58(77)86-48-51(87-59(78)42-28-26-24-22-20-18-16-14-12-10-8-6-4-2)49-88-50-52(70)60(79)75-57(47-76)64(83)73-54(38-30-34-44-67)62(81)71-53(37-29-33-43-66)61(80)72-55(39-31-35-45-68)63(82)74-56(65(84)85)40-32-36-46-69/h51-57,76H,3-50,66-70H2,1-2H3,(H,71,81)(H,72,80)(H,73,83)(H,74,82)(H,75,79)(H,84,85)/t51?,52-,53-,54-,55-,56-,57-/m0/s1/f/h71-75,84H InChIKey=LJUIOEFZFQRWJG-URZMOCQLDI Pam2CSK4 S-[2,3-bis(hexadecanoyloxy)propyl]-L-cysteinyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-L-lysine S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-[R]-cysteinyl-[S]-seryl-[S]-lysyl-[S]-lysyl-[S]-lysyl-[S]-lysine S-[2,3-bis(palmitoyloxy)propyl]-L-cysteinyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-L-lysine http://www.ebi.ac.uk/efo/EFO_0001607 1-4-dioxane 1,4-DIETHYLENE DIOXIDE 1,4-dioxacyclohexane 1,4-dioxane 1,4-dioxane 123-91-1 20533 533 A dioxane that has formula C4H8O2. C1COCCO1 C4H8O2 C4H8O2 C4[accessedResource: C4H8O2][accessDate: 05-04-2011] Complement C4 Complement C4 Measurement Complement C4 Measurement[accessedResource: C4H8O2][accessDate: 05-04-2011] Complement C4[accessedResource: C4H8O2][accessDate: 05-04-2011] Complement Component-4 Complement component-4 (1744 aa, ~193 kDa) is part of the complement cascade, which mediates the innate immune response to infection. The full length protein is a precursor that can is secreted as a trimeric molecule containing an alpha, beta and gamma chain. When the complement cascade is initiated, the protein is cleaved. This proteolysis releases both the alpha chain, C4 anaphylatoxin, which stimulates inflammation, and a dimer of the beta and gamma chains, which mediates the interaction between the antigen-antibody complex and other complement components. Dioxan-1,4 InChI=1/C4H8O2/c1-2-6-4-3-5-1/h1-4H2 InChIKey=RYHBNJHYFVUHQT-UHFFFAOYAN The determination of the amount of complement C4 present in a sample. The determination of the amount of complement C4 present in a sample.[accessedResource: C4H8O2][accessDate: 05-04-2011] di(ethylene oxide) glycol ethylene ether p-Dioxane tetrahydro-1,4-dioxin tetrahydro-p-dioxin tetrahydro-para-dioxin diclofenac 15307-86-5 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position. A non-steroidal anti-inflammatory drug (NSAID), administered primarily as its sodium salt. A non-steroidal anti-inflammatory drug (NSAID), administered primarily as its sodium salt. C14H11Cl2NO2 InChI=1/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)/f/h18H InChIKey=DCOPUUMXTXDBNB-GPQMBLKYCR OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl [2-(2,6-dichloroanilino)phenyl]acetic acid diclofenac acid diclofenaco diclofenacum {2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid cefazolin (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 25953-19-9 3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-7beta-[(1H-tetrazol-1-ylacetyl)amino]-3,4-didehydrocepham-4-carboxylic acid A cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side groups. C14H14N8O4S3 CEZ Cefamezin Cephamezine Cephazolidin Cephazolin Cephazoline InChI=1/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1/f/h16,25H InChIKey=MLYYVTUWGNIJIB-JIWNMBEODB [H][C@]12SCC(CSc3nnc(C)s3)=C(N1C(=O)[C@H]2NC(=O)Cn1cnnn1)C(O)=O cefazolina cefazoline cefazolinum caspofungin (4R,5S)-5-((2-aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0 179463-17-3 A semisynthetic cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. C52H88N10O15 InChI=1/C52H88N10O15/c1-5-28(2)24-29(3)12-10-8-6-7-9-11-13-39(69)56-34-26-38(68)46(55-22-21-54)60-50(75)43-37(67)19-23-61(43)52(77)41(36(66)18-20-53)58-49(74)42(45(71)44(70)31-14-16-32(64)17-15-31)59-48(73)35-25-33(65)27-62(35)51(76)40(30(4)63)57-47(34)72/h14-17,28-30,33-38,40-46,55,63-68,70-71H,5-13,18-27,53-54H2,1-4H3,(H,56,69)(H,57,72)(H,58,74)(H,59,73)(H,60,75)/t28?,29?,30-,33-,34+,35+,36-,37+,38-,40+,41+,42+,43+,44+,45+,46+/m1/s1/f/h56-60H InChIKey=JYIKNQVWKBUSNH-FUOOKJLVDM N-{(2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-12-[(2-aminoethyl)amino]-20-[(1R)-3-amino-1-hydroxypropyl]-23-[(1S2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide [H][C@@]1(C[C@@H](O)[C@@H](NCCN)NC(=O)[C@@H]2[C@@H](O)CCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@]2([H])C[C@@H](O)CN2C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)c1ccc(O)cc1)[C@H](O)CCN)NC(=O)CCCCCCCCC(C)CC(C)CC dibenzazepines CHEBI:47804 Ele Holloway James Malone dibenzazepine dibenzoazepine dibenzoazepines http://www.ebi.ac.uk/efo/EFO_0002491 sulforaphane 1-isothiocyanato-4-(methylsulfinyl)butane 4-isothiocyanatobutyl methyl sulfoxide A sulfoxide that has formula C6H11NOS2. C6H11NOS2 CHEBI:47807 CS(=O)CCCCN=C=S InChI=1/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3 InChIKey=SUVMJBTUFCVSAD-UHFFFAOYAY Sulforafan http://www.ebi.ac.uk/efo/EFO_0001617 HC toxin CHEBI:48028 InChI=1/C21H32N4O6/c1-12-18(27)22-13(2)19(28)24-14(7-4-3-5-9-16(26)17-11-31-17)21(30)25-10-6-8-15(25)20(29)23-12/h12-15,17H,3-11H2,1-2H3,(H,22,27)(H,23,29)(H,24,28)/t12-,13+,14-,15+,17?/m0/s1/f/h22-24H InChIKey=GNYCTMYOHGBSBI-SWJGNPKQDK [H][C@]12CCCN1C(=O)[C@H](CCCCCC(=O)C1CO1)NC(=O)[C@@H](C)NC(=O)[C@H](C)NC2=O http://www.ebi.ac.uk/efo/EFO_0001551 antiseptic drug CHEBI:48218 James Malone http://www.ebi.ac.uk/efo/EFO_0001874 serotonergic antagonist 5-HT antagonists 5-hydroxytryptamine antagonists CHEBI:48279 Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. James Malone antiserotonergic agents http://www.ebi.ac.uk/efo/EFO_0001875 serotonin antagonists serotonin blockaders polar solvent CHEBI:48354 James Malone http://www.ebi.ac.uk/efo/EFO_0001876 polar aprotic solvent CHEBI:48358 James Malone http://www.ebi.ac.uk/efo/EFO_0001877 amphiprotic solvent (13Z)-docos-13-enoic acid 3,3,6,6,8a-Pentamethyl-tetrahydro-1,8-dioxa-4a-aza-naphthalene 3,3,6,6,8a-pentamethyl-1,8-dioxaquinolizidine 3,3,6,6,8a-pentamethyltetrahydro-1,8-dioxa-4a-azanaphthalene 3,3,7,7,9a-pentamethyltetrahydro-2H,6H-[1,3]oxazino[2,3-b][1,3]oxazine A docosenoic acid that has formula C22H42O2. An oxazinooxazine that has formula C12H23NO2. C12H23NO2 CC1(C)COC2(C)OCC(C)(C)CN2C1 CHEBI:4836 InChI=1/C12H23NO2/c1-10(2)6-13-7-11(3,4)9-15-12(13,5)14-8-10/h6-9H2,1-5H3 InChIKey=HXCGBGUJRISVDD-UHFFFAOYAH James Malone erucic acid http://www.ebi.ac.uk/efo/EFO_0001878 olmesartan 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid 4-(hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid A biphenylyltetrazole that has formula C24H26N6O3. C24H26N6O3 CCCc1nc(c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)(C)O CHEBI:48416 InChI=1/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)/f/h26,31H InChIKey=VTRAEEWXHOVJFV-NEQLIHFBCB http://www.ebi.ac.uk/efo/EFO_0001587 obsolete_dopaminergic antagonist 2.23 duplicates import from CHEBI lithium chloride A lithium salt that has formula ClLi. A metal chloride salt with a Li(+) counterion. CHEBI:48607 ClLi InChI=1/ClH.Li/h1H;/q;+1/p-1/fCl.Li/h1h;/q-1;m InChIKey=KWGKDLIKAYFUFQ-HPRMROJMCO LiCl Lithiumchlorid chlorure de lithium cloruro de litio http://www.ebi.ac.uk/efo/EFO_0001567 lithii chloridum sodium selenite 10102-18-8 12077 32077 A selenite salt that has formula Na2O3Se. InChI=1/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2/f2Na.O3Se/q2m;-2 InChIKey=BVTBRVFYZUCAKH-IADKYXLJCK Na2O3Se Na2O3Se Natriumselenit [Na+].[Na+].[O-][Se]([O-])=O disodium selenite disodium selenite benzothiadiazole benzothiadiazoles cholinergic antagonist Anticholinergika Anticholinergikum Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. CHEBI:48873 James Malone acetylcholine antagonists acetylcholine receptor antagonist agent anticholinergique agente anticolinergico agentes anticolinergicos anticholinergic agents anticholinergics anticholinergiques anticolinergicos cholinergic-blocking agents http://www.ebi.ac.uk/efo/EFO_0001880 muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. Antimuskarinika Antimuskarinikum CHEBI:48876 James Malone agente antimuscarinico agentes antimuscarinicos agents antimuscariniques antimuscarinic agents antimuscarinicos http://www.ebi.ac.uk/efo/EFO_0001881 muscarinic acetylcholine receptor antagonist muscarinic antagonists 1,1'-azobis(N,N-dimethylformamide) 10465-78-8 3-(N,N-dimethylcarbamoylimido)-1,1-dimethylurea A monoazo compound that has formula C6H12N4O2. C6H12N4O2 CN(C)C(=O)N=NC(=O)N(C)C Diamide InChI=1/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3 InChIKey=VLSDXINSOMDCBK-UHFFFAOYAG N,N,N',N'-tetramethylazobisformamide N,N,N',N'-tetramethylazodicarboxamide N,N,N',N'-tetramethylazoformamide N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide TMAD azodicarboxylic acid bis-dimethylamide diazenedicarboxylic acid bis(N,N-dimethylamide) tetramethyldiazenedicarboxamide 17alpha-ethinylestradiol (17beta)-17-ethynylestra-1(10),2,4-triene-3,17-diol 11-Eicosenoic Acid 11-Eicosenoic Acid[accessedResource: C20H24O2][accessDate: 05-04-2011] 17-ethinyl-3,17-estradiol 17-ethinyl-3,17-oestradiol 17-ethinylestradiol 17alpha-Ethinyl estradiol 17alpha-ethynylestra-1,3,5(10)-triene-3,17beta-diol 17alpha-ethynylestradiol 20576 57-63-6 576 A 17-hydroxy steroid that has formula C20H24O2. A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration. A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration.[accessedResource: C20H24O2][accessDate: 05-04-2011] C20:1 n-9 cis C20:1 n-9 cis[accessedResource: C20H24O2][accessDate: 05-04-2011] C20H24O2 C20H24O2 Cis-icos-11-enoic Cis-icos-11-enoic[accessedResource: C20H24O2][accessDate: 05-04-2011] EE2; ethinylestradiol Ethinyl estradiol Ethinylestradiol Ethynyl estradiol Fatty Acid 20:1 n-9 Fatty Acid 20:1 n-9[accessedResource: C20H24O2][accessDate: 05-04-2011] Gondoic Acid Gondoic Acid[accessedResource: C20H24O2][accessDate: 05-04-2011] InChI=1/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1 InChIKey=BFPYWIDHMRZLRN-SLHNCBLABF [H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)C#C)[C@]1([H])CCc1cc(O)ccc21 ethinyloestradiol etoposide (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside (8aR,9R)-9-[4-hydroxy-3,5-bis(methyloxy)phenyl]-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside 1,2,5,6-Dibenzanthracene 1,2,5,6-Dibenzanthracene[accessedResource: C29H32O13][accessDate: 05-04-2011] 24/01/1963 33419-42-0 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside) 4-demethylepipodophyllotoxin beta-D-ethylideneglucoside 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one A beta-D-glucoside that has formula C29H32O13. C29H32O13 C29H32O13 ETOP Eposin Etopophos Etoposido InChI=1/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1 InChIKey=VJJPUSNTGOMMGY-MRVIYFEKBZ Lastet Toposar VP-16 Vepesid [H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(O)c(OC)c1)c1cc3OCOc3cc1[C@H]2O[C@@H]1O[C@@H]2CO[C@@H](C)O[C@H]2[C@H](O)[C@H]1O etoposidum trans-Etoposide eugenol 1,3,4-Eugenol 1-Hydroxy-2-methoxy-4-allylbenzene 1-Hydroxy-2-methoxy-4-prop-2-enylbenzene 1-Hydroxy-2-methoxy-4-propenylbenzene 1-allyl-3-methoxy-4-hydroxybenzene 1-allyl-4-hydroxy-3-methoxybenzene 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethylethanaminium 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethylethanaminium[accessedResource: C10H12O2][accessDate: 05-04-2011] 2-Hydroxy-5-allylanisole 2-Methoxy-4-allylphenol 2-Methoxy-4-prop-2-enylphenol 2-methoxy-4-(2-propen-1-yl)phenol 2-methoxy-4-(prop-2-en-1-yl)phenol 20617 4-Allyl-1-hydroxy-2-methoxybenzene 4-Allylcatechol-2-methyl ether 4-Allylguaiacol 4-Hydroxy-3-methoxy-1-allylbenzene 4-allyl-2-methoxyphenol 4-allyl-2-methoxyphenol 617 97-53-0 A guaiacol with an allyl chain substituted para to the hydroxy group. Aclatonium Aclatonium[accessedResource: C10H12O2][accessDate: 05-04-2011] Aconitum ferox Root Allylguaiacol C10H12O2 C10H12O2 COc1cc(CC=C)ccc1O Caryophyllic acid Choline Lactate, Acetate Choline Lactate, Acetate[accessedResource: C10H12O2][accessDate: 05-04-2011] Ethanaminium, 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethyl- Ethanaminium, 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethyl-[accessedResource: C10H12O2][accessDate: 05-04-2011] Eugenic acid InChI=1/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 InChIKey=RRAFCDWBNXTKKO-UHFFFAOYAJ p-Allylguaiacol p-Eugenol methyleugenol 1,2-Dimethoxy-4-(2-propenyl)benzene 1,2-dimethoxy-4-(prop-2-en-1-yl)benzene 25607 4-allyl-1,2-dimethoxybenzene 5607 93-15-2 A phenylpropanoid that has formula C11H14O2. A radiotracer consisting of choline labeled with the positron-emitting isotope carbon C 11 with potential imaging use. Upon administration, C-11 choline incorporates into tumor cells through an active, carrier-mediated transport mechanism for choline and then is phosphorylated intracellularly by choline kinase, an enzyme frequently upregulated in human tumors, yielding phosphoryl C-11 choline. In turn, phosphoryl C-11 choline is integrated into phospholipids in the cell membrane as part of phosphatidylcholine. As the proliferation of cancer cells is much higher than normal cells, tumor cells exhibit an increased rate of C-11 choline uptake and incorporation, allowing tunor imaging with positron emission tomography (PET). A radiotracer consisting of choline labeled with the positron-emitting isotope carbon C 11 with potential imaging use. Upon administration, C-11 choline incorporates into tumor cells through an active, carrier-mediated transport mechanism for choline and then is phosphorylated intracellularly by choline kinase, an enzyme frequently upregulated in human tumors, yielding phosphoryl C-11 choline. In turn, phosphoryl C-11 choline is integrated into phospholipids in the cell membrane as part of phosphatidylcholine. As the proliferation of cancer cells is much higher than normal cells, tumor cells exhibit an increased rate of C-11 choline uptake and incorporation, allowing tunor imaging with positron emission tomography (PET).[accessedResource: C11H14O2][accessDate: 05-04-2011] C-11 Choline C-11 Choline[accessedResource: C11H14O2][accessDate: 05-04-2011] C11 Choline C11 Choline[accessedResource: C11H14O2][accessDate: 05-04-2011] C11H14O2 C11H14O2 COc1ccc(CC=C)cc1OC Carbon C 11 Choline Carbon C 11 Choline[accessedResource: C11H14O2][accessDate: 05-04-2011] Carbon C11 Choline Eugenol methyl ether InChI=1/C11H14O2/c1-4-5-9-6-7-10(12-2)11(8-9)13-3/h4,6-8H,1,5H2,2-3H3 InChIKey=ZYEMGPIYFIJGTP-UHFFFAOYAJ Methyl eugenol O-Methyleugenol dasatinib 302962-49-8 40979 A N-(2-hydroxyethyl)piperazine that has formula C22H26ClN7O2S. A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration. A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration.[accessedResource: C22H26ClN7O2S][accessDate: 05-04-2011] BMS Dasatinib Brassidic Acid Brassidic Acid[accessedResource: C22H26ClN7O2S][accessDate: 05-04-2011] C22:1, n-9 trans C22:1, n-9 trans[accessedResource: C22H26ClN7O2S][accessDate: 05-04-2011] C22H26ClN7O2S C22H26ClN7O2S Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1 Fatty Acid 22:1 n-9 trans Fatty Acid 22:1 n-9 trans[accessedResource: C22H26ClN7O2S][accessDate: 05-04-2011] Fatty Acid trans 22:1 n-9 Fatty Acid trans 22:1 n-9[accessedResource: C22H26ClN7O2S][accessDate: 05-04-2011] InChI=1/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)/f/h27-28H InChIKey=ZBNZXTGUTAYRHI-VEORKLDJCJ N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide Trans docos-13-enoic Acid Trans docos-13-enoic Acid[accessedResource: C22H26ClN7O2S][accessDate: 05-04-2011] dasatinibum exemestane 107868-30-4 6-methyleneandrosta-1,4-diene-3,17-dione 6-methylideneandrosta-1,4-diene-3,17-dione Androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group.a selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer. C20H24O2 InChI=1/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1 InChIKey=BFYIZQONLCFLEV-DAELLWKTBA [H][C@@]12CC(=C)C3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)C(=O)CC[C@@]21[H] exemestano exemestanum copper(II) chloride 7447-39-4 Chloride of copper in which the metal is in the +2 oxidation state. Cl2Cu Cl[Cu]Cl Coclor Copper bichloride Copper chloride Copper chloride (CuCl2) Copper dichloride Copper(2+) chloride Copper(II) chloride (1:2) Copper(II) chloride dihydrate Coppertrace CuCl2 Cupric chloride Cupric chloride anhydrous Cupric chloride dihydrate Cupric dichloride InChI=1/2ClH.Cu/h2*1H;/q;;+2/p-2/f2Cl.Cu/h2*1h;/q2*-1;m InChIKey=ORTQZVOHEJQUHG-KPGHBSTOCA copper(2+) dichloride diazepam 439-14-5 7-chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one A 1,4-benzodiazepinone that has formula C16H13ClN2O. C16H13ClN2O CN1C(=O)CN=C(c2ccccc2)c2cc(Cl)ccc12 InChI=1/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 InChIKey=AAOVKJBEBIDNHE-UHFFFAOYAM Valium methyl diazepinone lapatinib A quinazoline that has formula C29H26ClFN4O4S. C29H26ClFN4O4S CHEBI:49603 CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1 GW 572016 InChI=1/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)/f/h35H InChIKey=BCFGMOOMADDAQU-CSKMVECVCB N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine N-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-[5-({[2-(methanesulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE Tykerb http://www.ebi.ac.uk/efo/EFO_0001562 indomethacin 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid An indole-3-acetic acid that has formula C19H16ClNO4. C19H16ClNO4 CHEBI:49662 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)/f/h22H InChIKey=CGIGDMFJXJATDK-QWOVJGMICU Indocin Indometacin James Malone [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid http://www.ebi.ac.uk/efo/EFO_0001557 gefitinib 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline A quinazoline that has formula C22H24ClFN4O3. C22H24ClFN4O3 CHEBI:49668 COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1 InChI=1/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)/f/h27H InChIKey=XGALLCVXEZPNRQ-LELJVTLKCM Iressa James Malone N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine ZD 1839 http://www.ebi.ac.uk/efo/EFO_0001541 methylmercury A methylmercury compound that has formula CH3Hg. CH3Hg CHEBI:49747 C[Hg+] Ele Holloway InChI=1/CH3.Hg/h1H3;/q;+1 InChIKey=DBUXSCUEGJMZAE-UHFFFAOYAW METHYL MERCURY ION Methylmercury II Tomasz Adamusiak [HgCH3](+) [HgMe](+) http://www.ebi.ac.uk/efo/EFO_0002730 methylmercury ion(1+) methylmercury(1+) methylmercury(II) cation monomethylmercury cation tetraethylenepentamine 1,11-Diamino-3,6,9-triazaundecane 1,4,7,10,13-pentaazatridecane 3,6,9-triazaundecamethylenediamine 3,6,9-triazaundecane-1,11-diamine A polyazaalkane that has formula C8H23N5. C8H23N5 CHEBI:49798 InChI=1/C8H23N5/c9-1-3-11-5-7-13-8-6-12-4-2-10/h11-13H,1-10H2 InChIKey=FAGUFWYHJQFNRV-UHFFFAOYAH N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-1,2-ethanediamine N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine NCCNCCNCCNCCN TEPA Tetraethylenpentamin http://www.ebi.ac.uk/efo/EFO_0001623 tetren imidazole 1H-imidazol-3-ium 1H-imidazole 288-32-4 29616 C3 Gene C3 Gene[accessedResource: C3H4N2][accessDate: 05-04-2011] C3H4N2 C3H5N2 C3[accessedResource: C3H4N2][accessDate: 05-04-2011] Complement Component 3 Gene Complement Component 3 Gene[accessedResource: C3H4N2][accessDate: 05-04-2011] H2im(+) InChI=1/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)/p+1/fC3H5N2/h4-5H/q+1 InChIKey=RAXXELZNTBOGNW-APSIDXPICG The cation resulting from protonation at the 3-position of 1H-imidazole. This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade. This gene plays a regulatory role in the complement pathway, which is comprised of a complex proteolytic cascade.[accessedResource: C3H4N2][accessDate: 05-04-2011] c1c[nH+]c[nH]1 imidazolium imidazolium cation imidazolium ion S-nitrosoglutathione 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethylethanaminium 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethylethanaminium[accessedResource: C10H16N4O7S][accessDate: 05-04-2011] 20613 40613 57564-91-7 A glutathione derivative that has formula C10H16N4O7S. Aclatonium Aclatonium[accessedResource: C10H16N4O7S][accessDate: 05-04-2011] Aconitum ferox Root C10H16N4O7S C10H16N4O7S Choline Lactate, Acetate Choline Lactate, Acetate[accessedResource: C10H16N4O7S][accessDate: 05-04-2011] Ethanaminium, 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethyl- Ethanaminium, 2-(2-(Acetyloxy)-1-Oxopropoxy)-N,N,N-Trimethyl-[accessedResource: C10H16N4O7S][accessDate: 05-04-2011] GSNO InChI=1/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1/f/h12-13,16,19H InChIKey=HYHSBSXUHZOYLX-MSUGUKDWDF L-gamma-glutamyl-S-nitroso-L-cysteinylglycine N-(N-L-gamma-glutamyl-S-nitroso-L-cysteinyl)glycine N[C@@H](CCC(=O)N[C@@H](CSN=O)C(=O)NCC(O)=O)C(O)=O SNOG g-glutamyl-S-nitrosocysteinylglycine glutathione thionitrite nitrosoglutathione bucladesine 3',5'-cyclic AMP dibutyrate 6-N-butanoyl-2'-O-butanoyladenosine 3',5'-(hydrogen phosphate) C18H24N5O8P CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1OC(=O)CCC CHEBI:50095 InChI=1/C18H24N5O8P/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24)/t10-,14-,15-,18-/m1/s1/f/h22,26H InChIKey=CJGYSWNGNKCJSB-NOICQAOIDM N(6),2'-O-dibutyryl cAMP N(6),2'-O-dibutyryl cyclic AMP N(6),O(2')-dibutyryl adenosine 3',5'-cyclic monophosphate N(6),O(2')-dibutyryl-3',5'-cyclic AMP N(6),O(2')-dibutyryladenosine 3',5'-monophosphate bucladesina bucladesinum dibutyryl 3',5'-cyclic AMP dibutyryl adenosine 3',5'-cyclic phosphate dibutyryl adenosine 3',5'-monophosphate dibutyryl cAMP dibutyryl cyclic 3',5'-adenylic acid dibutyryl cyclic AMP dibutyryl cyclic adenosine 3',5'-monophosphate dibutyryl-3',5'-AMP dibutyryladenosine 3',5'-cyclic monophosphate dibutyryladenosine cyclic monophosphate http://www.ebi.ac.uk/efo/EFO_0001495 excitatory amino acid agonist An agent that binds to and activates excitatory amino acid receptors. CHEBI:50103 James Malone excitatory amino acid agonists http://www.ebi.ac.uk/efo/EFO_0001882 sex hormone Any hormone that is responsible for controlling sexual characteristics and reproductive function. CHEBI:50112 Geschlechtshormon Geschlechtshormone James Malone Sexualhormon Sexualhormone hormone sexuelle hormones sexuelles http://www.ebi.ac.uk/efo/EFO_0001883 sex hormones androgen A steroid hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors. Androgene CHEBI:50113 James Malone androgenes androgeno androgenos androgens http://www.ebi.ac.uk/efo/EFO_0001484 estrogen A steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. Agents, Estrogenic Agents, Estrogenic[accessedResource: MSH:D004967][accessDate: 05-04-2011] Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds. Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.[accessedResource: MSH:D004967][accessDate: 05-04-2011] Compounds, Estrogenic Compounds, Estrogenic[accessedResource: MSH:D004967][accessDate: 05-04-2011] Estrogenic Agents Estrogenic Agents[accessedResource: MSH:D004967][accessDate: 05-04-2011] Estrogenic Compounds Estrogenic Compounds[accessedResource: MSH:D004967][accessDate: 05-04-2011] Estrogens Estrogens[accessedResource: MSH:D004967][accessDate: 05-04-2011] James Malone MSH:D004967 NIFSTD:nifext_5156 Oestrogen Tomasz Adamusiak estrogene estrogenes estrogenes Hormon estrogeno estrogenos http://www.ebi.ac.uk/efo/EFO_0001530 oestrogene oestrogenes oestrogens rosiglitazone 5-((4-(2-(methyl-2-pyridinylamino)ethoxy)phenyl)methyl)-2,4-thiazolidinedione 5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione A thiazolidenedione that has formula C18H19N3O3S. BRL-49653 C18H19N3O3S CHEBI:50122 CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 InChI=1/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)/f/h20H InChIKey=YASAKCUCGLMORW-UYBDAZJACF James Malone http://www.ebi.ac.uk/efo/EFO_0001605 rosiglitazona rosiglitazonum 5-aza-2'-deoxycytidine 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one 5-azadeoxycytidine A 2'-deoxyribonucleoside that has formula C8H12N4O4. C8H12N4O4 CHEBI:50131 InChI=1/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1/f/h9H2 InChIKey=XAUDJQYHKZQPEU-BRLQTKNBDS Nc1ncn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1 decitabine http://www.ebi.ac.uk/efo/EFO_0001473 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acid An indazole that has formula C15H10Cl2N2O2. C15H10Cl2N2O2 CHEBI:50138 DICA Doridamina InChI=1/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)/f/h20H InChIKey=WDRYRZXSPDWGEB-UYBDAZJACL Lonidamin OC(=O)c1nn(Cc2ccc(Cl)cc2Cl)c2ccccc12 diclondazolic acid http://www.ebi.ac.uk/efo/EFO_0001466 lonidamina lonidamine lonidaminum sodium pyruvate An organic sodium salt that has formula C3H3NaO3. C3H3NaO3 CHEBI:50144 InChI=1/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1/fC3H3O3.Na/q-1;m InChIKey=DAEPDZWVDSPTHF-UFJSCRFPCI Natriumpyruvat [Na+].CC(=O)C([O-])=O http://www.ebi.ac.uk/efo/EFO_0001612 pyruvic acid, sodium salt sodium 2-oxopropanoate fenpropimorph 4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine 4-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine A morpholine that has formula C20H33NO. C20H33NO CC(CN1CC(C)OC(C)C1)Cc1ccc(cc1)C(C)(C)C CHEBI:50148 Corbel Ele Holloway InChI=1/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3 InChIKey=RYAUSSKQMZRMAI-UHFFFAOYAY James Malone Mistral http://www.ebi.ac.uk/efo/EFO_0002408 canrenoate 17beta-hydroxy-3-oxo-21a-homopregna-4,6-dien-21a-oate 3-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate A steroid acid anion that has formula C22H29O4. C22H29O4 CHEBI:50159 InChI=1/C22H30O4/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21,26)12-8-19(24)25/h3-4,13,16-18,26H,5-12H2,1-2H3,(H,24,25)/p-1/t16-,17+,18+,20+,21+,22-/m1/s1/fC22H29O4/q-1 InChIKey=PBKZPPIHUVSDNM-LKCFEDHXDC [H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)CCC([O-])=O)[C@]1([H])C=CC1=CC(=O)CC[C@]21C http://www.ebi.ac.uk/efo/EFO_0001499 motexafin gadolinium (PB-7-11-233'2'4)-bis(acetato-kappaO)(9,10-diethyl-20,21-bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-4,15-dimethyl-8,11-imino-3,6:16,13-dinitrilo-1,18-benzodiazacycloeicosine-5,14-dipropanolato-kappaN(1),kappaN(18),kappaN(23),kappaN(24),kappaN(25))gadolinium A metallotexaphyrin that has formula C52H72GdN5O14. C52H72GdN5O14 CCc1c(CC)c2C=C3C(CCCO)=C(C)C4=[N]3[Gd]356(OC(C)=O)(OC(C)=O)[N](=CC7=[N]3C(=Cc1n25)C(CCCO)=C7C)c1cc(OCCOCCOCCOC)c(OCCOCCOCCOC)cc1[N]6=C4 CHEBI:50161 Gd texaphyrin Gd-Tex InChI=1/C48H66N5O10.2C2H4O2.Gd/c1-7-35-36(8-2)40-28-42-38(12-10-14-55)34(4)46(53-42)32-50-44-30-48(63-26-24-61-22-20-59-18-16-57-6)47(62-25-23-60-21-19-58-17-15-56-5)29-43(44)49-31-45-33(3)37(11-9-13-54)41(52-45)27-39(35)51-40;2*1-2(3)4;/h27-32,54-55H,7-26H2,1-6H3;2*1H3,(H,3,4);/q-1;;;+3/p-2/b39-27-,40-28-,41-27-,42-28-,45-31-,46-32-,49-31+,49-43+,50-32+,50-44+;;;/fC48H66N5O10.2C2H3O2.Gd/qm;2*-1;m InChIKey=VAZLWPAHMORDGR-MPNKMPCTDC MGd Xcytrin bis(acetato-kappaO){3,3'-[4,5-diethyl-16,17-bis{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-10,23-dimethyl-13,20,25,26,27-pentaazapentacyclo[20.2.1.1(3,6).1(8,11).0(14,19)]heptacosa-1,3,5,7,9,11(26),12,14,16,18,20,22(25),23-tridecaene-9,24-diyl-kappa(5)N(13),N(20),N(25),N(26),N(27)]dipropan-1-olato}gadolinium gadolinium texaphyrin http://www.ebi.ac.uk/efo/EFO_0001575 dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. CHEBI:50177 James Malone dermatologic agent dermatologic drugs dermatological agent http://www.ebi.ac.uk/efo/EFO_0001884 (+)-dexrazoxane (+)-(S)-4,4'-Propylenedi-2,6-piperazinedione (+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane 24584-09-6 4,4'-(2S)-propane-1,2-diyldipiperazine-2,6-dione A razoxane that has formula C11H16N4O4. C11H16N4O4 C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1 Dextrorazoxane InChI=1/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1/f/h12-13H InChIKey=BMKDZUISNHGIBY-QVMQBSIXDF dexrazoxano dexrazoxanum anticoagulant An agent that prevents blood clotting. CHEBI:50249 James Malone anticoagulante anticoagulants http://www.ebi.ac.uk/efo/EFO_0001885 obsolete_topoisomerase I inhibitor 2.23 duplicates imported class cadmium sulfate 10124-36-4 20229 229 A cadmium salt that has formula CdO4S. Cadmiumsulfat CdO4S CdO4S CdSO4 InChI=1/Cd.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2/fCd.O4S/qm;-2 InChIKey=QCUOBSQYDGUHHT-ICYYQYRACL Kadmiumsulfat [Cd++].[O-]S([O-])(=O)=O cadmium monosulfate cadmium sulfate cadmium sulphate cadmium(2+) sulfate sulfate de cadmium sulfato de cadmio 1,9-dideoxyforskolin (3R,4aS,5S,6S,6aS,10aS,10bR)-3-ethenyl-6-hydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate (3R,4aS,5S,6S,6aS,10aS,10bR)-5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho(2,1-b)pyran-1-one (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10abeta,10balpha))-5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho(2,1-b)pyran-1-one 7beta-acetoxy-8,13-epoxy-6beta-hydroxylabd-14-en-11-one A labdane diterpenoid that has formula C22H34O5. C22H34O5 CHEBI:50295 Ele Holloway InChI=1/C22H34O5/c1-8-20(5)12-14(24)16-21(6)11-9-10-19(3,4)17(21)15(25)18(26-13(2)23)22(16,7)27-20/h8,15-18,25H,1,9-12H2,2-7H3/t15-,16+,17-,18-,20-,21+,22-/m0/s1 InChIKey=ZKZMDXUDDJYAIB-SUCLLAFCBT James Malone [H][C@@]12[C@H](O)[C@H](OC(C)=O)[C@@]3(C)O[C@](C)(CC(=O)[C@]3([H])[C@@]1(C)CCCC2(C)C)C=C http://www.ebi.ac.uk/efo/EFO_0002484 hemin A heme b that has formula C34H32ClFeN4O4. C34H32ClFeN4O4 CC1=C(CCC(O)=O)C2=[N]3C1=Cc1c(C)c(C=C)c4C=C5C(C)=C(C=C)C6=[N]5[Fe]3(Cl)(n14)n1c(=C6)c(C)c(CCC(O)=O)c1=C2 CHEBI:50385 Ele Holloway Haemin InChI=1/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;/fC34H32N4O4.Cl.Fe/h39,41H;1h;/q-2;-1;m InChIKey=BTIJJDXEELBZFS-MXZCRJNTDE James Malone chlorido(protoporphyrinato)iron(III) chloro(protoporphyrinato)iron(III) chloro[3,7,12,17-tetramethyl-8,13-divinylporphyrin-2,18-dipropanoato(2-)]iron(III) hemine http://www.ebi.ac.uk/efo/EFO_0002409 protohemin phospholipase A2 inhibitor CHEBI:50469 James Malone http://www.ebi.ac.uk/efo/EFO_0001887 phospholipase A2 inhibitors osmotic diuretic CHEBI:50504 Compound that increase urine volume by increasing the amount of osmotically active solute in the urine. It also increases the osmolarity of plasma. James Malone http://www.ebi.ac.uk/efo/EFO_0001888 sweetening agent CHEBI:50505 James Malone Substance that sweeten food, beverages, medications, etc. http://www.ebi.ac.uk/efo/EFO_0001889 arsenic oxides CHEBI:50527 James Malone arsenic oxide http://www.ebi.ac.uk/efo/EFO_0002004 cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor with specificity for cyclooxygenase 2. CHEBI:50629 COX-2 inhibitor James Malone http://www.ebi.ac.uk/efo/EFO_0001890 cyclooxygenase 1 inhibitor A cyclooxygenase inhibitor with specificity for cyclooxygenase 1. CHEBI:50630 COX-1 inhibitor James Malone http://www.ebi.ac.uk/efo/EFO_0001891 bone density conservation agent An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat metabolic bone diseases. CHEBI:50646 James Malone http://www.ebi.ac.uk/efo/EFO_0001892 alitretinoin (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid (9cis)-retinoic acid (9cis)-retinoic acid 08/03/5300 11-Eicosenoic Acid 11-Eicosenoic Acid[accessedResource: C20H28O2][accessDate: 05-04-2011] 20404 40404 9(Z)-Retinoic acid 9-cis retinoic acid 9-cis-Tretinoin A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration. A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl end, with the bond in the cis- configuration.[accessedResource: C20H28O2][accessDate: 05-04-2011] A retinoid that has formula C20H28O2. C20:1 n-9 cis C20:1 n-9 cis[accessedResource: C20H28O2][accessDate: 05-04-2011] C20H28O2 C20H28O2 CC(\\C=C\\C1=C(C)CCCC1(C)C)=C\\C=C\\C(C)=C\\C(O)=O Cis-icos-11-enoic Cis-icos-11-enoic[accessedResource: C20H28O2][accessDate: 05-04-2011] Fatty Acid 20:1 n-9 Fatty Acid 20:1 n-9[accessedResource: C20H28O2][accessDate: 05-04-2011] Gondoic Acid Gondoic Acid[accessedResource: C20H28O2][accessDate: 05-04-2011] InChI=1/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+/f/h21H InChIKey=SHGAZHPCJJPHSC-HMSKTFJBDV Panretin alitretinoina alitretinoine alitretinoinum folic acid reductase inhibitor CHEBI:50683 James Malone http://www.ebi.ac.uk/efo/EFO_0001893 nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. CHEBI:50733 Dietary Supplement Food Supplementation James Malone Nutritional supplement http://www.ebi.ac.uk/efo/EFO_0001894 estrogen receptor modulator A substance that possess antiestrogenic actions but can also produce estrogenic effects as well. It acts as complete or partial agonist or as antagonist. It can be either steroidal or nonsteroidal in structure. CHEBI:50739 James Malone http://www.ebi.ac.uk/efo/EFO_0001895 topoisomerase II inhibitor An inhibitor of DNA topoisomerase II, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. CHEBI:50750 James Malone http://www.ebi.ac.uk/efo/EFO_0001896 inhibitor of type II topoisomerase inhibitors of type II topoisomerase topoisomerase-II inhibitors estrogen receptor antagonist An antagonist at the estrogen receptor. CHEBI:50792 James Malone estrogen receptor antagonists http://www.ebi.ac.uk/efo/EFO_0001897 norflurazon 4-chloro-5-(methylamino)-2-(alpha,alpha,alpha-trifluoro-m-tolyl)-3(2H)-pyridazinone 4-chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]-3(2H)-pyridazinone 4-chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one A pyridazinone that has formula C12H9ClF3N3O. C12H9ClF3N3O CHEBI:50842 CNC1=C(Cl)C(=O)N(N=C1)c2cccc(c2)C(F)(F)F Ele Holloway InChI=1/C12H9ClF3N3O/c1-17-9-6-18-19(11(20)10(9)13)8-4-2-3-7(5-8)12(14,15)16/h2-6,17H,1H3 InChIKey=NVGOPFQZYCNLDU-UHFFFAOYAZ James Malone SAN 9789 Solicam Zorial http://www.ebi.ac.uk/efo/EFO_0002416 doxycycline (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 5-hydroxy-alpha-6-deoxytetracycline 6alpha-deoxy-5-oxytetracycline A tetracycline that has formula C22H24N2O8. C22H24N2O8 CHEBI:50845 Doxycyclin InChI=1/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1/f/h23H2 InChIKey=JBIWCJUYHHGXTC-RFTRKGKODR Jenacyclin Supracyclin Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. Vibramycin [H][C@@]12[C@@H](C)c3cccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]2O [H][C@@]12[C@@H](C)c3cccc(O)c3C(=O)C1=C(O)[C@]4(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]4([H])[C@H]2O doxiciclina doxycycline (anhydrous) doxycyclinum http://www.ebi.ac.uk/efo/EFO_0001528 antiatherogenic agent CHEBI:50855 James Malone http://www.ebi.ac.uk/efo/EFO_0001838 azinomycin B (1S)-2-{[(1E)-1-[(3R,4R,5S)-3-(acetyloxy)-4-hydroxy-1-azabicyclo[3.1.0]hex-2-ylidene]-2-{[(1Z)-1-(hydroxymethylidene)-2-oxopropyl]amino}-2-oxoethyl]amino}-1-[(2S)-2-methyloxiran-2-yl]-2-oxoethyl 3-methoxy-5-methylnaphthalene-1-carboxylate A naphthalene that has formula C31H33N3O11. C31H33N3O11 CHEBI:50862 Ele Holloway InChI=1/C31H33N3O11/c1-14-7-6-8-18-19(14)9-17(42-5)10-20(18)30(41)45-27(31(4)13-43-31)29(40)33-23(28(39)32-21(12-35)15(2)36)24-26(44-16(3)37)25(38)22-11-34(22)24/h6-10,12,22,25-27,35,38H,11,13H2,1-5H3,(H,32,39)(H,33,40)/b21-12-,24-23+/t22-,25+,26+,27+,31-,34-/m0/s1/f/h32-33H InChIKey=QIKVYJOCQXXRSJ-CKKAGOBJDQ James Malone [H][C@@]12C[N@@H]1C(\\[C@@H](OC(C)=O)[C@@H]2O)=C(\\NC(=O)[C@@H](OC(=O)c3cc(OC)cc4c(C)cccc34)[C@]5(C)CO5)C(=O)N\\C(=C/O)C(C)=O http://www.ebi.ac.uk/efo/EFO_0002005 http://www.ebi.ac.uk/efo/EFO_0002400 insulin-sensitizing drug An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma). CHEBI:50864 James Malone glitazonas glitazone drug glitazones http://www.ebi.ac.uk/efo/EFO_0001839 insulin sensitizers thiazolidinediones tiazolidinedionas 3H-1,2-dithiole-3-thione 1,2-dithiol-3-thione 1,2-dithiole-3-thione A 1,2-dithiole that has formula C3H2S3. C3H2S3 CHEBI:50866 Ele Holloway InChI=1/C3H2S3/c4-3-1-2-5-6-3/h1-2H InChIKey=LZENMJMJWQSSNJ-UHFFFAOYAS S=C1SSC=C1 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002724 ciprofibrate 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid A ring assembly that has formula C13H14Cl2O3. C13H14Cl2O3 CC(C)(Oc1ccc(cc1)C2CC2(Cl)Cl)C(O)=O CHEBI:50867 Ele Holloway InChI=1/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)/f/h16H InChIKey=KPSRODZRAIWAKH-WYUMXYHSCN James Malone ciprofibrato ciprofibratum http://www.ebi.ac.uk/efo/EFO_0002404 fludrocortisone 9-fluoro-11beta,17,21-trihydroxypregn-4-ene-3,20-dione 9ALPHA-FLUOROCORTISOL A mineralocorticoid that has formula C21H29FO5. C21H29FO5 CHEBI:50885 InChI=1/C21H29FO5/c1-18-7-5-13(24)9-12(18)3-4-15-14-6-8-20(27,17(26)11-23)19(14,2)10-16(25)21(15,18)22/h9,14-16,23,25,27H,3-8,10-11H2,1-2H3/t14-,15-,16-,18-,19-,20-,21-/m0/s1 InChIKey=AAXVEMMRQDVLJB-BULBTXNYBK [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)CC[C@]34C fludrocortisona fludrocortisonum http://www.ebi.ac.uk/efo/EFO_0001536 allergenic agent A role played by a chemical compound in the onset of allergic reaction and interacting with molecular pathways involved in allergy. CHEBI:50904 Ele Holloway James Malone alergeno allergen allergene http://www.ebi.ac.uk/efo/EFO_0002398 obsolete_antiemetic 2.23 duplicates imported class polyamide CHEBI:51953 James Malone http://www.ebi.ac.uk/efo/EFO_0002008 nilotinib 1,9-Nonanediol 1,9-Nonanediol[accessedResource: C28H22F3N7O][accessDate: 05-04-2011] 22663 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide 42663 64157-10-0 AMN 107 AMN107 An aliphatic alcohol (with nine carbon atoms and two hydroxyl groups at positions 1 and 9) used in chemical synthesis and biomedical research. 1,9-Nonanediol suppresses glycine currents in neurons; glycine is a major inhibitory neurotransmitter in the mature mammalian central nervous system. (NCI04) An aliphatic alcohol (with nine carbon atoms and two hydroxyl groups at positions 1 and 9) used in chemical synthesis and biomedical research. 1,9-Nonanediol suppresses glycine currents in neurons; glycine is a major inhibitory neurotransmitter in the mature mammalian central nervous system. (NCI04)[accessedResource: C28H22F3N7O][accessDate: 05-04-2011] An organofluorine compound that has formula C28H22F3N7O. C28H22F3N7O C28H22F3N7O Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F InChI=1/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)/f/h35,37H InChIKey=HHZIURLSWUIHRB-YESWCKIVCC nilotinibum wortmannin (1S,6bR,9aS,11R,11bR)-9a,11b-dimethyl-1-[(methyloxy)methyl]-3,6,9-trioxo-1,6,6b,7,8,9,9a,10,11,11b-decahydro-3H-furo[4,3,2-de]indeno[4,5-h]isochromen-11-yl acetate An organic heteropentacyclic compound that has formula C23H24O8. C23H24O8 CHEBI:52289 Ele Holloway InChI=1/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15+,22-,23-/m0/s1 InChIKey=QDLHCMPXEPAAMD-QAIWCSMKBP James Malone Wartmannin [H][C@@]12CCC(=O)[C@@]1(C)C[C@@H](OC(C)=O)C1=C2C(=O)c2occ3C(=O)O[C@H](COC)[C@@]1(C)c23 http://www.ebi.ac.uk/efo/EFO_0002494 bortezomib 179324-69-7 40980 C19H25BN4O4 C19H25BN4O4 CC(C)C[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O D-Phenylalaninamide substituted at the amide nitrogen by a 1-(dihydroxyboranyl)-3-methylbutyl group and at N(alpha) by a pyrazin-2-ylcarbonyl group. It is a dipeptidyl boronic acid that reversibly inhibits the 26S proteasome. Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst. Human USP6 wild-type allele is located within 17p13 and is approximately 47 kb in length. This allele, which encodes ubiquitin carboxyl-terminal hydrolase 6 protein, is involved in protein binding and the cleavage of free ubiquitin chains. The USP6 gene is overexpressed in a specific osseous neoplasm termed an aneurysmal bone cyst.[accessedResource: C19H25BN4O4][accessDate: 05-04-2011] InChI=1/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m1/s1/f/h23-24H InChIKey=GXJABQQUPOEUTA-ASWDFQEKDB N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-Nalpha-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide N-[(1S)-1-(dihydroxyboranyl)-3-methylbutyl]-N(alpha)-(pyrazin-2-ylcarbonyl)-D-phenylalaninamide PS-341 Proto-Oncogene TRE-2 Proto-Oncogene TRE-2[accessedResource: C19H25BN4O4][accessDate: 05-04-2011] TRE-2 Gene TRE-2 Gene[accessedResource: C19H25BN4O4][accessDate: 05-04-2011] USP6 wt Allele USP6 wt Allele[accessedResource: C19H25BN4O4][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele Ubiquitin Specific Protease 6 (Tre-2 Oncogene) wt Allele[accessedResource: C19H25BN4O4][accessDate: 05-04-2011] Ubiquitin Specific Protease 6 Gene Ubiquitin Specific Protease 6 Gene[accessedResource: C19H25BN4O4][accessDate: 05-04-2011] Velcade [(1S)-3-methyl-1-({(2R)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid cytochalasin D (3S,3aR,4S,6S,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate 22144-77-0 7,18-Dihydroxy-10-phenyl-5,16,18-trimethyl-(11)cytochalas-21-acetoxy-6(12),13,19-trien-17-one A mycotoxin, which is cell permeable and a potent inhibitor of actin polymerisation and DNA synthesis. C30H37NO6 Cytohalasin D InChI=1/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22?,23-,24+,25-,26+,29+,30+/m0/s1/f/h31H InChIKey=SDZRWUKZFQQKKV-YSLPTORADC Lygosporin A Zygosporin A [H][C@]12[C@H](Cc3ccccc3)NC(=O)[C@]11[C@H](OC(C)=O)\\C=C\\[C@@](C)(O)C(=O)[C@@H](C)C\\C=C\\C1[C@H](O)C(=C)[C@H]2C beta amyloid 40425 naphthalene-1,5-diamine 1,5-Diaminonaphthalene 1,5-Naphthalenediamine 1,5-Naphthylenediamine A naphthalenediamine compound having amino substituents in the 1- and 5-positions. C10H10N2 CHEBI:53003 Ele Holloway InChI=1/C10H10N2/c11-9-5-1-3-7-8(9)4-2-6-10(7)12/h1-6H,11-12H2 InChIKey=KQSABULTKYLFEV-UHFFFAOYAR James Malone Nc1cccc2c(N)cccc12 http://www.ebi.ac.uk/efo/EFO_0002492 1-fluoro-2,4-dinitrobenzene 1,2,4-Fluorodinitrobenzene 2,4-DNFB 2,4-Dinitro-1-fluorobenzene 2,4-Dinitrobenzenefluoride 2,4-Dinitrofluorobenzene 2,4-Dinitrophenyl fluoride A fluorobenzene compound with two nitro substituents in the 2- and 4-positions. C6H3FN2O4 CHEBI:53049 DFB DNFB Dinitrofluorobenzene Ele Holloway FDNB Fluoro-2,4-dinitrobenzene Fluorodinitrobenzene InChI=1/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H InChIKey=LOTKRQAVGJMPNV-UHFFFAOYAZ Tomasz Adamusiak [O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O http://www.ebi.ac.uk/efo/EFO_0002722 Bandrowski's base 20048-27-5 24031 44031 A quinone imine compound having amino substituents in the 2- and 5-positions and 4-aminophenyl substituents on both of the imine nitrogens. BB C18H18N6 C18H18N6 EFABP EFABP[accessedResource: C18H18N6][accessDate: 05-04-2011] Epidermal Fatty Acid-Binding Protein Epidermal Fatty Acid-Binding Protein[accessedResource: C18H18N6][accessDate: 05-04-2011] Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI) Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI)[accessedResource: C18H18N6][accessDate: 05-04-2011] FABP5 FABP5[accessedResource: C18H18N6][accessDate: 05-04-2011] Fatty Acid Binding Protein 5 Fatty Acid Binding Protein 5[accessedResource: C18H18N6][accessDate: 05-04-2011] InChI=1/C18H18N6/c19-11-1-5-13(6-2-11)23-17-9-16(22)18(10-15(17)21)24-14-7-3-12(20)4-8-14/h1-10H,19-22H2/b23-17+,24-18+ InChIKey=KKJZEUXMWDXPAU-GJHDBBOXBG N(1),N(1)'-(2,5-diaminocyclohexa-2,5-diene-1,4-diylidene)dibenzene-1,4-diamine N1,N1'-(2,5-diaminocyclohexa-2,5-diene-1,4-diylidene)dibenzene-1,4-diamine Nc1ccc(cc1)\\N=C1/C=C(N)\\C(\\C=C/1N)=N\\c1ccc(N)cc1 PAFABP PAFABP[accessedResource: C18H18N6][accessDate: 05-04-2011] 4,5-dianilinophthalimide 5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione C20H15N3O2 CHEBI:53110 Cgp 52411 DAPH DAPH1 Ele Holloway InChI=1/C20H15N3O2/c24-19-15-11-17(21-13-7-3-1-4-8-13)18(12-16(15)20(25)23-19)22-14-9-5-2-6-10-14/h1-12,21-22H,(H,23,24,25)/f/h23H InChIKey=AAALVYBICLMAMA-MPIMZMORCI James Malone O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12 Phthalimide substituted at the 4- and 5-positions by anilino groups. http://www.ebi.ac.uk/efo/EFO_0002487 8-(3-chlorostyryl) caffeine 1,3,7-trimethyl-8-(3-chlorostyryl)xanthine 8-(3-chlorostyryl)caffeine 8-CSC 8-[(E)-2-(3-chlorophenyl)ethenyl]-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione C16H15ClN4O2 CHEBI:53115 CSC Caffeine substituted at its 8-position by an (E)-3-chlorostyryl group. Cn1c(\\C=C\\c2cccc(Cl)c2)nc2n(C)c(=O)n(C)c(=O)c12 Ele Holloway InChI=1/C16H15ClN4O2/c1-19-12(8-7-10-5-4-6-11(17)9-10)18-14-13(19)15(22)21(3)16(23)20(14)2/h4-9H,1-3H3/b8-7+ InChIKey=WBWFIUAVMCNYPG-BQYQJAHWBU James Malone http://www.ebi.ac.uk/efo/EFO_0002490 polysorbate 20 A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 and a single terminal is capped by a dodecanoyl group. InChI=1/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3 InChIKey=HMFKFHLTUCJZJO-UHFFFAOYAO Polyoxyethylene (20) sorbitan monolaurate Polyoxyethylene sorbitan monolaurate Polysorbate Tween 20 calcineurin CHEBI:53439 Ele Holloway Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002734 potassium dichromate 25948 5948 7778-50-9 Chromium potassium oxide Cr2K2O7 Cr2K2O7 Dichromic acid dipotassium salt Dipotassium bichromate Dipotassium dichromium heptaoxide InChI=1/2Cr.2K.7O/q;;2*+1;;;;;;2*-1 InChIKey=KMUONIBRACKNSN-UHFFFAOYAS Kaliumdichromat Potassium dichromate The dipotassium salt of dichromic acid. [K+].[K+].[O-][Cr](=O)(=O)O[Cr]([O-])(=O)=O dipotassium dichromate potassium dichromate(2-) potassium dichromate(VI) methyl cellulose (C9H16O5)n A (1->4)-beta-D-glucan compound formed by methylating cellulose through exposure to NaOH/CH3Cl. CHEBI:53448 Cellulose methylate E461 Ele Holloway InChI=1/C29H54O16/c1-30-12-15-18(33-4)21(34-5)25(38-9)28(42-15)45-20-17(14-32-3)43-29(26(39-10)23(20)36-7)44-19-16(13-31-2)41-27(40-11)24(37-8)22(19)35-6/h15-29H,12-14H2,1-11H3/t15-,16-,17-,18-,19-,20-,21+,22+,23+,24-,25-,26-,27-,28+,29+/m1/s1 InChIKey=LNAZSHAWQACDHT-XIYTZBAFBM Methylcellulosum Metilcelulosa Tomasz Adamusiak cellulose methyl ether http://www.ebi.ac.uk/efo/EFO_0002735 methylated cellulose methylcellulose N-(1-naphthyl)ethylenediamine dihydrochloride An ethylenediamine dihydrochloride compound having an N-(1-naphthyl) substituent. C12H16Cl2N2 CHEBI:53452 Ele Holloway InChI=1/C12H14N2.2ClH/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12;;/h1-7,14H,8-9,13H2;2*1H/fC12H16N2.2Cl/h13-14H;2*1h/q+2;2*-1 InChIKey=MZNYWPRCVDMOJG-PEHGYZQZCO Marshall's reagent N-(1-Naphthyl)ethylenediamine.2HCl N-(1-Napthyl)ethylene diamine HCl N-(1-Napthyl)ethylene diamine dihydrochloride N-(1-naphthyl)ethane-1,2-diaminium dichloride N-1-Naphthalenyl-1,2-ethanediamine dihydrochloride Tomasz Adamusiak [Cl-].[Cl-].[NH3+]CC[NH2+]c1cccc2ccccc12 http://www.ebi.ac.uk/efo/EFO_0002736 neuropeptide S CHEBI:53461 Ele Holloway Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002737 nickel(II) chloride hexahydrate 21170 41170 7791-20-0 A hydrate of nickel chloride containing nickel (in the +2 oxidation state), chloride and water moeities in the ratio 1:2:6. Cl2H12NiO6 H12Cl2NiO6 InChI=1/2ClH.Ni.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2/f2Cl.Ni.6H2O/h2*1h;;;;;;;/q2*-1;m;;;;;; InChIKey=LAIZPRYFQUWUBN-GPHKFXFTCI Nickel dichloride hexahydrate O.O.O.O.O.O.[Cl-].[Cl-].[Ni++] dichloronickel hexahydrate nickel chloride hexahydrate nickel chloride--water (1/6) glucosamine 2-amino-2-deoxyglucose C6H13NO5 CHEBI:5417 GlcN Glucosamin Glukosamin http://www.ebi.ac.uk/efo/EFO_0001544 radicicol (1aR,2Z,4E,14R,15aR)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione (2Z,4E)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione 12772-57-5 22692 42692 An antifungal macrolactone antibiotic, obtained from Diheterospora chlamydosporia, that inhibits protein tyrosine kinase. C18H17ClO6 C18H17ClO6 C[C@@H]1C[C@H]2O[C@@H]2\\C=C/C=C/C(=O)Cc2c(Cl)c(O)cc(O)c2C(=O)O1 EFABP EFABP[accessedResource: C18H17ClO6][accessDate: 05-04-2011] Epidermal Fatty Acid-Binding Protein Epidermal Fatty Acid-Binding Protein[accessedResource: C18H17ClO6][accessDate: 05-04-2011] Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI) Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI)[accessedResource: C18H17ClO6][accessDate: 05-04-2011] FABP5 FABP5[accessedResource: C18H17ClO6][accessDate: 05-04-2011] Fatty Acid Binding Protein 5 Fatty Acid Binding Protein 5[accessedResource: C18H17ClO6][accessDate: 05-04-2011] InChI=1/C18H17ClO6/c1-9-6-15-14(25-15)5-3-2-4-10(20)7-11-16(18(23)24-9)12(21)8-13(22)17(11)19/h2-5,8-9,14-15,21-22H,6-7H2,1H3/b4-2+,5-3-/t9-,14-,15-/m1/s1 InChIKey=WYZWZEOGROVVHK-GTMNPGAYBX Monorden PAFABP PAFABP[accessedResource: C18H17ClO6][accessDate: 05-04-2011] haloperidol 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine 4'-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone 4'-fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone 4-(4-(para-chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4; and an N-linked p-fluorobutyrophenone moiety. A hydroxypiperidine that has formula C21H23ClFNO2. C21H23ClFNO2 CHEBI:5613 Haldol InChI=1/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 InChIKey=LNEPOXFFQSENCJ-UHFFFAOYAL OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 gamma-(4-(p-chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone haloperidolum http://www.ebi.ac.uk/efo/EFO_0001549 halothane 1,1,1-trifluoro-2-bromo-2-chloroethane 1,1,1-trifluoro-2-chloro-2-bromoethane 1-bromo-1-chloro-2,2,2-trifluoroethane 2,2,2-trifluoro-1-chloro-1-bromoethane 2-bromo-2-chloro-1,1,1-trifluoroethane A haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position. A haloalkane that has formula C2HBrClF3. C2HBrClF3 CHEBI:5615 Fluothane InChI=1/C2HBrClF3/c3-1(4)2(5,6)7/h1H InChIKey=BCQZXOMGPXTTIC-UHFFFAOYAO James Malone Narcotane Phthorothanum Rhodialothan [H]C(Cl)(Br)C(F)(F)F bromochlorotrifluoroethane http://www.ebi.ac.uk/efo/EFO_0001550 hexachlorobenzene 1,2,3,4,5,6-hexachlorobenzene 118-74-1 20682 682 A chlorobenzene that has formula C6Cl6. C6 Vertebra C6 Vertebra[accessedResource: C6Cl6][accessDate: 05-04-2011] C6Cl6 C6Cl6 Clc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl HCB Hexachlorbenzol InChI=1/C6Cl6/c7-1-2(8)4(10)6(12)5(11)3(1)9 InChIKey=CKAPSXZOOQJIBF-UHFFFAOYAV The sixth of the seven cervical vertebrae. The sixth of the seven cervical vertebrae.[accessedResource: C6Cl6][accessDate: 05-04-2011] hexachlorobenzene perchlorobenzene phenyl perchloryl caerulein 17650-98-5 40434 5-oxo-L-prolyl-L-glutaminyl-L-a-aspartyl-O-sulfo-L-tyrosyl-L-threonylglycyl-L-tryptophyl-L-methionyl-L-a-aspartyl-L-phenylalaninamide 5-oxo-L-prolyl-L-glutaminyl-L-alpha-aspartyl-O-sulfo-L-tyrosyl-L-threonylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction. C58 C58 Mouse C58 Mouse[accessedResource: C58H73N13O21S2][accessDate: 05-04-2011] C58H73N13O21S2 C58H73N13O21S2 C58[accessedResource: C58H73N13O21S2][accessDate: 05-04-2011] InChI=1/C58H73N13O21S2/c1-29(72)49(71-57(87)40(23-31-12-14-33(15-13-31)92-94(89,90)91)68-56(86)43(26-48(78)79)69-52(82)37(16-18-44(59)73)65-51(81)36-17-19-45(74)63-36)58(88)62-28-46(75)64-41(24-32-27-61-35-11-7-6-10-34(32)35)54(84)66-38(20-21-93-2)53(83)70-42(25-47(76)77)55(85)67-39(50(60)80)22-30-8-4-3-5-9-30/h3-15,27,29,36-43,49,61,72H,16-26,28H2,1-2H3,(H2,59,73)(H2,60,80)(H,62,88)(H,63,74)(H,64,75)(H,65,81)(H,66,84)(H,67,85)(H,68,86)(H,69,82)(H,70,83)(H,71,87)(H,76,77)(H,78,79)(H,89,90,91)/t29-,36+,37+,38+,39+,40+,41+,42+,43+,49+/m1/s1/f/h62-71,76,78,89H,59-60H2 InChIKey=YRALAIOMGQZKOW-IMKAHHCODB [H][C@](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCC(=O)N1)([C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O cerulein ceruletida ceruletide ceruletidum insulin CHEBI:5931 James Malone MSH:D007328 http://www.ebi.ac.uk/efo/EFO_0001673 true cyproheptadine hydrochloride 22586 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride 4-(5H-dibenzo[a,d]cyclohepten-5-ylidine)-methylpiperidine hydrochloride 42586 969-33-5 C21 C21H22ClN C21H22ClN C21[accessedResource: C21H22ClN][accessDate: 05-04-2011] Cl.CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12 DC42 DC42[accessedResource: C21H22ClN][accessDate: 05-04-2011] FLJ12894 FLJ12894[accessedResource: C21H22ClN][accessDate: 05-04-2011] Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia. Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia.[accessedResource: C21H22ClN][accessDate: 05-04-2011] IRA1 IRA1[accessedResource: C21H22ClN][accessDate: 05-04-2011] InChI=1/C21H21N.ClH/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21;/h2-11H,12-15H2,1H3;1H InChIKey=ZPMVNZLARAEGHB-UHFFFAOYAU TBL1XR1 wt Allele TBL1XR1 wt Allele[accessedResource: C21H22ClN][accessDate: 05-04-2011] TBLR1 TBLR1[accessedResource: C21H22ClN][accessDate: 05-04-2011] The hydrochloride salt of cyproheptadine. Note that the drug named cyproheptadine hydrochloride generally refers to cyproheptadine hydrochloride sesquihydrate. Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele[accessedResource: C21H22ClN][accessDate: 05-04-2011] Transducin (Beta)-Like 1X-Linked Receptor 1 Gene Transducin (Beta)-Like 1X-Linked Receptor 1 Gene[accessedResource: C21H22ClN][accessDate: 05-04-2011] anhydraous cyproheptadine hydrochloride cyproheptadine HCl cyproheptadine hydrochloride (anh.) cyproheptadine hydrochloride (anhydrous) isoflurane 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether 2-chloro-2-difluoromethoxy-1,1,1-trifluoroethane Aerrane An organofluorine compound that has formula C3H2ClF5O. C3H2ClF5O CHEBI:6015 Ethane FC(F)OC(Cl)C(F)(F)F Forane Forene InChI=1/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H InChIKey=PIWKPBJCKXDKJR-UHFFFAOYAP James Malone http://www.ebi.ac.uk/efo/EFO_0001559 isoflurano isofluranum isotretinoin (2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid (7E,9E,11E,13Z)-retinoic acid 13-RA 13-cis-Vitamin A acid 13-cis-retinoic acid A retinoic acid that has formula C20H28O2. Accutane Amnesteem C20H28O2 CC1=C(\\C=C\\C(C)=C\\C=C\\C(C)=C/C(O)=O)C(C)(C)CCC1 CHEBI:6067 Claravis Ele Holloway InChI=1/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-/f/h21H InChIKey=SHGAZHPCJJPHSC-WWZGNHTLDJ James Malone Neovitamin A acid http://www.ebi.ac.uk/efo/EFO_0002411 isotretinoine isotretinoino isotretinoinum lipoxin A4 (5S,6R,7E,9E,11Z,13E,15S)-5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid 5S,6R,15S-Trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid 5S,6R-LipoxinA4 A lipoxin that has formula C20H32O5. C20H32O5 CCCCC[C@H](O)\\C=C\\C=C/C=C/C=C/[C@@H](O)[C@@H](O)CCCC(O)=O InChI=1/C20H32O5/c1-2-3-8-12-17(21)13-9-6-4-5-7-10-14-18(22)19(23)15-11-16-20(24)25/h4-7,9-10,13-14,17-19,21-23H,2-3,8,11-12,15-16H2,1H3,(H,24,25)/b6-4-,7-5+,13-9+,14-10+/t17-,18+,19-/m0/s1/f/h24H InChIKey=IXAQOQZEOGMIQS-RKIRPOAEDD LXA4 NIFSTD:nifext_5168 Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0001565 losartan (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol 114798-26-4 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole 23227 3227 A biphenylyltetrazole that has formula C22H23ClN6O. A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration. A monounsaturated very long-chain fatty acid with a 22-carbon backbone and a single double bond originating from the 9th position from the methyl end, with the double bond in the trans- configuration.[accessedResource: C22H23ClN6O][accessDate: 05-04-2011] Brassidic Acid Brassidic Acid[accessedResource: C22H23ClN6O][accessDate: 05-04-2011] C22:1, n-9 trans C22:1, n-9 trans[accessedResource: C22H23ClN6O][accessDate: 05-04-2011] C22H23ClN6O C22H23ClN6O CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Fatty Acid 22:1 n-9 trans Fatty Acid 22:1 n-9 trans[accessedResource: C22H23ClN6O][accessDate: 05-04-2011] Fatty Acid trans 22:1 n-9 Fatty Acid trans 22:1 n-9[accessedResource: C22H23ClN6O][accessDate: 05-04-2011] InChI=1/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)/f/h25H InChIKey=PSIFNNKUMBGKDQ-LNNLXFCOCF Trans docos-13-enoic Acid Trans docos-13-enoic Acid[accessedResource: C22H23ClN6O][accessDate: 05-04-2011] mesalamine 3-carboxy-4-hydroxyaniline 5-ASA 5-Aminosalicylic acid 5-amino-2-hydroxybenzoic acid An aromatic amine that has formula C7H7NO3. Asacol Asacolitin C7H7NO3 CHEBI:6775 Canasa Claversal Fisalamine Iialda InChI=1/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)/f/h10H InChIKey=KBOPZPXVLCULAV-KZFATGLACE Lixacol Mesalazina Mesalazine Mesalazinum Mesasal Nc1ccc(O)c(c1)C(O)=O Pentasa Rowasa Salofalk http://www.ebi.ac.uk/efo/EFO_0001569 m-Aminosalicylic acid p-Aminosalicylsaeure metformin 1,1-Dimethylbiguanide A guanidine that has formula C4H11N5. C4H11N5 CHEBI:6801 CN(C)C(=N)NC(N)=N InChI=1/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)/f/h5,7-8H,6H2 InChIKey=XZWYZXLIPXDOLR-WXQAPKLBCT N,N-dimethylimidodicarbonimidic diamide http://www.ebi.ac.uk/efo/EFO_0001570 methamphetamine (+)-(S)-N-alpha-dimethylphenethylamine (2S)-N-methyl-1-phenylpropan-2-amine (S)-N,alpha-dimethylbenzeneethanamine (alphaS)-N,alpha-dimethylbenzeneethanamine An amphetamine that has formula C10H15N. C10H15N CHEBI:6809 CN[C@@H](C)Cc1ccccc1 InChI=1/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1 InChIKey=MYWUZJCMWCOHBA-VIFPVBQEBN d-1-phenyl-2-methylaminopropane d-N-methylamphetamine d-deoxyephedrine d-desoxyephedrine d-phenylisopropylmethylamine http://www.ebi.ac.uk/efo/EFO_0001571 methyl-beta-phenylisopropylamine methapyrilene 2-[[2-(dimethylamino)ethyl]-2-thenylamino]pyridine 23278 3278 91-80-5 A radiolabelled urea molecule used to diagnose stomach ulcers caused by Heliobacter pylori. In the presence of H. pylori, urea C-14 is metabolized by urease to produce ammonia and radioactive carbon dioxide at the interface between the gastric epithelium and lumen. The radioactive carbon dioxide is absorbed in the blood and is detected when exhaled in the breath. A radiolabelled urea molecule used to diagnose stomach ulcers caused by Heliobacter pylori. In the presence of H. pylori, urea C-14 is metabolized by urease to produce ammonia and radioactive carbon dioxide at the interface between the gastric epithelium and lumen. The radioactive carbon dioxide is absorbed in the blood and is detected when exhaled in the breath.[accessedResource: C14H19N3S][accessDate: 05-04-2011] An ethylenediamine derivative that has formula C14H19N3S. C14 Urea C14 Urea[accessedResource: C14H19N3S][accessDate: 05-04-2011] C14H19N3S C14H19N3S CN(C)CCN(Cc1cccs1)c1ccccn1 Histadyl InChI=1/C14H19N3S/c1-16(2)9-10-17(12-13-6-5-11-18-13)14-7-3-4-8-15-14/h3-8,11H,9-10,12H2,1-2H3 InChIKey=HNJJXZKZRAWDPF-UHFFFAOYAC Lullamin N,N-dimethyl-N'-pyrid-2-yl-N'-2-thenylethylenediamine N,N-dimethyl-N'-pyridin-2-yl-N'-(2-thienylmethyl)ethane-1,2-diamine N,N-dimethyl-N'-pyridin-2-yl-N'-(2-thienylmethyl)ethane-1,2-diamine N,N-dimethyl-N'-pyridin-2-yl-N'-[(thiophen-2-yl)methyl]ethane-1,2-diamine N-(alpha-pyridyl)-N-(alpha-thenyl)-N',N'-dimethylethylenediamine Pyrathyn Pytest Pytest[accessedResource: C14H19N3S][accessDate: 05-04-2011] UREA, C-14 UREA, C-14[accessedResource: C14H19N3S][accessDate: 05-04-2011] Urea C-14 Urea C-14[accessedResource: C14H19N3S][accessDate: 05-04-2011] methypyrilene thenylpyramine methoxychlor 1,1'-(2,2,2-trichloroethane-1,1-diyl)bis(4-methoxybenzene) 1,1'-(2,2,2-trichloroethane-1,1-diyl)bis[4-(methyloxy)benzene] 1,1,1-trichloro-2,2-bis(p-anisyl)ethane 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)ethane 1,1,1-trichloro-2,2-di(4-methoxyphenyl)ethane 2,2-bis(p-anisyl)-1,1,1-trichloroethane 2,2-bis(p-methoxyphenyl)-1,1,1-trichloroethane 2,2-di(p-methoxyphenyl)-1,1,1-trichloroethane 20827 4A's Treatment Protocol 4As Treatment Protocol 4As Treatment Strategy 72-43-5 827 A smoking cessation strategy recommended by the National Cancer Institute. The first 'A' is to ask patients about their smoking status at every visit and record this information. The second 'A' is to advise smokers to quit. The third 'A' is to assist patients' cessation attempts where possible by helping them to set a quit date, providing self-help materials, prescribing pharmacological treatment, and recommending counseling. The final 'A' is to arrange follow-up contact. (from Medscape) Acoustic Acoustic[accessedResource: C16H15Cl3O2][accessDate: 05-04-2011] An organochlorine insecticide that has formula C16H15Cl3O2. C16H15Cl3O2 C16H15Cl3O2 COc1ccc(cc1)C(c1ccc(OC)cc1)C(Cl)(Cl)Cl InChI=1/C16H15Cl3O2/c1-20-13-7-3-11(4-8-13)15(16(17,18)19)12-5-9-14(21-2)10-6-12/h3-10,15H,1-2H3 InChIKey=IAKOZHOLGAGEJT-UHFFFAOYAO dimethoxy-DDT methoxy-DDT p,p'-methoxychlor 6alpha-methylprednisolone (6alpha,11beta)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione 1-dehydro-6alpha-methylhydrocortisone 11beta,17,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione A 6-methylprednisolone that has formula C22H30O5. C22H30O5 CHEBI:6888 Delta(1)-6alpha-methylhydrocortisone InChI=1/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1 InChIKey=VHRSUDSXCMQTMA-PJHHCJLFBP James Malone Medrate Medrol Medrone Methylprednisolon Solomet Urbason [H][C@@]12C[C@H](C)C3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO http://www.ebi.ac.uk/efo/EFO_0001475 methylprednisolone methylprednisolonum metilprednisolona metoprolol (H115D)VHL35 (H115D)VHL35 Peptide (RS)-Metoprolol 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol 1-[(1-methylethyl)amino]-3-({4-[2-(methyloxy)ethyl]phenyl}oxy)propan-2-ol 23309 3-[4-(2-methoxyethyl)phenoxy]-1-(propan-2-ylamino)propan-2-ol 3309 51384-51-1 A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation. (NCI04) A propanolamine that has formula C15H25NO3. C15H25NO3 C15H25NO3 C15[accessedResource: C15H25NO3][accessDate: 05-04-2011] COCCc1ccc(OCC(O)CNC(C)C)cc1 Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse. Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse.[accessedResource: C15H25NO3][accessDate: 05-04-2011] InChI=1/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3 InChIKey=IUBSYMUCCVWXPE-UHFFFAOYAN Onzin Onzin[accessedResource: C15H25NO3][accessDate: 05-04-2011] PLAC8 wt Allele PLAC8 wt Allele[accessedResource: C15H25NO3][accessDate: 05-04-2011] Placenta-Specific 8 wt Allele Placenta-Specific 8 wt Allele[accessedResource: C15H25NO3][accessDate: 05-04-2011] miconazole 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole 1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole 22916-47-8 23319 An imidazole antifungal agent, commonly applied topically (to the skin) or mucus membranes to cure fungal infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes. C18H14Cl4N2O Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 Daktarin IV EFABP EFABP[accessedResource: C18H14Cl4N2O][accessDate: 05-04-2011] Epidermal Fatty Acid-Binding Protein Epidermal Fatty Acid-Binding Protein[accessedResource: C18H14Cl4N2O][accessDate: 05-04-2011] Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI) Expressed in keratinocytes by human FABP5 Gene (FABP Family), highly conserved 135-aa 15-kDa cytoplasmic Fatty Acid Binding Protein 5 binds long-chain fatty acids with high specificity, and other hydrophobic ligands. Likely involved in fatty acid uptake, transport, or metabolism and in keratinocyte differentiation, FABP5 has highest affinity for C18 chain lengths and decreasing affinity for decreasing chain lengths or chains with double bonds. (NCI)[accessedResource: C18H14Cl4N2O][accessDate: 05-04-2011] FABP5 FABP5[accessedResource: C18H14Cl4N2O][accessDate: 05-04-2011] Fatty Acid Binding Protein 5 Fatty Acid Binding Protein 5[accessedResource: C18H14Cl4N2O][accessDate: 05-04-2011] InChI=1/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2 InChIKey=BYBLEWFAAKGYCD-UHFFFAOYAA Monistat IV (TN) PAFABP PAFABP[accessedResource: C18H14Cl4N2O][accessDate: 05-04-2011] N-methylformamide A formamide compound having an N-methyl substituent. C2H5NO CHEBI:7438 Ele Holloway HCONHCH3 InChI=1/C2H5NO/c1-3-2-4/h2H,1H3,(H,3,4)/f/h3H InChIKey=ATHHXGZTWNVVOU-TULZNQERCH Methylformamide Monomethylformamide N-Methyl-formamide N-Monomethylformamide NMF Tomasz Adamusiak [H]C(=O)NC http://www.ebi.ac.uk/efo/EFO_0002732 nandrolone (17beta)-17-hydroxyestr-4-en-3-one 17beta-hydroxy-19-nor-4-androsten-3-one 17beta-hydroxy-4-estren-3-one 17beta-hydroxyestr-4-en-3-one 19-Norandrostenolone 19-Nortestosterone 4-estren-17beta-ol-3-one 434-22-0 InChI=1/C18H26O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-17,20H,2-9H2,1H3/t13-,14+,15+,16-,17-,18-/m0/s1 InChIKey=NPAGDVCDWIYMMC-IZPLOLCNBQ [H][C@]12CCC(=O)C=C1CC[C@]1([H])[C@]2([H])CC[C@]2(C)[C@@H](O)CC[C@@]12[H] nifedipine 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester A dihydropyridine that has formula C17H18N2O6. Adalat Adapine C17H18N2O6 CHEBI:7565 COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC Coracten InChI=1/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3 InChIKey=HYIMSNHJOBLJNT-UHFFFAOYAE Nifecard Nifecor Nifedipres Procardia dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate http://www.ebi.ac.uk/efo/EFO_0001578 nifedipino nifedipinum ochratoxin A (-)-N-((5-chloro-8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenylalanine (R)-N-((5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl)phenylalanine A phenylalanine derivative that has formula C20H18ClNO6. C20H18ClNO6 CHEBI:7719 C[C@@H]1Cc2c(Cl)cc(C(=O)N[C@@H](Cc3ccccc3)C(O)=O)c(O)c2C(=O)O1 C[C@@H]1Cc2c(Cl)cc(cc2C(=O)O1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1/C20H18ClNO5/c1-11-7-14-15(20(26)27-11)9-13(10-16(14)21)18(23)22-17(19(24)25)8-12-5-3-2-4-6-12/h2-6,9-11,17H,7-8H2,1H3,(H,22,23)(H,24,25)/t11-,17+/m1/s1/f/h22,24H InChI=1/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1/f/h22,25H InChIKey=RWQKHEORZBHNRI-RKENYTOSDR InChIKey=SXHXNWAJMDYKPB-CEHVPASVDA James Malone N-(((3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenyl-L-alanine N-{[(3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-yl]carbonyl}-L-phenylalanine http://www.ebi.ac.uk/efo/EFO_0001584 olanzapine 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine A benzodiazepine that has formula C17H20N4S. C17H20N4S CN1CCN(CC1)C2=Nc3ccccc3Nc4sc(C)cc24 InChI=1/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 InChIKey=KVWDHTXUZHCGIO-UHFFFAOYAQ James Malone Zyprexa olanzapina olanzapinum oseltamivir 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha,4beta,5alpha))- 196618-13-0 A cyclohexenecarboxylate ester that has formula C16H28N2O4. Agucort C16H28N2O4 CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1 Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate GS-4104 HSDB 7433 InChI=1/C16H28N2O4/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19/h9,12-15H,5-8,17H2,1-4H3,(H,18,19)/t13-,14+,15+/m0/s1/f/h18H InChIKey=VSZGPKBBMSAYNT-HRPFSUSRDU ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate oseltamivirum oxazepam (H115D)VHL35 (H115D)VHL35 Peptide (RS)-Oxazepam 1087 21087 604-75-1 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one A 1,4-benzodiazepinone that has formula C15H11ClN2O2. A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation. (NCI04) C15H11ClN2O2 C15H11ClN2O2 C15[accessedResource: C15H11ClN2O2][accessDate: 05-04-2011] Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse. Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse.[accessedResource: C15H11ClN2O2][accessDate: 05-04-2011] InChI=1/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)/f/h17H InChIKey=ADIMAYPTOBDMTL-HCKMINDGCL OC1N=C(c2ccccc2)c2cc(Cl)ccc2NC1=O Onzin Onzin[accessedResource: C15H11ClN2O2][accessDate: 05-04-2011] PLAC8 wt Allele PLAC8 wt Allele[accessedResource: C15H11ClN2O2][accessDate: 05-04-2011] Placenta-Specific 8 wt Allele Placenta-Specific 8 wt Allele[accessedResource: C15H11ClN2O2][accessDate: 05-04-2011] Serax Tazepam parthenolide (1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one (1aR,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one (H115D)VHL35 (H115D)VHL35 Peptide 20554-84-1 4,5-alpha-Epoxy-6-beta-hydroxygermacra-1(10),11(13)-dien-12-oic acid gamma-lactone 40579 A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation. (NCI04) A sesquiterpene lactone and active principle of feverfew. C15H20O3 C15H20O3 C15[accessedResource: C15H20O3][accessDate: 05-04-2011] Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse. Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse.[accessedResource: C15H20O3][accessDate: 05-04-2011] InChI=1/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11-,12-,13+,15+/m0/s1 InChIKey=KTEXNACQROZXEV-PVLRGYAZBM Onzin Onzin[accessedResource: C15H20O3][accessDate: 05-04-2011] PLAC8 wt Allele PLAC8 wt Allele[accessedResource: C15H20O3][accessDate: 05-04-2011] Placenta-Specific 8 wt Allele Placenta-Specific 8 wt Allele[accessedResource: C15H20O3][accessDate: 05-04-2011] [H][C@@]12CC\\C(C)=C\\CC[C@@]3(C)O[C@]3([H])[C@@]1([H])OC(=O)C2=C D-penicillamine (-)-penicillamine (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid (S)-2-amino-3-mercapto-3-methylbutanoic acid (S)-3,3-dimethylcysteine 3-mercapto-D-valine 3-sulfanyl-D-valine A trisubstituted carboxylic acid with amino, methyl and sulfanyl substituents. Pharmaceutical form (L-form is toxic) of chelating agent used to treat heavy metal poisoning. An optically active form of penicillamine having D-configuration. Pharmaceutical form (L-form is toxic) of chelating agent used to treat heavy metal poisoning. C5H11NO2S CC(C)(S)[C@@H](N)C(O)=O CHEBI:7959 Cuprimine D-Penamine D-beta,beta-dimethylcysteine Depen Ele Holloway InChI=1/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1/f/h7H InChIKey=VVNCNSJFMMFHPL-GFBCBKCJDA PA Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002726 penicilamina penicillaminum phenobarbital 5-Ethyl-5-phenyl-pyrimidine-2,4,6-trione 5-Ethyl-5-phenylbarbituric acid 5-Phenyl-5-ethylbarbituric acid 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione 5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione A barbiturate that has formula C12H12N2O3. Barbituric acid substituted at C-5 by ethyl and phenyl groups. C12H12N2O3 CCC1(C(=O)NC(=O)NC1=O)c1ccccc1 CHEBI:8069 InChI=1/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-7H,2H2,1H3,(H2,13,14,15,16,17)/f/h13-14H InChIKey=DDBREPKUVSBGFI-KGCNKATMCV James Malone Luminal PHENYLETHYLMALONYLUREA Phenobarbitol Phenobarbitone Phenobarbituric Acid Phenylaethylbarbitursaeure Phenylethylbarbiturate Phenylethylbarbituric Acid Phenylethylbarbitursaeure http://www.ebi.ac.uk/efo/EFO_0001591 phenylephrine (-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol 10-Deacetyltaxol 23465 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol 3465 59-42-7 A series of reactions that result in formation of a pore, composed of complement proteins C5b, C6, C7, C8, and C9, in the membrane of a pathogenic cell. The pore allows free diffusion of molecules into and out of the cell and reduces cell viability. A series of reactions that result in formation of a pore, composed of complement proteins C5b, C6, C7, C8, and C9, in the membrane of a pathogenic cell. The pore allows free diffusion of molecules into and out of the cell and reduces cell viability.[accessedResource: C9H13NO2][accessDate: 05-04-2011] Activation of Membrane Attack Complex Activation of Membrane Attack Complex[accessedResource: C9H13NO2][accessDate: 05-04-2011] An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis. Benzenemethanol, 3-hydroxy-.alpha.-[(methylamino)methyl]-, (R)- Benzyl alcohol, m-hydroxy-alpha-((methylamino)methyl)-, (-)- C9H13NO2 CNC[C@H](O)c1cccc(O)c1 InChI=1/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1 InChIKey=SONNWYBIRXJNDC-VIFPVBQEBB R(-)-Phenylephrine benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))- fenilefrina l-(3-Hydroxyphenyl)-N-methylethanolamine phenylephrinum pimozide 1,9-Nonanediol 1,9-Nonanediol[accessedResource: C28H29F2N3O][accessDate: 05-04-2011] 1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one 1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one 2062-78-4 23474 A heteroarylpiperidine that has formula C28H29F2N3O. An aliphatic alcohol (with nine carbon atoms and two hydroxyl groups at positions 1 and 9) used in chemical synthesis and biomedical research. 1,9-Nonanediol suppresses glycine currents in neurons; glycine is a major inhibitory neurotransmitter in the mature mammalian central nervous system. (NCI04) An aliphatic alcohol (with nine carbon atoms and two hydroxyl groups at positions 1 and 9) used in chemical synthesis and biomedical research. 1,9-Nonanediol suppresses glycine currents in neurons; glycine is a major inhibitory neurotransmitter in the mature mammalian central nervous system. (NCI04)[accessedResource: C28H29F2N3O][accessDate: 05-04-2011] C28H29F2N3O C28H29F2N3O Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 Halomonth InChI=1/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)/f/h31H InChIKey=YVUQSNJEYSNKRX-VJSLDGLSCK Neoperidole Opiran Orap pimozida pimozidum pioglitazone (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione A thiazolidenedione that has formula C19H20N2O3S. C19H20N2O3S CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1 CHEBI:8228 InChI=1/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)/f/h21H InChIKey=HYAFETHFCAUJAY-PKSOQXRJCR James Malone http://www.ebi.ac.uk/efo/EFO_0001592 pioglitazona pioglitazonum prednisolone (11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione 1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 3,20-dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene A glucocorticoid that has formula C21H28O5. C21H28O5 CHEBI:8378 Delta(1)-dehydrocortisol Delta(1)-dehydrohydrocortisone Delta(1)-hydrocortisone InChI=1/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 InChIKey=OIGNJSKKLXVSLS-VWUMJDOOBF [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO http://www.ebi.ac.uk/efo/EFO_0001595 hydroretrocortine metacortandralone prochlorperazine 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine 3-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine A N-methylpiperazine that has formula C20H24ClN3S. A phenothiazine derivative having a chloro subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. C20H24ClN3S CHEBI:8435 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine InChI=1/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 InChIKey=WIKYUJGCLQQFNW-UHFFFAOYAF James Malone N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine Prochlorperazin Prochlorpermazine Prochlorpromazine Procloperazine http://www.ebi.ac.uk/efo/EFO_0001597 prochlorperazinum proclorperazina 6-propyl-2-thiouracil 1209 2,3-dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone 21209 4-propyl-2-thiouracil 51-52-5 6-propyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one 6-propyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 6-propyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one C7 C7H10N2OS C7H10N2OS C7[accessedResource: C7H10N2OS][accessDate: 05-04-2011] CCCc1cc(=O)[nH]c(=S)[nH]1 CRG-2 CRG-2[accessedResource: C7H10N2OS][accessDate: 05-04-2011] CXCL10 wt Allele CXCL10 wt Allele[accessedResource: C7H10N2OS][accessDate: 05-04-2011] Chemokine (C-X-C Motif) Ligand 10 wt Allele Chemokine (C-X-C Motif) Ligand 10 wt Allele[accessedResource: C7H10N2OS][accessDate: 05-04-2011] Human CXCL10 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine B10 protein, plays a role in both immune cell migration and in the modulation of adhesion molecule expression. Human CXCL10 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine B10 protein, plays a role in both immune cell migration and in the modulation of adhesion molecule expression.[accessedResource: C7H10N2OS][accessDate: 05-04-2011] IFI10 IFI10[accessedResource: C7H10N2OS][accessDate: 05-04-2011] INP10 INP10[accessedResource: C7H10N2OS][accessDate: 05-04-2011] IP-10 IP-10[accessedResource: C7H10N2OS][accessDate: 05-04-2011] InChI=1/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)/f/h8-9H InChIKey=KNAHARQHSZJURB-DEPUQRHOCL MOB-1 MOB-1[accessedResource: C7H10N2OS][accessDate: 05-04-2011] PTU Propylthiouracil SCYB10 SCYB10[accessedResource: C7H10N2OS][accessDate: 05-04-2011] Tegretol gIP-10 gIP-10[accessedResource: C7H10N2OS][accessDate: 05-04-2011] quetiapine 111974-69-7 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol 2-{[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethyl]oxy}ethanol 23546 3546 A dibenzothiazepine that has formula C21H25N3O2S. C21 C21H25N3O2S C21H25N3O2S C21[accessedResource: C21H25N3O2S][accessDate: 05-04-2011] DC42 DC42[accessedResource: C21H25N3O2S][accessDate: 05-04-2011] FLJ12894 FLJ12894[accessedResource: C21H25N3O2S][accessDate: 05-04-2011] Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia. Human TBL1XR1 wild-type allele is located in the vicinity of 3q26.32 and is approximately 186 kb in length. This allele, which encodes F-box-like/WD repeat-containing protein TBL1XR1, plays a role in activation of transcription. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia.[accessedResource: C21H25N3O2S][accessDate: 05-04-2011] IRA1 IRA1[accessedResource: C21H25N3O2S][accessDate: 05-04-2011] InChI=1/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 InChIKey=URKOMYMAXPYINW-UHFFFAOYAD OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 TBL1XR1 wt Allele TBL1XR1 wt Allele[accessedResource: C21H25N3O2S][accessDate: 05-04-2011] TBLR1 TBLR1[accessedResource: C21H25N3O2S][accessDate: 05-04-2011] Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele Transducin (Beta)-Like 1 X-Linked Receptor 1 wt Allele[accessedResource: C21H25N3O2S][accessDate: 05-04-2011] Transducin (Beta)-Like 1X-Linked Receptor 1 Gene Transducin (Beta)-Like 1X-Linked Receptor 1 Gene[accessedResource: C21H25N3O2S][accessDate: 05-04-2011] quetiapina quetiapinum raloxifene (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone A benzothiophene that has formula C28H27NO4S. C28H27NO4S CHEBI:8772 InChI=1/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2 InChIKey=GZUITABIAKMVPG-UHFFFAOYAG James Malone LY 139481 Oc1ccc(cc1)-c2sc3cc(O)ccc3c2C(=O)c4ccc(OCCN5CCCCC5)cc4 [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl][4-(2-piperidin-1-ylethoxy)phenyl]methanone http://www.ebi.ac.uk/efo/EFO_0001601 raloxifeno raloxifenum rofecoxib 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one A butenolide that has formula C17H14O4S. A sulfone that has formula C17H14O4S. C17H14O4S CHEBI:8887 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 Ceoxx InChI=1/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 InChIKey=RZJQGNCSTQAWON-UHFFFAOYAR Vioxx http://www.ebi.ac.uk/efo/EFO_0001604 sevoflurane 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups. C4H3F7O CHEBI:9130 Ele Holloway FCOC(C(F)(F)F)C(F)(F)F InChI=1/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2 InChIKey=DFEYYRMXOJXZRJ-UHFFFAOYAO Sevofluran Sevoflurano Sevofluranum Tomasz Adamusiak http://www.ebi.ac.uk/efo/EFO_0002733 simvastatin (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate 11q23.1-q23.2 11q23.1-q23.2[accessedResource: C25H38O5][accessDate: 05-04-2011] 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one 23581 3581 79902-63-9 A chromosome band present on 11q A chromosome band present on 11q[accessedResource: C25H38O5][accessDate: 05-04-2011] A fatty acid ester comprising a dihydroxyheptanoic acid unit condensed into a lactone; a partially reduced naphthalene structure; and a 2,2-dimethylbutyric acyl substituent at C17. It is used as a cholesterol-lowering and anti-cardiovascular disease drug. C25H38O5 C25H38O5 InChI=1/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1 InChIKey=RYMZZMVNJRMUDD-HGQWONQEBD MK-733 Simvastatina Simvastatine Simvastatinum Zocor [H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)C(C)(C)CC rapamycin (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone A macrolide that has formula C51H79NO13. Antibiotic AY 22989 C51H79NO13 CHEBI:9168 InChI=1/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33+,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1 InChIKey=QFJCIRLUMZQUOT-KLHQEZAJBI James Malone Rapamune Sirolimus [H][C@]1(CC[C@@H](O)[C@@H](C1)OC)C[C@H](C)[C@]1([H])CC(=O)[C@H](C)\\C=C(C)\\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\\C=C\\C=C\\C=C(C)\\[C@H](C[C@]2([H])CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@@]2([H])C(=O)O1)OC http://www.ebi.ac.uk/efo/EFO_0001602 streptozotocin 2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose 2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-alpha-D-glucopyranose A N-acylglucosamine that has formula C8H15N3O7. An antibiotic that is produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals. C8H15N3O7 CHEBI:9288 CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O InChI=1/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1/f/h9H InChIKey=ZSJLQEPLLKMAKR-CQRXUCDYDU James Malone N-D-Glucosyl-(2)-N&#39;-nitrosomethylharnstoff N-D-Glucosyl-(2)-N'-nitrosomethylurea Streptozocin (TN ZANOSAR) Streptozocinium Zanosar estreptozocina http://www.ebi.ac.uk/efo/EFO_0001615 streptozocin streptozocine streptozocinum sulindac (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid A sulfoxide that has formula C20H17FO3S. C20H17FO3S CC1=C(CC(O)=O)c2cc(F)ccc2\\C1=C/c3ccc(cc3)S(C)=O CHEBI:9352 Clinoril InChI=1/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-/f/h22H InChIKey=MLKXDPUZXIRXEP-CFZDBRNIDX James Malone Sulindacum cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid http://www.ebi.ac.uk/efo/EFO_0001618 sulindaco {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid thapsigargin (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6-dimethyl-8-{[(3Z)-3-methylpent-3-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate 20621 40621 67526-95-8 A hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations. ABDOMINAL CRAMPS ABDOMINAL CRAMPS[accessedResource: C34H50O12][accessDate: 05-04-2011] Abdominal Cramp Abdominal Cramp[accessedResource: C34H50O12][accessDate: 05-04-2011] An involuntary muscular contraction involving a muscle of the abdomen or of a hollow organ within the abdomen. An involuntary muscular contraction involving a muscle of the abdomen or of a hollow organ within the abdomen.[accessedResource: C34H50O12][accessDate: 05-04-2011] C34H50O12 CRAMPS, ABDOMINAL CRAMPS, ABDOMINAL[accessedResource: C34H50O12][accessDate: 05-04-2011] InChI=1/C34H50O12/c1-9-12-13-14-15-17-24(37)43-28-26-25(20(5)27(28)44-30(38)19(4)11-3)29-34(41,33(8,40)31(39)45-29)22(42-23(36)16-10-2)18-32(26,7)46-21(6)35/h11,22,26-29,40-41H,9-10,12-18H2,1-8H3/b19-11-/t22-,26+,27-,28-,29-,32-,33+,34+/m0/s1 InChIKey=IXFPJGBNCFXKPI-FSIHEZPIBR Tg [H][C@@]1(OC(=O)C(\\C)=C/C)[C@@H](OC(=O)CCCCCCC)[C@@]2([H])C(=C1C)[C@]1([H])OC(=O)[C@@](C)(O)[C@@]1(O)[C@H](C[C@]2(C)OC(C)=O)OC(=O)CCC octanoic acid {3S-[3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]}-6-(acetoxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4,5-b]furan-7-yl ester thapsigargine thioridazine 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position. A phenothiazine that has formula C21H26N2S2. C21H26N2S2 CHEBI:9566 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 InChIKey=KLBQZWRITKRQQV-UHFFFAOYAE Mallorol Malloryl Meleril Mellaril Mellaril-S Mellerets Mellerette Melleril Orsanil Sonapax Thioridazin http://www.ebi.ac.uk/efo/EFO_0001625 thioridazinum tioridazina tomatidine (22S,25S)-5alpha-spirosolan-3beta-ol (3beta,5alpha,22beta,25S)-spirosolan-3-ol 5alpha-tomatidan-3beta-ol C27H45NO2 CHEBI:9629 InChI=1/C27H45NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28-29H,5-15H2,1-4H3/t16-,17-,18-,19-,20+,21-,22-,23-,24-,25-,26-,27-/m0/s1 InChIKey=XYNPYHXGMWJBLV-VXPJTDKGBR Tomatidin [H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3([H])C[C@]3([H])O[C@@]5(CC[C@H](C)CN5)[C@@H](C)[C@]43[H])[C@@]1(C)CC[C@H](O)C2 http://www.ebi.ac.uk/efo/EFO_0001627 tomatine (22S,25S)-5alpha-spirosolan-3beta-yl beta-D-glucopyranosyl-(1->2)-[beta-D-xylopyranosyl-(1->3)]-beta-D-glucopyranosyl-(1->4)-beta-D-galactopyranoside (3beta,5alpha,22beta,25S)-spirosolan-3-yl O-beta-D-glucopyranosyl-(1->2)-O-(beta-D-xylopyranosyl)-(1->3)-O-beta-D-glucopyranosyl-(1->4)-beta-D-galactopyranoside A spirostanyl glycoside that has formula C50H83NO21. A''-Tomatidine C50H83NO21 CHEBI:9630 InChI=1/C50H83NO21/c1-20-7-12-50(51-15-20)21(2)32-28(72-50)14-26-24-6-5-22-13-23(8-10-48(22,3)25(24)9-11-49(26,32)4)65-45-40(63)37(60)41(31(18-54)68-45)69-47-43(71-46-39(62)36(59)34(57)29(16-52)66-46)42(35(58)30(17-53)67-47)70-44-38(61)33(56)27(55)19-64-44/h20-47,51-63H,5-19H2,1-4H3/t20-,21-,22-,23-,24+,25-,26-,27+,28-,29+,30+,31+,32-,33-,34+,35+,36-,37+,38+,39+,40+,41-,42-,43+,44-,45+,46-,47-,48-,49-,50-/m0/s1 InChIKey=REJLGAUYTKNVJM-SGXCCWNXBK James Malone [H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3([H])C[C@]3([H])O[C@@]5(CC[C@H](C)CN5)[C@@H](C)[C@]43[H])[C@@]1(C)CC[C@@H](C2)O[C@@H]1O[C@H](CO)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O alpha-tomatine http://www.ebi.ac.uk/efo/EFO_0001628 lycopersicin troglitazone (+-)-all-rac-5-(p-((6-Hydroxy-2,5,7,8-tetramethyl-2-chromanyl)methoxy)benzyl)-2,4-thiazolidinedione 5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione 5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione A chromane that has formula C24H27NO5S. C24H27NO5S CHEBI:9753 Cc1c(C)c2OC(C)(CCc2c(C)c1O)COc1ccc(CC2SC(=O)NC2=O)cc1 InChI=1/C24H27NO5S/c1-13-14(2)21-18(15(3)20(13)26)9-10-24(4,30-21)12-29-17-7-5-16(6-8-17)11-19-22(27)25-23(28)31-19/h5-8,19,26H,9-12H2,1-4H3,(H,25,27,28)/f/h25H InChIKey=GXPHKUHSUJUWKP-LNNLXFCOCP James Malone Rezulin (TN) Romglizone http://www.ebi.ac.uk/efo/EFO_0001632 troglitazona troglitazonum sodium valproate 1069-66-5 2-Propylvaleric acid sodium salt 27/09/1946 37072 C8H15NaO2 C8H15O2Na CP25 CP25[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Depakene Encoded by HOXC6 Gene (ANTP Family), 153- and 235-amino acid (27-kD) Homeobox C6 Protein isoforms are highly conserved sequence-specific DNA-binding homeobox transcription repressors that can cooperate with other HOX proteins and may contribute to the breast cell phenotype through co-operative interactions. As part of a developmental regulatory system that provides anterior-posterior positional identity to cells, HOXC6 may regulate the coordinated expression of multiple genes involved in morphogenesis and differentiation. (from LocusLink, Swiss-Prot, OMIM, and NCI) Epilim HHO.C8 HHO.C8[accessedResource: C8H15NaO2][accessDate: 05-04-2011] HOX3C HOX3C[accessedResource: C8H15NaO2][accessDate: 05-04-2011] HOXC6 HOXC6[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Homeobox Protein 3C Homeobox Protein 3C[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Homeobox Protein C6 Homeobox Protein C6[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Homeobox Protein C8 Homeobox Protein C8[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Homeobox Protein CP25 Homeobox Protein CP25[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Homeobox Protein HHO.C8 Homeobox Protein HHO.C8[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Homeobox Protein HOXC6 Homeobox Protein HOXC6[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Homeobox Protein Hox-3C Homeobox Protein Hox-3C[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Homeobox Protein Hox-C6 Homeobox Protein Hox-C6[accessedResource: C8H15NaO2][accessDate: 05-04-2011] Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development. Homeobox protein Hox-C6 (235 aa, ~27 kDa) is encoded by the human HOXC6 gene. This protein plays a role in transcription and embryonic development.[accessedResource: C8H15NaO2][accessDate: 05-04-2011] InChI=1/C8H16O2.Na/c1-3-5-7(6-4-2)8(9)10;/h7H,3-6H2,1-2H3,(H,9,10);/q;+1/p-1/fC8H15O2.Na/q-1;m InChIKey=AEQFSUDEHCCHBT-SKMAPJTGCG The sodium salt of valproic acid. [Na+].CCCC(CCC)C([O-])=O sodium 2-propylpentanoate sodium 2-propylpentanoate chemical role A role played by the molecular entity or part thereof within a chemical context. James Malone The role of a chemical to be an anti-inflammatory drug. http://purl.org/obo/owl/CHEBI#CHEBI_51086 http://www.ebi.ac.uk/efo/EFO_0001815 lipid 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids. A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed) A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)[accessedResource: MSH:D008055][accessDate: 05-04-2011] Lipids Lipids[accessedResource: MSH:D008055][accessDate: 05-04-2011] MSH:D008055 Tomasz Adamusiak true estradiol A steroid hormone that has formula C18H24O2. C18H24O2 InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17?,18+/m1/s1 InChIKey=VOXZDWNPVJITMN-WKUFJEKOBY [H][C@]12CC[C@]3(C)C(O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21 estra-1,3,5(10)-triene-3,17-diol http://www.ebi.ac.uk/efo/EFO_0001529 oestradiol pigment A pigment cell is a cell that contains pigment granules. A pigment cell is a cell that contains pigment granules.[accessedResource: CL:0000147][accessDate: 05-04-2011] AAO:0000430 An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light. CL:0000147 James Malone MAT:0000159 MFO:0003360 NIFSTD:sao1231384859 Tomasz Adamusiak ZFA:0009090 biological pigment chromatocyte chromatocyte[accessedResource: CL:0000147][accessDate: 05-04-2011] chromatophore chromatophore[accessedResource: ZFA:0009090][accessDate: 05-04-2011] http://www.ebi.ac.uk/efo/EFO_0000957 pigment cell pigment cell[accessedResource: ZFA:0009090][accessDate: 05-04-2011] pigment cells pigment cells[accessedResource: MAT:0000159][accessDate: 05-04-2011] pigmentation pigments dehydroepiandrosterone 3beta-hydroxyandrost-5-en-17-one 5 Androsten 3 beta hydroxy 17 one 5 Androsten 3 beta hydroxy 17 one[accessedResource: MSH:D003687][accessDate: 05-04-2011] 5 Androsten 3 ol 17 one 5 Androsten 3 ol 17 one[accessedResource: MSH:D003687][accessDate: 05-04-2011] 5-Androsten-3-beta-hydroxy-17-one 5-Androsten-3-beta-hydroxy-17-one[accessedResource: MSH:D003687][accessDate: 05-04-2011] 5-Androsten-3-ol-17-one 5-Androsten-3-ol-17-one[accessedResource: MSH:D003687][accessDate: 05-04-2011] A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion. A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.[accessedResource: MSH:D003687][accessDate: 05-04-2011] An androgen that has formula C19H28O2. Androst-5-en-17-one, 3-hydroxy-, (3beta)- Androst-5-en-17-one, 3-hydroxy-, (3beta)-[accessedResource: MSH:D003687][accessDate: 05-04-2011] Androstenolone Androstenolone[accessedResource: MSH:D003687][accessDate: 05-04-2011] DHEA DHEA[accessedResource: MSH:D003687][accessDate: 05-04-2011] Dehydroisoandrosterone Dehydroisoandrosterone[accessedResource: MSH:D003687][accessDate: 05-04-2011] MSH:D003687 Prasterone Prasterone, 3 alpha Isomer Prasterone, 3 alpha Isomer[accessedResource: MSH:D003687][accessDate: 05-04-2011] Prasterone, 3 alpha-Isomer Prasterone, 3 alpha-Isomer[accessedResource: MSH:D003687][accessDate: 05-04-2011] Prasterone[accessedResource: MSH:D003687][accessDate: 05-04-2011] Tomasz Adamusiak phosgene CCl2O COCl2 ClC(Cl)=O InChI=1/CCl2O/c2-1(3)4 InChIKey=YGYAWVDWMABLBF-UHFFFAOYAH carbonyl dichloride nutrient A nutrient is a chemical element needed by all life forms. James Malone Jie Zheng MO_867 The food provided to the organism (e.g., chow, fertilizer, DEMM 10%FBS, etc.). Tomasz Adamusiak chow, fertilizer, DEMM 10%FBS http://mged.sourceforge.net/ontologies/MGEDOntology.owl#nutrients http://www.ebi.ac.uk/efo/EFO_0000628 nutrients nutrients[accessedResource: MO_867][accessDate: 05-04-2011] this should become a quality of a material i think protein A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome. A protein is an (also known as polypeptides) organic compound made of amino acids arranged in a linear chain and folded into a globular form. James Malone Jie Zheng MO_683 PRO:000000001 Tomasz Adamusiak http://mged.sourceforge.net/ontologies/MGEDOntology.owl#protein http://www.ebi.ac.uk/efo/EFO_0001459 polypeptide proteins true chemical compound A drug, solvent, chemical, etc., with a property that can be measured such as concentration. A molecular entity consisting of two or more chemical elements. James Malone Tomasz Adamusiak heteroatomic molecular entities heteroatomic molecular entity HDL cholesterol A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases. A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.[accessedResource: MSH:D008075][accessDate: 05-04-2011] Cholesterol esters and free cholesterol which are contained in or bound to high-density lipoproteins (HDL). Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL ESTERS and free cholesterol. Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL ESTERS and free cholesterol.[accessedResource: MSH:D008076][accessDate: 05-04-2011] Cholesterol, HDL Cholesterol, HDL2 Cholesterol, HDL2[accessedResource: MSH:D008076][accessDate: 05-04-2011] Cholesterol, HDL3 Cholesterol, HDL3[accessedResource: MSH:D008076][accessDate: 05-04-2011] Cholesterol, HDL[accessedResource: MSH:D008076][accessDate: 05-04-2011] Cholesterol, alpha-Lipoprotein Cholesterol, alpha-Lipoprotein[accessedResource: MSH:D008076][accessDate: 05-04-2011] HDL Lipoproteins HDL Lipoproteins[accessedResource: MSH:D008075][accessDate: 05-04-2011] HDL(2) Cholesterol HDL(2) Cholesterol[accessedResource: MSH:D008076][accessDate: 05-04-2011] HDL(3) Cholesterol HDL(3) Cholesterol[accessedResource: MSH:D008076][accessDate: 05-04-2011] HDL2 Cholesterol HDL2 Cholesterol[accessedResource: MSH:D008076][accessDate: 05-04-2011] HDL3 Cholesterol HDL3 Cholesterol[accessedResource: MSH:D008076][accessDate: 05-04-2011] Heavy Lipoproteins Heavy Lipoproteins[accessedResource: MSH:D008075][accessDate: 05-04-2011] High Density Lipoprotein Cholesterol High Density Lipoprotein Cholesterol[accessedResource: MSH:D008076][accessDate: 05-04-2011] High Density Lipoproteins High Density Lipoproteins[accessedResource: MSH:D008075][accessDate: 05-04-2011] High-Density Lipoproteins High-Density Lipoproteins[accessedResource: MSH:D008075][accessDate: 05-04-2011] Lipoproteins, HDL Lipoproteins, HDL[accessedResource: MSH:D008075][accessDate: 05-04-2011] Lipoproteins, Heavy Lipoproteins, Heavy[accessedResource: MSH:D008075][accessDate: 05-04-2011] Lipoproteins, High-Density Lipoproteins, High-Density[accessedResource: MSH:D008075][accessDate: 05-04-2011] MSH:D008075 MSH:D008076 Tomasz Adamusiak alpha Lipoprotein Cholesterol alpha Lipoprotein Cholesterol[accessedResource: MSH:D008076][accessDate: 05-04-2011] alpha Lipoproteins alpha Lipoproteins[accessedResource: MSH:D008075][accessDate: 05-04-2011] alpha-1 Lipoprotein alpha-1 Lipoprotein[accessedResource: MSH:D008075][accessDate: 05-04-2011] alpha-Lipoprotein Cholesterol alpha-Lipoprotein Cholesterol[accessedResource: MSH:D008076][accessDate: 05-04-2011] alpha-Lipoproteins alpha-Lipoproteins[accessedResource: MSH:D008075][accessDate: 05-04-2011] high-density lipoprotein cholesterol true epigallocatechin gallate (-)-Epigallocatechin-3-o-gallate (-)-epigallocatechin 3-gallate (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate EGCG InChI=1/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1 InChIKey=WMBWREPUVVBILR-WIYYLYMNBM Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1cc(O)c(O)c(O)c1 http://www.ebi.ac.uk/efo/EFO_0002670 experimental factor An experimental factor in Array Express which are essentially the variable aspects of an experiment design which can be used to describe an experiment, or set of experiments, in an increasingly detailed manner. An experimental factor in Array Express. Concept naming convention is lower case natural naming with spaces, when necessary captials should be used, for example disease factor, HIV, breast carcinoma, Ewing's sarcoma ExperimentalFactor ExperimentalFactor[accessedResource: MO_10][accessDate: 05-04-2011] Helen Parkinson Helen Parkinson James Malone James Malone Jie Zheng MO_10 Tomasz Adamusiak Tomasz Adamusiak true CS57511 CS57511 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311932. James Malone http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311932 CS57512 CS57512 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311933 James Malone http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311933 CS57515 CS57515 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311936 James Malone http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311936 CS57520 CS57520 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311941 James Malone http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311941 CS57521 CS57521 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?type=germplasm&id=1005152522 James Malone http://www.arabidopsis.org/servlets/TairObject?type=germplasm&id=1005152522 CS57537 CS57537 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311958 James Malone http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311958 CS57541 CS57541 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158565&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158565&type=germplasm CS57543 CS57543 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158567&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158567&type=germplasm CS57544 CS57544 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158568&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158568&type=germplasm CS57548 CS57548 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158572&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158572&type=germplasm CS57549 CS57549 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158573&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158573&type=germplasm CS57551 CS57551 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158575&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158575&type=germplasm CS57556 CS57556 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158580&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158580&type=germplasm CS57560 CS57560 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158584&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158584&type=germplasm CS57563 CS57563 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311984 James Malone http://www.arabidopsis.org/servlets/TairObject?type=stock&id=1000311984 CS57569 CS57569 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158593&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158593&type=germplasm CS57570 CS57570 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158594&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158594&type=germplasm CS57572 CS57572 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158596&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158596&type=germplasm CS57580 CS57580 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158604&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158604&type=germplasm CS57581 CS57581 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158605&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158605&type=germplasm CS57583 CS57583 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158607&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158607&type=germplasm CS57586 CS57586 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158610&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158610&type=germplasm CS57587 CS57587 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158611&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158611&type=germplasm CS57591 CS57591 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158615&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158615&type=germplasm CS57595 CS57595 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158619&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158619&type=germplasm CS57596 CS57596 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158620&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158620&type=germplasm CS57598 CS57598 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158622&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158622&type=germplasm CS57601 CS57601 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158625&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158625&type=germplasm CS57603 CS57603 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158627&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158627&type=germplasm CS57606 CS57606 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158630&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158630&type=germplasm CS57610 CS57610 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158634&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158634&type=germplasm CS57615 CS57615 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158639&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158639&type=germplasm CS57616 CS57616 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158640&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158640&type=germplasm CS57618 CS57618 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158642&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158642&type=germplasm CS57619 CS57619 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158643&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158643&type=germplasm CS57620 CS57620 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158644&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158644&type=germplasm CS57621 CS57621 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158645&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158645&type=germplasm CS57622 CS57622 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158646&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158646&type=germplasm CS57624 CS57624 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158648&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158648&type=germplasm CS57625 CS57625 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158649&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158649&type=germplasm CS57626 CS57626 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158650&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158650&type=germplasm CS57627 CS57627 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158651&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158651&type=germplasm CS57628 CS57628 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158652&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158652&type=germplasm CS57629 CS57629 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158653&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158653&type=germplasm CS57630 CS57630 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158654&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158654&type=germplasm CS57631 CS57631 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158655&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158655&type=germplasm CS57637 CS57637 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158661&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158661&type=germplasm CS57641 CS57641 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158665&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158665&type=germplasm CS57644 CS57644 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158668&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158668&type=germplasm CS57646 CS57646 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158670&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158670&type=germplasm CS57648 CS57648 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158672&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158672&type=germplasm CS57655 CS57655 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158679&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158679&type=germplasm CS57658 CS57658 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158682&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158682&type=germplasm CS57660 CS57660 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158684&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158684&type=germplasm CS57663 CS57663 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158687&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158687&type=germplasm CS57664 CS57664 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158688&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158688&type=germplasm CS57666 CS57664 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158690&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158690&type=germplasm CS57671 CS57671 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158695&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158695&type=germplasm CS57677 CS57677 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158695&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158701&type=germplasm CS57691 CS57691 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158715&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158715&type=germplasm CS57692 CS57692 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158716&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158716&type=germplasm CS57699 CS57699 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158723&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158723&type=germplasm CS57701 CS57701 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158725&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158725&type=germplasm CS57704 CS57704 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158728&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158728&type=germplasm CS57705 CS57705 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158729&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158729&type=germplasm CS57706 CS57706 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158730&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158730&type=germplasm CS57709 CS57709 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158733&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158733&type=germplasm CS57710 CS57710 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158734&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158734&type=germplasm CS57714 CS57714 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158738&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158738&type=germplasm CS57715 CS57715 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158739&type=germplasm James Malone http://www.arabidopsis.org/servlets/TairObject?id=1005158739&type=germplasm CS57716 CS57716 is an Arabidopsis thaliana strain as described in TAIR http://www.arabidopsis.org/servlets/TairObject?id=1005158740&type=germplasm